HUT51614A - Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents - Google Patents
Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agentsInfo
- Publication number
- HUT51614A HUT51614A HU885132A HU513288A HUT51614A HU T51614 A HUT51614 A HU T51614A HU 885132 A HU885132 A HU 885132A HU 513288 A HU513288 A HU 513288A HU T51614 A HUT51614 A HU T51614A
- Authority
- HU
- Hungary
- Prior art keywords
- producing
- lower alkyl
- nitriferous
- cardio
- illnesses
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Pharmaceutical compsn. contains a phenyl-substd. pyridine or pyridazine cpd. of formula (I), or its salt, together with a standard carrier or excipient. - R1 = lower alkyl substd. by heterocyclyl, carbamoyl substd. by heterocyclyl-lower alkyl or lower alkylamino-lower alkyl; N-contg. heterocyclic carbonyl (opt. substd. by lower alkyl) or ureido substd. by lower alkylamino-lower alkyl; (a) R2 = nitrophenyl; X is N or CR3; or (b) R2 = lower alkyl; X is CR'3; R3 = lower alkyl; R'3 = nitrophenyl. - More specifically, R1 = morpholino-alkyl carbamoyl; R2 = nitrophenyl; X = CR3; most pref. is 3-(2-morpholinoethylcarbamoyl)-2 methyl-4- (3-nitrophenyl)-6- phenylpyridine (Ia) and its di-hydrochloride.
Priority Applications (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858530602A GB8530602D0 (en) | 1985-12-12 | 1985-12-12 | Heterocyclic compounds |
ES198686309657T ES2037665T3 (en) | 1985-12-12 | 1986-12-11 | PROCEDURE FOR THE PREPARATION OF HETERO-CYCLE COMPOUNDS CONTAINING N. |
DE8686309657T DE3676179D1 (en) | 1985-12-12 | 1986-12-11 | N-CONTAINING HETEROCYCLIC COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME. |
AT86309657T ATE59033T1 (en) | 1985-12-12 | 1986-12-11 | N-CONTAINING HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM. |
EP86309657A EP0228845B1 (en) | 1985-12-12 | 1986-12-11 | N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same |
JP61297227A JPH0739391B2 (en) | 1985-12-12 | 1986-12-12 | N-containing heterocyclic compound |
US06/940,923 US4831030A (en) | 1985-12-12 | 1986-12-12 | Diphenylpyridine compounds, processes for the preparation thereof and composition comprising the same |
US07/184,195 US4857527A (en) | 1985-12-12 | 1988-04-21 | Morpholine containing pyridine compounds, compositions and use |
JP63144192A JPS6479155A (en) | 1987-06-11 | 1988-06-10 | Diphenylpyridine compound |
ZA886889A ZA886889B (en) | 1987-10-05 | 1988-09-15 | A cardioprotective agent and a therapeutic agent for ischemic disease comprising n-containing heterocyclic compounds,and a process for the preparation of the same compounds |
FI884418A FI884418A (en) | 1987-10-05 | 1988-09-27 | HJAERTSKYDDANDE AEMNE OCH ETT THERAPEUTIC AEMNE FOER ISCHEMISKA SJUKDOMAR OMFATTANDE N-INNEHAOLLANDE HETEROCYCLISKA FOERENINGAR, OCH ETT FOERFARANDE FOER FRAMSTAELLNING AV DESSA FOERENAR. |
EP88309155A EP0311322B1 (en) | 1987-10-05 | 1988-10-03 | Pyridine or pyridazine derivatives as cardio-protective agents and for the treatment of ischemic disease, and process for their preparation |
AT88309155T ATE91626T1 (en) | 1987-10-05 | 1988-10-03 | PYRIDINE OR PYRIDAZINE DERIVATIVES AS CARDIOPROTECTIVES AND FOR THE TREATMENT OF ISCHAEMIC DISEASES AND MANUFACTURING PROCESS. |
AU23338/88A AU621067B2 (en) | 1987-10-05 | 1988-10-03 | A cardioprotective agent and a therapeutic agent for ischemic disease comprising N-containing heterocyclic compounds, and a process for the preparation of the same compounds |
JP63249593A JPH01207234A (en) | 1987-10-05 | 1988-10-03 | Therapeutic agent for ischemic diseases and cardiac muscle-protecting agent |
DE88309155T DE3882476T2 (en) | 1987-10-05 | 1988-10-03 | Pyridine or pyridazine derivatives as cardioprotectants and for the treatment of ischemic complaints and manufacturing process. |
ES88309155T ES2058301T3 (en) | 1987-10-05 | 1988-10-03 | DERIVATIVES OF PIRIDINE OR PIRIDAZINE AS CARDIOPROTECTING AGENTS AND FOR THE TREATMENT OF ISCHEMIC DISEASES, AND PROCEDURE FOR THEIR PREPARATION. |
CA000579295A CA1317296C (en) | 1987-10-05 | 1988-10-04 | Cardioprotective agent and a therapeutic agent for ischemic disease comprising n-containing heterocyclic compounds, and a process for the preparation of the same compounds |
DK554988A DK554988A (en) | 1987-10-05 | 1988-10-04 | HEART PROTECTIVE AGENT |
HU885132A HUT51614A (en) | 1985-12-12 | 1988-10-04 | Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents |
NO88884399A NO884399L (en) | 1987-10-05 | 1988-10-04 | HEART PROTECTIVE AGENT. |
CN88109132A CN1041589A (en) | 1987-10-05 | 1988-10-04 | The preparation method who contains cardioprotective agent and the ischemic disease therapeutical agent and the compound of N-heterogeneous ring compound |
KR1019880012908A KR890006239A (en) | 1987-10-05 | 1988-10-04 | Cardiac protective agents and N-containing heterocyclic compounds containing N-containing heterocyclic compounds and methods for preparing N-containing heterocyclic compounds |
US07/286,169 US4931453A (en) | 1985-12-12 | 1988-12-19 | Di phenylpyridazine compounds, processes for the preparation thereof and pharmaceutical compositions comprising the same |
US07/294,743 US4990507A (en) | 1985-12-12 | 1989-01-09 | N-containing heterocyclic compounds, and composition comprising the same |
GR90401044T GR3001506T3 (en) | 1985-12-12 | 1991-02-26 | N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same |
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858530602A GB8530602D0 (en) | 1985-12-12 | 1985-12-12 | Heterocyclic compounds |
JP14599687 | 1987-06-11 | ||
JP25177187 | 1987-10-05 | ||
US07/184,195 US4857527A (en) | 1985-12-12 | 1988-04-21 | Morpholine containing pyridine compounds, compositions and use |
ZA886889A ZA886889B (en) | 1987-10-05 | 1988-09-15 | A cardioprotective agent and a therapeutic agent for ischemic disease comprising n-containing heterocyclic compounds,and a process for the preparation of the same compounds |
EP88309155A EP0311322B1 (en) | 1987-10-05 | 1988-10-03 | Pyridine or pyridazine derivatives as cardio-protective agents and for the treatment of ischemic disease, and process for their preparation |
HU885132A HUT51614A (en) | 1985-12-12 | 1988-10-04 | Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents |
Publications (1)
Publication Number | Publication Date |
---|---|
HUT51614A true HUT51614A (en) | 1990-05-28 |
Family
ID=27561974
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU885132A HUT51614A (en) | 1985-12-12 | 1988-10-04 | Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents |
Country Status (1)
Country | Link |
---|---|
HU (1) | HUT51614A (en) |
-
1988
- 1988-10-04 HU HU885132A patent/HUT51614A/en unknown
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