ES8105308A1 - Procedimiento para la fabricacion de 4-tiazolidonas,2-subs- tituidas - Google Patents
Procedimiento para la fabricacion de 4-tiazolidonas,2-subs- tituidasInfo
- Publication number
- ES8105308A1 ES8105308A1 ES493649A ES493649A ES8105308A1 ES 8105308 A1 ES8105308 A1 ES 8105308A1 ES 493649 A ES493649 A ES 493649A ES 493649 A ES493649 A ES 493649A ES 8105308 A1 ES8105308 A1 ES 8105308A1
- Authority
- ES
- Spain
- Prior art keywords
- thiazolidones
- substituted
- producing
- disclosed
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE 4-TIAZOLIDONAS, 2-SUSTITUIDAS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (I) CON UNA CANTIDAD EQUIMOLECULAR O UN LIGERO EXCESO DE ACIDAMIDA TIOGLICOLICA EN UN DISOLVENTE INERTE TAL COMO BENCENO, TOLUENO O XILENO. LA REACCION SE EFECTUA A UNA TEMPERATURA QUE OSCILA ENTRE 50 Y 150GC. EL TIEMPO ES DE 1 A 10 HORAS, ELIMINANDOSE EL AGUA FORMADA DURANTE LA REACCION. SE OBTIENE EL COMPUESTO II, EN QUE R ES UN GRUPO METOXI, ETOXI, HIDROXILO, CARBOXILO, METILENDIOXI Y DIMETILAMINO <<N>> VALE DE 1 A 3. *FORMULA* TRATAMIENTO DE ULCERAS PEPTICAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8705679A JPS5612376A (en) | 1979-07-09 | 1979-07-09 | Novel thiazolidone derivative, its preparation, and drug for ulcer having antidigestive action |
JP6850680A JPS56164174A (en) | 1980-05-23 | 1980-05-23 | Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8105308A1 true ES8105308A1 (es) | 1981-06-01 |
ES493649A0 ES493649A0 (es) | 1981-06-01 |
Family
ID=26409722
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES493649A Granted ES493649A0 (es) | 1979-07-09 | 1980-07-09 | Procedimiento para la fabricacion de 4-tiazolidonas,2-subs- tituidas |
ES500075A Expired ES8202545A1 (es) | 1979-07-09 | 1981-02-13 | Metodo perfeccionado para la fabricacion de 4-tiazolidonas,2-substituidas |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES500075A Expired ES8202545A1 (es) | 1979-07-09 | 1981-02-13 | Metodo perfeccionado para la fabricacion de 4-tiazolidonas,2-substituidas |
Country Status (7)
Country | Link |
---|---|
US (2) | US4540702A (es) |
CA (1) | CA1154447A (es) |
DE (1) | DE3026053C2 (es) |
ES (2) | ES493649A0 (es) |
FR (1) | FR2468598B1 (es) |
GB (1) | GB2055816B (es) |
IT (1) | IT1131681B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1154447A (en) * | 1979-07-09 | 1983-09-27 | Takao Kawasaki | 2-substituted-4-thiazolidones |
JPS6052747B2 (ja) * | 1980-10-09 | 1985-11-21 | 呉羽化学工業株式会社 | 2−置換フエニル−5−アルキルチアゾリジン−4−オン、及び該化合物有効成分とする抗消化性潰瘍剤 |
JPS5764685A (en) | 1980-10-09 | 1982-04-19 | Kureha Chem Ind Co Ltd | 2-(substituted phenyl)-1,3-thiazin-4(3,5,6h)-one and remedy for peptic ulcer containing said compound as active component |
EP0206318B1 (en) * | 1985-06-25 | 1990-04-11 | Ishihara Sangyo Kaisha, Ltd. | Organophosphorus compounds, process for their preparation and insecticidal, miticidal, nematicidal or soil pesticidal compositions containing them |
US5017591A (en) * | 1987-07-28 | 1991-05-21 | Merrell Dow Pharmaceuticals | Thiazolyl methyl)-2-2'-Bi-1H-imidazoles and use as hypertensive agents |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3187002A (en) * | 1965-06-01 | Hs-chxcook | ||
US2520178A (en) * | 1948-03-19 | 1950-08-29 | Sterling Drug Inc | 2, 3-diaryl-4-thiazolidones and their preparation |
US2623048A (en) * | 1948-04-05 | 1952-12-23 | Parke Davis & Co | 4-thiazolidone derivatives and process for preparing the same |
GB1345159A (en) * | 1970-06-26 | 1974-01-30 | Ici Ltd | Oxathiolanone and thiazolidinone derivatives |
US4053471A (en) * | 1976-11-11 | 1977-10-11 | E. R. Squibb & Sons, Inc. | 4-thiazolidinone derivatives |
CA1154447A (en) * | 1979-07-09 | 1983-09-27 | Takao Kawasaki | 2-substituted-4-thiazolidones |
JPS6052747B2 (ja) * | 1980-10-09 | 1985-11-21 | 呉羽化学工業株式会社 | 2−置換フエニル−5−アルキルチアゾリジン−4−オン、及び該化合物有効成分とする抗消化性潰瘍剤 |
-
1980
- 1980-07-04 CA CA000355457A patent/CA1154447A/en not_active Expired
- 1980-07-08 FR FR8015205A patent/FR2468598B1/fr not_active Expired
- 1980-07-08 IT IT23314/80A patent/IT1131681B/it active
- 1980-07-08 GB GB8022293A patent/GB2055816B/en not_active Expired
- 1980-07-09 ES ES493649A patent/ES493649A0/es active Granted
- 1980-07-09 DE DE3026053A patent/DE3026053C2/de not_active Expired
-
1981
- 1981-02-13 ES ES500075A patent/ES8202545A1/es not_active Expired
-
1982
- 1982-08-30 US US06/412,964 patent/US4540702A/en not_active Expired - Fee Related
-
1985
- 1985-08-30 US US06/708,556 patent/US4722932A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE3026053A1 (de) | 1981-02-05 |
DE3026053C2 (de) | 1982-07-01 |
US4722932A (en) | 1988-02-02 |
ES500075A0 (es) | 1982-02-01 |
IT8023314A0 (it) | 1980-07-08 |
ES8202545A1 (es) | 1982-04-01 |
GB2055816A (en) | 1981-03-11 |
GB2055816B (en) | 1983-05-11 |
IT1131681B (it) | 1986-06-25 |
FR2468598A1 (fr) | 1981-05-08 |
ES493649A0 (es) | 1981-06-01 |
US4540702A (en) | 1985-09-10 |
CA1154447A (en) | 1983-09-27 |
FR2468598B1 (fr) | 1986-03-07 |
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