HUT51614A - Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents - Google Patents

Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents

Info

Publication number
HUT51614A
HUT51614A HU885132A HU513288A HUT51614A HU T51614 A HUT51614 A HU T51614A HU 885132 A HU885132 A HU 885132A HU 513288 A HU513288 A HU 513288A HU T51614 A HUT51614 A HU T51614A
Authority
HU
Hungary
Prior art keywords
producing
lower alkyl
nitriferous
cardio
illnesses
Prior art date
Application number
HU885132A
Other languages
Hungarian (hu)
Inventor
Takao Takaya
Hisashi Takasugi
Kimio Esumi
Atsushi Kuno
Hiroyoshi Sakai
Kazuhiro Maeda
Yoshie Sakamoto
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858530602A external-priority patent/GB8530602D0/en
Priority to GB858530602A priority Critical patent/GB8530602D0/en
Priority to ES198686309657T priority patent/ES2037665T3/en
Priority to DE8686309657T priority patent/DE3676179D1/en
Priority to AT86309657T priority patent/ATE59033T1/en
Priority to EP86309657A priority patent/EP0228845B1/en
Priority to JP61297227A priority patent/JPH0739391B2/en
Priority to US06/940,923 priority patent/US4831030A/en
Priority to US07/184,195 priority patent/US4857527A/en
Priority claimed from US07/184,195 external-priority patent/US4857527A/en
Priority to JP63144192A priority patent/JPS6479155A/en
Priority to ZA886889A priority patent/ZA886889B/en
Priority claimed from ZA886889A external-priority patent/ZA886889B/en
Priority to FI884418A priority patent/FI884418A/en
Priority to DE88309155T priority patent/DE3882476T2/en
Priority to JP63249593A priority patent/JPH01207234A/en
Priority claimed from EP88309155A external-priority patent/EP0311322B1/en
Priority to ES88309155T priority patent/ES2058301T3/en
Priority to EP88309155A priority patent/EP0311322B1/en
Priority to AT88309155T priority patent/ATE91626T1/en
Priority to AU23338/88A priority patent/AU621067B2/en
Priority to KR1019880012908A priority patent/KR890006239A/en
Priority to CN88109132A priority patent/CN1041589A/en
Priority to NO88884399A priority patent/NO884399L/en
Priority to HU885132A priority patent/HUT51614A/en
Priority to DK554988A priority patent/DK554988A/en
Priority to CA000579295A priority patent/CA1317296C/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Priority to US07/286,169 priority patent/US4931453A/en
Priority to US07/294,743 priority patent/US4990507A/en
Publication of HUT51614A publication Critical patent/HUT51614A/en
Priority to GR90401044T priority patent/GR3001506T3/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pharmaceutical compsn. contains a phenyl-substd. pyridine or pyridazine cpd. of formula (I), or its salt, together with a standard carrier or excipient. - R1 = lower alkyl substd. by heterocyclyl, carbamoyl substd. by heterocyclyl-lower alkyl or lower alkylamino-lower alkyl; N-contg. heterocyclic carbonyl (opt. substd. by lower alkyl) or ureido substd. by lower alkylamino-lower alkyl; (a) R2 = nitrophenyl; X is N or CR3; or (b) R2 = lower alkyl; X is CR'3; R3 = lower alkyl; R'3 = nitrophenyl. - More specifically, R1 = morpholino-alkyl carbamoyl; R2 = nitrophenyl; X = CR3; most pref. is 3-(2-morpholinoethylcarbamoyl)-2 methyl-4- (3-nitrophenyl)-6- phenylpyridine (Ia) and its di-hydrochloride.
HU885132A 1985-12-12 1988-10-04 Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents HUT51614A (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
GB858530602A GB8530602D0 (en) 1985-12-12 1985-12-12 Heterocyclic compounds
ES198686309657T ES2037665T3 (en) 1985-12-12 1986-12-11 PROCEDURE FOR THE PREPARATION OF HETERO-CYCLE COMPOUNDS CONTAINING N.
DE8686309657T DE3676179D1 (en) 1985-12-12 1986-12-11 N-CONTAINING HETEROCYCLIC COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME.
AT86309657T ATE59033T1 (en) 1985-12-12 1986-12-11 N-CONTAINING HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM.
EP86309657A EP0228845B1 (en) 1985-12-12 1986-12-11 N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same
JP61297227A JPH0739391B2 (en) 1985-12-12 1986-12-12 N-containing heterocyclic compound
US06/940,923 US4831030A (en) 1985-12-12 1986-12-12 Diphenylpyridine compounds, processes for the preparation thereof and composition comprising the same
US07/184,195 US4857527A (en) 1985-12-12 1988-04-21 Morpholine containing pyridine compounds, compositions and use
JP63144192A JPS6479155A (en) 1987-06-11 1988-06-10 Diphenylpyridine compound
ZA886889A ZA886889B (en) 1987-10-05 1988-09-15 A cardioprotective agent and a therapeutic agent for ischemic disease comprising n-containing heterocyclic compounds,and a process for the preparation of the same compounds
FI884418A FI884418A (en) 1987-10-05 1988-09-27 HJAERTSKYDDANDE AEMNE OCH ETT THERAPEUTIC AEMNE FOER ISCHEMISKA SJUKDOMAR OMFATTANDE N-INNEHAOLLANDE HETEROCYCLISKA FOERENINGAR, OCH ETT FOERFARANDE FOER FRAMSTAELLNING AV DESSA FOERENAR.
EP88309155A EP0311322B1 (en) 1987-10-05 1988-10-03 Pyridine or pyridazine derivatives as cardio-protective agents and for the treatment of ischemic disease, and process for their preparation
AT88309155T ATE91626T1 (en) 1987-10-05 1988-10-03 PYRIDINE OR PYRIDAZINE DERIVATIVES AS CARDIOPROTECTIVES AND FOR THE TREATMENT OF ISCHAEMIC DISEASES AND MANUFACTURING PROCESS.
AU23338/88A AU621067B2 (en) 1987-10-05 1988-10-03 A cardioprotective agent and a therapeutic agent for ischemic disease comprising N-containing heterocyclic compounds, and a process for the preparation of the same compounds
JP63249593A JPH01207234A (en) 1987-10-05 1988-10-03 Therapeutic agent for ischemic diseases and cardiac muscle-protecting agent
DE88309155T DE3882476T2 (en) 1987-10-05 1988-10-03 Pyridine or pyridazine derivatives as cardioprotectants and for the treatment of ischemic complaints and manufacturing process.
ES88309155T ES2058301T3 (en) 1987-10-05 1988-10-03 DERIVATIVES OF PIRIDINE OR PIRIDAZINE AS CARDIOPROTECTING AGENTS AND FOR THE TREATMENT OF ISCHEMIC DISEASES, AND PROCEDURE FOR THEIR PREPARATION.
CA000579295A CA1317296C (en) 1987-10-05 1988-10-04 Cardioprotective agent and a therapeutic agent for ischemic disease comprising n-containing heterocyclic compounds, and a process for the preparation of the same compounds
DK554988A DK554988A (en) 1987-10-05 1988-10-04 HEART PROTECTIVE AGENT
HU885132A HUT51614A (en) 1985-12-12 1988-10-04 Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents
NO88884399A NO884399L (en) 1987-10-05 1988-10-04 HEART PROTECTIVE AGENT.
CN88109132A CN1041589A (en) 1987-10-05 1988-10-04 The preparation method who contains cardioprotective agent and the ischemic disease therapeutical agent and the compound of N-heterogeneous ring compound
KR1019880012908A KR890006239A (en) 1987-10-05 1988-10-04 Cardiac protective agents and N-containing heterocyclic compounds containing N-containing heterocyclic compounds and methods for preparing N-containing heterocyclic compounds
US07/286,169 US4931453A (en) 1985-12-12 1988-12-19 Di phenylpyridazine compounds, processes for the preparation thereof and pharmaceutical compositions comprising the same
US07/294,743 US4990507A (en) 1985-12-12 1989-01-09 N-containing heterocyclic compounds, and composition comprising the same
GR90401044T GR3001506T3 (en) 1985-12-12 1991-02-26 N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB858530602A GB8530602D0 (en) 1985-12-12 1985-12-12 Heterocyclic compounds
JP14599687 1987-06-11
JP25177187 1987-10-05
US07/184,195 US4857527A (en) 1985-12-12 1988-04-21 Morpholine containing pyridine compounds, compositions and use
ZA886889A ZA886889B (en) 1987-10-05 1988-09-15 A cardioprotective agent and a therapeutic agent for ischemic disease comprising n-containing heterocyclic compounds,and a process for the preparation of the same compounds
EP88309155A EP0311322B1 (en) 1987-10-05 1988-10-03 Pyridine or pyridazine derivatives as cardio-protective agents and for the treatment of ischemic disease, and process for their preparation
HU885132A HUT51614A (en) 1985-12-12 1988-10-04 Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents

Publications (1)

Publication Number Publication Date
HUT51614A true HUT51614A (en) 1990-05-28

Family

ID=27561974

Family Applications (1)

Application Number Title Priority Date Filing Date
HU885132A HUT51614A (en) 1985-12-12 1988-10-04 Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents

Country Status (1)

Country Link
HU (1) HUT51614A (en)

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