FR2424320A1 - Procede de production de cephalosporines par culture de souches ameliorees d'acremonium chrysogenum - Google Patents

Procede de production de cephalosporines par culture de souches ameliorees d'acremonium chrysogenum

Info

Publication number
FR2424320A1
FR2424320A1 FR7910487A FR7910487A FR2424320A1 FR 2424320 A1 FR2424320 A1 FR 2424320A1 FR 7910487 A FR7910487 A FR 7910487A FR 7910487 A FR7910487 A FR 7910487A FR 2424320 A1 FR2424320 A1 FR 2424320A1
Authority
FR
France
Prior art keywords
cephalosporins
culture
improved
production
acremonium chrysogenum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7910487A
Other languages
English (en)
Other versions
FR2424320B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Glaxo Wellcome SA
Glaxo Laboratories Ltd
Original Assignee
Laboratoires Glaxo SA
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Glaxo SA, Glaxo Laboratories Ltd filed Critical Laboratoires Glaxo SA
Publication of FR2424320A1 publication Critical patent/FR2424320A1/fr
Application granted granted Critical
Publication of FR2424320B1 publication Critical patent/FR2424320B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/04—Fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'INVENTION CONCERNE UNE SOUCHE AMELIOREE D'ACREMONIUM CHRYSOGENUM. ON PRODUIT CETTE SOUCHE EN SOUMETTANT DES SOUCHES MERES D'ACREMONIUM CHRYSOGENUM A UNE FUSION PROTOPLASMIQUE ET UNE FUSION NUCLEAIRE ET EN CHOISISSANT LA SOUCHE AMELIOREE PARMI LES DESCENDANTS OU UN DE LEURS MUTANTS. LES SOUCHES EN QUESTION PERMETTENT DE PROCEDER A LA PRODUCTION DE CEPHALOSPORINES GRACE A LEUR CULTURE.
FR7910487A 1978-04-26 1979-04-25 Procede de production de cephalosporines par culture de souches ameliorees d'acremonium chrysogenum Granted FR2424320A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1652878 1978-04-26

Publications (2)

Publication Number Publication Date
FR2424320A1 true FR2424320A1 (fr) 1979-11-23
FR2424320B1 FR2424320B1 (fr) 1984-01-06

Family

ID=10078967

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7910487A Granted FR2424320A1 (fr) 1978-04-26 1979-04-25 Procede de production de cephalosporines par culture de souches ameliorees d'acremonium chrysogenum

Country Status (10)

Country Link
US (1) US4368263A (fr)
JP (1) JPS54163880A (fr)
BE (1) BE875844A (fr)
CH (1) CH645405A5 (fr)
DE (1) DE2916736A1 (fr)
DK (1) DK169879A (fr)
FR (1) FR2424320A1 (fr)
GB (1) GB2021640B (fr)
IT (1) IT1116868B (fr)
NL (1) NL7903251A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0065257A2 (fr) * 1981-05-14 1982-11-24 Hoechst Aktiengesellschaft Procédé d'obtention de souches de moissisures aptes à la production d'antibiotiques
CN112538436A (zh) * 2020-12-23 2021-03-23 江苏三仪生物工程有限公司 一种地顶孢霉培养物的制备方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520101A (en) * 1983-03-07 1985-05-28 Bristol-Myers Company Production of cephalosporin C
US4643901A (en) * 1983-06-10 1987-02-17 Universal Foods Corporation Yeast strains, method of production and use in baking
DE69835360T2 (de) * 1997-01-17 2007-08-16 Maxygen, Inc., Redwood City EVOLUTION Prokaryotischer GANZER ZELLEN DURCH REKURSIVE SEQUENZREKOMBINATION
US7148054B2 (en) * 1997-01-17 2006-12-12 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
EP1026236A1 (fr) * 1999-02-04 2000-08-09 Dsm N.V. Souches auxotrophes pour la biosynthèse de métabolites secondaires
CN105524849B (zh) * 2016-02-01 2019-02-12 中国科学院微生物研究所 一株不依赖于甲硫氨酸的头孢菌素高产基因工程菌株的构建及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2245763A1 (fr) * 1973-09-28 1975-04-25 Takeda Chemical Industries Ltd

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2245763A1 (fr) * 1973-09-28 1975-04-25 Takeda Chemical Industries Ltd

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
CA1971 *
CA1974 *
CA1977 *
CA1978 *
CA1979 *
EXBK/75 *
EXBK/76 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0065257A2 (fr) * 1981-05-14 1982-11-24 Hoechst Aktiengesellschaft Procédé d'obtention de souches de moissisures aptes à la production d'antibiotiques
EP0065257A3 (fr) * 1981-05-14 1983-02-09 Hoechst Aktiengesellschaft Procédé d'obtention de souches de moissisures aptes à la production d'antibiotiques
CN112538436A (zh) * 2020-12-23 2021-03-23 江苏三仪生物工程有限公司 一种地顶孢霉培养物的制备方法

Also Published As

Publication number Publication date
DK169879A (da) 1979-10-27
CH645405A5 (de) 1984-09-28
GB2021640A (en) 1979-12-05
BE875844A (fr) 1979-10-25
FR2424320B1 (fr) 1984-01-06
NL7903251A (nl) 1979-10-30
IT7948848A0 (it) 1979-04-26
JPS54163880A (en) 1979-12-26
JPH0348792B2 (fr) 1991-07-25
GB2021640B (en) 1982-11-03
IT1116868B (it) 1986-02-10
DE2916736A1 (de) 1979-11-08
US4368263A (en) 1983-01-11

Similar Documents

Publication Publication Date Title
FR2424320A1 (fr) Procede de production de cephalosporines par culture de souches ameliorees d'acremonium chrysogenum
Sykes et al. R factors, beta-lactamase, and carbenicillin-resistant Pseudomonas aeruginosa
ES8604648A1 (es) Procedimiento para la fabricacion de un compuesto del acido 7-aminocefalosporanico.
DE3170118D1 (en) Process for the preparation of deacetylcephalosporin c
FR2476085B1 (fr) Composes obtenus par culture de microorganismes appartenant a la souche bacillus et procede pour les obtenir
ES8106760A1 (es) Un procedimiento para la preparacion de desacetil-cefalospo-rina c
FR2457292A1 (fr) Purification de riboflavine
FR2637913B1 (fr) Procede de production de polysaccharides par fermentation d'une source hydrocarbonee a l'aide de microorganismes
CA2014826A1 (fr) Methode de depistage des substances ayant une potentiel eleve d'induction des iga et souches bacteriennes du genre bifidobacterium
BE899661A (fr) Procede d'augmentation de la production d'antibiotique par recombinaison genetique in vivo.
ES444311A1 (es) Un procedimiento de lisis del residuo micelar obtenido en laproduccion de antibioticos.
BE876083A (fr) Procede pour ameliorer la durete d'un agregat de cellules bacteriennes
NO176327C (no) Fremgangsmåte for fremstilling av riboflavin og stammer av Candida famata for anvendelse deri
GB1488822A (en) Production of cephalosporin c
ES475593A1 (es) Procedimiento de obtencion de un producto biologico extraido de un cultivo de hongos.
FR2372166A1 (fr) Procede de preparation d'acide 6-aminopenicillanique par transformation enzymatique d'une penicilline
GB1369970A (en) Process for producing 7-aminodesacetoxy-cephalosporanic acid
FR2445339A1 (fr) Nouvelle substance antibiotique et sa preparation
GB1479174A (en) Process for the preparation of 6-amino-penicillanic acid 1-oxide
GB1378103A (en) Serological reagent and test for neisseria gonorrhoeae antibodies
GB1376573A (en) Process for the production of an amylase inhibitor
MY104917A (en) Monoclonal antibodies and methods for diagnosis of phytophora infection
NO843446L (no) Antibiotikum sb 22484
SU1135192A1 (ru) Способ определения чувствительности животных к мелиоидозу
GB2021119A (en) Penicillin V-acylase

Legal Events

Date Code Title Description
ST Notification of lapse