ES2158896T3 - Nuevo compuesto intermedio para uso en sintesis y procedimiento para producir un derivado de aminopiperazina. - Google Patents

Nuevo compuesto intermedio para uso en sintesis y procedimiento para producir un derivado de aminopiperazina.

Info

Publication number
ES2158896T3
ES2158896T3 ES94917789T ES94917789T ES2158896T3 ES 2158896 T3 ES2158896 T3 ES 2158896T3 ES 94917789 T ES94917789 T ES 94917789T ES 94917789 T ES94917789 T ES 94917789T ES 2158896 T3 ES2158896 T3 ES 2158896T3
Authority
ES
Spain
Prior art keywords
aryl
synthesis
procedure
produce
intermediate compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94917789T
Other languages
English (en)
Inventor
Teruo Oku
Hiroshi Kayakiri
Hirokazu Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2158896T3 publication Critical patent/ES2158896T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28Nitrogen atoms
    • C07D295/32Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

UN PROCESO INDUSTRIAL NOVEDOSO PARA PRODUCIR UN COMPUESTO REPRESENTADO POR LA FORMULA GENERAL (I), O UNA SAL DE LA MISMA, EXCELENTE EN PUREZA Y PRODUCCION, QUE INCLUYE REACCIONAR UN COMPUESTO REPRESENTADO POR LA FORMULA GENRAL (II) O UNA SAL DEL MISMO CON UN COMPUESTO REPRESENTADO POR R{SUP,3}-A-OH, UN DERIVADO REACTIVO DEL MISMO O SAL. EN DIHCAS FORMULAS, R{SUP,2} REPRESENTA CICLO(BAJO)ALQUIL, ARIL O ARIL(BAJO)ALQUIL, CADA UNO DE LOS CUALES PUEDE SER HALOGENADO; R{SUP,3} REPRESENTA ALQUIL BAJO, ARIL, ARIL(BAJO)ALCOXI O HETEROCICLO, PUDIENDO ESTAR CADA UNO HALOGENADO; A REPRESENTA - C(=0)-, -SO{SUB,2}- O ALQUILENO BAJO; E Y REPRESENTA -C(=0)-, -SO{SUB,2}- O -C(=0)-NH-.
ES94917789T 1993-06-18 1994-06-08 Nuevo compuesto intermedio para uso en sintesis y procedimiento para producir un derivado de aminopiperazina. Expired - Lifetime ES2158896T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17242793 1993-06-18

Publications (1)

Publication Number Publication Date
ES2158896T3 true ES2158896T3 (es) 2001-09-16

Family

ID=15941775

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94917789T Expired - Lifetime ES2158896T3 (es) 1993-06-18 1994-06-08 Nuevo compuesto intermedio para uso en sintesis y procedimiento para producir un derivado de aminopiperazina.

Country Status (14)

Country Link
US (1) US5708172A (es)
EP (1) EP0704439B1 (es)
JP (1) JP3489116B2 (es)
KR (1) KR100324040B1 (es)
CN (1) CN1046716C (es)
AT (1) ATE204264T1 (es)
CA (1) CA2165326A1 (es)
DE (1) DE69427978T2 (es)
DK (1) DK0704439T3 (es)
ES (1) ES2158896T3 (es)
GR (1) GR3036405T3 (es)
PT (1) PT704439E (es)
TW (1) TW246672B (es)
WO (1) WO1995000502A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995033251A1 (en) * 1994-05-31 1995-12-07 Re-Mark-It (Holdings) Limited Rewritable erasable labels
KR20010030637A (ko) * 1997-10-09 2001-04-16 후지야마 아키라 아미노피페라진 유도체의 신규한 제조방법
AUPP818099A0 (en) * 1999-01-14 1999-02-11 Fujisawa Pharmaceutical Co., Ltd. New n-containing heterocyclic compounds
US6344358B1 (en) 1999-05-28 2002-02-05 Fujisawa Pharmaceutical Co., Ltd. Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property
JPWO2002045715A1 (ja) * 2000-12-07 2004-04-08 藤沢薬品工業株式会社 抗痴呆効果増強剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS3919175B1 (es) * 1963-08-23 1964-09-07
US3200121A (en) * 1964-08-05 1965-08-10 Searle & Co Disubstituted-alkanoyl hydrazides of 1-aminopiperazines
US3200120A (en) * 1964-08-05 1965-08-10 Searle & Co Hydrazides of 4-substituted 1-aminopiperazines
ZA786426B (en) * 1977-11-25 1979-10-31 Scras New indulo(2,3-a)quinolizidines,preparation and therapeutic use
IT1222867B (it) * 1987-10-12 1990-09-12 Zambon Spa Ftalazino derivati ad attivita' farmaceutica
GB8917687D0 (en) * 1989-08-02 1989-09-20 Fujisawa Pharmaceutical Co Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
US5250528A (en) * 1989-08-02 1993-10-05 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives

Also Published As

Publication number Publication date
CN1128027A (zh) 1996-07-31
DE69427978T2 (de) 2001-11-29
CN1046716C (zh) 1999-11-24
TW246672B (es) 1995-05-01
US5708172A (en) 1998-01-13
ATE204264T1 (de) 2001-09-15
EP0704439A1 (en) 1996-04-03
DE69427978D1 (de) 2001-09-20
KR100324040B1 (ko) 2002-07-22
DK0704439T3 (da) 2001-10-08
EP0704439B1 (en) 2001-08-16
EP0704439A4 (en) 1996-02-19
PT704439E (pt) 2001-12-28
KR960703119A (ko) 1996-06-19
GR3036405T3 (en) 2001-11-30
JP3489116B2 (ja) 2004-01-19
CA2165326A1 (en) 1995-01-05
WO1995000502A1 (fr) 1995-01-05

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