ES482889A1 - Procedimiento de preparacion de derivados de fluorenos y fluorantenos - Google Patents

Procedimiento de preparacion de derivados de fluorenos y fluorantenos

Info

Publication number
ES482889A1
ES482889A1 ES482889A ES482889A ES482889A1 ES 482889 A1 ES482889 A1 ES 482889A1 ES 482889 A ES482889 A ES 482889A ES 482889 A ES482889 A ES 482889A ES 482889 A1 ES482889 A1 ES 482889A1
Authority
ES
Spain
Prior art keywords
alkyl
radical
hydrogen atom
fluorene
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES482889A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7822353A external-priority patent/FR2432026A1/fr
Priority claimed from FR7822352A external-priority patent/FR2432025A1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES482889A1 publication Critical patent/ES482889A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Procedimiento de preparación de derivados de fluorenos y fluorantenos, en la forma de racematos o de enantiómeros, que responden a la fórmula (I). **(Fórmula)** en la que n es 1 ó 2, R1 es un átomo de hidrógeno o de halógeno o un radical alcohilo o alcoxi, R2 es un átomo de hidrógeno, un radical alcohilo, cicloalcohilo, cicloalcohilalcohilo, bencilo, halogeno-bencilo, alcohil-bencilo, alcoxi-bencilo, acilo, alcoxicarbonilo, o alcohil- aminocarbonilo, R3 es un átomo de hidrógeno o un radical alcohilo, R4 es un átomo de hidrógeno, un radical alcohilo, acilo o aroílo, teniendo los radicales alcohilo y alcoxi de 1 a 4 átomos de carbono.
ES482889A 1978-07-28 1979-07-27 Procedimiento de preparacion de derivados de fluorenos y fluorantenos Expired ES482889A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7822353A FR2432026A1 (fr) 1978-07-28 1978-07-28 Derives de fluorenes et de fluoranthenes et leur application en therapeutique
FR7822352A FR2432025A1 (fr) 1978-07-28 1978-07-28 Derives d'imidazo et de pyrimido-pyrido-indoles, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES482889A1 true ES482889A1 (es) 1980-04-16

Family

ID=26220699

Family Applications (1)

Application Number Title Priority Date Filing Date
ES482889A Expired ES482889A1 (es) 1978-07-28 1979-07-27 Procedimiento de preparacion de derivados de fluorenos y fluorantenos

Country Status (13)

Country Link
US (1) US4277476A (es)
EP (1) EP0008249B1 (es)
AT (1) ATE165T1 (es)
AU (1) AU524307B2 (es)
CA (1) CA1107729A (es)
DE (1) DE2960689D1 (es)
DK (1) DK316279A (es)
ES (1) ES482889A1 (es)
FI (1) FI65250C (es)
GR (1) GR75070B (es)
NO (1) NO792476L (es)
NZ (1) NZ191141A (es)
PT (1) PT69988A (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2455044A1 (fr) * 1979-04-26 1980-11-21 Synthelabo Pyrido-indoles et leur application en therapeutique
US4367230A (en) * 1980-01-04 1983-01-04 Tanabe Seiyaku Co., Ltd. Novel triazafluoranthene compound and processes for preparing the same
GB2184685B (en) * 1985-12-19 1989-10-11 Braas & Co Gmbh Plastically deformable sheet material
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN102408425A (zh) 2004-03-15 2012-04-11 Ptc医疗公司 用于抑制血管生成的咔啉衍生物及其应用
US7767689B2 (en) 2004-03-15 2010-08-03 Ptc Therapeutics, Inc. Carboline derivatives useful in the treatment of cancer
US8076352B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Administration of carboline derivatives useful in the treatment of cancer and other diseases
US8076353B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Inhibition of VEGF translation
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2556574A (en) * 1949-06-24 1951-06-12 Allen & Hanburys Ltd Indolopteridines and process for preparing same
US3108108A (en) * 1959-09-25 1963-10-22 Bayer Ag Aza analogues of polynuclear o-quinones
US3122544A (en) * 1962-11-13 1964-02-25 American Home Prod 4-amino-2-aryl-6h-indeno(2, 3-g)-pteridin-6-ones
US3470181A (en) * 1967-10-23 1969-09-30 American Home Prod Fused 2-pyrimidinepropionic acid compounds,related compounds,and the process for their preparation
US3631046A (en) * 1969-05-28 1971-12-28 Sandoz Ag Tetracyclic quinazolin-ones
BE759337A (fr) * 1969-11-24 1971-05-24 Lilly Co Eli Benzimidazol (2,1-b)-quinazolin (6h) ones qui sont des immuno-depresseurs, et nouvelles benzimidazo (2,1-b) quinazolin-12-(6h) ones
US3963720A (en) * 1972-10-27 1976-06-15 Sandoz, Inc. Tetracyclic imidazo [2,1-b] quinazolinone derivatives
CH601299A5 (en) * 1973-11-07 1978-07-14 Vni Khim Farmatsevtichesky I I Pyrazino(1,2,3-ab)beta carbolines and homologues

Also Published As

Publication number Publication date
AU4927879A (en) 1980-01-31
NO792476L (no) 1980-01-29
FI792366A (fi) 1980-01-29
EP0008249A3 (en) 1980-05-14
US4277476A (en) 1981-07-07
EP0008249A2 (fr) 1980-02-20
DE2960689D1 (en) 1981-11-19
CA1107729A (en) 1981-08-25
ATE165T1 (de) 1981-09-15
FI65250B (fi) 1983-12-30
PT69988A (fr) 1979-08-01
DK316279A (da) 1980-01-29
GR75070B (es) 1984-07-13
AU524307B2 (en) 1982-09-09
NZ191141A (en) 1983-02-15
FI65250C (fi) 1984-04-10
EP0008249B1 (fr) 1981-08-26

Similar Documents

Publication Publication Date Title
ES482889A1 (es) Procedimiento de preparacion de derivados de fluorenos y fluorantenos
HU913396D0 (en) Process for the production of azasteroide compounds and medical preparations containing them as active agents
DE3271269D1 (en) Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same
HUT44001A (en) Process for producing new phenoxy-acetamide derivatives and pharmaceutical compositions containing them as active components
ES8306373A1 (es) "procedimiento para la preparacion de 9-(2-(3-indolil)-etil)-1-oxa-4,9-diazaspiro (5.5) undecan-3-onas".
ES8203845A1 (es) Procedimiento para preparar derivados de piridoxina
ES8503667A1 (es) Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina.
MY111702A (en) 5-amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative
ZA816259B (en) 2-(1,4-benzodioxan-2-ylalkyl)imidazoles useful as antidepressants
ZA888853B (en) N-(23-vinblastinoyl)derivatives of 1-aminomethylphosphonic acid,process for preparing them and pharmaceutical compositions containing them
NO823125L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 2-amino-naftalen-derivater
ES435361A1 (es) Un metodo para la preparacion de nuevos esteres alcohilicosde aminoacidos.
ES8302695A1 (es) Procedimiento para la obtencion de nuevos compuestos de poliglicidilurazol n.substituidos.
ES478072A1 (es) Un procedimiento de preparacion de 2-metoxi-benzamidas.
SE8302452D0 (sv) Method for treatment of senile dementia
SE8204791D0 (sv) Process for preparing alkoxy-vincaminic acid esters and alkoxy-apovincaminic acid esters
ES2018404A6 (es) Procedimiento para preparar nuevas 2-metoxicarbonil sustituido-n, n'-di-(trimetoxibenzoil)-piperazinas.
JPS568400A (en) Novel 122dehydrodigoxinnoxime* its manufacture and heart failure drug containing same
DE3262706D1 (en) Oximes of 3"'-dehydro-cardenolide-tridigitoxosides, process for their preparation and their use as medicaments
ES8104198A1 (es) Un procedimiento para la preparacion de un derivado de mo- noamida del acido tereftalico
GB2014995A (en) (Cycloalkyl)-alkylbenzamides
ES478502A1 (es) Un procedimiento para la preparacion de nuevas n-(piridotie-nopirazol)amidas
GB1072167A (en) Improvements in or relating to oxa-1-azabicycloalkane derivatives