FR2397402A1 - Nouveaux analogues de prostaglandines et les compositions pharmaceutiques les contenant - Google Patents

Nouveaux analogues de prostaglandines et les compositions pharmaceutiques les contenant

Info

Publication number
FR2397402A1
FR2397402A1 FR7820818A FR7820818A FR2397402A1 FR 2397402 A1 FR2397402 A1 FR 2397402A1 FR 7820818 A FR7820818 A FR 7820818A FR 7820818 A FR7820818 A FR 7820818A FR 2397402 A1 FR2397402 A1 FR 2397402A1
Authority
FR
France
Prior art keywords
pharmaceutical compositions
compositions containing
prostaglandin analogues
new prostaglandin
alkylene group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7820818A
Other languages
English (en)
Other versions
FR2397402B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of FR2397402A1 publication Critical patent/FR2397402A1/fr
Application granted granted Critical
Publication of FR2397402B1 publication Critical patent/FR2397402B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018—Esters of cycloaliphatic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne de nouveaux analogues de prostaglandines. Ces composés ont la formule ci-dessous, dans laquelle A est un noyau alicyclique de PGF, PGE ou PGA, B = groupe alcoylène ou groupement alcoylène-phénylène-alcoylène, X = éthylène ou vinyléne cis, Y = éthylène ou vinylène trans, W = éthylène ou vinylène trans, Z = halogène, et R**1 = H ou alcoyle. Applications pharmacologiques dans les domaines habituels pour les prostaglandines.
FR7820818A 1977-07-14 1978-07-12 Nouveaux analogues de prostaglandines et les compositions pharmaceutiques les contenant Granted FR2397402A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52083558A JPS6022708B2 (ja) 1977-07-14 1977-07-14 プロスタグランジン類似化合物

Publications (2)

Publication Number Publication Date
FR2397402A1 true FR2397402A1 (fr) 1979-02-09
FR2397402B1 FR2397402B1 (fr) 1983-06-24

Family

ID=13805833

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7820818A Granted FR2397402A1 (fr) 1977-07-14 1978-07-12 Nouveaux analogues de prostaglandines et les compositions pharmaceutiques les contenant

Country Status (6)

Country Link
US (1) US4208428A (fr)
JP (1) JPS6022708B2 (fr)
DE (1) DE2830478C2 (fr)
FR (1) FR2397402A1 (fr)
GB (1) GB2002355B (fr)
IT (1) IT1097159B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2947526A1 (de) * 1978-11-29 1980-06-12 Ono Pharmaceutical Co Prostacyclin-analoge
JPH0633309U (ja) * 1992-09-30 1994-04-28 スタンレー電気株式会社 車両用灯具のモール取付構造
CN1329359C (zh) * 1999-04-01 2007-08-01 埃斯佩里安医疗公司 醚化合物,及其组合物和用途
DE60010913T2 (de) 1999-10-15 2005-06-09 Sucampo Ag Bizyklische Verbindungen, Zusammenstellung und Verfahren zu ihrer Stabilisierung
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2263756A1 (fr) * 1974-03-14 1975-10-10 Ono Pharmaceutical Co

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117119A (en) * 1975-03-11 1978-09-26 Ono Pharmaceutical Company 15-cyclobutyl-prostaglandins
US3997588A (en) * 1975-05-15 1976-12-14 G. D. Searle & Co. 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2263756A1 (fr) * 1974-03-14 1975-10-10 Ono Pharmaceutical Co

Also Published As

Publication number Publication date
GB2002355B (en) 1982-04-21
IT7825613A0 (it) 1978-07-12
US4208428A (en) 1980-06-17
DE2830478C2 (de) 1985-10-24
IT1097159B (it) 1985-08-26
FR2397402B1 (fr) 1983-06-24
DE2830478A1 (de) 1979-02-01
JPS5419946A (en) 1979-02-15
GB2002355A (en) 1979-02-21
JPS6022708B2 (ja) 1985-06-03

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Legal Events

Date Code Title Description
ST Notification of lapse