FR2408610A1 - Derives de 2,6-diphenyl-3,7-dioxabicyclo-(3,3,0)-octane-4,8-dione, leur procede de preparation et leur application en therapeutique - Google Patents

Derives de 2,6-diphenyl-3,7-dioxabicyclo-(3,3,0)-octane-4,8-dione, leur procede de preparation et leur application en therapeutique

Info

Publication number
FR2408610A1
FR2408610A1 FR7832242A FR7832242A FR2408610A1 FR 2408610 A1 FR2408610 A1 FR 2408610A1 FR 7832242 A FR7832242 A FR 7832242A FR 7832242 A FR7832242 A FR 7832242A FR 2408610 A1 FR2408610 A1 FR 2408610A1
Authority
FR
France
Prior art keywords
group
dioxabicyclo
octane
diphenyl
preparation process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7832242A
Other languages
English (en)
Inventor
Hamao Umezawa
Tomio Takeuchi
Masaaki Ishizuka
Yoshiki Kumada
Katsuji Yamashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of FR2408610A1 publication Critical patent/FR2408610A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A.DERIVES DE 2,6-DIPHENYL-3,7-DIOXABICYCLO-3,30-OCTANE-4,8-DIONE, LEUR PROCEDE DE PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE. B.CES DERIVES CORRESPONDENT A LA FORMULE: (CF DESSIN DANS BOPI) DANS LAQUELLE R, R, R ET R REPRESENTE CHACUN DES GROUPEMENTS SEMBLABLES OU DIFFERENTS QUI SONT CHOISIS DANS LE GROUPE COMPRENANT UN GROUPEMENT HYDROXYLE, UN GROUPEMENT ALCOXYLE C C, UN ATOME D'HALOGENE, UN GROUPEMENT THIOALCOXYMETHYLE C C, UN GROUPEMENT ALKYLE C C, UN GROUPEMENT ALCOXYMETHYLE C C, ET UN ATOME D'HYDROGENE, POURVU QUE LES CAS SUIVANTS EN SOIENT EXCLUS; LE CAS OU R ET R ETANT DES GROUPEMENTS HYDROXYLE, R ET R SONT DES ATOMES D'HYDROGENE, LE CAS OU R ETANT UN GROUPEMENT METHOXYLE, R EST UN GROUPEMENT HYDROXYLE, ET R ET R SONT DES ATOMES D'HYDROGENE, LE CAS OU R ETANT UN GROUPEMENT METHOXYLE, R EST UN GROUPEMENT HYDROXYLE, R EST UN GROUPEMENT METHOXYLE ET R EST UN ATOME D'HYDROGENE, ET LE CAS OU R ET R ETANT DES GROUPEMENTS METHOXYLE, R ET R SONT DES ATOMES D'HYDROGENE. C.MEDICAMENTS.
FR7832242A 1977-11-15 1978-11-15 Derives de 2,6-diphenyl-3,7-dioxabicyclo-(3,3,0)-octane-4,8-dione, leur procede de preparation et leur application en therapeutique Withdrawn FR2408610A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13742077A JPS5473789A (en) 1977-11-15 1977-11-15 2,6-diphenyl-3,7-dioxabicyclo-3.3.0-octane 4,8-dione derivative and anticarcinogens, catechol-o-methyl transferase inhibitors and adenosine 3',5'-cyclic phosphoric acid phosphodiesterase inhibitors containing the derivative as active component

Publications (1)

Publication Number Publication Date
FR2408610A1 true FR2408610A1 (fr) 1979-06-08

Family

ID=15198205

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7832242A Withdrawn FR2408610A1 (fr) 1977-11-15 1978-11-15 Derives de 2,6-diphenyl-3,7-dioxabicyclo-(3,3,0)-octane-4,8-dione, leur procede de preparation et leur application en therapeutique

Country Status (10)

Country Link
JP (1) JPS5473789A (fr)
AR (1) AR217335A1 (fr)
BE (1) BE871994A (fr)
DE (1) DE2849107A1 (fr)
ES (1) ES475050A1 (fr)
FR (1) FR2408610A1 (fr)
GB (1) GB2010273A (fr)
IT (1) IT1109272B (fr)
NL (1) NL7811308A (fr)
SE (1) SE7811759L (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62581A (ja) * 1985-06-26 1987-01-06 Takemoto Oil & Fat Co Ltd フエノ−ル性天然抗酸化性物質の製造方法
JPS6330416A (ja) * 1986-07-24 1988-02-09 Wakunaga Pharmaceut Co Ltd 脳循環代謝改善剤
US6588625B2 (en) 2001-04-24 2003-07-08 Abbott Laboratories Sample handling system
KR100479405B1 (ko) * 2002-05-24 2005-03-30 주식회사 싸이제닉 신남산 이합체, 그 제조방법 및 퇴행성 뇌질환 치료를위한 그의 용도
JP2011195465A (ja) * 2010-03-17 2011-10-06 Wakayama Prefecture 桂皮酸誘導体の製造方法及び桂皮酸誘導体
JP5914897B2 (ja) * 2012-03-08 2016-05-11 和歌山県 フロフラン誘導体の製造方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52102433A (en) * 1976-02-19 1977-08-27 Microbial Chem Res Found Hypotensive agents containing 1,4-dihydroxy-1,4-di-(3,5-dimethoxy-4-hy droxyphenyl)butane-2,3-dicarboxylic acid dilactone as main component
JPS52136193A (en) * 1976-05-10 1977-11-14 Microbial Chem Res Found Novel dehydrodicaffeic acid dilactone

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52102433A (en) * 1976-02-19 1977-08-27 Microbial Chem Res Found Hypotensive agents containing 1,4-dihydroxy-1,4-di-(3,5-dimethoxy-4-hy droxyphenyl)butane-2,3-dicarboxylic acid dilactone as main component
JPS52136193A (en) * 1976-05-10 1977-11-14 Microbial Chem Res Found Novel dehydrodicaffeic acid dilactone

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CA1935 *
CA1978 *
EXBK/76 *

Also Published As

Publication number Publication date
SE7811759L (sv) 1979-05-16
ES475050A1 (es) 1979-04-16
DE2849107A1 (de) 1979-05-17
JPS5473789A (en) 1979-06-13
IT7851906A0 (it) 1978-11-15
GB2010273A (en) 1979-06-27
NL7811308A (nl) 1979-05-17
IT1109272B (it) 1985-12-16
AR217335A1 (es) 1980-03-14
BE871994A (fr) 1979-05-14

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Legal Events

Date Code Title Description
ST Notification of lapse