FR2277589A1 - Amino-alcools portant un substituant tricyclique, leurs sels non toxiques et procede pour leur preparation - Google Patents

Amino-alcools portant un substituant tricyclique, leurs sels non toxiques et procede pour leur preparation

Info

Publication number
FR2277589A1
FR2277589A1 FR7424202A FR7424202A FR2277589A1 FR 2277589 A1 FR2277589 A1 FR 2277589A1 FR 7424202 A FR7424202 A FR 7424202A FR 7424202 A FR7424202 A FR 7424202A FR 2277589 A1 FR2277589 A1 FR 2277589A1
Authority
FR
France
Prior art keywords
tricyclic
substitute
amino
preparation
toxic salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7424202A
Other languages
English (en)
Other versions
FR2277589B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE2335943A priority Critical patent/DE2335943C3/de
Priority to US05/484,353 priority patent/US3944566A/en
Priority to CA204,154A priority patent/CA1026325A/fr
Priority to ZA00744363A priority patent/ZA744363B/xx
Priority to FI2110/74A priority patent/FI59588C/fi
Priority to AT567174A priority patent/AT333756B/de
Priority to AU71032/74A priority patent/AU492690B2/en
Priority to GB3035674A priority patent/GB1410755A/en
Priority to CH953174A priority patent/CH602579A5/xx
Priority to AR254621A priority patent/AR202936A1/es
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to FR7424202A priority patent/FR2277589A1/fr
Priority to NLAANVRAGE7409439,A priority patent/NL184004C/xx
Priority to SE7409183A priority patent/SE410594B/xx
Priority to JP49081039A priority patent/JPS595577B2/ja
Publication of FR2277589A1 publication Critical patent/FR2277589A1/fr
Application granted granted Critical
Publication of FR2277589B1 publication Critical patent/FR2277589B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
    • C07D335/12—Thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
FR7424202A 1973-07-14 1974-07-11 Amino-alcools portant un substituant tricyclique, leurs sels non toxiques et procede pour leur preparation Granted FR2277589A1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DE2335943A DE2335943C3 (de) 1973-07-14 1973-07-14 Tricyclisch substituierte Aminoalkohole und ihre nichttoxischen Salze, Verfahren zu deren Herstellung und deren Verwendung bei der Bekämpfung von Herz- und Kreislauferkrankungen
US05/484,353 US3944566A (en) 1973-07-14 1974-06-28 Tricyclic substituted aminoalcohols
CA204,154A CA1026325A (fr) 1973-07-14 1974-07-05 Aminoalcools obtenus par substitution tricyclique
ZA00744363A ZA744363B (en) 1973-07-14 1974-07-08 New tricyclic substituted aminoalcohols and the preparation thereof
AT567174A AT333756B (de) 1973-07-14 1974-07-09 Verfahren zur herstellung von neuen tricyclisch substituierten aminoalkoholen und ihren nichttoxischen salzen
AU71032/74A AU492690B2 (en) 1973-07-14 1974-07-09 New tricyclic substituted aminoalcohols andthe preparation thereof
FI2110/74A FI59588C (fi) 1973-07-14 1974-07-09 Foerfarande foer framstaellning av hjaertverksamheten och blodcirkulationen paoverkande tricykliskt substituerade aminopropanoler och deras icke toxiska salter
GB3035674A GB1410755A (en) 1973-07-14 1974-07-09 Tricyclic substituted aminoalcohols and the preparation thereof
CH953174A CH602579A5 (fr) 1973-07-14 1974-07-10
AR254621A AR202936A1 (es) 1973-07-14 1974-07-10 Procedimiento para la obtencion de eteres de aminoalcoholes sustituidos derivados de dibenzooxepina, dibenzociclohepteno, tiaxanteno y xanteno y sus sales no toxicas
FR7424202A FR2277589A1 (fr) 1973-07-14 1974-07-11 Amino-alcools portant un substituant tricyclique, leurs sels non toxiques et procede pour leur preparation
NLAANVRAGE7409439,A NL184004C (nl) 1973-07-14 1974-07-12 Werkwijze voor het bereiden van tricyclisch gesubstitueerde aminoalkoholen en hun niet-toxische zouten, werkwijze voor het bereiden van een geneesmiddel met werking op hart en bloedsomloop, alsmede gevormd geneesmiddel.
SE7409183A SE410594B (sv) 1973-07-14 1974-07-12 Forfarande for framstellning av tricykliskt substituerade aminoalkoholer och deras icke toxiska salter
JP49081039A JPS595577B2 (ja) 1973-07-14 1974-07-15 チカンサレテイル サンカンシキアミノアルコ−ルノ セイホウ

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2335943A DE2335943C3 (de) 1973-07-14 1973-07-14 Tricyclisch substituierte Aminoalkohole und ihre nichttoxischen Salze, Verfahren zu deren Herstellung und deren Verwendung bei der Bekämpfung von Herz- und Kreislauferkrankungen
FR7424202A FR2277589A1 (fr) 1973-07-14 1974-07-11 Amino-alcools portant un substituant tricyclique, leurs sels non toxiques et procede pour leur preparation

Publications (2)

Publication Number Publication Date
FR2277589A1 true FR2277589A1 (fr) 1976-02-06
FR2277589B1 FR2277589B1 (fr) 1978-12-29

Family

ID=25765494

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7424202A Granted FR2277589A1 (fr) 1973-07-14 1974-07-11 Amino-alcools portant un substituant tricyclique, leurs sels non toxiques et procede pour leur preparation

Country Status (13)

Country Link
US (1) US3944566A (fr)
JP (1) JPS595577B2 (fr)
AR (1) AR202936A1 (fr)
AT (1) AT333756B (fr)
CA (1) CA1026325A (fr)
CH (1) CH602579A5 (fr)
DE (1) DE2335943C3 (fr)
FI (1) FI59588C (fr)
FR (1) FR2277589A1 (fr)
GB (1) GB1410755A (fr)
NL (1) NL184004C (fr)
SE (1) SE410594B (fr)
ZA (1) ZA744363B (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000805A1 (fr) * 1984-07-24 1986-02-13 Boehringer Mannheim Gmbh Produit pharmaceutique contenant du doxaminol pour influencer la rheologie du sang
WO1998056752A1 (fr) * 1997-06-11 1998-12-17 Nps Pharmaceuticals, Inc. Composes actifs sur un nouveau site des canaux calciques actives par les recepteurs servant au tratitement des troubles et des maladies neurologiques
US6211245B1 (en) 1993-02-08 2001-04-03 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US6750244B2 (en) 1993-02-08 2004-06-15 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US7087765B2 (en) 1995-06-07 2006-08-08 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1094576B (it) * 1978-05-09 1985-08-02 Pirelli Macchina per cordare cordicelle metalliche
JPS60154832A (ja) * 1984-01-23 1985-08-14 Sumitomo Electric Ind Ltd 異形素線の撚線装置
JPS6313879Y2 (fr) * 1984-09-04 1988-04-19
DE3689688T2 (de) * 1985-10-15 1994-08-25 Abbott Lab Verbindungen und Immunoassay für tricyclische Antidepressiva.
EP0347123A3 (fr) * 1988-06-17 1991-07-03 Fisons Corporation Dibenzo-cycloheptényl, -cycloheptyl et oxépinyl amines ayant des propriétés antihistaminiques
JPH02127581A (ja) * 1988-11-05 1990-05-16 Kanai Hiroyuki スチールコードの製造方法およびその装置
US5464840A (en) * 1993-12-06 1995-11-07 Schering Corporation Tricyclic derivatives, compositions and methods of use
US5574173A (en) * 1993-12-06 1996-11-12 Schering Corporation Tricyclic derivatives, compositions and methods of use
US5538986A (en) * 1993-12-06 1996-07-23 Schering Corporation Tricyclic derivatives, compositions and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3285919A (en) * 1961-05-10 1966-11-15 Sahyun Melville Piperazinyl alkyl thiaxanthene derivatives
NL138423C (fr) * 1966-07-14
NL130988C (fr) * 1966-07-21 Boehringer Mannheim Gmbh
US3872102A (en) * 1971-11-04 1975-03-18 En Nom Collectif Science Union Tricyclic compounds of aliphatic w-amino alcohols

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000805A1 (fr) * 1984-07-24 1986-02-13 Boehringer Mannheim Gmbh Produit pharmaceutique contenant du doxaminol pour influencer la rheologie du sang
US6211245B1 (en) 1993-02-08 2001-04-03 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US6750244B2 (en) 1993-02-08 2004-06-15 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US7268166B2 (en) 1993-02-08 2007-09-11 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US7087765B2 (en) 1995-06-07 2006-08-08 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
WO1998056752A1 (fr) * 1997-06-11 1998-12-17 Nps Pharmaceuticals, Inc. Composes actifs sur un nouveau site des canaux calciques actives par les recepteurs servant au tratitement des troubles et des maladies neurologiques

Also Published As

Publication number Publication date
SE7409183L (sv) 1975-01-15
NL184004C (nl) 1989-03-16
AR202936A1 (es) 1975-07-31
FR2277589B1 (fr) 1978-12-29
US3944566A (en) 1976-03-16
JPS595577B2 (ja) 1984-02-06
NL7409439A (nl) 1975-01-16
FI59588C (fi) 1981-09-10
NL184004B (nl) 1988-10-17
CH602579A5 (fr) 1978-07-31
DE2335943C3 (de) 1979-08-09
DE2335943B2 (de) 1978-12-07
CA1026325A (fr) 1978-02-14
SE410594B (sv) 1979-10-22
FI211074A (fr) 1975-01-15
FI59588B (fi) 1981-05-29
ZA744363B (en) 1975-08-27
ATA567174A (de) 1976-04-15
AT333756B (de) 1976-12-10
AU7103274A (en) 1976-01-15
JPS5037766A (fr) 1975-04-08
GB1410755A (en) 1975-10-22
DE2335943A1 (de) 1975-01-30

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