FR2466472B1 - - Google Patents

Info

Publication number
FR2466472B1
FR2466472B1 FR8021170A FR8021170A FR2466472B1 FR 2466472 B1 FR2466472 B1 FR 2466472B1 FR 8021170 A FR8021170 A FR 8021170A FR 8021170 A FR8021170 A FR 8021170A FR 2466472 B1 FR2466472 B1 FR 2466472B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8021170A
Other versions
FR2466472A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Birmingham
Original Assignee
University of Birmingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Birmingham filed Critical University of Birmingham
Publication of FR2466472A1 publication Critical patent/FR2466472A1/fr
Application granted granted Critical
Publication of FR2466472B1 publication Critical patent/FR2466472B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR8021170A 1979-10-03 1980-10-02 E-5-(2-halogenovinyl)-2'-desoxycytydines; leur procede de preparation et leur utilisation dans des compositions pharmaceutiques pour le traitement de maladies a virus Granted FR2466472A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7934248A GB2060604B (en) 1979-10-03 1979-10-03 E15-(2-halogenovinyl)-2'-deoxycytidines

Publications (2)

Publication Number Publication Date
FR2466472A1 FR2466472A1 (fr) 1981-04-10
FR2466472B1 true FR2466472B1 (fr) 1983-12-23

Family

ID=10508255

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8021170A Granted FR2466472A1 (fr) 1979-10-03 1980-10-02 E-5-(2-halogenovinyl)-2'-desoxycytydines; leur procede de preparation et leur utilisation dans des compositions pharmaceutiques pour le traitement de maladies a virus

Country Status (11)

Country Link
US (1) US4382925A (fr)
JP (1) JPS5695198A (fr)
BE (1) BE885415A (fr)
CA (1) CA1173438A (fr)
CH (1) CH647245A5 (fr)
DE (1) DE3036131A1 (fr)
FR (1) FR2466472A1 (fr)
GB (1) GB2060604B (fr)
IT (1) IT1209758B (fr)
NL (1) NL8005336A (fr)
SE (1) SE445740B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ199764A (en) * 1981-03-20 1984-08-24 Beecham Group Plc 5-(2-halogenovinyl)-2'-deoxyuridine derivatives and pharmaceutical compositions
HU183567B (en) * 1981-09-07 1984-05-28 Mta Koezponti Kemiai Kutato In Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof
JPS5843993A (ja) * 1981-09-09 1983-03-14 Yamasa Shoyu Co Ltd １−β−Ｄ−アラビノフラノシル−（Ｅ）−５−（２−ハロゲノビニル）ウラシル−５′−りん酸およびその製造法
EP0080305A1 (fr) * 1981-11-19 1983-06-01 Beecham Group Plc 2'-Déoxyuridines à activité antivirale, leur préparation et emploi
EP0082668A1 (fr) * 1981-12-18 1983-06-29 Beecham Group Plc 5-(2-Halogénovinyl)-2'-déoxyuridines, leurs méthodes de préparation, compositions pharmaceutiques les contenant et leur emploi dans le traitement d'infections virales
US4782142A (en) * 1982-01-05 1988-11-01 The Research Foundation Of State University Of New York Novel 5-substituted 2-pyrimidinone nucleosides and methods of use
FR2531962B1 (fr) * 1982-08-17 1986-11-14 Sandoz Sa Nouveaux derives de la desoxyuridine, leur preparation et leur utilisation comme medicaments
CA1257595A (fr) * 1982-09-17 1989-07-18 Glaxo Group Ltd Derives de 5-halogenovinyl-2'-desoxyuridine
HU198393B (en) * 1984-03-06 1989-10-30 Sloan Kettering Inst Cancer Process for production of medical composition suitable for treatment of hepatitis containing as active substance derivatives of piramidin-nucleoside
US4666892A (en) * 1984-03-06 1987-05-19 Sloan-Kettering Memorial Cancer Center Method and composition for hepatitis treatment with pyrimidine nucleoside compounds
US4762823A (en) * 1985-10-16 1988-08-09 Sloan-Kettering Institute For Cancer Research Nucleosides of 5-monofluoromethyluracil and 5-difluoromethyluracil
US5215971A (en) * 1986-12-19 1993-06-01 Medivir Ab Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
SE8605503D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel medicinal use
EP0428623A4 (en) * 1988-08-10 1993-12-08 Stephen Leslie Sacks Production of radioiodinated 1--g(b)-d-arabinofuranosyl)-5(e)-(2-iodovinyl)uracil, and uses thereof, and related analogues incorporating alternative halogen radionuclides, the general radiohalogenation precursors, 1-(2,3,5-tri-o-acetyl--g(b)-d-arabinofuranosyl)-5(z and e)-(2-trimethylsilylvinyl)urac
DK1284720T3 (da) 2000-03-29 2007-01-15 Univ Georgetown L-FMAU til behandling af hepatitis delta-virusinfektion
WO2003053360A2 (fr) * 2001-12-20 2003-07-03 Pharmassett Ltd. Traitement du virus d'epstein-barr, infection a l'herpesvirus lie au sarcome de kaposi et proliferation cellulaire anormale associee
JP2008174524A (ja) * 2007-01-22 2008-07-31 Nippon Shinyaku Co Ltd リボ核酸化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354160A (en) * 1965-07-22 1967-11-21 Hoffmann La Roche Tri-lower alkyl-silyl-5-fluoropyrimidines
US4000260A (en) * 1974-08-29 1976-12-28 Research Corporation Anti herpes simplex viral compounds and their synthesis
US4024143A (en) * 1976-03-11 1977-05-17 Pcr, Inc. Silylation of 5-fluoro-6-hydroxy or alkoxy pyrimidine
US4267171A (en) * 1979-07-02 1981-05-12 The Regents Of The University Of California C-5 Substituted cytosine nucleosides

Also Published As

Publication number Publication date
FR2466472A1 (fr) 1981-04-10
JPS5695198A (en) 1981-08-01
JPS637199B2 (fr) 1988-02-15
GB2060604A (en) 1981-05-07
IT8009551A0 (it) 1980-10-02
NL8005336A (nl) 1981-04-07
DE3036131C2 (fr) 1989-07-06
DE3036131A1 (de) 1981-04-16
SE8006669L (sv) 1981-04-04
US4382925A (en) 1983-05-10
SE445740B (sv) 1986-07-14
GB2060604B (en) 1983-11-23
CH647245A5 (de) 1985-01-15
BE885415A (nl) 1981-03-26
CA1173438A (fr) 1984-08-28
IT1209758B (it) 1989-08-30

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Legal Events

Date Code Title Description
ST Notification of lapse