SE7909480L - 2,5-inter-o-fenylen-3,4-dinor-pfg och pg1 foreningar - Google Patents
2,5-inter-o-fenylen-3,4-dinor-pfg och pg1 foreningarInfo
- Publication number
- SE7909480L SE7909480L SE7909480A SE7909480A SE7909480L SE 7909480 L SE7909480 L SE 7909480L SE 7909480 A SE7909480 A SE 7909480A SE 7909480 A SE7909480 A SE 7909480A SE 7909480 L SE7909480 L SE 7909480L
- Authority
- SE
- Sweden
- Prior art keywords
- phenylene
- inter
- prostacyclin
- alpha
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- KAQKFAOMNZTLHT-OZUDYXHBSA-N prostaglandin I2 Chemical compound O1\C(=C/CCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-OZUDYXHBSA-N 0.000 abstract 3
- 229960001123 epoprostenol Drugs 0.000 abstract 2
- 230000000144 pharmacologic effect Effects 0.000 abstract 2
- PXGPLTODNUVGFL-BRIYLRKRSA-N (E,Z)-(1R,2R,3R,5S)-7-(3,5-Dihydroxy-2-((3S)-(3-hydroxy-1-octenyl))cyclopentyl)-5-heptenoic acid Chemical compound CCCCC[C@H](O)C=C[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=CCCCC(O)=O PXGPLTODNUVGFL-BRIYLRKRSA-N 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 229940127218 antiplatelet drug Drugs 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5456—Arylalkanephosphonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96284578A | 1978-11-22 | 1978-11-22 | |
| US06/062,443 US4312810A (en) | 1978-11-22 | 1979-07-31 | 2,5-Inter-o-phenylene-3,4-dinor-5,9α-epoxy-9-deoxy-PGF1 compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7909480L true SE7909480L (sv) | 1980-05-23 |
Family
ID=26742270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7909480A SE7909480L (sv) | 1978-11-22 | 1979-11-16 | 2,5-inter-o-fenylen-3,4-dinor-pfg och pg1 foreningar |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4312810A (sv) |
| AU (1) | AU529927B2 (sv) |
| CA (1) | CA1175822A (sv) |
| CH (2) | CH643839A5 (sv) |
| DE (1) | DE2945781A1 (sv) |
| FR (2) | FR2442235A1 (sv) |
| GB (3) | GB2053222B (sv) |
| IT (1) | IT7927410A0 (sv) |
| NL (1) | NL7908484A (sv) |
| SE (1) | SE7909480L (sv) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3029984C2 (de) | 1980-08-08 | 1983-12-15 | Grünenthal GmbH, 5190 Stolberg | 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel |
| IL65387A0 (en) * | 1981-04-14 | 1982-05-31 | Chinoin Gyogyszer Es Vegyeszet | 2,3,4-trinor-m-inter-phenylene-prostaglandin derivatives and a process for the preparation thereof |
| US4401824A (en) * | 1982-03-08 | 1983-08-30 | The Upjohn Company | Benzopyran compounds, derivatives of prostaglandins |
| HU192909B (en) * | 1985-01-17 | 1987-07-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing interfuranylene-prostacycline derivatives |
| US5661178A (en) * | 1995-09-01 | 1997-08-26 | Allergan | Method for effecting vasodilation with (1,5-inter)aryl prostaglandin derivatives |
| JP6569661B2 (ja) | 2014-02-27 | 2019-09-04 | 小野薬品工業株式会社 | 選択的ｅｐ２アゴニスト活性を有する化合物 |
| ES2837399T3 (es) | 2015-07-23 | 2021-06-30 | Ono Pharmaceutical Co | Derivados de ácido 2-(octahidrociclopenta(b)piran-2-il)1,3-tiazol-4-carboxílico y compuestos relacionados como agonistas de EP2 con actividad reductora de la presión intraocular |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3728382A (en) * | 1970-05-04 | 1973-04-17 | Upjohn Co | 15-methyl and 15-ethyl prostaglandin analogs |
| US3903131A (en) * | 1971-04-12 | 1975-09-02 | Upjohn Co | 16 and 16,16-dimethyl PGE{HD 2{B |
| US3962293A (en) * | 1973-07-20 | 1976-06-08 | The Upjohn Company | 13,14-Dihydro-16-fluoro prostaglandin F1 |
| US4026909A (en) * | 1975-07-14 | 1977-05-31 | The Upjohn Company | Cis-13-PGF2.sub.α analogs |
| ZA764727B (en) * | 1975-09-02 | 1977-07-27 | Upjohn Co | Prostanoic acid derivatives |
| US4029681A (en) * | 1976-02-13 | 1977-06-14 | The Upjohn Company | 13,14-Didehydro-PG analogs |
| US4123441A (en) * | 1976-09-22 | 1978-10-31 | The Upjohn Company | Enlarged-hetero-ring prostacyclin analogs |
-
1979
- 1979-07-31 US US06/062,443 patent/US4312810A/en not_active Expired - Lifetime
- 1979-10-31 AU AU52368/79A patent/AU529927B2/en not_active Ceased
- 1979-11-09 CA CA000339557A patent/CA1175822A/en not_active Expired
- 1979-11-13 DE DE19792945781 patent/DE2945781A1/de not_active Withdrawn
- 1979-11-16 SE SE7909480A patent/SE7909480L/sv not_active Application Discontinuation
- 1979-11-19 IT IT7927410A patent/IT7927410A0/it unknown
- 1979-11-21 FR FR7928709A patent/FR2442235A1/fr active Granted
- 1979-11-21 GB GB8026877A patent/GB2053222B/en not_active Expired
- 1979-11-21 GB GB8026878A patent/GB2053223B/en not_active Expired
- 1979-11-21 GB GB7940327A patent/GB2037752B/en not_active Expired
- 1979-11-21 NL NL7908484A patent/NL7908484A/xx not_active Application Discontinuation
- 1979-11-22 CH CH1043279A patent/CH643839A5/de not_active IP Right Cessation
-
1980
- 1980-03-14 FR FR8005710A patent/FR2449085A1/fr active Granted
-
1983
- 1983-09-20 CH CH511383A patent/CH643828A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US4312810A (en) | 1982-01-26 |
| NL7908484A (nl) | 1980-05-27 |
| GB2053223A (en) | 1981-02-04 |
| GB2053222B (en) | 1982-10-06 |
| IT7927410A0 (it) | 1979-11-19 |
| GB2053222A (en) | 1981-02-04 |
| CA1175822A (en) | 1984-10-09 |
| AU5236879A (en) | 1980-05-29 |
| DE2945781A1 (de) | 1980-06-12 |
| CH643828A5 (de) | 1984-06-29 |
| FR2442235A1 (fr) | 1980-06-20 |
| CH643839A5 (de) | 1984-06-29 |
| AU529927B2 (en) | 1983-06-23 |
| GB2053223B (en) | 1982-10-06 |
| FR2449085B1 (sv) | 1982-03-12 |
| GB2037752A (en) | 1980-07-16 |
| FR2449085A1 (fr) | 1980-09-12 |
| FR2442235B1 (sv) | 1982-12-03 |
| GB2037752B (en) | 1982-11-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 7909480-1 Effective date: 19800305 |