FR2336923A1 - Agent anti-inflammatoire a base d'un derive benzoyle - Google Patents

Agent anti-inflammatoire a base d'un derive benzoyle

Info

Publication number
FR2336923A1
FR2336923A1 FR7638882A FR7638882A FR2336923A1 FR 2336923 A1 FR2336923 A1 FR 2336923A1 FR 7638882 A FR7638882 A FR 7638882A FR 7638882 A FR7638882 A FR 7638882A FR 2336923 A1 FR2336923 A1 FR 2336923A1
Authority
FR
France
Prior art keywords
inflammatory agent
agent based
benzoyl derivative
benzoyl
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7638882A
Other languages
English (en)
French (fr)
Other versions
FR2336923B1 (Direct
Inventor
Yasuhiko Hamazaki
Shozo Kawabata
Toshiyuki Yamamoto
Yasuo Shiraishi
Akira Ueno
Koji Amemiya
Katzumasa Saga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Chemical Co Ltd filed Critical Kaken Chemical Co Ltd
Publication of FR2336923A1 publication Critical patent/FR2336923A1/fr
Application granted granted Critical
Publication of FR2336923B1 publication Critical patent/FR2336923B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/784—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic with all keto groups bound to a non-condensed ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/792—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
    • C07C49/796—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7638882A 1976-01-01 1976-12-23 Agent anti-inflammatoire a base d'un derive benzoyle Granted FR2336923A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51000232A JPS5946205B2 (ja) 1976-01-01 1976-01-01 ベンゾイル誘導体を有効成分とする消炎鎮痛剤

Publications (2)

Publication Number Publication Date
FR2336923A1 true FR2336923A1 (fr) 1977-07-29
FR2336923B1 FR2336923B1 (Direct) 1980-04-11

Family

ID=11468211

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7638882A Granted FR2336923A1 (fr) 1976-01-01 1976-12-23 Agent anti-inflammatoire a base d'un derive benzoyle

Country Status (8)

Country Link
US (1) US4124726A (Direct)
JP (1) JPS5946205B2 (Direct)
AU (1) AU504411B2 (Direct)
BE (1) BE850024A (Direct)
DE (1) DE2659580A1 (Direct)
FR (1) FR2336923A1 (Direct)
GB (1) GB1556263A (Direct)
NL (1) NL7614567A (Direct)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023357A1 (en) * 1992-05-21 1993-11-25 Research Corporation Technologies, Inc. Stilbene derivatives as anticancer agents

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237140A (en) * 1979-05-18 1980-12-02 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and acetaminophen
US5236952A (en) * 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
DE3643403A1 (de) * 1986-12-19 1988-06-30 Shell Agrar Gmbh & Co Kg Benzophenone und verfahren zu ihrer herstellung
DE68915269T2 (de) * 1988-11-25 1994-09-29 Dainippon Ink & Chemicals Polyvalentes entzündungshemmendes mittel.
JP2664790B2 (ja) * 1990-01-10 1997-10-22 サンスター株式会社 紅斑抑制用の外用抗炎症剤
DE59310066D1 (de) * 1992-11-04 2000-08-03 Clariant Gmbh Verfahren zur Herstellung fluorierter Benzile
US5773663A (en) * 1996-05-01 1998-06-30 American Cyanamid Company Fungicidal methods, compounds and compositions containing benzophenones
US5679866A (en) * 1995-01-20 1997-10-21 American Cyanamid Company Fungicidal methods, compounds and compositions containing benzophenones
US5723676A (en) * 1996-07-01 1998-03-03 Alliedsignal Inc. Process for producing benzophenone compounds
US5990056A (en) * 1997-06-04 1999-11-23 Mobil Oil Corporation Compositions containing an organo-substituted benzophenone
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
JP2008539047A (ja) 2005-04-28 2008-11-13 プロテウス バイオメディカル インコーポレイテッド ファーマインフォーマティックスシステム
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN102775289B (zh) * 2011-05-13 2015-04-22 山东中医药大学 白首乌二苯酮类化合物及其制备方法与用途
CN111393277B (zh) * 2020-03-15 2023-01-03 山西医科大学 4-丁基多羟基二苯甲酮类化合物衍生物及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2671016A (en) * 1951-10-23 1954-03-02 Monsanto Chemicals Herbicidal compositions
US2802032A (en) * 1955-06-22 1957-08-06 Monsanto Chemicals 3, 4-dimethylbenzophenone
US3924002A (en) * 1969-07-17 1975-12-02 Ciba Geigy Ag Method for combatting harmful microorganisms
US3755450A (en) * 1969-07-31 1973-08-28 American Cyanamid Co Free flowing uv absorber compositions with magnesium or zinc salts offatty acids
US3898275A (en) * 1970-11-20 1975-08-05 Sandoz Ag M-Substituted benzophenones
US3983176A (en) * 1971-08-24 1976-09-28 Nippon Kayaku Kabushiki Kaisha Benzophenones as plant growth regulants
DE2256662A1 (de) 1972-11-18 1974-05-22 Basf Ag Verfahren zur herstellung von 3-monochlor-2,4,5-trialkylbenzophenonen und 3,6-dichlor-2,4,5-trialkylbenzophenonen
US3954875A (en) * 1973-12-26 1976-05-04 Rohm And Haas Company Benzophenone herbicides
FR2292467A1 (fr) * 1974-11-28 1976-06-25 Roussel Uclaf Nouveaux derives de la benzophenone, leur procede de preparation et leur application comme medicament

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023357A1 (en) * 1992-05-21 1993-11-25 Research Corporation Technologies, Inc. Stilbene derivatives as anticancer agents

Also Published As

Publication number Publication date
NL7614567A (nl) 1977-07-05
GB1556263A (en) 1979-11-21
US4124726A (en) 1978-11-07
DE2659580A1 (de) 1977-07-14
JPS5946205B2 (ja) 1984-11-10
FR2336923B1 (Direct) 1980-04-11
AU504411B2 (en) 1979-10-11
JPS5283937A (en) 1977-07-13
BE850024A (fr) 1977-06-30
AU2071576A (en) 1978-06-22

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Legal Events

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