FR2382895A1 - Composition pharmaceutique a base d'un steroide anti-inflammatoire - Google Patents

Composition pharmaceutique a base d'un steroide anti-inflammatoire

Info

Publication number
FR2382895A1
FR2382895A1 FR7806337A FR7806337A FR2382895A1 FR 2382895 A1 FR2382895 A1 FR 2382895A1 FR 7806337 A FR7806337 A FR 7806337A FR 7806337 A FR7806337 A FR 7806337A FR 2382895 A1 FR2382895 A1 FR 2382895A1
Authority
FR
France
Prior art keywords
pharmaceutical composition
composition based
inflammatory steroid
steroid
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7806337A
Other languages
English (en)
Other versions
FR2382895B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2382895A1 publication Critical patent/FR2382895A1/fr
Application granted granted Critical
Publication of FR2382895B1 publication Critical patent/FR2382895B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention a trait au domaine de la pharmacie. Elle concerne des préparations topiques renfermant des stéroïdes anti-inflammatoires. Les préparations de l'invention peuvent être des pommades ou des solutions qui renferment de l'éther stéarylique de polyoxypropylène 15 comme agent de solubilisation du stéroïde.
FR7806337A 1977-03-07 1978-03-06 Composition pharmaceutique a base d'un steroide anti-inflammatoire Granted FR2382895A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/774,753 US4083974A (en) 1977-03-07 1977-03-07 Topical steroidal anti-inflammatory preparations containing polyoxypropylene 15 stearyl ether

Publications (2)

Publication Number Publication Date
FR2382895A1 true FR2382895A1 (fr) 1978-10-06
FR2382895B1 FR2382895B1 (fr) 1980-08-29

Family

ID=25102178

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7806337A Granted FR2382895A1 (fr) 1977-03-07 1978-03-06 Composition pharmaceutique a base d'un steroide anti-inflammatoire

Country Status (6)

Country Link
US (1) US4083974A (fr)
JP (1) JPS53109934A (fr)
BE (1) BE864645A (fr)
DE (1) DE2806669A1 (fr)
FR (1) FR2382895A1 (fr)
GB (1) GB1547357A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2491333A1 (fr) * 1980-10-06 1982-04-09 Glaxo Group Ltd Compositions pharmaceutiques administrables par voie topique et contenant des steroides anti-inflammatoires

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215116A (en) * 1978-06-30 1980-07-29 Block Drug Company Inc. Propoxylate toxicants
US4213979A (en) * 1978-12-18 1980-07-22 Plough, Inc. Stable sprayable hydrocortisone product
ATE6466T1 (de) * 1979-10-26 1984-03-15 Smith And Nephew Associated Companies P.L.C. Autoklavierbare emulsionen.
US4436638A (en) 1981-04-15 1984-03-13 Exxon Research & Engineering Co. Additive composition for release of stuck drill pipe
US4464269A (en) * 1981-07-29 1984-08-07 Exxon Research & Engineering Co. Additive composition for release of stuck drill pipe
SE443914B (sv) * 1984-10-01 1986-03-17 Torkel Ingemar Fischer Medel for en overkenslighetstest
US4808610A (en) * 1986-10-02 1989-02-28 Schering Corporation Mometasone furoate anti-inflammatory cream composition using hexylene glycol
US4954332A (en) * 1987-10-22 1990-09-04 The Procter & Gamble Company Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent
US4959205A (en) * 1989-03-23 1990-09-25 Collagen Corporation Composition and method for treatment of dermal inflammation
US5061700A (en) * 1989-11-16 1991-10-29 Gordon Jay Dow Glyceryl acetate ointment vehicles
US6086903A (en) * 1996-02-26 2000-07-11 The Proctor & Gamble Company Personal treatment compositions and/or cosmetic compositions containing enduring perfume
EP0975370B9 (fr) * 1997-05-21 2004-11-03 The Board Of Trustees Of The Leland Stanford Junior University Composition et procede permettant d'ameliorer les transports a travers des membranes biologiques
FR2787703B1 (fr) * 1998-12-29 2001-01-26 Oreal Nanoemulsion a base d'ethers gras ethoxyles ou d'esters gras ethoxyles, et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
HU230045B1 (hu) * 1999-04-23 2015-06-29 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Bőrgyógyászati alkalmazásra szolgáló nem vizes gyógyszerkészítmény
US6765019B1 (en) * 1999-05-06 2004-07-20 University Of Kentucky Research Foundation Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US7019194B2 (en) 2001-02-09 2006-03-28 Lennart Hansson SCCE modified transgenic mammals and their use as models of human disease
WO2002089739A2 (fr) * 2001-05-09 2002-11-14 Newbiotics, Inc. Promedicaments actives par peptide deformylase
US20040022741A1 (en) * 2001-06-15 2004-02-05 Crutchfield Charles E. Topical steroid spray
US20090304603A1 (en) * 2001-06-15 2009-12-10 Cuticeuticals, Inc. Topical steroid spray with botanic seed oils
AU2003225047A1 (en) * 2002-04-18 2003-11-03 Celmed Oncology (Usa), Inc. Peptide deformylase activated prodrugs
WO2003092617A2 (fr) * 2002-05-03 2003-11-13 Combinatorx, Incorporated Combinaisons destinees au traitement de troubles cutanes inflammatoires
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
WO2004037225A2 (fr) 2002-10-25 2004-05-06 Foamix Ltd. Mousse cosmetique et pharmaceutique
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US20070292461A1 (en) * 2003-08-04 2007-12-20 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
JP2006514009A (ja) 2002-11-14 2006-04-27 セルメド オンコロジー （ユーエスエイ）， インコーポレイテッド ペプチドデホルミラーゼ活性化プロドラッグ
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US20080069779A1 (en) * 2003-08-04 2008-03-20 Foamix Ltd. Foamable vehicle and vitamin and flavonoid pharmaceutical compositions thereof
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
ZA200507017B (en) * 2004-02-04 2007-03-28 Foamix Ltd Cosmetic and pharmaceutical foam with solid matter
JP2005310310A (ja) * 2004-04-23 2005-11-04 Sanyo Electric Co Ltd トラッキングバランス調整装置
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (fr) 2007-11-30 2009-06-04 Foamix Ltd. Peroxyde de benzoyle contenant de la mousse
WO2009090495A2 (fr) 2007-12-07 2009-07-23 Foamix Ltd. Vecteurs moussants siliconés à base d'huile et de liquide, et formulations
WO2010041141A2 (fr) 2008-10-07 2010-04-15 Foamix Ltd. Support expansible à base d’huile et préparations
CA2712120A1 (fr) 2008-01-14 2009-07-23 Foamix Ltd. Compositions pharmaceutiques pouvant mousser de poloxamere avec des agents actifs et/ou des cellules therapeutiques, et utilisations
WO2010125470A2 (fr) 2009-04-28 2010-11-04 Foamix Ltd. Véhicule moussant et compositions pharmaceutiques comportant des solvants polaires aprotiques et leurs utilisations
WO2011013009A2 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes non tensioactives, mousses légères, et leurs utilisations
CA2769677A1 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes a base d'agents non tensioactifs non polymeres, mousses legeres, et leurs utilisations
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
WO2011064631A1 (fr) 2009-10-02 2011-06-03 Foamix Ltd. Compositions moussantes dépourvues d'agent tensioactif et d'eau et mousses cassables et leurs utilisations
RU2559084C2 (ru) * 2009-12-22 2015-08-10 Лео Фарма А/С Фармацевтическая композиция, включающая растворяющую смесь и производное или аналог витамина d
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
ES2812451T3 (es) 2015-06-18 2021-03-17 Bausch Health Ireland Ltd Composiciones tópicas que comprenden un corticosteroide y un retinoide para tratar la psoriasis
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
TW202237137A (zh) * 2021-01-26 2022-10-01 日商塩野義醫藥保健股份有限公司 含戊酸倍他米松（ｂｅｔａｍｅｔｈａｓｏｎｅ ｖａｌｅｒａｔｅ）之軟膏劑組成物

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL267783A (fr) * 1900-01-01
FR682M (fr) * 1960-09-26 1961-07-17
FR1044M (fr) * 1960-12-20 1962-01-08 Bernard Mirande Utilisation de substances tensio-actives dans des préparations pharmaceutiques destinées aux traitements des ulcérations cutanées non infectieuses.
US3924004A (en) * 1971-11-24 1975-12-02 Syntex Corp Fatty alcohol-propylene carbonate-glycol solvent cream vehicle
US3966924A (en) * 1974-11-13 1976-06-29 Allergan Pharmaceuticals Composition and method for treating psoriasis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017615A (en) * 1970-10-29 1977-04-12 Syntex Corporation Propylene carbonate ointment vehicle
GB1404583A (en) * 1971-10-08 1975-09-03 Vymatt Sa Urea compositions and methods of preparation thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL267783A (fr) * 1900-01-01
FR682M (fr) * 1960-09-26 1961-07-17
FR1044M (fr) * 1960-12-20 1962-01-08 Bernard Mirande Utilisation de substances tensio-actives dans des préparations pharmaceutiques destinées aux traitements des ulcérations cutanées non infectieuses.
US3924004A (en) * 1971-11-24 1975-12-02 Syntex Corp Fatty alcohol-propylene carbonate-glycol solvent cream vehicle
US3966924A (en) * 1974-11-13 1976-06-29 Allergan Pharmaceuticals Composition and method for treating psoriasis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2491333A1 (fr) * 1980-10-06 1982-04-09 Glaxo Group Ltd Compositions pharmaceutiques administrables par voie topique et contenant des steroides anti-inflammatoires

Also Published As

Publication number Publication date
FR2382895B1 (fr) 1980-08-29
US4083974A (en) 1978-04-11
JPS53109934A (en) 1978-09-26
BE864645A (fr) 1978-09-07
DE2806669A1 (de) 1978-09-14
GB1547357A (en) 1979-06-13

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