FR2436144A1 - Nouveaux derives d'aurones, leur procede de preparation et leur utilisation comme produits pharmaceutiques - Google Patents

Nouveaux derives d'aurones, leur procede de preparation et leur utilisation comme produits pharmaceutiques

Info

Publication number
FR2436144A1
FR2436144A1 FR7922802A FR7922802A FR2436144A1 FR 2436144 A1 FR2436144 A1 FR 2436144A1 FR 7922802 A FR7922802 A FR 7922802A FR 7922802 A FR7922802 A FR 7922802A FR 2436144 A1 FR2436144 A1 FR 2436144A1
Authority
FR
France
Prior art keywords
pharmaceuticals
novel
preparation process
derivatives
auron
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7922802A
Other languages
English (en)
Other versions
FR2436144B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of FR2436144A1 publication Critical patent/FR2436144A1/fr
Application granted granted Critical
Publication of FR2436144B1 publication Critical patent/FR2436144B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne de nouveaux dérivés d'aurones, leur procédé de préparation et leur utilisation comme produits pharmaceutiques. Les aurones substituées de l'invention répondent à la formule :
FR7922802A 1978-09-13 1979-09-12 Nouveaux derives d'aurones, leur procede de preparation et leur utilisation comme produits pharmaceutiques Expired FR2436144B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7836705 1978-09-13
GB7931652A GB2030142B (en) 1978-09-13 1979-09-12 Aurone derivatives

Publications (2)

Publication Number Publication Date
FR2436144A1 true FR2436144A1 (fr) 1980-04-11
FR2436144B1 FR2436144B1 (fr) 1986-02-28

Family

ID=26268838

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7922802A Expired FR2436144B1 (fr) 1978-09-13 1979-09-12 Nouveaux derives d'aurones, leur procede de preparation et leur utilisation comme produits pharmaceutiques

Country Status (7)

Country Link
US (1) US4259340A (fr)
BE (1) BE878759A (fr)
DE (1) DE2936730A1 (fr)
FR (1) FR2436144B1 (fr)
GB (1) GB2030142B (fr)
LU (1) LU81676A1 (fr)
NL (1) NL7906823A (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1093805B (it) * 1978-01-31 1985-07-26 Erba Carlo Spa Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione
GR81257B (fr) * 1982-12-04 1984-12-11 Lilly Industries Ltd
US4532257A (en) * 1982-12-04 1985-07-30 Lilly Industries Limited Certain aurones and their use in the treatment of allergies
GB2131688A (en) * 1982-12-04 1984-06-27 Lilly Industries Ltd Pharmaceutical use of aurone- type compounds
US5026759A (en) * 1985-05-08 1991-06-25 Du Pont Merck Pharmaceutical 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
SU1600627A3 (ru) * 1985-05-08 1990-10-15 Е.И.Дюпон Де Немур Энд Компани (Фирма) Способ получени 2-замещенных 1-нафтолов
JP2001076775A (ja) * 1999-09-07 2001-03-23 Fuji Photo Film Co Ltd 光電変換素子および光電池
EP1250331B1 (fr) * 2000-01-28 2004-11-03 MERCK PATENT GmbH Formulation de protection contre les agressions oxydantes, contenant des derives de benzofuranone
DE10030646A1 (de) * 2000-06-29 2002-01-10 Henkel Kgaa Indigo-Derivate
EA023852B1 (ru) * 2014-02-12 2016-07-29 Институт Нефтехимических Процессов Им. Академика Ю. Мамедалиева, Нан Азербайджана 2-гидрокси-5-(1-метилциклоалкил)ацетофеноны - стабилизаторы полистирола
WO2017180644A1 (fr) 2016-04-11 2017-10-19 Middle Tennessee State University Aurones thérapeutiques

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975380A (en) * 1974-06-03 1976-08-17 Smithkline Corporation Substituted aurones
FR2396756A1 (fr) * 1977-07-06 1979-02-02 Inst Nat Sante Rech Med Nouvelles benzylidene-2-benzofurannones-3, leur obtention et leur application a titre de medicaments
FR2416227A1 (fr) * 1978-01-31 1979-08-31 Erba Farmitalia Nouveaux derives de 2h-benzofuranne-3-one, utiles notamment comme anti-allergiques, et leur procede de preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143055A (en) * 1978-03-27 1979-03-06 Gruppo Lepetit S.P.A. 2,4,6-trisubstituted-2,3-dihydro-benzofuran derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975380A (en) * 1974-06-03 1976-08-17 Smithkline Corporation Substituted aurones
FR2396756A1 (fr) * 1977-07-06 1979-02-02 Inst Nat Sante Rech Med Nouvelles benzylidene-2-benzofurannones-3, leur obtention et leur application a titre de medicaments
FR2416227A1 (fr) * 1978-01-31 1979-08-31 Erba Farmitalia Nouveaux derives de 2h-benzofuranne-3-one, utiles notamment comme anti-allergiques, et leur procede de preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/55 *

Also Published As

Publication number Publication date
US4259340A (en) 1981-03-31
DE2936730A1 (de) 1980-03-27
LU81676A1 (fr) 1981-04-17
GB2030142A (en) 1980-04-02
GB2030142B (en) 1983-07-20
NL7906823A (nl) 1980-03-17
FR2436144B1 (fr) 1986-02-28
BE878759A (fr) 1980-03-12

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Legal Events

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