JPS56164174A - Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same - Google Patents

Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same

Info

Publication number
JPS56164174A
JPS56164174A JP6850680A JP6850680A JPS56164174A JP S56164174 A JPS56164174 A JP S56164174A JP 6850680 A JP6850680 A JP 6850680A JP 6850680 A JP6850680 A JP 6850680A JP S56164174 A JPS56164174 A JP S56164174A
Authority
JP
Japan
Prior art keywords
formula
compound
novel
preparation
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6850680A
Other languages
Japanese (ja)
Other versions
JPS6310949B2 (en
Inventor
Takao Kawasaki
Yoshiaki Osaka
Tadashi Tsuchiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Priority to JP6850680A priority Critical patent/JPS56164174A/en
Priority to CA000355457A priority patent/CA1154447A/en
Priority to GB8022293A priority patent/GB2055816B/en
Priority to IT23314/80A priority patent/IT1131681B/en
Priority to FR8015205A priority patent/FR2468598B1/en
Priority to DE3026053A priority patent/DE3026053C2/en
Priority to ES493649A priority patent/ES493649A0/en
Priority to ES500075A priority patent/ES8202545A1/en
Publication of JPS56164174A publication Critical patent/JPS56164174A/en
Priority to US06/412,964 priority patent/US4540702A/en
Priority to US06/708,556 priority patent/US4722932A/en
Publication of JPS6310949B2 publication Critical patent/JPS6310949B2/ja
Granted legal-status Critical Current

Links

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  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A 2-substituted-4-thiazolidone derivative of formula I (R is methylenedioxyphenyl, hydroxyphenyl, carboxyphenyl, di-lower alkylaminophenyl, thienyl, mono- or di-lower alkoxyphenyl or hydroxy-di-lower alkoxyphenyl).
EXAMPLE: 2-(2-Methoxyphenyl)4-thiazolidone.
USE: An antipeptic ulcer agent.
PROCESS: An aldehyde compound of formula II is reacted with a thioglycollic amide of formula II in an inert solvent, e.g. benzene, at the boiling point of the solvent, for 1W10hr to give the compound of formula I. Alternatively, the compound of formula II is reacted with a compound of formula III at 10W50°C for 2W10min, and the resultant intermediate of formula IV is then cyclized at 50W150°C for 0.5W10hr to afford the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP6850680A 1979-07-09 1980-05-23 Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same Granted JPS56164174A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP6850680A JPS56164174A (en) 1980-05-23 1980-05-23 Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same
CA000355457A CA1154447A (en) 1979-07-09 1980-07-04 2-substituted-4-thiazolidones
GB8022293A GB2055816B (en) 1979-07-09 1980-07-08 Thiazolidones
IT23314/80A IT1131681B (en) 1979-07-09 1980-07-08 4-THIAZOLIDONES 2-USEFUL SUBSTITUTES AS DRUGS AND PROCEDURE FOR THEIR PREPARATION
FR8015205A FR2468598B1 (en) 1979-07-09 1980-07-08 THIAZOLIDONES-4 SUBSTITUTED IN 2, THEIR PREPARATION PROCESS AND THE MEDICINES CONTAINING THEM
DE3026053A DE3026053C2 (en) 1979-07-09 1980-07-09 2-substituted-4-thiazolidones
ES493649A ES493649A0 (en) 1979-07-09 1980-07-09 PROCEDURE FOR THE MANUFACTURE OF 4-THIAZOLIDONES, 2-SUBS- TITUIDES
ES500075A ES8202545A1 (en) 1979-07-09 1981-02-13 2-Substituted-4-thiazolidones
US06/412,964 US4540702A (en) 1979-07-09 1982-08-30 2-Substituted-4-thiazolidones
US06/708,556 US4722932A (en) 1979-07-09 1985-08-30 2-substituted-4-thiazolidones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6850680A JPS56164174A (en) 1980-05-23 1980-05-23 Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same

Publications (2)

Publication Number Publication Date
JPS56164174A true JPS56164174A (en) 1981-12-17
JPS6310949B2 JPS6310949B2 (en) 1988-03-10

Family

ID=13375649

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6850680A Granted JPS56164174A (en) 1979-07-09 1980-05-23 Novel thiazolidone derivative, its preparation and antipeptic ulcer agent containing the same

Country Status (1)

Country Link
JP (1) JPS56164174A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100329808B1 (en) * 2000-01-14 2002-03-25 박호군 An efficient method for preparing 2-phenacylidene-3,5-dialkylsubstituted-1,3-thiazolidine-4-ones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100329808B1 (en) * 2000-01-14 2002-03-25 박호군 An efficient method for preparing 2-phenacylidene-3,5-dialkylsubstituted-1,3-thiazolidine-4-ones

Also Published As

Publication number Publication date
JPS6310949B2 (en) 1988-03-10

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