JPS54112892A - Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid - Google Patents

Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid

Info

Publication number
JPS54112892A
JPS54112892A JP2067578A JP2067578A JPS54112892A JP S54112892 A JPS54112892 A JP S54112892A JP 2067578 A JP2067578 A JP 2067578A JP 2067578 A JP2067578 A JP 2067578A JP S54112892 A JPS54112892 A JP S54112892A
Authority
JP
Japan
Prior art keywords
compound
cephem
chloro
carboxylic acid
cephachlor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2067578A
Other languages
English (en)
Other versions
JPS611027B2 (ja
Inventor
Yoshinobu Yukioka
Mariko Munekage
Hitoshi Minato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP2067578A priority Critical patent/JPS54112892A/ja
Priority to CA000321497A priority patent/CA1137976A/en
Priority to AU44339/79A priority patent/AU519179B2/en
Priority to FI790582A priority patent/FI70901C/fi
Priority to BE193641A priority patent/BE874377A/xx
Priority to IT67402/79A priority patent/IT1165634B/it
Priority to SE7901601A priority patent/SE445220B/sv
Priority to GB7906368A priority patent/GB2016469B/en
Priority to ES477962A priority patent/ES477962A1/es
Priority to DK078779A priority patent/DK157686C/da
Priority to IL56726A priority patent/IL56726A0/xx
Priority to FR7904600A priority patent/FR2418235A1/fr
Priority to SU792734000A priority patent/SU869560A3/ru
Priority to DE19792907153 priority patent/DE2907153A1/de
Priority to NL7901453A priority patent/NL7901453A/xx
Priority to AR275610A priority patent/AR223832A1/es
Priority to CH183279A priority patent/CH644611A5/de
Priority to IE551/79A priority patent/IE47929B1/en
Publication of JPS54112892A publication Critical patent/JPS54112892A/ja
Priority to US06/149,836 priority patent/US4339575A/en
Priority to US06/367,974 priority patent/US4473567A/en
Publication of JPS611027B2 publication Critical patent/JPS611027B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/58—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with a nitrogen atom, which is a member of a hetero ring, attached in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2067578A 1978-02-23 1978-02-23 Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid Granted JPS54112892A (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
JP2067578A JPS54112892A (en) 1978-02-23 1978-02-23 Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
CA000321497A CA1137976A (en) 1978-02-23 1979-02-14 Substituted-imidazolidinyl-3-chloro-3- cephem-4-carboxylic acids
AU44339/79A AU519179B2 (en) 1978-02-23 1979-02-16 Substituted-imidazolidinyl-3-chloro-3-cephem-4-carboxylic acids
FI790582A FI70901C (fi) 1978-02-23 1979-02-21 Foerfarande foer framstaellning av 7beta-(5-oxo-4-fenylimidazolidin-1-yl)-3-klor-3-cefem-4-karboxylsyror
FR7904600A FR2418235A1 (fr) 1978-02-23 1979-02-22 Procede de preparation d'acides 7-imidazolidinyl substitue 3-chloro-3-cephem-4-carboxyliques et nouveaux produits ainsi obtenus, employes notamment comme agents antibacteriens
IT67402/79A IT1165634B (it) 1978-02-23 1979-02-22 Derivati dell'acido imidazolininil 3 cloro 3 cefem 4 carbossilico e procedimento per la loro preparazione
SE7901601A SE445220B (sv) 1978-02-23 1979-02-22 Substituerad imidazolidinyl-3-klor-3-cefem-4-karboxylsyra
GB7906368A GB2016469B (en) 1978-02-23 1979-02-22 Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acids
ES477962A ES477962A1 (es) 1978-02-23 1979-02-22 Un procedimiento para preparar derivados de acido 3-cloro-3-cefem-4-carboxilico sustituido en 7b con imidazolidinilo.
DK078779A DK157686C (da) 1978-02-23 1979-02-22 Analogifremgangsmaade til fremstilling af 7-beta-substituerede imidazolidinyl-3-chlor-3-cephem-4-carboxylsyrer eller farmaceutisk acceptable salte deraf
IL56726A IL56726A0 (en) 1978-02-23 1979-02-22 Substituted imidazolidinyl-3-cephem-4-carboxylic acids,processes for preparing the same and pharmaceutical or veterinary formulations containing the same
BE193641A BE874377A (fr) 1978-02-23 1979-02-22 Acides 7b-(imidazolidinyl substitue)-3-chloro-3-cepheme-4-carboxyliques
DE19792907153 DE2907153A1 (de) 1978-02-23 1979-02-23 7 beta -(5-oxo-4-phenylimidazolidin- 1-yl)-3-chlor-3-cephem-4-carbonsaeurederivate und verfahren zu ihrer herstellung
SU792734000A SU869560A3 (ru) 1978-02-23 1979-02-23 Способ получени замещенных 7-(5-оксо-4-фенилимидазолидин-1-ил)-3-хлор-3-цефем-4-карбоновых кислот
NL7901453A NL7901453A (nl) 1978-02-23 1979-02-23 Gesubstitueerd imidazolidinyl-3-chloor-3-cephem-4-car- bonzuur.
AR275610A AR223832A1 (es) 1978-02-23 1979-02-23 Procedimiento para preparar acidos 7-beta(5-oxo-4-fenil-imidazolidin-1-il)-3-cloro-3-cefem-4-carboxilicos y sus sales
CH183279A CH644611A5 (de) 1978-02-23 1979-02-23 Substituierte imidazolidinyl-3-chlor-3-cephem-4-carbonsaeuren, verfahren zu ihrer herstellung und pharmazeutische zubereitungen derselben.
IE551/79A IE47929B1 (en) 1978-02-23 1979-08-08 Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acids
US06/149,836 US4339575A (en) 1978-02-23 1980-05-14 Substituted-imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
US06/367,974 US4473567A (en) 1978-02-23 1982-04-13 Substituted-imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2067578A JPS54112892A (en) 1978-02-23 1978-02-23 Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid

Publications (2)

Publication Number Publication Date
JPS54112892A true JPS54112892A (en) 1979-09-04
JPS611027B2 JPS611027B2 (ja) 1986-01-13

Family

ID=12033758

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2067578A Granted JPS54112892A (en) 1978-02-23 1978-02-23 Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid

Country Status (19)

Country Link
US (2) US4339575A (ja)
JP (1) JPS54112892A (ja)
AR (1) AR223832A1 (ja)
AU (1) AU519179B2 (ja)
BE (1) BE874377A (ja)
CA (1) CA1137976A (ja)
CH (1) CH644611A5 (ja)
DE (1) DE2907153A1 (ja)
DK (1) DK157686C (ja)
ES (1) ES477962A1 (ja)
FI (1) FI70901C (ja)
FR (1) FR2418235A1 (ja)
GB (1) GB2016469B (ja)
IE (1) IE47929B1 (ja)
IL (1) IL56726A0 (ja)
IT (1) IT1165634B (ja)
NL (1) NL7901453A (ja)
SE (1) SE445220B (ja)
SU (1) SU869560A3 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54112892A (en) * 1978-02-23 1979-09-04 Shionogi & Co Ltd Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
US4727070A (en) * 1985-11-25 1988-02-23 Bristol-Myers Company 3-Propenzl cephalosporin isomer separation process and derivative
US5229509A (en) * 1989-01-10 1993-07-20 Antibioticos, S.A. Process for the preparation of 3-chloro-cefem compounds

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL125838C (ja) * 1965-11-24
FR2168924A2 (en) * 1972-01-26 1973-09-07 Bristol Myers Co Hetacephalexin compsns - for human and veterinary antibacterial therapy, and as foodstuff additive
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
DE2442539A1 (de) * 1974-09-05 1976-04-01 Squibb & Sons Inc Cephalosporine und verfahren zu ihrer herstellung
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
AU511344B2 (en) * 1975-10-06 1980-08-14 Bristol-Myers Company "7-(2-substituted-4-(4-hydroxy phenyl) -5 ketoterahydroimidazo-1-yl) - 3- substituted thiomethyl-3-cephem-4-carboxylic acid derivatives
US4091213A (en) * 1975-12-12 1978-05-23 Bristol-Myers Company 7-Cyclizedamino-3-heterothiomethyl cephalosporin derivatives
JPS5289692A (en) * 1976-01-21 1977-07-27 Sankyo Co Ltd Penicillin and cephalosporin derivatives and preparation thereof
US4042585A (en) * 1976-03-22 1977-08-16 Eli Lilly And Company Process for preparation of 3-halomethylcephems
US4125716A (en) * 1977-12-16 1978-11-14 Bristol-Myers Company Methoxymethyl esters of substituted imidazolidinyl-3-methyl-3-cephem-4-carboxylic acids
JPS54112892A (en) * 1978-02-23 1979-09-04 Shionogi & Co Ltd Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
US4217275A (en) * 1979-02-28 1980-08-12 Bristol-Myers Company β-Lactam antibiotic esterification process using methoxymethyl methane sulfonate
US4252950A (en) * 1979-10-12 1981-02-24 Eli Lilly And Company 3-Halo cephalosporins

Also Published As

Publication number Publication date
US4339575A (en) 1982-07-13
DK78779A (da) 1979-08-24
FR2418235B1 (ja) 1982-12-10
AU4433979A (en) 1979-08-30
IL56726A0 (en) 1979-05-31
IE790551L (en) 1979-08-23
SU869560A3 (ru) 1981-09-30
DK157686C (da) 1990-07-16
IT7967402A0 (it) 1979-02-22
US4473567A (en) 1984-09-25
CH644611A5 (de) 1984-08-15
BE874377A (fr) 1979-06-18
FI790582A (fi) 1979-08-24
FI70901C (fi) 1986-10-27
NL7901453A (nl) 1979-08-27
DE2907153A1 (de) 1979-08-30
FI70901B (fi) 1986-07-18
FR2418235A1 (fr) 1979-09-21
SE7901601L (sv) 1979-08-24
AR223832A1 (es) 1981-09-30
GB2016469B (en) 1982-08-04
JPS611027B2 (ja) 1986-01-13
AU519179B2 (en) 1981-11-12
IT1165634B (it) 1987-04-22
IE47929B1 (en) 1984-07-25
SE445220B (sv) 1986-06-09
ES477962A1 (es) 1979-10-16
CA1137976A (en) 1982-12-21
DK157686B (da) 1990-02-05
GB2016469A (en) 1979-09-26

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