ATE42895T1 - Steroide als immunomodulierende mittel. - Google Patents

Steroide als immunomodulierende mittel.

Info

Publication number
ATE42895T1
ATE42895T1 AT85200423T AT85200423T ATE42895T1 AT E42895 T1 ATE42895 T1 AT E42895T1 AT 85200423 T AT85200423 T AT 85200423T AT 85200423 T AT85200423 T AT 85200423T AT E42895 T1 ATE42895 T1 AT E42895T1
Authority
AT
Austria
Prior art keywords
sup
steroids
substituent
immunomodulating agents
oxy
Prior art date
Application number
AT85200423T
Other languages
English (en)
Inventor
Jan Kelder
Hermanus Antonius Mari Verheul
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Application granted granted Critical
Publication of ATE42895T1 publication Critical patent/ATE42895T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT85200423T 1984-03-21 1985-03-20 Steroide als immunomodulierende mittel. ATE42895T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8400888 1984-03-21
EP85200423A EP0159739B1 (de) 1984-03-21 1985-03-20 Steroide als immunomodulierende Mittel

Publications (1)

Publication Number Publication Date
ATE42895T1 true ATE42895T1 (de) 1989-05-15

Family

ID=19843679

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85200423T ATE42895T1 (de) 1984-03-21 1985-03-20 Steroide als immunomodulierende mittel.

Country Status (6)

Country Link
US (1) US4701450A (de)
EP (1) EP0159739B1 (de)
JP (1) JPS60209599A (de)
AT (1) ATE42895T1 (de)
DE (1) DE3570038D1 (de)
MX (1) MX9203811A (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0222385B1 (de) * 1985-11-13 1993-02-03 Research Development Corporation of Japan Geschlechtshormone zur Behandlung von Immun-Mangel-Krankheiten
JPH0621072B2 (ja) * 1986-11-12 1994-03-23 呉羽化学工業株式会社 エストラジオ−ル誘導体よりなる免疫調節剤
US4902681A (en) * 1987-08-27 1990-02-20 University Of Pennsylvania Inhibition of immune clearance using progesterone analogues
US4908358A (en) * 1987-08-27 1990-03-13 Trustees Of The University Of Pennsylvania Inhibition of immune clearance using progesterone analogues
IE63051B1 (en) * 1989-03-18 1995-03-22 Akzo Nv Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn- 3-one
US5342834A (en) * 1989-04-07 1994-08-30 The Population Council, Inc. Method for androgen supplementation
US5201280A (en) * 1989-06-06 1993-04-13 Reproductive Sciences, Inc. Method for preferential production of female turtles, lizards, and crocodiles
JP2683783B2 (ja) * 1992-07-10 1997-12-03 雪印乳業株式会社 シェーグレン症候群治療剤
US5639743A (en) * 1992-11-13 1997-06-17 University Of Georgia Research Foundation Compositions and methods for treating exocrine gland atrophy
DE69418744T2 (de) * 1993-03-05 1999-11-11 Akzo Nobel N.V., Arnheim/Arnhem Verwendung von Pregnanderivaten zur Behandlung von Tumoren
US5494899A (en) * 1993-04-07 1996-02-27 Oklahoma Medical Research Foundation Selective regulation of B lymphocyte precursors by hormones
IL123984A (en) * 1997-04-22 2004-09-27 Akzo Nobel Nv Pharmacological dosage units containing tibolone and carrier pharmacy are acceptable
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
CN100432093C (zh) * 1998-10-16 2008-11-12 欧加农股份有限公司 包含（7α,17α)-17-羟基-7-甲基-19-去甲-17-孕-5（10）-烯-20-炔-3-酮的高纯度组合物
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
TWI265167B (en) * 1999-11-29 2006-11-01 Akzo Nobel Nv 3-methylene steroid derivatives
US7462486B2 (en) 2000-05-12 2008-12-09 Oregon Health & Science University Methods of selecting T cell receptor V peptides for therapeutic use
US7371385B2 (en) 2000-05-12 2008-05-13 Oregon Health & Science University Method of treating immune pathologies with low dose estrogen
US20040229854A1 (en) * 2000-11-28 2004-11-18 Pieter Haan De Immediate release dosage form for HRT
GB0125061D0 (en) * 2001-10-18 2001-12-12 Norton Healthcare Ltd Pharmaceutical composition
AU2002347973A1 (en) * 2001-10-18 2003-04-28 Ivax Corporation Novel tibolone formulations
CN1324041C (zh) * 2003-04-01 2007-07-04 上海迪赛诺医药科技开发有限公司 替勃龙晶型i的制备方法
KR20050038590A (ko) * 2003-05-23 2005-04-27 엔.브이. 오가논 다형성 티볼론을 포함하는 즉시-방출형 약학 제형
WO2005120517A1 (en) * 2004-06-07 2005-12-22 Strides Arcolab Limited Stable liquid suspension formulation comprising synthetic steroids and process for producing the same
US8053197B2 (en) 2004-07-30 2011-11-08 Oregon Health & Science University Methods for detecting and treating autoimmune disorders
US8175031B2 (en) 2004-11-18 2012-05-08 Telefonaktiebolaget Lm Ericsson (Publ) Method and apparatus for supporting packet data services in service area boundary regions
EP2392258B1 (de) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-Informatiksystem
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
EP3452019B1 (de) * 2016-05-04 2021-06-23 Novalon S.A. Verwendung von zuckeralkoholen in tibolonzusammensetzungen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB885782A (en) * 1958-01-24 1961-12-28 Searle & Co Improvements in or relating to androstenone and androstanone derivatives
GB884412A (en) * 1958-09-20 1961-12-13 Organon Labor Ltd New 6-methyl-19-nor-steroids and process for the preparation thereof
US3012045A (en) * 1959-01-22 1961-12-05 Searle & Co 17alpha-alkenyl derivatives of 6alpha-methyl-17beta-hydroxy-19-nor-4-androsten-3-one
GB931009A (en) * 1959-08-17 1963-07-10 Organon Labor Ltd 6-methyl-19-nor-steroids
GB941634A (en) * 1960-11-16 1963-11-13 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
DE1250819B (de) * 1962-11-23 1967-09-28 Ciba Aktiengesellschaft, Basel (Schweiz) Verfahren zur Herstellung von 3-Hydroxy - (bzw. -Acyloxy)-7a-alkyl-19-nor-4androstenen
BE665514A (de) * 1964-06-16
BE665515A (de) * 1964-06-17
US3515719A (en) * 1967-03-15 1970-06-02 Upjohn Co 7-methyl-6,19-epoxy steroids of the androstane series
NL6901532A (de) * 1969-01-30 1970-08-03
US4412993A (en) * 1980-01-25 1983-11-01 The Upjohn Company Method of treating pseudopregnancy, galactorrhea and mastitis in mammals
US4546098A (en) * 1984-04-13 1985-10-08 The Rockefeller University Estrogen synthesis inhibitors

Also Published As

Publication number Publication date
EP0159739A1 (de) 1985-10-30
US4701450A (en) 1987-10-20
EP0159739B1 (de) 1989-05-10
MX9203811A (es) 1992-07-01
JPS60209599A (ja) 1985-10-22
DE3570038D1 (en) 1989-06-15

Similar Documents

Publication Publication Date Title
ATE42895T1 (de) Steroide als immunomodulierende mittel.
BG99261A (en) Steroid glycosides for the treatment of hyperchlesterolemia
BRPI9909908B8 (pt) conjugados de ácido graxo de sal ou ácido biliar, composição farmacêutica compreendendo os mesmos e seus usos
EA199700209A1 (ru) ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-a]ПИРИДИНА
GR900100380A (el) Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης.
DE68917884D1 (de) Phosphinsäure-Derivate von Steroiden als 5-alpha-Reduktase-Inhibitoren.
DK73594A (da) Fremgangsmåde til fremstilling af 17-substituerede 4-aza-5,7-androstadien-3-on-derivater
EA200000723A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
FI965144A0 (fi) Sterolijohdannaiset käytettäviksi meioosin säätelyyn
NZ222399A (en) Cephalosporin derivatives; pharmaceutical compositions and processes for preparation
PH25130A (en) 4-acylphenoxy derivatives as anti-inflammatory agents
ES8404361A1 (es) Un procedimiento para la preparacion de un derivado de cefalosporina.
DK282784D0 (da) 1-alkyl-androsta-1,4-dien-3,17-dioner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater indeholdende dem
ATE110736T1 (de) Phosphonsäure-derivate von steroiden als hemmstoffe der 5-alpha-reduktase.
ATE90355T1 (de) Weiche steroide mit anti-entzuendungswirkung.
ES2055235T3 (es) Composicion anti-inflamatoria y/o antialergica que comprende derivados de glutation.
FR2361879A2 (fr) Nouvelles 4,5,6,7- tetrahydro-7-oxo (ou hydroxy)benzo (b)thienyl-4-amines utiles notamment comme agents de croissance pour animaux et leur procede de preparation
DE69612056D1 (de) Terpenderivate (sarcodictyine) als antikrebsmittel
ES2016464A6 (es) Procedimiento para preparar derivados de 2', 5' -oligoadenilato.
FI873574A0 (fi) Platinaderivat.
FR2397427A1 (fr) Derives de steroide et leur procede de preparation
ATE94397T1 (de) Kombinationspraeparate enthaltend chloramphenicol, gentamicin und nystatin als aktive wirkstoffe zur topischen behandlung entzuendlicher hauterkrankungen.
ES2179206T3 (es) Derivados de 12h-dibenzo(d,g)(1,3)dioxocina.
SE8506015D0 (sv) Novel 16,17-acetalsubstituted pregnane 21-oic acid derivatives
DK515486A (da) 1-methyl-15alfa-alkyl-androsta-1,4-dien-3,17-dioner, fremgangsmaade tilfremstilling deraf og farmaceutiske praeparater der indeholder disse

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee