ES478072A1 - Un procedimiento de preparacion de 2-metoxi-benzamidas. - Google Patents

Un procedimiento de preparacion de 2-metoxi-benzamidas.

Info

Publication number
ES478072A1
ES478072A1 ES478072A ES478072A ES478072A1 ES 478072 A1 ES478072 A1 ES 478072A1 ES 478072 A ES478072 A ES 478072A ES 478072 A ES478072 A ES 478072A ES 478072 A1 ES478072 A1 ES 478072A1
Authority
ES
Spain
Prior art keywords
radical
alkyl
methoxybenzamides
so2nr1r2
racemates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES478072A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7805579A external-priority patent/FR2418225A1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES478072A1 publication Critical patent/ES478072A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Un procedimiento de preparación de 2-metoxi-benzamidas, en forma de racematos o de enantiómeros, que responden a la fórmula (I) **(Fórmula)** en la que n es 1, 2, 3 ó 4; R es o bien un radical SO2NR1R2, en el que R1 y R2 representan, independientemente uno del otro, un átomo de hidrógeno o un alcohilo, o bien un radical S(O)mR3, en el que R3 es un alcohilo y m es 0, 1 ó 2, o bien un átomo de halógeno, o bien el radical CF3, teniendo los alcohilos de 1 a 4 átomos de carbono, así como sus sales de adición con ácidos farmacéuticamente aceptables.
ES478072A 1978-02-27 1979-02-26 Un procedimiento de preparacion de 2-metoxi-benzamidas. Expired ES478072A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7805579A FR2418225A1 (fr) 1978-02-27 1978-02-27 Methoxy-2 benzamides et leur application en therapeutique
FR7900259A FR2445829A2 (fr) 1978-02-27 1979-01-05 Methoxy-2 benzamides et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES478072A1 true ES478072A1 (es) 1979-07-01

Family

ID=26220462

Family Applications (1)

Application Number Title Priority Date Filing Date
ES478072A Expired ES478072A1 (es) 1978-02-27 1979-02-26 Un procedimiento de preparacion de 2-metoxi-benzamidas.

Country Status (18)

Country Link
JP (1) JPS54135765A (es)
AU (1) AU521027B2 (es)
BE (1) BE874489A (es)
DE (1) DE2907378A1 (es)
DK (1) DK82179A (es)
ES (1) ES478072A1 (es)
FI (1) FI790657A (es)
FR (1) FR2445829A2 (es)
GB (1) GB2016467A (es)
GR (1) GR66972B (es)
IL (1) IL56738A0 (es)
IT (1) IT1113417B (es)
LU (1) LU80975A1 (es)
NL (1) NL7901473A (es)
NO (1) NO790647L (es)
NZ (1) NZ189770A (es)
PT (1) PT69289A (es)
SE (1) SE7901707L (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0320630A1 (en) * 1987-11-19 1989-06-21 The Vanderbilt University Enantiometric iodobenzamides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH584688A5 (es) * 1972-06-23 1977-02-15 Delmar Chem
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
FR2393794A2 (fr) * 1977-06-06 1979-01-05 Synthelabo Preparation de methoxy-2 benzamides
JPS52106863A (en) * 1976-03-03 1977-09-07 Teikoku Hormone Mfg Co Ltd Synthesis of substituted benzamides
FR2360572A1 (fr) * 1976-08-05 1978-03-03 Synthelabo Pyrrolidines substituees et leur preparation
JPS5365875A (en) * 1976-11-24 1978-06-12 Teijin Ltd Preparation of benzenesulfone amide derivs.

Also Published As

Publication number Publication date
AU4460379A (en) 1979-09-06
DK82179A (da) 1979-08-28
AU521027B2 (en) 1982-03-11
FR2445829A2 (fr) 1980-08-01
GB2016467A (en) 1979-09-26
IT1113417B (it) 1986-01-20
NL7901473A (nl) 1979-08-29
GR66972B (es) 1981-05-15
SE7901707L (sv) 1979-08-28
JPS54135765A (en) 1979-10-22
IT7920541A0 (it) 1979-02-26
IL56738A0 (en) 1979-05-31
LU80975A1 (fr) 1980-09-24
DE2907378A1 (de) 1979-09-06
NZ189770A (en) 1980-11-14
FI790657A (fi) 1979-08-28
PT69289A (fr) 1979-03-01
FR2445829B2 (es) 1982-09-10
NO790647L (no) 1979-08-28
BE874489A (fr) 1979-08-27

Similar Documents

Publication Publication Date Title
ES477457A1 (es) Procedimiento de preparacion de amidas de alcohilendiaminas.
DE3363244D1 (en) Compounds, process for their preparation and their use as pharmaceutical preparations
ES443725A1 (es) Metodo para producir un producto hipotensor.
ZA911403B (en) Derivatives having a naphthalene structure,process for preparing these and pharmaceutical compositions containing them
MY100095A (en) 2-oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition.
ES482889A1 (es) Procedimiento de preparacion de derivados de fluorenos y fluorantenos
ES8504777A1 (es) Un procedimiento para la preparacion de derivados de fenilpiperazina
ES478072A1 (es) Un procedimiento de preparacion de 2-metoxi-benzamidas.
ES2012559A6 (es) Nuevos isopolipeptidos y procedimiento para su preparacion.
ES478073A1 (es) Un procedimiento de preparacion de benzamidas.
ES475299A1 (es) Procedimiento para preparar derivados del naftaleno.
HUT39158A (en) Process for preparing carbacyclines and pharmaceutical compositions containing such compounds
ES8302695A1 (es) Procedimiento para la obtencion de nuevos compuestos de poliglicidilurazol n.substituidos.
DE3362248D1 (en) Ergoline derivatives, process for producing the ergoline derivatives and pharmaceutical compositions containing them
ES479537A1 (es) Procedimiento de preparacion de esteres bencilidenicos.
SE8204791D0 (sv) Process for preparing alkoxy-vincaminic acid esters and alkoxy-apovincaminic acid esters
ES465366A2 (es) Un procedimiento de preparacion de derivados de metoxi-2- benzamidas.
ES8505656A1 (es) Procedimiento para la preparacion de quinolinonas-4
ES485333A1 (es) Procedimiento para preparar derivados 5,6,7,8-tetrahidro-4 (3h)-quinazolinonicos y sus sales
ES8504193A1 (es) Un procedimiento de preparacion de hexahidro-indolo-naftiridinas
AU560032B2 (en) Derivatives of r-butyrolactone
AT383599B (de) Verfahren zur herstellung von neuen racemischen und optisch aktiven e-homo-eburnan-derivaten sowievon saeureadditions-salzen derselben
ES275615A1 (es) Procedimiento para la preparación de un nuevo derivado de la piperacina
ES483300A1 (es) Un procedimiento para la preparacion de derivados de benzo- diacepina