FR2418235A1 - Procede de preparation d'acides 7-imidazolidinyl substitue 3-chloro-3-cephem-4-carboxyliques et nouveaux produits ainsi obtenus, employes notamment comme agents antibacteriens - Google Patents

Procede de preparation d'acides 7-imidazolidinyl substitue 3-chloro-3-cephem-4-carboxyliques et nouveaux produits ainsi obtenus, employes notamment comme agents antibacteriens

Info

Publication number
FR2418235A1
FR2418235A1 FR7904600A FR7904600A FR2418235A1 FR 2418235 A1 FR2418235 A1 FR 2418235A1 FR 7904600 A FR7904600 A FR 7904600A FR 7904600 A FR7904600 A FR 7904600A FR 2418235 A1 FR2418235 A1 FR 2418235A1
Authority
FR
France
Prior art keywords
cephem
chloro
imidazolidinyl
carboxylic
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7904600A
Other languages
English (en)
Other versions
FR2418235B1 (fr
Inventor
Yoshinobu Ko'oka
Mariko Munekage
Hitoshi Minato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of FR2418235A1 publication Critical patent/FR2418235A1/fr
Application granted granted Critical
Publication of FR2418235B1 publication Critical patent/FR2418235B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/58—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with a nitrogen atom, which is a member of a hetero ring, attached in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procédé de préparation d'acides imidazolidinyl substitué-3-chloro-3-céphem-4-carboxyliques et nouveaux produits ainsi obtenus. Ces acides 7 beta -Ø2-(substitué ou non substitué)-5-oxo-4-phénylimidazolidin-1-ylõ-3-chloro-3-céphem-4-carboxyliques sont représentés par la formule :
FR7904600A 1978-02-23 1979-02-22 Procede de preparation d'acides 7-imidazolidinyl substitue 3-chloro-3-cephem-4-carboxyliques et nouveaux produits ainsi obtenus, employes notamment comme agents antibacteriens Granted FR2418235A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2067578A JPS54112892A (en) 1978-02-23 1978-02-23 Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid

Publications (2)

Publication Number Publication Date
FR2418235A1 true FR2418235A1 (fr) 1979-09-21
FR2418235B1 FR2418235B1 (fr) 1982-12-10

Family

ID=12033758

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7904600A Granted FR2418235A1 (fr) 1978-02-23 1979-02-22 Procede de preparation d'acides 7-imidazolidinyl substitue 3-chloro-3-cephem-4-carboxyliques et nouveaux produits ainsi obtenus, employes notamment comme agents antibacteriens

Country Status (19)

Country Link
US (2) US4339575A (fr)
JP (1) JPS54112892A (fr)
AR (1) AR223832A1 (fr)
AU (1) AU519179B2 (fr)
BE (1) BE874377A (fr)
CA (1) CA1137976A (fr)
CH (1) CH644611A5 (fr)
DE (1) DE2907153A1 (fr)
DK (1) DK157686C (fr)
ES (1) ES477962A1 (fr)
FI (1) FI70901C (fr)
FR (1) FR2418235A1 (fr)
GB (1) GB2016469B (fr)
IE (1) IE47929B1 (fr)
IL (1) IL56726A0 (fr)
IT (1) IT1165634B (fr)
NL (1) NL7901453A (fr)
SE (1) SE445220B (fr)
SU (1) SU869560A3 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54112892A (en) * 1978-02-23 1979-09-04 Shionogi & Co Ltd Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
US4727070A (en) * 1985-11-25 1988-02-23 Bristol-Myers Company 3-Propenzl cephalosporin isomer separation process and derivative
US5229509A (en) * 1989-01-10 1993-07-20 Antibioticos, S.A. Process for the preparation of 3-chloro-cefem compounds

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL125838C (fr) * 1965-11-24
FR2168924A2 (en) * 1972-01-26 1973-09-07 Bristol Myers Co Hetacephalexin compsns - for human and veterinary antibacterial therapy, and as foodstuff additive
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
DE2442539A1 (de) * 1974-09-05 1976-04-01 Squibb & Sons Inc Cephalosporine und verfahren zu ihrer herstellung
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
AU511344B2 (en) * 1975-10-06 1980-08-14 Bristol-Myers Company "7-(2-substituted-4-(4-hydroxy phenyl) -5 ketoterahydroimidazo-1-yl) - 3- substituted thiomethyl-3-cephem-4-carboxylic acid derivatives
US4091213A (en) * 1975-12-12 1978-05-23 Bristol-Myers Company 7-Cyclizedamino-3-heterothiomethyl cephalosporin derivatives
JPS5289692A (en) * 1976-01-21 1977-07-27 Sankyo Co Ltd Penicillin and cephalosporin derivatives and preparation thereof
US4042585A (en) * 1976-03-22 1977-08-16 Eli Lilly And Company Process for preparation of 3-halomethylcephems
US4125716A (en) * 1977-12-16 1978-11-14 Bristol-Myers Company Methoxymethyl esters of substituted imidazolidinyl-3-methyl-3-cephem-4-carboxylic acids
JPS54112892A (en) * 1978-02-23 1979-09-04 Shionogi & Co Ltd Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
US4217275A (en) * 1979-02-28 1980-08-12 Bristol-Myers Company β-Lactam antibiotic esterification process using methoxymethyl methane sulfonate
US4252950A (en) * 1979-10-12 1981-02-24 Eli Lilly And Company 3-Halo cephalosporins

Also Published As

Publication number Publication date
DK157686C (da) 1990-07-16
GB2016469B (en) 1982-08-04
BE874377A (fr) 1979-06-18
IT7967402A0 (it) 1979-02-22
IT1165634B (it) 1987-04-22
FR2418235B1 (fr) 1982-12-10
IL56726A0 (en) 1979-05-31
AR223832A1 (es) 1981-09-30
FI70901B (fi) 1986-07-18
US4339575A (en) 1982-07-13
FI70901C (fi) 1986-10-27
NL7901453A (nl) 1979-08-27
AU519179B2 (en) 1981-11-12
JPS611027B2 (fr) 1986-01-13
DE2907153A1 (de) 1979-08-30
FI790582A (fi) 1979-08-24
SE445220B (sv) 1986-06-09
AU4433979A (en) 1979-08-30
SU869560A3 (ru) 1981-09-30
CH644611A5 (de) 1984-08-15
US4473567A (en) 1984-09-25
CA1137976A (fr) 1982-12-21
IE47929B1 (en) 1984-07-25
DK157686B (da) 1990-02-05
GB2016469A (en) 1979-09-26
JPS54112892A (en) 1979-09-04
ES477962A1 (es) 1979-10-16
IE790551L (en) 1979-08-23
SE7901601L (sv) 1979-08-24
DK78779A (da) 1979-08-24

Similar Documents

Publication Publication Date Title
FR2391210A1 (fr) Derives d'acides quinoleinecarboxyliques et leur utilisation comme agents antibacteriens
FR2499990B1 (fr) Procede de preparation de derives d'acides quinoleinecarboxyliques, nouveaux produits ainsi obtenus et leur utilisation comme agents antibacteriens
FR2378521A1 (fr) Derives du carbostyrile, utiles notamment comme stimulants des centres b- adrenorecepteurs, et leur procede de preparation
FR2431498A1 (fr) Procede de preparation de maytansinoides et produits obtenus par ce procede
FR2378023A1 (fr) Procede de preparation d'oximes, nouveaux produits ainsi obtenus et leur application dans la synthese de composes d'acide cephemcarboxylique 3,7-disubstitue
FR2434154A1 (fr) Nouveaux derives d'imidazole, utiles notamment comme anticonvulsivants, et leur procede de preparation
FR2369295A1 (fr) Derives
FR2376861A1 (fr) Procede de preparation d'oxazolines et nouveaux produits ainsi obtenus, utiles pour la synthese d'oxadethiacephalosporines
FR2428052A1 (fr) Nouveaux derives de 5-fluoro-(b-uridine ou 2'-desoxy-b-uridine), procede pour les preparer et agents carcinostatiques les renfermant
FR2380285A1 (fr) Nouveaux derives insatures d'acides 7-acylamido-3-cephem-4-carboxyliques, utiles notamment comme agents antibacteriens, et leur procede de preparation
FR2416227A1 (fr) Nouveaux derives de 2h-benzofuranne-3-one, utiles notamment comme anti-allergiques, et leur procede de preparation
FR2378758A1 (fr) Derives de meta-sulfanomidobenzamide et nouveaux produits ainsi obtenus, a activite notamment antiemetique et psychotrope
FR2405928A1 (fr) Procede de production de derives de n'-phenyl-n-methyluree, nouveaux produits ainsi obtenus et leur application comme herbicides
FR2381777A1 (fr) Procede de preparation d'oxazolinoazetidinones a partir d'acide 6-aminopenicillanique et nouveaux produits ainsi obtenus
FR2444029A1 (fr) Nouveaux derives d'acide phenylcyclopropane-carboxylique, leur procede de preparation et leur application comme insecticides et acaricides
FR2388802A1 (fr) Procede de production de derives d'uree et nouveaux produits ainsi obtenus
FR2363608A1 (fr) Procede de preparation de colorants " bisazoiques "
FR2436144A1 (fr) Nouveaux derives d'aurones, leur procede de preparation et leur utilisation comme produits pharmaceutiques
FR2361879A2 (fr) Nouvelles 4,5,6,7- tetrahydro-7-oxo (ou hydroxy)benzo (b)thienyl-4-amines utiles notamment comme agents de croissance pour animaux et leur procede de preparation
FR2381776A1 (fr) Procede de preparation de derives d'acide oxazolinoazetidinylbutyrique et nouveaux produits ainsi obtenus
FR2401148A1 (fr) Procede de preparation de 1-amino-3-aryloxy-2-propanols
FR2375238A1 (fr) Procede de preparation de 7-amino substitue acetamidooxadethia-cephalosporines et nouveaux produits ainsi obtenus, a activite antibacterienne
FR2384775A1 (fr) Derives de la morphine, leur procede de preparation et leur application comme medicament
FR2374302A1 (fr) Nouvelles halogenethyl-sulfones, leur procede de preparation et leur application comme substances de croissance des plantes
FR2418235A1 (fr) Procede de preparation d'acides 7-imidazolidinyl substitue 3-chloro-3-cephem-4-carboxyliques et nouveaux produits ainsi obtenus, employes notamment comme agents antibacteriens

Legal Events

Date Code Title Description
ST Notification of lapse