FR2354340A1 - Procede pour la recuperation de l'antithrombine iii - Google Patents
Procede pour la recuperation de l'antithrombine iiiInfo
- Publication number
- FR2354340A1 FR2354340A1 FR7717655A FR7717655A FR2354340A1 FR 2354340 A1 FR2354340 A1 FR 2354340A1 FR 7717655 A FR7717655 A FR 7717655A FR 7717655 A FR7717655 A FR 7717655A FR 2354340 A1 FR2354340 A1 FR 2354340A1
- Authority
- FR
- France
- Prior art keywords
- antithrombin iii
- albumin
- factor viii
- recovering
- gamma globulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004411 Antithrombin III Human genes 0.000 title abstract 2
- 108090000935 Antithrombin III Proteins 0.000 title abstract 2
- 229960005348 antithrombin iii Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 108010088751 Albumins Proteins 0.000 abstract 2
- 102000009027 Albumins Human genes 0.000 abstract 2
- 108010054218 Factor VIII Proteins 0.000 abstract 2
- 102000001690 Factor VIII Human genes 0.000 abstract 2
- 108010049003 Fibrinogen Proteins 0.000 abstract 2
- 102000008946 Fibrinogen Human genes 0.000 abstract 2
- 108010094028 Prothrombin Proteins 0.000 abstract 2
- 102100027378 Prothrombin Human genes 0.000 abstract 2
- 229960000301 factor viii Drugs 0.000 abstract 2
- 108010074605 gamma-Globulins Proteins 0.000 abstract 2
- 229940039716 prothrombin Drugs 0.000 abstract 2
- FBPFZTCFMRRESA-ZXXMMSQZSA-N D-iditol Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-ZXXMMSQZSA-N 0.000 abstract 1
- 239000002156 adsorbate Substances 0.000 abstract 1
- 239000004019 antithrombin Substances 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 229940012952 fibrinogen Drugs 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
- 229940078499 tricalcium phosphate Drugs 0.000 abstract 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 abstract 1
- 235000019731 tricalcium phosphate Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8128—Antithrombin III
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
- Y10S530/831—Cohn fractions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/694,167 US4087415A (en) | 1976-06-09 | 1976-06-09 | Antithrombin III |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2354340A1 true FR2354340A1 (fr) | 1978-01-06 |
| FR2354340B1 FR2354340B1 (enExample) | 1982-09-10 |
Family
ID=24787683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7717655A Granted FR2354340A1 (fr) | 1976-06-09 | 1977-06-09 | Procede pour la recuperation de l'antithrombine iii |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4087415A (enExample) |
| JP (1) | JPS52151710A (enExample) |
| DE (1) | DE2725711A1 (enExample) |
| FR (1) | FR2354340A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1980002426A1 (fr) * | 1979-05-04 | 1980-11-13 | Merieux Inst | Concentres de complexe prothrombinique, preparation et application |
| FR2460138A1 (fr) * | 1978-01-07 | 1981-01-23 | Green Cross Corp | Preparation antithrombinique et son procede de fabrication |
| EP0090505A3 (en) * | 1982-03-03 | 1984-02-22 | Genentech, Inc. | Human antithrombin iii, dna sequences therefor, expression vehicles and cloning vectors containing such sequences and cell cultures transformed thereby, a process for expressing human antithrombin iii, and pharmaceutical compositions comprising it |
| US4517294A (en) * | 1982-03-03 | 1985-05-14 | Genentech, Inc. | Human antithrombin III |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1603244A (en) * | 1977-05-20 | 1981-11-18 | Max Planck Gesellschaft | Medicaments for the suppression of pathological processes |
| US4170639A (en) * | 1978-07-10 | 1979-10-09 | Warner-Lambert Company | Antihemophilic factor concentrate and its production |
| DE2902158A1 (de) * | 1979-01-20 | 1980-07-31 | Biotest Serum Institut Gmbh | Verfahren zur herstellung von fibrinogen, einem die gerinnungsfaktoren ii, vii, ix und x enthaltenden prothrombinkomplex, antithrombin iii und einer loesung von lagerstabilen serumproteinen |
| SE448945B (sv) * | 1979-12-20 | 1987-03-30 | Blombaeck E G B | Forfarande for rening och /eller koncentrering av faktor viii-komplexet |
| JPS5699422A (en) * | 1980-01-10 | 1981-08-10 | Toyo Soda Mfg Co Ltd | Separation of plasma albumin |
| US4287180A (en) * | 1980-01-28 | 1981-09-01 | Baxter Travenol Laboratories, Inc. | Method for treating blood clotting factor inhibitors |
| US4446314A (en) * | 1980-09-30 | 1984-05-01 | Cutter Laboratories, Inc. | Fractionation of heparin |
| US4386025A (en) * | 1980-09-30 | 1983-05-31 | Cutter Laboratories, Inc. | Method of preparing antithrombin |
| DE3038163A1 (de) * | 1980-10-09 | 1982-05-06 | Boehringer Mannheim Gmbh, 6800 Mannheim | Thrombininhibitor, seine herstellung und verwendung |
| US4632981A (en) * | 1982-07-30 | 1986-12-30 | Genentech, Inc. | Human antithrombin III |
| AT379310B (de) * | 1983-05-20 | 1985-12-27 | Immuno Ag | Verfahren zur herstellung eines antithrombin iii-heparin- bzw. antithrombin iii-heparinoidkonzentrates |
| AU578554B2 (en) * | 1986-01-24 | 1988-10-27 | Japanese Red Cross Society | Centrifugal method of separating blood components |
| EP1117428B1 (en) | 1998-10-08 | 2003-09-24 | Children's Hospital | Compositions and their use for inhibiting angiogenesis |
| SE0203770D0 (sv) * | 2002-12-19 | 2002-12-19 | Biovitrum Ab | Method of separation |
| PT2503995T (pt) * | 2009-11-24 | 2017-11-23 | Grifols Therapeutics Inc | Métodos de liofilização, composições e kits |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2154483A1 (enExample) * | 1971-09-08 | 1973-05-11 | Kabi Ab |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3631018A (en) * | 1970-05-01 | 1971-12-28 | Baxter Laboratories Inc | Production of stable high-potency human ahf using polyethylene glycol and glycine to fractionate a cryoprecipitate of ahf concentrate |
| US3682881A (en) * | 1970-10-02 | 1972-08-08 | Baxter Laboratories Inc | Fractionation of plasma using glycine and polyethylene glycol |
| US3770631A (en) * | 1971-06-29 | 1973-11-06 | Baxter Laboratories Inc | Clarification of blood serum and plasma |
| US3839314A (en) * | 1971-06-29 | 1974-10-01 | Baxter Laboratories Inc | Clarification of blood serum and plasma using block copolymers of ethylene oxide and polyoxypropylene |
| US3956259A (en) * | 1973-01-30 | 1976-05-11 | Baxter Laboratories, Inc. | Fractionation of blood using block copolymer of ethylene oxide and polyoxypropylene polymer to recover fraction suitable for organ perfusate |
| US3880989A (en) * | 1973-01-30 | 1975-04-29 | Baxter Laboratories Inc | Production of antisera comprising fractionating plasma or serum with an ethylene oxide-polyoxypropylene block copolymer |
| US3850903A (en) * | 1973-06-21 | 1974-11-26 | S Mankarious | Plasma volume expander prepared from cohn iv precipitate using block copolymers of ethylene oxide and polyoxypropylene |
-
1976
- 1976-06-09 US US05/694,167 patent/US4087415A/en not_active Expired - Lifetime
-
1977
- 1977-06-06 JP JP6721977A patent/JPS52151710A/ja active Pending
- 1977-06-07 DE DE19772725711 patent/DE2725711A1/de not_active Withdrawn
- 1977-06-09 FR FR7717655A patent/FR2354340A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2154483A1 (enExample) * | 1971-09-08 | 1973-05-11 | Kabi Ab |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2460138A1 (fr) * | 1978-01-07 | 1981-01-23 | Green Cross Corp | Preparation antithrombinique et son procede de fabrication |
| WO1980002426A1 (fr) * | 1979-05-04 | 1980-11-13 | Merieux Inst | Concentres de complexe prothrombinique, preparation et application |
| FR2472390A1 (fr) * | 1979-05-04 | 1981-07-03 | Merieux Inst | Procede de preparation de concentres de complexe prothrombinique hautement purifies, et concentres obtenus |
| EP0090505A3 (en) * | 1982-03-03 | 1984-02-22 | Genentech, Inc. | Human antithrombin iii, dna sequences therefor, expression vehicles and cloning vectors containing such sequences and cell cultures transformed thereby, a process for expressing human antithrombin iii, and pharmaceutical compositions comprising it |
| US4517294A (en) * | 1982-03-03 | 1985-05-14 | Genentech, Inc. | Human antithrombin III |
Also Published As
| Publication number | Publication date |
|---|---|
| US4087415A (en) | 1978-05-02 |
| JPS52151710A (en) | 1977-12-16 |
| DE2725711A1 (de) | 1977-12-22 |
| FR2354340B1 (enExample) | 1982-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CA | Change of address | ||
| TP | Transmission of property | ||
| ST | Notification of lapse |