FR2372157A1 - Procede de synthese stereospecifique de n-alkyl- pyrrolidines optiquement actives - Google Patents

Procede de synthese stereospecifique de n-alkyl- pyrrolidines optiquement actives

Info

Publication number
FR2372157A1
FR2372157A1 FR7635476A FR7635476A FR2372157A1 FR 2372157 A1 FR2372157 A1 FR 2372157A1 FR 7635476 A FR7635476 A FR 7635476A FR 7635476 A FR7635476 A FR 7635476A FR 2372157 A1 FR2372157 A1 FR 2372157A1
Authority
FR
France
Prior art keywords
pyrrolidine
methyl
intermediates
optically active
derivs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7635476A
Other languages
English (en)
French (fr)
Other versions
FR2372157B1 (OSRAM
Inventor
Jean Pierre Kaplan
Henry Najer
Daniel Charles Leon Dbitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7635476A priority Critical patent/FR2372157A1/fr
Priority to IL52645A priority patent/IL52645A/xx
Priority to NL7708571A priority patent/NL7708571A/xx
Priority to NZ184832A priority patent/NZ184832A/xx
Priority to GR54101A priority patent/GR63594B/el
Priority to DE2735036A priority patent/DE2735036C2/de
Priority to IT26497/77A priority patent/IT1085696B/it
Priority to DK350377A priority patent/DK350377A/da
Priority to FI772363A priority patent/FI772363A7/fi
Priority to LU77917A priority patent/LU77917A1/xx
Priority to SE7708902A priority patent/SE7708902L/xx
Priority to IE1633/77A priority patent/IE45544B1/en
Priority to GB32790/77A priority patent/GB1555890A/en
Priority to AU27641/77A priority patent/AU510454B2/en
Priority to NO772745A priority patent/NO772745L/no
Priority to ES461342A priority patent/ES461342A1/es
Priority to CH959477A priority patent/CH624933A5/fr
Priority to JP9404477A priority patent/JPS5325563A/ja
Priority to CA284,104A priority patent/CA1083586A/en
Priority to PT66894A priority patent/PT66894B/pt
Priority to AT0577377A priority patent/AT364818B/de
Publication of FR2372157A1 publication Critical patent/FR2372157A1/fr
Application granted granted Critical
Publication of FR2372157B1 publication Critical patent/FR2372157B1/fr
Priority to AT281580A priority patent/AT364819B/de
Priority to SE8009074A priority patent/SE8009074L/sv
Priority to CH4181A priority patent/CH626341A5/fr
Priority to NO812871A priority patent/NO812871L/no
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
FR7635476A 1976-08-05 1976-11-25 Procede de synthese stereospecifique de n-alkyl- pyrrolidines optiquement actives Granted FR2372157A1 (fr)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR7635476A FR2372157A1 (fr) 1976-11-25 1976-11-25 Procede de synthese stereospecifique de n-alkyl- pyrrolidines optiquement actives
IL52645A IL52645A (en) 1976-08-05 1977-08-02 Optically active 1 substituted 2 aminomethyl pyrrolidines stereospecifics synthesis thereof and process for the preparation of optically active 2 methoxy n pyrrolidylmethyl benzamides
NZ184832A NZ184832A (en) 1976-08-05 1977-08-03 Optically active n-substituted pyrrolidines
GR54101A GR63594B (en) 1976-08-05 1977-08-03 Method for pyrrolidines composition of specific stereoisomeusm arrangement
DE2735036A DE2735036C2 (de) 1976-08-05 1977-08-03 Verfahren zur Herstellung optisch aktiver, N-substituierter Pyrrolidine
NL7708571A NL7708571A (nl) 1976-08-05 1977-08-03 Werkwijze voor de stereospecifieke bereiding van optisch actieve pyrrolidineverbindingen.
JP9404477A JPS5325563A (en) 1976-08-05 1977-08-04 Stereospecific method of preparation of nnsubstituted pyrrolidines
FI772363A FI772363A7 (OSRAM) 1976-08-05 1977-08-04
LU77917A LU77917A1 (OSRAM) 1976-08-05 1977-08-04
SE7708902A SE7708902L (sv) 1976-08-05 1977-08-04 Stereospecifik syntes av n-substituerade pyrrolidiner
IE1633/77A IE45544B1 (en) 1976-08-05 1977-08-04 Aptically active n-substituted pyrrolidines
GB32790/77A GB1555890A (en) 1976-08-05 1977-08-04 Optically active n substituted pyrrolidines
IT26497/77A IT1085696B (it) 1976-08-05 1977-08-04 Sintesi stereospecifica di pirrolidine n-sostituite
NO772745A NO772745L (no) 1976-08-05 1977-08-04 Fremgangsm}te for fremstilling av n-substituerte pyrrolidiner
ES461342A ES461342A1 (es) 1976-08-05 1977-08-04 Procedimiento de sintesis estereoespecifica de pirrolidinas opticamente activas.
CH959477A CH624933A5 (OSRAM) 1976-08-05 1977-08-04
DK350377A DK350377A (da) 1976-08-05 1977-08-04 Fremgangsmade til stereospecifik fremstilling af optisk aktive n-substituerede pyrrolidiner
CA284,104A CA1083586A (en) 1976-08-05 1977-08-04 Stereospecific synthesis of pyrrolidines
PT66894A PT66894B (fr) 1976-08-05 1977-08-04 Procede de synthese stereospecifique de pyrrolidines n-substituees
AU27641/77A AU510454B2 (en) 1976-08-05 1977-08-04 N-substituted pyrrolidines
AT0577377A AT364818B (de) 1976-08-05 1977-08-05 Verfahren zur stereospezifischen synthese von optisch aktiven, n-substituierten pyrrolidinen
AT281580A AT364819B (de) 1976-08-05 1980-05-27 Verfahren zur stereospezifischen synthese von optisch aktiven, n-substituierten pyrrolidinen
SE8009074A SE8009074L (sv) 1976-08-05 1980-12-22 Forfarande for framstellning av n-substituerade pyrrolidiner
CH4181A CH626341A5 (en) 1976-08-05 1981-01-06 Process for the stereospecific synthesis of N-substituted pyrrolidines and their use
NO812871A NO812871L (no) 1976-08-05 1981-08-25 Fremgangsmaate for fremstilling av n-substituerte n-pyrrolidiner

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7635476A FR2372157A1 (fr) 1976-11-25 1976-11-25 Procede de synthese stereospecifique de n-alkyl- pyrrolidines optiquement actives

Publications (2)

Publication Number Publication Date
FR2372157A1 true FR2372157A1 (fr) 1978-06-23
FR2372157B1 FR2372157B1 (OSRAM) 1979-03-30

Family

ID=9180287

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7635476A Granted FR2372157A1 (fr) 1976-08-05 1976-11-25 Procede de synthese stereospecifique de n-alkyl- pyrrolidines optiquement actives

Country Status (1)

Country Link
FR (1) FR2372157A1 (OSRAM)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Also Published As

Publication number Publication date
FR2372157B1 (OSRAM) 1979-03-30

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