BE878759A - Nouveaux derives d'aurones, leur procede de preparation et leur utilisation comme produits pharmaceutiques - Google Patents

Nouveaux derives d'aurones, leur procede de preparation et leur utilisation comme produits pharmaceutiques

Info

Publication number
BE878759A
BE878759A BE6/46938A BE6046938A BE878759A BE 878759 A BE878759 A BE 878759A BE 6/46938 A BE6/46938 A BE 6/46938A BE 6046938 A BE6046938 A BE 6046938A BE 878759 A BE878759 A BE 878759A
Authority
BE
Belgium
Prior art keywords
auron
pharmaceuticals
derivatives
novel
preparation process
Prior art date
Application number
BE6/46938A
Other languages
English (en)
Inventor
S R Baker
W J Ross
W B Jamieson
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of BE878759A publication Critical patent/BE878759A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE6/46938A 1978-09-13 1979-09-12 Nouveaux derives d'aurones, leur procede de preparation et leur utilisation comme produits pharmaceutiques BE878759A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7836705 1978-09-13
GB7931652A GB2030142B (en) 1978-09-13 1979-09-12 Aurone derivatives

Publications (1)

Publication Number Publication Date
BE878759A true BE878759A (fr) 1980-03-12

Family

ID=26268838

Family Applications (1)

Application Number Title Priority Date Filing Date
BE6/46938A BE878759A (fr) 1978-09-13 1979-09-12 Nouveaux derives d'aurones, leur procede de preparation et leur utilisation comme produits pharmaceutiques

Country Status (7)

Country Link
US (1) US4259340A (fr)
BE (1) BE878759A (fr)
DE (1) DE2936730A1 (fr)
FR (1) FR2436144B1 (fr)
GB (1) GB2030142B (fr)
LU (1) LU81676A1 (fr)
NL (1) NL7906823A (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1093805B (it) * 1978-01-31 1985-07-26 Erba Carlo Spa Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione
GB2131688A (en) * 1982-12-04 1984-06-27 Lilly Industries Ltd Pharmaceutical use of aurone- type compounds
US4532257A (en) * 1982-12-04 1985-07-30 Lilly Industries Limited Certain aurones and their use in the treatment of allergies
HUT36107A (en) * 1982-12-04 1985-08-28 Lilly Industries Ltd Process for production of new aurone-derivatives and medical preparatives consisting of such compounds
ZA863425B (en) * 1985-05-08 1988-01-27 Du Pont 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
US5026759A (en) * 1985-05-08 1991-06-25 Du Pont Merck Pharmaceutical 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
JP2001076775A (ja) * 1999-09-07 2001-03-23 Fuji Photo Film Co Ltd 光電変換素子および光電池
US6903134B2 (en) * 2000-01-28 2005-06-07 Merck Patent Gmbh Formulation comprising benzofuranone derivatives for protection against oxidative stress
DE10030646A1 (de) * 2000-06-29 2002-01-10 Henkel Kgaa Indigo-Derivate
EA023852B1 (ru) * 2014-02-12 2016-07-29 Институт Нефтехимических Процессов Им. Академика Ю. Мамедалиева, Нан Азербайджана 2-гидрокси-5-(1-метилциклоалкил)ацетофеноны - стабилизаторы полистирола
WO2017180644A1 (fr) 2016-04-11 2017-10-19 Middle Tennessee State University Aurones thérapeutiques

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975380A (en) * 1974-06-03 1976-08-17 Smithkline Corporation Substituted aurones
FR2396756A1 (fr) 1977-07-06 1979-02-02 Inst Nat Sante Rech Med Nouvelles benzylidene-2-benzofurannones-3, leur obtention et leur application a titre de medicaments
IT1093805B (it) 1978-01-31 1985-07-26 Erba Carlo Spa Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione
US4143055A (en) * 1978-03-27 1979-03-06 Gruppo Lepetit S.P.A. 2,4,6-trisubstituted-2,3-dihydro-benzofuran derivatives

Also Published As

Publication number Publication date
US4259340A (en) 1981-03-31
DE2936730A1 (de) 1980-03-27
LU81676A1 (fr) 1981-04-17
FR2436144A1 (fr) 1980-04-11
GB2030142A (en) 1980-04-02
FR2436144B1 (fr) 1986-02-28
GB2030142B (en) 1983-07-20
NL7906823A (nl) 1980-03-17

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: LILLY INDUSTRIES LTD

Effective date: 19860930