SE8006669L - E-5-(halogenovinyl)-2'-deoxicytidiner och sett for framstellning derav - Google Patents

E-5-(halogenovinyl)-2'-deoxicytidiner och sett for framstellning derav

Info

Publication number
SE8006669L
SE8006669L SE8006669A SE8006669A SE8006669L SE 8006669 L SE8006669 L SE 8006669L SE 8006669 A SE8006669 A SE 8006669A SE 8006669 A SE8006669 A SE 8006669A SE 8006669 L SE8006669 L SE 8006669L
Authority
SE
Sweden
Prior art keywords
halogenovinyl
deoxycytidine
deoxicytidines
preparing
sets
Prior art date
Application number
SE8006669A
Other languages
English (en)
Other versions
SE445740B (sv
Inventor
A S Jones
R T Walker
Clercq E De
G A Verhelst
Original Assignee
Univ Birmingham
Stichting Rega V Z W
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Birmingham, Stichting Rega V Z W filed Critical Univ Birmingham
Publication of SE8006669L publication Critical patent/SE8006669L/sv
Publication of SE445740B publication Critical patent/SE445740B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SE8006669A 1979-10-03 1980-09-24 E-5-(2-halogenvinyl)-2'-deoxicytidin, sett for framstellning derav samt farmaceutisk komposition innehallande e-5-(2-halogenvinyl)-2'-deoxicytidin SE445740B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7934248A GB2060604B (en) 1979-10-03 1979-10-03 E15-(2-halogenovinyl)-2'-deoxycytidines

Publications (2)

Publication Number Publication Date
SE8006669L true SE8006669L (sv) 1981-04-04
SE445740B SE445740B (sv) 1986-07-14

Family

ID=10508255

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8006669A SE445740B (sv) 1979-10-03 1980-09-24 E-5-(2-halogenvinyl)-2'-deoxicytidin, sett for framstellning derav samt farmaceutisk komposition innehallande e-5-(2-halogenvinyl)-2'-deoxicytidin

Country Status (11)

Country Link
US (1) US4382925A (sv)
JP (1) JPS5695198A (sv)
BE (1) BE885415A (sv)
CA (1) CA1173438A (sv)
CH (1) CH647245A5 (sv)
DE (1) DE3036131A1 (sv)
FR (1) FR2466472A1 (sv)
GB (1) GB2060604B (sv)
IT (1) IT1209758B (sv)
NL (1) NL8005336A (sv)
SE (1) SE445740B (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ199764A (en) * 1981-03-20 1984-08-24 Beecham Group Plc 5-(2-halogenovinyl)-2'-deoxyuridine derivatives and pharmaceutical compositions
HU183567B (en) * 1981-09-07 1984-05-28 Mta Koezponti Kemiai Kutato In Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof
JPS5843993A (ja) * 1981-09-09 1983-03-14 Yamasa Shoyu Co Ltd １−β−Ｄ−アラビノフラノシル−（Ｅ）−５−（２−ハロゲノビニル）ウラシル−５′−りん酸およびその製造法
EP0080305A1 (en) * 1981-11-19 1983-06-01 Beecham Group Plc Antiviral 2'-deoxyuridines, their preparation and use
EP0082668A1 (en) * 1981-12-18 1983-06-29 Beecham Group Plc 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections
US4782142A (en) * 1982-01-05 1988-11-01 The Research Foundation Of State University Of New York Novel 5-substituted 2-pyrimidinone nucleosides and methods of use
FR2531962B1 (fr) * 1982-08-17 1986-11-14 Sandoz Sa Nouveaux derives de la desoxyuridine, leur preparation et leur utilisation comme medicaments
CA1257595A (en) * 1982-09-17 1989-07-18 Glaxo Group Ltd 5-HALOGEROVINYL-2'-DESOXYURIDINE DERIVATIVES
HU198393B (en) * 1984-03-06 1989-10-30 Sloan Kettering Inst Cancer Process for production of medical composition suitable for treatment of hepatitis containing as active substance derivatives of piramidin-nucleoside
US4666892A (en) * 1984-03-06 1987-05-19 Sloan-Kettering Memorial Cancer Center Method and composition for hepatitis treatment with pyrimidine nucleoside compounds
US4762823A (en) * 1985-10-16 1988-08-09 Sloan-Kettering Institute For Cancer Research Nucleosides of 5-monofluoromethyluracil and 5-difluoromethyluracil
US5215971A (en) * 1986-12-19 1993-06-01 Medivir Ab Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
SE8605503D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel medicinal use
EP0428623A4 (en) * 1988-08-10 1993-12-08 Stephen Leslie Sacks Production of radioiodinated 1--g(b)-d-arabinofuranosyl)-5(e)-(2-iodovinyl)uracil, and uses thereof, and related analogues incorporating alternative halogen radionuclides, the general radiohalogenation precursors, 1-(2,3,5-tri-o-acetyl--g(b)-d-arabinofuranosyl)-5(z and e)-(2-trimethylsilylvinyl)urac
DK1284720T3 (da) 2000-03-29 2007-01-15 Univ Georgetown L-FMAU til behandling af hepatitis delta-virusinfektion
WO2003053360A2 (en) * 2001-12-20 2003-07-03 Pharmassett Ltd. Treatment of ebv and khsv infection and associated abnormal cellular proliferation
JP2008174524A (ja) * 2007-01-22 2008-07-31 Nippon Shinyaku Co Ltd リボ核酸化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354160A (en) * 1965-07-22 1967-11-21 Hoffmann La Roche Tri-lower alkyl-silyl-5-fluoropyrimidines
US4000260A (en) * 1974-08-29 1976-12-28 Research Corporation Anti herpes simplex viral compounds and their synthesis
US4024143A (en) * 1976-03-11 1977-05-17 Pcr, Inc. Silylation of 5-fluoro-6-hydroxy or alkoxy pyrimidine
US4267171A (en) * 1979-07-02 1981-05-12 The Regents Of The University Of California C-5 Substituted cytosine nucleosides

Also Published As

Publication number Publication date
FR2466472A1 (fr) 1981-04-10
JPS5695198A (en) 1981-08-01
JPS637199B2 (sv) 1988-02-15
GB2060604A (en) 1981-05-07
IT8009551A0 (it) 1980-10-02
NL8005336A (nl) 1981-04-07
DE3036131C2 (sv) 1989-07-06
DE3036131A1 (de) 1981-04-16
FR2466472B1 (sv) 1983-12-23
US4382925A (en) 1983-05-10
SE445740B (sv) 1986-07-14
GB2060604B (en) 1983-11-23
CH647245A5 (de) 1985-01-15
BE885415A (nl) 1981-03-26
CA1173438A (en) 1984-08-28
IT1209758B (it) 1989-08-30

Similar Documents

Publication Publication Date Title
SE8006669L (sv) E-5-(halogenovinyl)-2'-deoxicytidiner och sett for framstellning derav
ES2066461T3 (es) Nuevos derivados fosfolipidicos de nucleosidos, su preparacion, asi como su utilizacion como medicamentos antiviricos.
SE7607825L (sv) 2,4-diklor-4'-bensoylureido-difenyletrar till anvendning som insekticider och sett for deras framstellning
DE69119074D1 (de) Kovalente-ther lipidnukleosid-konjugate
ES2118069T3 (es) Profarmacos de fosfonatos.
AR218822A1 (es) Drenajes de succion para fines medicos
BE883096A (fr) Procede de preparation de concentres de complexe prothrombinique hautement purifies, concentres obtenus et leur application
SE7802378L (sv) Tetrahydrofuraneter-derivat till anvendning som herbicider och sett att framstella foreningarna
SE7804116L (sv) Forbettrat levande newcastlesjukdomsvirusvaccin
FR2422334A1 (sv)
FR2433540A1 (fr) Nouveaux derives de chlorambucil, conjugues de chlorambucil et d'oestradiol, leur procede de preparation et leur application en therapeutique
FI900646A0 (fi) Foerfarande foer framstaellning av fenylhydrazoner och ur dessa erhaollna laekemedel och kosmetiska aemnen.
DE69530857D1 (de) Therapeutische quassinoid-zubereitungen mit antineoplastischer, antiviraler und herbistatischer wirkung
GB1512910A (en) Carbamate-sulphenyl-carbomoyl fluoride compounds
ES2194320T3 (es) Sustancias naturales antivirales o antitumorales y uso de las mismas.
FR2368489A1 (fr) Derives de la clavuline, leur procede de preparation et leur application en therapeutique
FR2416228A1 (fr) Sulfures de 4-pyrimidyle, leur procede de preparation et leur application en therapeutique
IT1094010B (it) Procedimento per la preparazione di 2-aperta far.tonda 2',2',2'-trialogeno-etil chiusa par. tonda-4-alogeno-ciclobutani-1-oni
EP0068033A4 (en) N- (4-PHENYL-2-THIAZOLYL) CARBAMATE DERIVATIVES, PREPARATION METHOD AND MEDICINAL COMPOSITION CONTAINING THEM.
DE59106398D1 (de) Oligophosphate mit antiviraler Wirkung.
IT7820920A0 (it) Esteri oppure esteri amidi pirimidinil(tion)-(tiol)-fosforici(fosfonici)carbomoil ossi sostituiti, procedimenti per laloro preparazione e loro impiegocome insetticidi e come acaricidi.
FR2383178A1 (fr) Aryl-2 (o-(diisopropylamino)alkyl)-2 o-(azabicycloalkyl)alcanamides, leur preparation et leur utilisation therapeutique comme anti-arythmiques
IT7820919A0 (it) Esteri trifluorometil-solfenil-fenil-tion(tiol)-fosforici, procedimento per la loro preparazione e loro impiego come insetticidi, acaricidi e nematocidi.
JPS5384100A (en) Preparation of photo-plymerizable silicone compound
FR2391206A1 (fr) Derives de corioline et leur procede de preparation

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8006669-9

Effective date: 19900703

Format of ref document f/p: F