FR2445141A1 - Suppositoires contenant le demi fumarate monohydrate d'alcool formylamino-3-hydroxy-4-a -(n-(methyl-1-p-methoxyphenyl-2-ethyl)aminomethyl)-benzylique presentant une activite bronchodilatatrice - Google Patents
Suppositoires contenant le demi fumarate monohydrate d'alcool formylamino-3-hydroxy-4-a -(n-(methyl-1-p-methoxyphenyl-2-ethyl)aminomethyl)-benzylique presentant une activite bronchodilatatriceInfo
- Publication number
- FR2445141A1 FR2445141A1 FR7930823A FR7930823A FR2445141A1 FR 2445141 A1 FR2445141 A1 FR 2445141A1 FR 7930823 A FR7930823 A FR 7930823A FR 7930823 A FR7930823 A FR 7930823A FR 2445141 A1 FR2445141 A1 FR 2445141A1
- Authority
- FR
- France
- Prior art keywords
- formylamino
- methoxyphenyl
- hydroxy
- methyl
- benzylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 ALUMINUM FUMARATE MONOHYDRATE Chemical compound 0.000 title abstract 3
- 239000000829 suppository Substances 0.000 title abstract 3
- OBRNDARFFFHCGE-PERKLWIXSA-N (S,S)-formoterol fumarate Chemical compound OC(=O)\C=C\C(O)=O.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1 OBRNDARFFFHCGE-PERKLWIXSA-N 0.000 abstract 2
- HAFWELDDNUXLCK-TYYBGVCCSA-N (e)-but-2-enedioic acid;hydrate Chemical compound O.OC(=O)\C=C\C(O)=O HAFWELDDNUXLCK-TYYBGVCCSA-N 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- WVDDGKGOMKODPV-UHFFFAOYSA-N benzyl alcohol Substances OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000004682 monohydrates Chemical class 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002511 suppository base Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/15—Suppositories
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La présente invention concerne un suppositoire à base de demi fumarate monohydraté d'alcool formylamino-3-hydroxy-4- alpha -ØN-(méthyl-1-p-méthoxyphényl-2-éthyl)aminométhylõ-benzylique BD-40A. Conformément à l'invention le demi fumarate monohydraté d'alcool formylamino-3-hydroxy-4- alpha -ØN-(méthyl-1-p-méthoxyphényl-2-éthylaminométhylõ-benzylique BD-40A est mis en composition avec de la polivinylpyrrolidone et au moins un des composés du groupe constitué par la cyclodextrine, le dextrane et le métasilicate-aluminate de magnésium ensemble avec une base pour suppositoire. L'invention permet d'obtenir un suppositoire stable.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16542678A JPS5592312A (en) | 1978-12-29 | 1978-12-29 | Suppository containing bronchodilating compound |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2445141A1 true FR2445141A1 (fr) | 1980-07-25 |
FR2445141B1 FR2445141B1 (fr) | 1983-06-17 |
Family
ID=15812191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7930823A Granted FR2445141A1 (fr) | 1978-12-29 | 1979-12-17 | Suppositoires contenant le demi fumarate monohydrate d'alcool formylamino-3-hydroxy-4-a -(n-(methyl-1-p-methoxyphenyl-2-ethyl)aminomethyl)-benzylique presentant une activite bronchodilatatrice |
Country Status (9)
Country | Link |
---|---|
US (1) | US4268501A (fr) |
JP (1) | JPS5592312A (fr) |
CH (1) | CH645805A5 (fr) |
DE (1) | DE2951077A1 (fr) |
DK (1) | DK155914C (fr) |
ES (1) | ES487380A0 (fr) |
FR (1) | FR2445141A1 (fr) |
GB (1) | GB2038180B (fr) |
IT (1) | IT1192790B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2496460A1 (fr) * | 1980-12-19 | 1982-06-25 | Chinoin Gyogyszer Es Vegyeszet | Suppositoires stables malgre un composant actif volatil et/ou decomposable et procede pour leur preparation |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1131833B (it) * | 1980-06-20 | 1986-06-25 | Crinos Industria Farmaco | Eccipienti per sostanze spermicide |
JPS5921613A (ja) * | 1982-07-28 | 1984-02-03 | Takeda Chem Ind Ltd | 直腸投与製剤 |
US4518583A (en) * | 1983-02-22 | 1985-05-21 | Gallina Damian J | Hemorrhoid and anorectal disease treatment method |
US4514384A (en) * | 1983-03-14 | 1985-04-30 | Gallina Damian J | Hemorrhoid treatment method |
PH25150A (en) * | 1986-06-05 | 1991-03-13 | Ciba Geigy Ag | Novel pharmaceutical preparation for topical application |
US6287603B1 (en) | 1999-09-16 | 2001-09-11 | Nestec S.A. | Cyclodextrin flavor delivery systems |
KR20080023682A (ko) * | 2005-06-13 | 2008-03-14 | 카아길, 인코포레이팃드 | 시클로덱스트린 포접 착물 및 그의 제조 방법 |
JP2008546386A (ja) * | 2005-06-13 | 2008-12-25 | カーギル インコーポレイテッド | シクロデキストリン包接複合体及びその製造方法 |
RU2009100882A (ru) * | 2006-06-13 | 2010-07-20 | Карджилл, Инкорпорейтед (Us) | Крупные частицы комплексов включения циклодекстринов и способы их получения |
US20100160623A1 (en) * | 2006-12-27 | 2010-06-24 | Cargill, Incorporated | Cyclodextrin inclusion complexes and methods of preparing same |
US20080283693A1 (en) * | 2007-05-15 | 2008-11-20 | Evans Michael J F | Propulsion apparatus and system |
GB2538309B (en) | 2015-05-15 | 2017-09-20 | Dyson Technology Ltd | Cleaning appliance |
GB2555620B (en) | 2016-11-04 | 2019-03-13 | Dyson Technology Ltd | Cleaning appliance |
GB2559380B (en) | 2017-02-03 | 2019-09-25 | Dyson Technology Ltd | Dental treatment appliance |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3234091A (en) * | 1955-07-08 | 1966-02-08 | Ciba Geigy Corp | Shaped medicaments and process for their manufacture |
DE1094930B (de) * | 1959-04-24 | 1960-12-15 | Dehydag Gmbh | Verfahren zur Herstellung von Suppositorien |
US3994974A (en) * | 1972-02-05 | 1976-11-30 | Yamanouchi Pharmaceutical Co., Ltd. | α-Aminomethylbenzyl alcohol derivatives |
DE2553026A1 (de) * | 1974-12-04 | 1976-06-10 | Schlueter Edelfett | Neue formulierungen |
DE2551446B2 (de) * | 1975-11-15 | 1977-09-15 | Karl Werner Schlüter GmbH, 2000 Ham burg | Verfahren zur herstellung von suppositorien |
-
1978
- 1978-12-29 JP JP16542678A patent/JPS5592312A/ja active Granted
-
1979
- 1979-12-05 US US06/101,012 patent/US4268501A/en not_active Expired - Lifetime
- 1979-12-10 IT IT69372/79A patent/IT1192790B/it active
- 1979-12-13 GB GB7942970A patent/GB2038180B/en not_active Expired
- 1979-12-17 FR FR7930823A patent/FR2445141A1/fr active Granted
- 1979-12-19 DK DK542879A patent/DK155914C/da not_active IP Right Cessation
- 1979-12-19 DE DE19792951077 patent/DE2951077A1/de active Granted
- 1979-12-21 CH CH1135979A patent/CH645805A5/de not_active IP Right Cessation
- 1979-12-28 ES ES487380A patent/ES487380A0/es active Granted
Non-Patent Citations (1)
Title |
---|
EXBK/76 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2496460A1 (fr) * | 1980-12-19 | 1982-06-25 | Chinoin Gyogyszer Es Vegyeszet | Suppositoires stables malgre un composant actif volatil et/ou decomposable et procede pour leur preparation |
Also Published As
Publication number | Publication date |
---|---|
ES8100075A1 (es) | 1980-11-01 |
US4268501A (en) | 1981-05-19 |
DK155914C (da) | 1989-10-23 |
CH645805A5 (de) | 1984-10-31 |
DK155914B (da) | 1989-06-05 |
IT1192790B (it) | 1988-05-04 |
DE2951077A1 (de) | 1980-07-10 |
GB2038180B (en) | 1982-12-15 |
IT7969372A0 (it) | 1979-12-10 |
JPS629090B2 (fr) | 1987-02-26 |
FR2445141B1 (fr) | 1983-06-17 |
DE2951077C2 (fr) | 1989-01-12 |
ES487380A0 (es) | 1980-11-01 |
GB2038180A (en) | 1980-07-23 |
DK542879A (da) | 1980-06-30 |
JPS5592312A (en) | 1980-07-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |