ES478502A1 - Un procedimiento para la preparacion de nuevas n-(piridotie-nopirazol)amidas - Google Patents

Un procedimiento para la preparacion de nuevas n-(piridotie-nopirazol)amidas

Info

Publication number
ES478502A1
ES478502A1 ES478502A ES478502A ES478502A1 ES 478502 A1 ES478502 A1 ES 478502A1 ES 478502 A ES478502 A ES 478502A ES 478502 A ES478502 A ES 478502A ES 478502 A1 ES478502 A1 ES 478502A1
Authority
ES
Spain
Prior art keywords
pyridothienopyrazol
amides
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES478502A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/970,732 external-priority patent/US4220776A/en
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of ES478502A1 publication Critical patent/ES478502A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Un procedimiento para la preparación de nuevas N-(piridotienopirazol) amidas, de fórmula: **(Formula-01)** donde R1 es metilo o etilo; R2 está seleccionado entre ciclohexilo, bencilo, 3-piridilo, 1-adamantilo, haloalquilo C2-5 con 1 a 3 sustituyentes halógeno en una posición distinta de la posición alfa con respecto al grupo carbonilo y los grupos **(Formula-02)** X es H, C1 o F; R3 y R4 están seleccionados independientemente entre H y alquilo C1-3 y R5 está seleccionado entre H y alquilo C1-5; y sales de adición de ácidos farmacéuticamente aceptables.
ES478502A 1978-03-10 1979-03-09 Un procedimiento para la preparacion de nuevas n-(piridotie-nopirazol)amidas Expired ES478502A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88525278A 1978-03-10 1978-03-10
US05/970,732 US4220776A (en) 1978-12-21 1978-12-21 N-(Pyridothienopyrazol)amides

Publications (1)

Publication Number Publication Date
ES478502A1 true ES478502A1 (es) 1980-07-01

Family

ID=27128754

Family Applications (1)

Application Number Title Priority Date Filing Date
ES478502A Expired ES478502A1 (es) 1978-03-10 1979-03-09 Un procedimiento para la preparacion de nuevas n-(piridotie-nopirazol)amidas

Country Status (18)

Country Link
EP (1) EP0004319B1 (es)
JP (1) JPS54145698A (es)
AR (1) AR221612A1 (es)
AT (1) AT369370B (es)
AU (1) AU522953B2 (es)
CA (1) CA1114372A (es)
DE (1) DE2960549D1 (es)
DK (1) DK28979A (es)
ES (1) ES478502A1 (es)
FI (1) FI790818A (es)
GR (1) GR66657B (es)
HU (1) HU179006B (es)
IL (1) IL56828A (es)
NO (1) NO790778L (es)
NZ (1) NZ189870A (es)
PH (1) PH14896A (es)
PT (1) PT69319A (es)
SU (1) SU745368A3 (es)

Also Published As

Publication number Publication date
DK28979A (da) 1979-09-11
HU179006B (en) 1982-08-28
EP0004319B1 (en) 1981-08-05
AT369370B (de) 1982-12-27
EP0004319A1 (en) 1979-10-03
AU4488179A (en) 1979-09-13
IL56828A (en) 1981-12-31
SU745368A3 (ru) 1980-06-30
GR66657B (es) 1981-04-07
ATA179679A (de) 1982-05-15
DE2960549D1 (en) 1981-11-05
FI790818A (fi) 1979-09-11
NZ189870A (en) 1981-07-13
NO790778L (no) 1979-09-11
JPS54145698A (en) 1979-11-14
CA1114372A (en) 1981-12-15
IL56828A0 (en) 1979-05-31
PT69319A (en) 1979-04-01
PH14896A (en) 1982-01-08
AR221612A1 (es) 1981-02-27
AU522953B2 (en) 1982-07-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19841024