FR2394511A1 - Nouveaux analogues de prostaglandines et compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux analogues de prostaglandines et compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2394511A1
FR2394511A1 FR7817584A FR7817584A FR2394511A1 FR 2394511 A1 FR2394511 A1 FR 2394511A1 FR 7817584 A FR7817584 A FR 7817584A FR 7817584 A FR7817584 A FR 7817584A FR 2394511 A1 FR2394511 A1 FR 2394511A1
Authority
FR
France
Prior art keywords
pharmaceutical compositions
compositions containing
prostaglandin analogues
new prostaglandin
ethylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7817584A
Other languages
English (en)
Other versions
FR2394511B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of FR2394511A1 publication Critical patent/FR2394511A1/fr
Application granted granted Critical
Publication of FR2394511B1 publication Critical patent/FR2394511B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018—Esters of cycloaliphatic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne de nouveaux analogues de prostaglantines. Ces composés ont la formule ci-dessous, dans laquelle A est un noyau alicyclique de PGF, PGE ou PGA, X = vinylène trans ou éthylène, Y = vinylène cis ou éthylène, R = groupe COOR**4 (R**4 = H ou alcoyle) ou CH2 OR**5 (R**5 = H ou alcoyl-carbonyle), et R**1, R**2, R**3, identiques ou différents, sont des atomes H, des groupes alcoyles ou des groupes aryles substitués ou non. Applications pharmacologiques dans les domaines habituels pour les prostaglandines.
FR7817584A 1977-06-14 1978-06-13 Nouveaux analogues de prostaglandines et compositions pharmaceutiques qui les contiennent Granted FR2394511A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB24867/77A GB1588196A (en) 1977-06-14 1977-06-14 Prostaglandin analogues

Publications (2)

Publication Number Publication Date
FR2394511A1 true FR2394511A1 (fr) 1979-01-12
FR2394511B1 FR2394511B1 (fr) 1980-10-31

Family

ID=10218514

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7817584A Granted FR2394511A1 (fr) 1977-06-14 1978-06-13 Nouveaux analogues de prostaglandines et compositions pharmaceutiques qui les contiennent

Country Status (6)

Country Link
US (1) US4275075A (fr)
JP (1) JPS6022707B2 (fr)
DE (1) DE2825440C2 (fr)
FR (1) FR2394511A1 (fr)
GB (1) GB1588196A (fr)
IT (1) IT1096650B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2834249A1 (de) * 1978-08-04 1980-02-28 Hoechst Ag Neue prostaglandinderivate in der delta 2-11-desoxy-pgf tief 2 bzw. pge tief 2 -reihe
JPS6130554A (ja) * 1984-07-23 1986-02-12 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物のある特定の立体配置を有する異性体及びそれらを有効成分として含有する治療剤
US5221689A (en) * 1984-07-23 1993-06-22 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues, processes for their preparation and pharmaceutical compositions containing them
JP2609608B2 (ja) * 1986-09-29 1997-05-14 株式会社東芝 半導体装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2212146A1 (fr) * 1972-12-29 1974-07-26 Ono Pharmaceutical Co
FR2255056A1 (fr) * 1973-12-25 1975-07-18 Ono Pharmaceutical Co

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087620A (en) * 1975-07-17 1978-05-02 Ono Pharmaceutical Company 15-Cycloalkyl-prostaglandin derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2212146A1 (fr) * 1972-12-29 1974-07-26 Ono Pharmaceutical Co
FR2255056A1 (fr) * 1973-12-25 1975-07-18 Ono Pharmaceutical Co

Also Published As

Publication number Publication date
US4275075A (en) 1981-06-23
DE2825440A1 (de) 1979-01-04
GB1588196A (en) 1981-04-15
FR2394511B1 (fr) 1980-10-31
JPS545953A (en) 1979-01-17
JPS6022707B2 (ja) 1985-06-03
IT7824459A0 (it) 1978-06-12
IT1096650B (it) 1985-08-26
DE2825440C2 (de) 1985-10-24

Similar Documents

Publication Publication Date Title
FR2422635A1 (fr) Analogues de la prostaglandine i2 et compositions pharmaceutiques les contenant
US4108900A (en) 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-ω-phenoxy-PGA11 compounds
FR2396749A1 (fr) Analogues de prostacycline
FR2403333A1 (fr) Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant
US4161606A (en) ω-Aryl-cis-13-inter-oxa-PGA compounds
FR2418794A1 (fr) Analogues de la prostaglandine i2 et compositions pharmaceutiques les contenant
FR2381043A1 (fr) Nouveaux analogues de prostaglandines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2404005A1 (fr) Analogues de la prostaglandine i2 et compositions pharmaceutiques les contenant
US4097508A (en) Cis-4,5-didehydro-13,14 dihydro-9, dioxy PGF compounds
FR2394511A1 (fr) Nouveaux analogues de prostaglandines et compositions pharmaceutiques qui les contiennent
FR2442844A1 (fr) Analogues de la prostaglandine i1 et compositions pharmaceutiques les contenant
FR2397402A1 (fr) Nouveaux analogues de prostaglandines et les compositions pharmaceutiques les contenant
US4075247A (en) 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-3-oxa-11-deoxy-PGE.sub.1 compounds
FR2378777A1 (fr) Nouveaux analogues de prostaglandines
FR2366276A1 (fr) Aza-13 prostaglandines
FR2447375A1 (fr) Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant
FR2358380A1 (fr) Procede pour la preparation de cetones cycliques
FR2419935A1 (fr) Analogues de la prostaglandine i2 et compositions pharmaceutiques les contenant
US4065628A (en) 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGE, compounds
US4001286A (en) Phenyl-substituted prostaglandin-β-type anologs
FR2372820A1 (fr) Procede de preparation de derives d'alcenyl-6 oxa-2 bicyclo (3-3-0) octanones-3, intermediaires pour la preparation de prostaglandines
US4130591A (en) 2-Decarboxy-2-hydroxy-methyl-13,14-didehydro-16-phenoxy PGF compounds
FR2449680A1 (fr) Analogues de la prostaglandine i2 et compositions pharmaceutiques les contenant
FR2404637A1 (fr) Analogues de prostaglandines et compositions pharmaceutiques les contenant
FR2403332A1 (fr) Additifs pour lubrifiants pour pression extreme, a base de composes de tetrasulfure

Legal Events

Date Code Title Description
ST Notification of lapse