FR2445829A2 - Methoxy-2 benzamides et leur application en therapeutique - Google Patents

Methoxy-2 benzamides et leur application en therapeutique

Info

Publication number
FR2445829A2
FR2445829A2 FR7900259A FR7900259A FR2445829A2 FR 2445829 A2 FR2445829 A2 FR 2445829A2 FR 7900259 A FR7900259 A FR 7900259A FR 7900259 A FR7900259 A FR 7900259A FR 2445829 A2 FR2445829 A2 FR 2445829A2
Authority
FR
France
Prior art keywords
benzamides
methoxy
therapeutic application
therapeutic
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7900259A
Other languages
English (en)
French (fr)
Other versions
FR2445829B2 (xx
Inventor
Henry Najer
Jean-Pierre Kaplan
Daniel Charles Leon Obitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7805579A external-priority patent/FR2418225A1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7900259A priority Critical patent/FR2445829A2/fr
Priority to IT20541/79A priority patent/IT1113417B/it
Priority to NZ189770A priority patent/NZ189770A/xx
Priority to NO790647A priority patent/NO790647L/no
Priority to ES478072A priority patent/ES478072A1/es
Priority to JP2247779A priority patent/JPS54135765A/ja
Priority to NL7901473A priority patent/NL7901473A/xx
Priority to DK82179A priority patent/DK82179A/da
Priority to AU44603/79A priority patent/AU521027B2/en
Priority to SE7901707A priority patent/SE7901707L/xx
Priority to PT69289A priority patent/PT69289A/pt
Priority to DE19792907378 priority patent/DE2907378A1/de
Priority to IL56738A priority patent/IL56738A0/xx
Priority to GB7906952A priority patent/GB2016467A/en
Priority to LU80975A priority patent/LU80975A1/fr
Priority to GR58491A priority patent/GR66972B/el
Priority to BE0/193729A priority patent/BE874489A/xx
Priority to FI790657A priority patent/FI790657A/fi
Publication of FR2445829A2 publication Critical patent/FR2445829A2/fr
Publication of FR2445829B2 publication Critical patent/FR2445829B2/fr
Application granted granted Critical
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FR7900259A 1978-02-27 1979-01-05 Methoxy-2 benzamides et leur application en therapeutique Granted FR2445829A2 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR7900259A FR2445829A2 (fr) 1978-02-27 1979-01-05 Methoxy-2 benzamides et leur application en therapeutique
PT69289A PT69289A (fr) 1978-02-27 1979-02-26 Procede de preparation de methoxy-2 benzamides
IL56738A IL56738A0 (en) 1978-02-27 1979-02-26 2-methoxybenzamides,their preparation and pharmaceutical composition containing them
NO790647A NO790647L (no) 1978-02-27 1979-02-26 Fremgangsmaate for fremstilling av 2-metoksybenzamider
ES478072A ES478072A1 (es) 1978-02-27 1979-02-26 Un procedimiento de preparacion de 2-metoxi-benzamidas.
JP2247779A JPS54135765A (en) 1978-02-27 1979-02-26 22methoxybenzamide derivative*its manufacture and medicine containing said derivative
NL7901473A NL7901473A (nl) 1978-02-27 1979-02-26 Werkwijze voor de bereiding van een geneesmiddel met een activiteit ten aanzien van het centrale zenuwstel- sel en het aldus gevormde geneesmiddel.
DK82179A DK82179A (da) 1978-02-27 1979-02-26 2-methoxybenzamider og fremgangsmaade til deres fremstilling
AU44603/79A AU521027B2 (en) 1978-02-27 1979-02-26 "2-methoxybenzamides"
SE7901707A SE7901707L (sv) 1978-02-27 1979-02-26 2-betoxibensamider
IT20541/79A IT1113417B (it) 1978-02-27 1979-02-26 2-metossibenzamidi
DE19792907378 DE2907378A1 (de) 1978-02-27 1979-02-26 2-methoxy-benzamide, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
NZ189770A NZ189770A (en) 1978-02-27 1979-02-26 2-methoxybenzamide derivatives and pharmaceutical compositions
GB7906952A GB2016467A (en) 1978-02-27 1979-02-27 2-Methoxybenzamides
LU80975A LU80975A1 (fr) 1978-02-27 1979-02-27 Methoxy-2 benzamides
GR58491A GR66972B (xx) 1978-02-27 1979-02-27
BE0/193729A BE874489A (fr) 1978-02-27 1979-02-27 Methoxy-2 benzamides
FI790657A FI790657A (fi) 1978-02-27 1979-02-27 2-metoxibensamider och foerfarande foer deras framstaellning

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7805579A FR2418225A1 (fr) 1978-02-27 1978-02-27 Methoxy-2 benzamides et leur application en therapeutique
FR7900259A FR2445829A2 (fr) 1978-02-27 1979-01-05 Methoxy-2 benzamides et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2445829A2 true FR2445829A2 (fr) 1980-08-01
FR2445829B2 FR2445829B2 (xx) 1982-09-10

Family

ID=26220462

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7900259A Granted FR2445829A2 (fr) 1978-02-27 1979-01-05 Methoxy-2 benzamides et leur application en therapeutique

Country Status (18)

Country Link
JP (1) JPS54135765A (xx)
AU (1) AU521027B2 (xx)
BE (1) BE874489A (xx)
DE (1) DE2907378A1 (xx)
DK (1) DK82179A (xx)
ES (1) ES478072A1 (xx)
FI (1) FI790657A (xx)
FR (1) FR2445829A2 (xx)
GB (1) GB2016467A (xx)
GR (1) GR66972B (xx)
IL (1) IL56738A0 (xx)
IT (1) IT1113417B (xx)
LU (1) LU80975A1 (xx)
NL (1) NL7901473A (xx)
NO (1) NO790647L (xx)
NZ (1) NZ189770A (xx)
PT (1) PT69289A (xx)
SE (1) SE7901707L (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0320630A1 (en) * 1987-11-19 1989-06-21 The Vanderbilt University Enantiometric iodobenzamides

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2189062A1 (en) * 1972-06-23 1974-01-25 Delmar Chem Substd pyrollidine and piperidines - from 2-alkoxybenzoic acids and amino-(alkyl) pyrrolidines
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
JPS52106863A (en) * 1976-03-03 1977-09-07 Teikoku Hormone Mfg Co Ltd Synthesis of substituted benzamides
FR2360572A1 (fr) * 1976-08-05 1978-03-03 Synthelabo Pyrrolidines substituees et leur preparation
JPS5365875A (en) * 1976-11-24 1978-06-12 Teijin Ltd Preparation of benzenesulfone amide derivs.
FR2393794A2 (fr) * 1977-06-06 1979-01-05 Synthelabo Preparation de methoxy-2 benzamides

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2189062A1 (en) * 1972-06-23 1974-01-25 Delmar Chem Substd pyrollidine and piperidines - from 2-alkoxybenzoic acids and amino-(alkyl) pyrrolidines
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
JPS52106863A (en) * 1976-03-03 1977-09-07 Teikoku Hormone Mfg Co Ltd Synthesis of substituted benzamides
FR2360572A1 (fr) * 1976-08-05 1978-03-03 Synthelabo Pyrrolidines substituees et leur preparation
JPS5365875A (en) * 1976-11-24 1978-06-12 Teijin Ltd Preparation of benzenesulfone amide derivs.
FR2393794A2 (fr) * 1977-06-06 1979-01-05 Synthelabo Preparation de methoxy-2 benzamides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1978 *

Also Published As

Publication number Publication date
IL56738A0 (en) 1979-05-31
BE874489A (fr) 1979-08-27
LU80975A1 (fr) 1980-09-24
FR2445829B2 (xx) 1982-09-10
ES478072A1 (es) 1979-07-01
GB2016467A (en) 1979-09-26
SE7901707L (sv) 1979-08-28
DE2907378A1 (de) 1979-09-06
AU521027B2 (en) 1982-03-11
NL7901473A (nl) 1979-08-29
IT7920541A0 (it) 1979-02-26
JPS54135765A (en) 1979-10-22
IT1113417B (it) 1986-01-20
FI790657A (fi) 1979-08-28
GR66972B (xx) 1981-05-15
DK82179A (da) 1979-08-28
NO790647L (no) 1979-08-28
PT69289A (fr) 1979-03-01
NZ189770A (en) 1980-11-14
AU4460379A (en) 1979-09-06

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