ES464966A1 - Un procedimiento para la produccion de 4-fenil-2(1h)-quina- zolinonas - Google Patents
Un procedimiento para la produccion de 4-fenil-2(1h)-quina- zolinonasInfo
- Publication number
- ES464966A1 ES464966A1 ES464966A ES464966A ES464966A1 ES 464966 A1 ES464966 A1 ES 464966A1 ES 464966 A ES464966 A ES 464966A ES 464966 A ES464966 A ES 464966A ES 464966 A1 ES464966 A1 ES 464966A1
- Authority
- ES
- Spain
- Prior art keywords
- quinazolin
- ones
- preparation
- alkylcarbamate
- quinazolinones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AVRPFRMDMNDIDH-UHFFFAOYSA-N 1h-quinazolin-2-one Chemical class C1=CC=CC2=NC(O)=NC=C21 AVRPFRMDMNDIDH-UHFFFAOYSA-N 0.000 title 1
- MAOBFOXLCJIFLV-UHFFFAOYSA-N (2-aminophenyl)-phenylmethanone Chemical compound NC1=CC=CC=C1C(=O)C1=CC=CC=C1 MAOBFOXLCJIFLV-UHFFFAOYSA-N 0.000 abstract 1
- FHUBTSLLILWICW-UHFFFAOYSA-N 4-phenyl-1h-quinazolin-2-one Chemical class C12=CC=CC=C2NC(=O)N=C1C1=CC=CC=C1 FHUBTSLLILWICW-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
- C07D239/82—Oxygen atoms with an aryl radical attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Un procedimiento para la producción de 4-fenil-2(1H)- quinazolinonas, caracterizado porque se ciclizan 2- aminobenzofenonas con urea o con carbamato de alquilo en presencia de un ácido aromático.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1561976A CH625512A5 (es) | 1976-12-13 | 1976-12-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES464966A1 true ES464966A1 (es) | 1979-01-01 |
Family
ID=4410585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES464966A Expired ES464966A1 (es) | 1976-12-13 | 1977-12-12 | Un procedimiento para la produccion de 4-fenil-2(1h)-quina- zolinonas |
Country Status (31)
Country | Link |
---|---|
US (1) | US4236006A (es) |
JP (1) | JPS5377077A (es) |
AR (1) | AR220526A1 (es) |
AT (1) | AT371450B (es) |
AU (1) | AU517193B2 (es) |
BE (1) | BE861775A (es) |
CA (1) | CA1091229A (es) |
CH (1) | CH625512A5 (es) |
CS (1) | CS196409B2 (es) |
DD (1) | DD133327A5 (es) |
DE (1) | DE2753970A1 (es) |
DK (1) | DK143025C (es) |
ES (1) | ES464966A1 (es) |
FI (1) | FI64358C (es) |
FR (1) | FR2373534A1 (es) |
GB (1) | GB1592687A (es) |
GR (1) | GR71667B (es) |
HU (1) | HU176875B (es) |
IE (1) | IE46492B1 (es) |
IL (1) | IL53588A (es) |
IT (1) | IT1090572B (es) |
NL (1) | NL7713651A (es) |
NO (1) | NO147484C (es) |
NZ (1) | NZ185933A (es) |
OA (1) | OA05821A (es) |
PH (1) | PH15458A (es) |
PT (1) | PT67388B (es) |
SE (1) | SE442996B (es) |
SU (1) | SU793391A3 (es) |
YU (1) | YU40687B (es) |
ZA (1) | ZA777425B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4617392A (en) * | 1983-09-29 | 1986-10-14 | Ortho Pharmaceutical Corporation | 4-alkyl-5,6-methylenedioxy-2-1[H]-quinazolinones useful as cardiotonic agents |
AR038658A1 (es) * | 2001-06-15 | 2005-01-26 | Novartis Ag | Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento |
GB0230015D0 (en) * | 2002-12-23 | 2003-01-29 | Novartis Ag | Organic compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3547921A (en) * | 1968-12-26 | 1970-12-15 | Sandoz Ag | Preparation of 1-substituted-4-aryl-3,4-dihydro-2(1h)-quinazolinones |
US3642897A (en) * | 1968-12-26 | 1972-02-15 | Sandoz Ag | Preparation of 2-alkylaminobenzophenones |
US3551427A (en) * | 1969-05-09 | 1970-12-29 | Sandoz Ag | 4-thienyl-2-(1h)-quinazolones |
DK135044B (da) * | 1971-05-06 | 1977-02-28 | Sandoz Ag | Analogifremgangsmåde til fremstilling af 4-phenyl- eller 4-(2'-thienyl)-6,7-methylendioxy-2(1H)-quinazolinoner eller -2(1H)-quinazolinthioner. |
BE790804A (fr) * | 1971-11-18 | 1973-04-30 | Sandoz Sa | Procede de preparation de derives de la quinazoline |
CH580083A5 (en) * | 1973-04-03 | 1976-09-30 | Sumitomo Chemical Co | 4-Aryl-2-(1H)-quinazolinones prepn - by hydrolysis or thermolysis of 2-(acylureido)-benzophenones |
-
1976
- 1976-12-13 CH CH1561976A patent/CH625512A5/de not_active IP Right Cessation
-
1977
- 1977-12-02 FI FI773659A patent/FI64358C/fi not_active IP Right Cessation
- 1977-12-03 DE DE19772753970 patent/DE2753970A1/de not_active Withdrawn
- 1977-12-05 NO NO774147A patent/NO147484C/no unknown
- 1977-12-05 DK DK540877A patent/DK143025C/da not_active IP Right Cessation
- 1977-12-05 SE SE7713742A patent/SE442996B/sv not_active IP Right Cessation
- 1977-12-06 FR FR7736661A patent/FR2373534A1/fr active Granted
- 1977-12-08 GB GB51144/77A patent/GB1592687A/en not_active Expired
- 1977-12-09 CA CA292,750A patent/CA1091229A/en not_active Expired
- 1977-12-09 NL NL7713651A patent/NL7713651A/xx not_active Application Discontinuation
- 1977-12-10 GR GR54959A patent/GR71667B/el unknown
- 1977-12-12 OA OA56337A patent/OA05821A/xx unknown
- 1977-12-12 JP JP14823077A patent/JPS5377077A/ja active Granted
- 1977-12-12 IE IE2518/77A patent/IE46492B1/en unknown
- 1977-12-12 IL IL53588A patent/IL53588A/xx unknown
- 1977-12-12 ES ES464966A patent/ES464966A1/es not_active Expired
- 1977-12-12 DD DD7700202556A patent/DD133327A5/xx unknown
- 1977-12-12 BE BE183388A patent/BE861775A/xx not_active IP Right Cessation
- 1977-12-12 AT AT0884677A patent/AT371450B/de not_active IP Right Cessation
- 1977-12-12 AU AU31438/77A patent/AU517193B2/en not_active Expired
- 1977-12-12 HU HU77SA3080A patent/HU176875B/hu not_active IP Right Cessation
- 1977-12-12 CS CS778309A patent/CS196409B2/cs unknown
- 1977-12-12 NZ NZ185933A patent/NZ185933A/xx unknown
- 1977-12-12 SU SU772552353A patent/SU793391A3/ru active
- 1977-12-12 AR AR270333A patent/AR220526A1/es active
- 1977-12-12 PT PT67388A patent/PT67388B/pt unknown
- 1977-12-12 PH PH20542A patent/PH15458A/en unknown
- 1977-12-13 YU YU2945/77A patent/YU40687B/xx unknown
- 1977-12-13 ZA ZA00777425A patent/ZA777425B/xx unknown
- 1977-12-13 IT IT52191/77A patent/IT1090572B/it active
-
1979
- 1979-02-01 US US06/008,328 patent/US4236006A/en not_active Expired - Lifetime
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