JPS56164174A - Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same - Google Patents
Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the sameInfo
- Publication number
- JPS56164174A JPS56164174A JP6850680A JP6850680A JPS56164174A JP S56164174 A JPS56164174 A JP S56164174A JP 6850680 A JP6850680 A JP 6850680A JP 6850680 A JP6850680 A JP 6850680A JP S56164174 A JPS56164174 A JP S56164174A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- novel
- preparation
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A 2-substituted-4-thiazolidone derivative of formula I (R is methylenedioxyphenyl, hydroxyphenyl, carboxyphenyl, di-lower alkylaminophenyl, thienyl, mono- or di-lower alkoxyphenyl or hydroxy-di-lower alkoxyphenyl).
EXAMPLE: 2-(2-Methoxyphenyl)4-thiazolidone.
USE: An antipeptic ulcer agent.
PROCESS: An aldehyde compound of formula II is reacted with a thioglycollic amide of formula II in an inert solvent, e.g. benzene, at the boiling point of the solvent, for 1W10hr to give the compound of formula I. Alternatively, the compound of formula II is reacted with a compound of formula III at 10W50°C for 2W10min, and the resultant intermediate of formula IV is then cyclized at 50W150°C for 0.5W10hr to afford the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6850680A JPS56164174A (en) | 1980-05-23 | 1980-05-23 | Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same |
CA000355457A CA1154447A (en) | 1979-07-09 | 1980-07-04 | 2-substituted-4-thiazolidones |
GB8022293A GB2055816B (en) | 1979-07-09 | 1980-07-08 | Thiazolidones |
IT23314/80A IT1131681B (en) | 1979-07-09 | 1980-07-08 | 4-THIAZOLIDONES 2-USEFUL SUBSTITUTES AS DRUGS AND PROCEDURE FOR THEIR PREPARATION |
FR8015205A FR2468598B1 (en) | 1979-07-09 | 1980-07-08 | THIAZOLIDONES-4 SUBSTITUTED IN 2, THEIR PREPARATION PROCESS AND THE MEDICINES CONTAINING THEM |
DE3026053A DE3026053C2 (en) | 1979-07-09 | 1980-07-09 | 2-substituted-4-thiazolidones |
ES493649A ES493649A0 (en) | 1979-07-09 | 1980-07-09 | PROCEDURE FOR THE MANUFACTURE OF 4-THIAZOLIDONES, 2-SUBS- TITUIDES |
ES500075A ES8202545A1 (en) | 1979-07-09 | 1981-02-13 | 2-Substituted-4-thiazolidones |
US06/412,964 US4540702A (en) | 1979-07-09 | 1982-08-30 | 2-Substituted-4-thiazolidones |
US06/708,556 US4722932A (en) | 1979-07-09 | 1985-08-30 | 2-substituted-4-thiazolidones |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6850680A JPS56164174A (en) | 1980-05-23 | 1980-05-23 | Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56164174A true JPS56164174A (en) | 1981-12-17 |
JPS6310949B2 JPS6310949B2 (en) | 1988-03-10 |
Family
ID=13375649
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6850680A Granted JPS56164174A (en) | 1979-07-09 | 1980-05-23 | Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56164174A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100329808B1 (en) * | 2000-01-14 | 2002-03-25 | 박호군 | An efficient method for preparing 2-phenacylidene-3,5-dialkylsubstituted-1,3-thiazolidine-4-ones |
-
1980
- 1980-05-23 JP JP6850680A patent/JPS56164174A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100329808B1 (en) * | 2000-01-14 | 2002-03-25 | 박호군 | An efficient method for preparing 2-phenacylidene-3,5-dialkylsubstituted-1,3-thiazolidine-4-ones |
Also Published As
Publication number | Publication date |
---|---|
JPS6310949B2 (en) | 1988-03-10 |
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