FR2373534A1 - Nouveau procede de preparation de derives de la quinazolinone - Google Patents

Nouveau procede de preparation de derives de la quinazolinone

Info

Publication number
FR2373534A1
FR2373534A1 FR7736661A FR7736661A FR2373534A1 FR 2373534 A1 FR2373534 A1 FR 2373534A1 FR 7736661 A FR7736661 A FR 7736661A FR 7736661 A FR7736661 A FR 7736661A FR 2373534 A1 FR2373534 A1 FR 2373534A1
Authority
FR
France
Prior art keywords
preparation
new process
quinazolinone derivatives
quinazolinone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7736661A
Other languages
English (en)
Other versions
FR2373534B1 (fr
Inventor
Guido Gamboni
Walter Schmid
Alfred Sutter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2373534A1 publication Critical patent/FR2373534A1/fr
Application granted granted Critical
Publication of FR2373534B1 publication Critical patent/FR2373534B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80—Oxygen atoms
    • C07D239/82—Oxygen atoms with an aryl radical attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

L'invention concerne un nouveau procédé de préparation de 4-phényl-2(1H)-quinazolinones. Selon le procédé de l'invention, on cyclise les 2-amino-benzophénones correspondantes avec l'urée ou un carbamate d'alkyle, en présence d'un acide aromatique. L'invention s'applique à la préparation de substances actives de médicaments.
FR7736661A 1976-12-13 1977-12-06 Nouveau procede de preparation de derives de la quinazolinone Granted FR2373534A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1561976A CH625512A5 (fr) 1976-12-13 1976-12-13

Publications (2)

Publication Number Publication Date
FR2373534A1 true FR2373534A1 (fr) 1978-07-07
FR2373534B1 FR2373534B1 (fr) 1983-01-14

Family

ID=4410585

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7736661A Granted FR2373534A1 (fr) 1976-12-13 1977-12-06 Nouveau procede de preparation de derives de la quinazolinone

Country Status (31)

Country Link
US (1) US4236006A (fr)
JP (1) JPS5377077A (fr)
AR (1) AR220526A1 (fr)
AT (1) AT371450B (fr)
AU (1) AU517193B2 (fr)
BE (1) BE861775A (fr)
CA (1) CA1091229A (fr)
CH (1) CH625512A5 (fr)
CS (1) CS196409B2 (fr)
DD (1) DD133327A5 (fr)
DE (1) DE2753970A1 (fr)
DK (1) DK143025C (fr)
ES (1) ES464966A1 (fr)
FI (1) FI64358C (fr)
FR (1) FR2373534A1 (fr)
GB (1) GB1592687A (fr)
GR (1) GR71667B (fr)
HU (1) HU176875B (fr)
IE (1) IE46492B1 (fr)
IL (1) IL53588A (fr)
IT (1) IT1090572B (fr)
NL (1) NL7713651A (fr)
NO (1) NO147484C (fr)
NZ (1) NZ185933A (fr)
OA (1) OA05821A (fr)
PH (1) PH15458A (fr)
PT (1) PT67388B (fr)
SE (1) SE442996B (fr)
SU (1) SU793391A3 (fr)
YU (1) YU40687B (fr)
ZA (1) ZA777425B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4617392A (en) * 1983-09-29 1986-10-14 Ortho Pharmaceutical Corporation 4-alkyl-5,6-methylenedioxy-2-1[H]-quinazolinones useful as cardiotonic agents
AR038658A1 (es) * 2001-06-15 2005-01-26 Novartis Ag Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento
GB0230015D0 (en) * 2002-12-23 2003-01-29 Novartis Ag Organic compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2135314A2 (fr) * 1971-05-06 1972-12-15 Sandoz Sa
CH580083A5 (en) * 1973-04-03 1976-09-30 Sumitomo Chemical Co 4-Aryl-2-(1H)-quinazolinones prepn - by hydrolysis or thermolysis of 2-(acylureido)-benzophenones

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3547921A (en) * 1968-12-26 1970-12-15 Sandoz Ag Preparation of 1-substituted-4-aryl-3,4-dihydro-2(1h)-quinazolinones
US3642897A (en) * 1968-12-26 1972-02-15 Sandoz Ag Preparation of 2-alkylaminobenzophenones
US3551427A (en) * 1969-05-09 1970-12-29 Sandoz Ag 4-thienyl-2-(1h)-quinazolones
BE790804A (fr) * 1971-11-18 1973-04-30 Sandoz Sa Procede de preparation de derives de la quinazoline

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2135314A2 (fr) * 1971-05-06 1972-12-15 Sandoz Sa
CH580083A5 (en) * 1973-04-03 1976-09-30 Sumitomo Chemical Co 4-Aryl-2-(1H)-quinazolinones prepn - by hydrolysis or thermolysis of 2-(acylureido)-benzophenones

Also Published As

Publication number Publication date
AR220526A1 (es) 1980-11-14
CS196409B2 (en) 1980-03-31
ZA777425B (en) 1979-07-25
CA1091229A (fr) 1980-12-09
YU40687B (en) 1986-04-30
DK143025B (da) 1981-03-16
CH625512A5 (fr) 1981-09-30
DD133327A5 (de) 1978-12-27
PT67388B (en) 1979-09-20
NO147484C (no) 1983-04-20
JPS5377077A (en) 1978-07-08
ATA884677A (de) 1982-11-15
IE46492B1 (en) 1983-06-29
SE7713742L (sv) 1978-06-14
IT1090572B (it) 1985-06-26
FR2373534B1 (fr) 1983-01-14
HU176875B (en) 1981-05-28
DK143025C (da) 1981-09-28
OA05821A (fr) 1981-05-31
FI64358C (fi) 1983-11-10
SE442996B (sv) 1986-02-10
JPS6143349B2 (fr) 1986-09-26
NZ185933A (en) 1980-11-14
DK540877A (da) 1978-06-14
FI64358B (fi) 1983-07-29
AU3143877A (en) 1979-06-21
PT67388A (en) 1978-01-01
AU517193B2 (en) 1981-07-16
AT371450B (de) 1983-06-27
SU793391A3 (ru) 1980-12-30
BE861775A (fr) 1978-06-12
YU294577A (en) 1982-06-30
GR71667B (fr) 1983-06-20
DE2753970A1 (de) 1978-06-15
IL53588A (en) 1981-11-30
PH15458A (en) 1983-01-18
ES464966A1 (es) 1979-01-01
NO147484B (no) 1983-01-10
FI773659A (fi) 1978-06-14
US4236006A (en) 1980-11-25
NL7713651A (nl) 1978-06-15
GB1592687A (en) 1981-07-08
IE46492L (en) 1978-06-13
IL53588A0 (en) 1978-03-10
NO774147L (no) 1978-06-14

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Legal Events

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