FR2376860A1 - Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique - Google Patents

Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique

Info

Publication number
FR2376860A1
FR2376860A1 FR7700408A FR7700408A FR2376860A1 FR 2376860 A1 FR2376860 A1 FR 2376860A1 FR 7700408 A FR7700408 A FR 7700408A FR 7700408 A FR7700408 A FR 7700408A FR 2376860 A1 FR2376860 A1 FR 2376860A1
Authority
FR
France
Prior art keywords
thieno
tetrahydro
pyridines
preparation process
therapeutic application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7700408A
Other languages
English (en)
French (fr)
Other versions
FR2376860B1 (US08197722-20120612-C00042.png
Inventor
Jean-Pierre Maffrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parcor SARL
Original Assignee
Parcor SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parcor SARL filed Critical Parcor SARL
Priority to FR7700408A priority Critical patent/FR2376860A1/fr
Priority to YU3040/77A priority patent/YU40023B/xx
Priority to US05/864,939 priority patent/US4147787A/en
Priority to IL53708A priority patent/IL53708A/xx
Priority to IE2655/77A priority patent/IE46288B1/en
Priority to SE7714940A priority patent/SE421922B/sv
Priority to NLAANVRAGE7800034,A priority patent/NL184220C/xx
Priority to GB68/78A priority patent/GB1574394A/en
Priority to HU78PA1299A priority patent/HU175645B/hu
Priority to CA294,348A priority patent/CA1087187A/en
Priority to AT6178A priority patent/AT357532B/de
Priority to ZA00780033A priority patent/ZA7833B/xx
Priority to CH7178A priority patent/CH631179A5/fr
Priority to GR55094A priority patent/GR66061B/el
Priority to LU78816A priority patent/LU78816A1/xx
Priority to ES465683A priority patent/ES465683A1/es
Priority to DD7800203109A priority patent/DD133673A5/xx
Priority to AR270641A priority patent/AR217668A1/es
Priority to BE184146A priority patent/BE862695A/xx
Priority to MX786754U priority patent/MX5274E/es
Priority to NZ186168A priority patent/NZ186168A/xx
Priority to PL1978203863A priority patent/PL118048B1/pl
Priority to DK7578A priority patent/DK147826C/da
Priority to AU32238/78A priority patent/AU508277B2/en
Priority to NO780050A priority patent/NO780050L/no
Priority to FI780048A priority patent/FI62308C/fi
Priority to PT67501A priority patent/PT67501B/pt
Priority to SU782562904A priority patent/SU683625A3/ru
Priority to JP53000787A priority patent/JPS6040436B2/ja
Priority to DE2800596A priority patent/DE2800596C2/de
Priority to PH20633A priority patent/PH12856A/en
Publication of FR2376860A1 publication Critical patent/FR2376860A1/fr
Application granted granted Critical
Publication of FR2376860B1 publication Critical patent/FR2376860B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7700408A 1977-01-07 1977-01-07 Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique Granted FR2376860A1 (fr)

Priority Applications (31)

Application Number Priority Date Filing Date Title
FR7700408A FR2376860A1 (fr) 1977-01-07 1977-01-07 Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique
YU3040/77A YU40023B (en) 1977-01-07 1977-12-22 Process for obtaining tetrahydro-4,5,6,7-thieno-(2,3-c)and (3,2-c)pyridines
US05/864,939 US4147787A (en) 1977-01-07 1977-12-27 4,5,6,7-Tetrahydro-thieno[2,3-c]-and [3,2-c]-pyridines, and therapeutic compositions containing the same
IL53708A IL53708A (en) 1977-01-07 1977-12-28 4,5,6,7-tetrahydrothieno(2,3-c)pyridine-5-carboxylic (3,2-c)pyridine-6-carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
IE2655/77A IE46288B1 (en) 1977-01-07 1977-12-30 Improvements in or relating to 4,5,6,7-tetrahydrothieno (28,3-c)-and(3,2-c)pyridines,process for their preparation and their applications
SE7714940A SE421922B (sv) 1977-01-07 1977-12-30 Forfarande for framstellning av derivat av 5-karboxi-(respektive 6-karboxi)4,5,6,7,-tetrahydro-tieno(2,3-c)-(respektive(3,2-c)-)pyridin
NLAANVRAGE7800034,A NL184220C (nl) 1977-01-07 1978-01-02 4,5,6,7-tetrahydrothieno (2,3-c) en (3,2-c)pyridinederivaten met anti-trombose, anti-aggratie van bloedplaatjes en anti-verkleving van erythrocyten werking, werkwijze ter bereiding daarvan en farmaceutische preparaten die ze bevatten.
GB68/78A GB1574394A (en) 1977-01-07 1978-01-03 4,5,6,7-tetrahydro-thieon(2,3 - c)- and (3,2 - c)pyridines process for their preparation and their applications
HU78PA1299A HU175645B (hu) 1977-01-07 1978-01-03 Sposob poluchenija 4,5,6,7-tetragidro-tieno/2,3-c/-i-/3,2-c/piridina
AT6178A AT357532B (de) 1977-01-07 1978-01-04 Verfahren zur herstellung von neuen 4,5,6,7- tetrahydrothieno (2,3-c)- und-(3,2-c)pyridinen und von deren salzen
ZA00780033A ZA7833B (en) 1977-01-07 1978-01-04 4,5,6,7-tetrahydro-thieno(2,3-c)and(3,2-c)-pyridines,process for their preparation and their applications
CH7178A CH631179A5 (fr) 1977-01-07 1978-01-04 Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines et leur procede de preparation.
GR55094A GR66061B (US08197722-20120612-C00042.png) 1977-01-07 1978-01-04
CA294,348A CA1087187A (en) 1977-01-07 1978-01-04 Process for the preparation of 4,5,6,7-tetrahydro- thieno 2,3-c - and 3,2-c pyridines
AR270641A AR217668A1 (es) 1977-01-07 1978-01-05 Procedimiento de preparacion de derivados de tetrahidro-4,5,6,7-tieno-(2,3-c)-y-(3,2-c)-piridinas,utilizables como medicamentos
DD7800203109A DD133673A5 (de) 1977-01-07 1978-01-05 Verfahren zur herstellung von 4,5,6,7-tetrahydrothieno(2,3-c)-und-(3,2-c)pyridinen
LU78816A LU78816A1 (fr) 1977-01-07 1978-01-05 Procede de preparation de tetrahydro-4,5,6,7 thieno(2,3-c)et(3,2-c)pyridines
ES465683A ES465683A1 (es) 1977-01-07 1978-01-05 Un procedimiento de preparacion de derivados de tetrahidro- 4,5,6,7-tieno-(2,3,c)-y-(3,2-c)-piridinas.
SU782562904A SU683625A3 (ru) 1977-01-07 1978-01-06 Способ получени 4,5,6,7-тетрагидротиено-(2,3-с)-или-(3,2-с)-пиридинов или их солей
NZ186168A NZ186168A (en) 1977-01-07 1978-01-06 4,5,6,7-tetrahydr-thieno(2,3-c)and (3,2-c) pyridines and pharmaceutical compositions
PL1978203863A PL118048B1 (en) 1977-01-07 1978-01-06 Process for preparing novel 4,5,6,7-tetrahydrothieno/2,3-c/and/3,2-c/pyridineseh/i/3,2-ceh/piridinov
DK7578A DK147826C (da) 1977-01-07 1978-01-06 Fremgangsmaade til fremstilling af 4,5,6,7-tetrahydro-thieno(2,3-c)- eller -(3,2-c)pyridiner
AU32238/78A AU508277B2 (en) 1977-01-07 1978-01-06 Parcor
NO780050A NO780050L (no) 1977-01-07 1978-01-06 Fremgangsmaate ved fremstilling av 4,5,6,7-tetrahydrothieno-(2,3-c) og (3,2-c)pyridiner
BE184146A BE862695A (fr) 1977-01-07 1978-01-06 Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leurs applications
PT67501A PT67501B (fr) 1977-01-07 1978-01-06 Procede de preparation de derives de tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines
MX786754U MX5274E (es) 1977-01-07 1978-01-06 Procedimiento de preparacion de derivados de tetrahidro-4,5,6,7-tieno-(2,3-c)-y(3,2-c)-piridinas
FI780048A FI62308C (fi) 1977-01-07 1978-01-06 Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-ller 6-karboxiderivat av 4,5,6,7-tetrahydro(2,3-c)- och 3,-(-c)pyridiner
JP53000787A JPS6040436B2 (ja) 1977-01-07 1978-01-07 ４，５，６，７‐テトラヒドロ‐チエノ〔２，３‐ｃ〕‐及び〔３，２‐ｃ〕ピリジン誘導体、その製造方法及び治療用組成物
DE2800596A DE2800596C2 (de) 1977-01-07 1978-01-07 4,5,6,7-Tetrahydrothieno(2,3-c)- und -(3,2-c)pyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
PH20633A PH12856A (en) 1977-01-07 1978-01-09 4,5,6,7-tetrahydro-thieno(2,3-c)and(3,2-c)pyridines and therapeutic composition thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7700408A FR2376860A1 (fr) 1977-01-07 1977-01-07 Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique

Publications (2)

Publication Number Publication Date
FR2376860A1 true FR2376860A1 (fr) 1978-08-04
FR2376860B1 FR2376860B1 (US08197722-20120612-C00042.png) 1979-04-20

Family

ID=9185247

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7700408A Granted FR2376860A1 (fr) 1977-01-07 1977-01-07 Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique

Country Status (31)

Country Link
US (1) US4147787A (US08197722-20120612-C00042.png)
JP (1) JPS6040436B2 (US08197722-20120612-C00042.png)
AR (1) AR217668A1 (US08197722-20120612-C00042.png)
AT (1) AT357532B (US08197722-20120612-C00042.png)
AU (1) AU508277B2 (US08197722-20120612-C00042.png)
BE (1) BE862695A (US08197722-20120612-C00042.png)
CA (1) CA1087187A (US08197722-20120612-C00042.png)
CH (1) CH631179A5 (US08197722-20120612-C00042.png)
DD (1) DD133673A5 (US08197722-20120612-C00042.png)
DE (1) DE2800596C2 (US08197722-20120612-C00042.png)
DK (1) DK147826C (US08197722-20120612-C00042.png)
ES (1) ES465683A1 (US08197722-20120612-C00042.png)
FI (1) FI62308C (US08197722-20120612-C00042.png)
FR (1) FR2376860A1 (US08197722-20120612-C00042.png)
GB (1) GB1574394A (US08197722-20120612-C00042.png)
GR (1) GR66061B (US08197722-20120612-C00042.png)
HU (1) HU175645B (US08197722-20120612-C00042.png)
IE (1) IE46288B1 (US08197722-20120612-C00042.png)
IL (1) IL53708A (US08197722-20120612-C00042.png)
LU (1) LU78816A1 (US08197722-20120612-C00042.png)
MX (1) MX5274E (US08197722-20120612-C00042.png)
NL (1) NL184220C (US08197722-20120612-C00042.png)
NO (1) NO780050L (US08197722-20120612-C00042.png)
NZ (1) NZ186168A (US08197722-20120612-C00042.png)
PH (1) PH12856A (US08197722-20120612-C00042.png)
PL (1) PL118048B1 (US08197722-20120612-C00042.png)
PT (1) PT67501B (US08197722-20120612-C00042.png)
SE (1) SE421922B (US08197722-20120612-C00042.png)
SU (1) SU683625A3 (US08197722-20120612-C00042.png)
YU (1) YU40023B (US08197722-20120612-C00042.png)
ZA (1) ZA7833B (US08197722-20120612-C00042.png)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA743814B (en) * 1973-06-15 1976-01-28 Merck & Co Inc Mercaptoalkylpyridines and derivatives
US4400384A (en) * 1980-10-06 1983-08-23 Sanofi, S.A. 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-c] pyridine methanesulfonate and other novel salts thereof
US4448779A (en) * 1981-07-16 1984-05-15 Sanofi Use of MS salt in geriatric medicine
US4775757A (en) * 1986-09-22 1988-10-04 Ortho Pharmaceutical Corporation Thienopyridines useful as cardiovascular agents
US4906756A (en) * 1988-05-10 1990-03-06 Syntex (U.S.A.) Inc. 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives
US5342953A (en) * 1991-01-31 1994-08-30 Syntex (U.S.A.) Inc. N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom
EP0581250B1 (de) * 1992-07-31 1999-03-03 Hoechst Aktiengesellschaft Verfahren zur Biotechnischen Herstellung von L-Thienylalaninen in enantiomerenreiner Form aus 2-Hydroxy-3-thienyl-acrylsäuren und ihre Verwendung
FR2710495B1 (fr) * 1993-09-28 1995-10-27 Celaflor Gmbh Dispositif pour effectuer des traitements insecticides, et leur utilisation dans les habitations.
HUT72440A (en) 1994-03-31 1996-04-29 Bristol Myers Squibb Co Imidazole-containing inhibitors of farnesyl protein transferase and pharmaceutical compositions containing them
WO2000001364A1 (en) * 1998-07-01 2000-01-13 Sun Pharmaceutical Industries Ltd. Stable pharmaceutical compositions of thieno [3,2-c] pyridine derivatives
US6323215B1 (en) 1999-07-09 2001-11-27 Ortho-Mcneil Pharmaceutical, Inc. Neurotrophic tetrahydroisoquinolines and tetrahydrothienopyridines, and related compositions and methods
BR0116531A (pt) * 2000-12-25 2004-02-25 Sankyo Co Composição farmacêutica, kit e uso de um composto

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2215948A1 (US08197722-20120612-C00042.png) * 1973-02-01 1974-08-30 Centre Etd Ind Pharma
FR2312247A1 (fr) * 1975-05-30 1976-12-24 Parcor Derives de la thieno-pyridine, leur procede de preparation et leurs applications

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3823151A (en) * 1968-08-02 1974-07-09 Ciba Geigy Corp 4,5,6,7-tetrahydrothieno(2,3-d)pyridines
US3997545A (en) * 1973-07-23 1976-12-14 Takeda Chemical Industries, Ltd. Thienopyridine-carboxylic acid derivatives
FR2312246A1 (fr) * 1975-05-28 1976-12-24 Parcor Derives de la tetrahydro-4,5,6,7 thieno (3,2-c) pyridine, leur procede de preparation et leurs applications

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2215948A1 (US08197722-20120612-C00042.png) * 1973-02-01 1974-08-30 Centre Etd Ind Pharma
FR2312247A1 (fr) * 1975-05-30 1976-12-24 Parcor Derives de la thieno-pyridine, leur procede de preparation et leurs applications

Also Published As

Publication number Publication date
YU40023B (en) 1985-06-30
SE421922B (sv) 1982-02-08
NL184220C (nl) 1989-05-16
DK147826C (da) 1985-06-10
IE46288B1 (en) 1983-04-20
AU3223878A (en) 1979-07-12
CH631179A5 (fr) 1982-07-30
AT357532B (de) 1980-07-10
GR66061B (US08197722-20120612-C00042.png) 1981-01-15
DD133673A5 (de) 1979-01-17
IL53708A0 (en) 1978-03-10
ES465683A1 (es) 1978-10-01
FR2376860B1 (US08197722-20120612-C00042.png) 1979-04-20
PT67501B (fr) 1979-06-11
MX5274E (es) 1983-05-31
FI62308B (fi) 1982-08-31
DE2800596C2 (de) 1985-12-12
FI62308C (fi) 1982-12-10
JPS5387394A (en) 1978-08-01
JPS6040436B2 (ja) 1985-09-11
DK147826B (da) 1984-12-17
HU175645B (hu) 1980-09-28
FI780048A (fi) 1978-07-08
AU508277B2 (en) 1980-03-13
DK7578A (da) 1978-07-08
SE7714940L (sv) 1978-07-08
PL203863A1 (pl) 1979-03-26
NZ186168A (en) 1979-10-25
LU78816A1 (fr) 1978-06-09
ATA6178A (de) 1979-12-15
SU683625A3 (ru) 1979-08-30
DE2800596A1 (de) 1978-07-13
YU304077A (en) 1982-08-31
ZA7833B (en) 1978-11-29
NO780050L (no) 1978-07-10
GB1574394A (en) 1980-09-03
IL53708A (en) 1980-09-16
US4147787A (en) 1979-04-03
NL7800034A (nl) 1978-07-11
IE46288L (en) 1978-07-07
PH12856A (en) 1979-09-12
PT67501A (fr) 1978-02-01
NL184220B (nl) 1988-12-16
CA1087187A (en) 1980-10-07
AR217668A1 (es) 1980-04-15
PL118048B1 (en) 1981-09-30
BE862695A (fr) 1978-07-06

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