FR2273515A1 - Procede de fabrication d'un corps monolithique pour la liberation continue d'agents actifs, notamment de medicaments - Google Patents
Procede de fabrication d'un corps monolithique pour la liberation continue d'agents actifs, notamment de medicamentsInfo
- Publication number
- FR2273515A1 FR2273515A1 FR7517693A FR7517693A FR2273515A1 FR 2273515 A1 FR2273515 A1 FR 2273515A1 FR 7517693 A FR7517693 A FR 7517693A FR 7517693 A FR7517693 A FR 7517693A FR 2273515 A1 FR2273515 A1 FR 2273515A1
- Authority
- FR
- France
- Prior art keywords
- manufacturing
- active agents
- medicinal products
- continuous release
- monolithic body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US477297A US3923939A (en) | 1974-06-07 | 1974-06-07 | Process for improving release kinetics of a monolithic drug delivery device |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2273515A1 true FR2273515A1 (fr) | 1976-01-02 |
FR2273515B1 FR2273515B1 (fr) | 1980-02-15 |
Family
ID=23895337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7517693A Granted FR2273515A1 (fr) | 1974-06-07 | 1975-06-06 | Procede de fabrication d'un corps monolithique pour la liberation continue d'agents actifs, notamment de medicaments |
Country Status (10)
Country | Link |
---|---|
US (1) | US3923939A (fr) |
JP (1) | JPS6043327B2 (fr) |
CA (1) | CA1047403A (fr) |
CH (1) | CH611160A5 (fr) |
DE (1) | DE2525061C2 (fr) |
FR (1) | FR2273515A1 (fr) |
GB (1) | GB1477545A (fr) |
IT (1) | IT1036192B (fr) |
MX (1) | MX3007E (fr) |
SE (1) | SE405803B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0164311A2 (fr) * | 1984-05-10 | 1985-12-11 | Ciba-Geigy Ag | Dispositifs d'hydrogel contenant des substances actives dans lesquels le profil de concentration de la substance active contient un gradient de concentration sigmoidien pour une libération constante, leur fabrication et leur utilisation |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4177256A (en) * | 1973-04-25 | 1979-12-04 | Alza Corporation | Osmotic bursting drug delivery device |
US4145408A (en) * | 1976-08-16 | 1979-03-20 | The Procter & Gamble Company | Controlled release article |
HU174057B (hu) * | 1976-09-17 | 1979-10-28 | Richter Gedeon Vegyeszet | Sostav dlja pokrytij obespechivajuhhij uregulirovannuju otdachy aktivnogo vehhestva biologicheski aktivnykh preparatov i sposob poluchenija takikh preparatov s uregulirovannoj otdachej aktivnogo vehhestva |
US4190642A (en) * | 1978-04-17 | 1980-02-26 | Alza Corporation | Ocular therapeutic system for dispensing a medication formulation |
US4156604A (en) * | 1978-09-15 | 1979-05-29 | Minnesota Mining And Manufacturing Company | Controlled delivery of corrosion inhibitors for silver recovery cartridges |
US4333850A (en) * | 1979-06-15 | 1982-06-08 | Borg-Warner Corporation | Filled polymer composition for automatic addition of a corrosion inhibitor to a coolant system |
US4304765A (en) * | 1980-10-14 | 1981-12-08 | Alza Corporation | Ocular insert housing steroid in two different therapeutic forms |
US4432964A (en) * | 1981-08-24 | 1984-02-21 | Alza Corporation | Topical composition containing steroid in two forms released independently from polymeric carrier |
DE3218150C2 (de) * | 1982-05-14 | 1986-09-25 | Akzo Gmbh, 5600 Wuppertal | Wirkstoff enthaltender Körper für die Langzeitabgabe sowie Verfahren zu dessen Herstellung |
JPS5931701A (ja) * | 1982-08-16 | 1984-02-20 | Nitto Electric Ind Co Ltd | 液状活性物質含有膜及びその製造方法 |
US4557925A (en) * | 1982-07-08 | 1985-12-10 | Ab Ferrosan | Membrane-coated sustained-release tablets and method |
US4478818A (en) * | 1982-12-27 | 1984-10-23 | Alza Corporation | Ocular preparation housing steroid in two different therapeutic forms |
US4564364A (en) * | 1983-05-26 | 1986-01-14 | Alza Corporation | Active agent dispenser |
GB8331546D0 (en) * | 1983-11-25 | 1984-01-04 | Exxon Research Engineering Co | Polymeric compositions |
US4725439A (en) * | 1984-06-29 | 1988-02-16 | Alza Corporation | Transdermal drug delivery device |
US4704282A (en) * | 1984-06-29 | 1987-11-03 | Alza Corporation | Transdermal therapeutic system having improved delivery characteristics |
US4629619A (en) * | 1984-09-05 | 1986-12-16 | Ab Ferrosan | Membrane-coated sustained-release tablets and method |
US4629620A (en) * | 1984-09-05 | 1986-12-16 | Ab Ferrosan | Membrane-coated sustained-release tablets and method |
AU592546B2 (en) * | 1984-12-03 | 1990-01-18 | Baxter International Inc. | Drug delivery apparatus preventing local and systemic toxicity |
US4874366A (en) * | 1984-12-03 | 1989-10-17 | Baxter Internatiional Inc. | Housing enabling passive mixing of a beneficial agent with a diluent |
US4666704A (en) * | 1985-05-24 | 1987-05-19 | International Minerals & Chemical Corp. | Controlled release delivery system for macromolecules |
US4898733A (en) * | 1985-11-04 | 1990-02-06 | International Minerals & Chemical Corp. | Layered, compression molded device for the sustained release of a beneficial agent |
ATE71287T1 (de) * | 1986-06-13 | 1992-01-15 | Alza Corp | Aktivierung eines transdermalen drogenabgabesystems durch feuchtigkeit. |
US5344656A (en) * | 1986-09-12 | 1994-09-06 | Alza Corporation | Subsaturated transdermal therapeutic system having improved release characteristics |
US4908027A (en) * | 1986-09-12 | 1990-03-13 | Alza Corporation | Subsaturated transdermal therapeutic system having improved release characteristics |
US4761289A (en) * | 1986-10-10 | 1988-08-02 | International Minerals & Chemical Corp. | Sustained release implant and method for preparing same |
US5071656A (en) * | 1987-03-05 | 1991-12-10 | Alza Corporation | Delayed onset transdermal delivery device |
DE3743945A1 (de) * | 1987-09-01 | 1989-03-09 | Lohmann Gmbh & Co Kg | Vorrichtung zur abgabe von stoffen, verfahren zu ihrer herstellung sowie ihre verwendung |
US4917895A (en) * | 1987-11-02 | 1990-04-17 | Alza Corporation | Transdermal drug delivery device |
US4781924A (en) * | 1987-11-09 | 1988-11-01 | Alza Corporation | Transdermal drug delivery device |
US4837027A (en) * | 1987-11-09 | 1989-06-06 | Alza Corporation | Transdermal drug delivery device |
US5229148A (en) * | 1989-04-19 | 1993-07-20 | Wm. Wrigley Jr. Company | Method of combining active ingredients with polyvinyl acetates |
US5198251A (en) * | 1989-04-19 | 1993-03-30 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
US4978537A (en) * | 1989-04-19 | 1990-12-18 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
US5165944A (en) * | 1989-04-19 | 1992-11-24 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
US5108762A (en) * | 1989-04-19 | 1992-04-28 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
US5154939A (en) * | 1989-04-19 | 1992-10-13 | Wm. Wrigley Jr. Company | Use of salt to improve extrusion encapsulation of chewing gum ingredients |
US5091186A (en) * | 1989-08-15 | 1992-02-25 | Cygnus Therapeutic Systems | Biphasic transdermal drug delivery device |
US5124157A (en) * | 1989-08-18 | 1992-06-23 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
AU639645B2 (en) * | 1989-10-10 | 1993-07-29 | Wm. Wrigley Jr. Company | Gradual release structures made from fiber spinning techniques |
JPH03287525A (ja) * | 1990-04-03 | 1991-12-18 | Toichi Chikuma | 貼付鎮痛具 |
US5508038A (en) * | 1990-04-16 | 1996-04-16 | Alza Corporation | Polyisobutylene adhesives for transdermal devices |
JPH0421521U (fr) * | 1990-06-14 | 1992-02-24 | ||
US5128155A (en) * | 1990-12-20 | 1992-07-07 | Wm. Wrigley Jr. Company | Flavor releasing structures for chewing gum |
US5271736A (en) * | 1991-05-13 | 1993-12-21 | Applied Medical Research | Collagen disruptive morphology for implants |
CA2117351C (fr) * | 1992-01-13 | 1998-03-03 | Julian Belknap Lo | Methode de fabrication permettant d'accroitre la durete des comprimes |
US5443505A (en) * | 1993-11-15 | 1995-08-22 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
US5962011A (en) * | 1993-12-06 | 1999-10-05 | Schering-Plough Healthcare Products, Inc. | Device for delivery of dermatological ingredients |
US5633000A (en) * | 1994-06-23 | 1997-05-27 | Axxia Technologies | Subcutaneous implant |
US5819742A (en) * | 1996-11-06 | 1998-10-13 | Family Health International | Vaginal device for preventing conception or the transmission of sexually transmitted diseases, or both |
US6331311B1 (en) * | 1996-12-20 | 2001-12-18 | Alza Corporation | Injectable depot gel composition and method of preparing the composition |
US6039968A (en) * | 1997-06-24 | 2000-03-21 | Hoechst Marion Roussel | Intravaginal drug delivery device |
US6110500A (en) * | 1998-03-25 | 2000-08-29 | Temple University | Coated tablet with long term parabolic and zero-order release kinetics |
US20050175959A1 (en) * | 2000-03-14 | 2005-08-11 | Coll Partners Ltd. | System for the controlled delivery of an active material to a dental site |
IL135061A0 (en) * | 2000-03-14 | 2001-05-20 | Ahron Jodaikin | Strategic targeted fluoridation and chemical treatment of teeth |
US20030211974A1 (en) * | 2000-03-21 | 2003-11-13 | Brodbeck Kevin J. | Gel composition and methods |
DE60124285T3 (de) * | 2000-09-29 | 2011-03-17 | Cordis Corp., Miami Lakes | Beschichtete medizinische geräte |
MXPA04004665A (es) | 2001-11-14 | 2004-09-10 | Alza Corp | Composiciones de deposito inyectable y uso de los mismos. |
ES2329346T3 (es) * | 2001-11-14 | 2009-11-25 | Durect Corporation | Composicion de deposito inyectable. |
PT2561860T (pt) * | 2002-05-31 | 2018-05-08 | Titan Pharmaceuticals Inc | Dispositivo polimérico implantável para a libertação prolongada de buprenorfina |
US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
CN101057824A (zh) | 2002-07-31 | 2007-10-24 | 阿尔萨公司 | 可注射的多模式聚合物储库组合物以及其用途 |
NZ537955A (en) | 2002-07-31 | 2007-10-26 | Alza Corp | Injectable depot compositions and uses thereof |
ZA200507877B (en) | 2003-03-31 | 2007-01-31 | Titan Pharmaceuticals Inc | Implantable polymeric device for sustained release of dopamine agonist |
US7850453B2 (en) * | 2007-08-08 | 2010-12-14 | Coll Partners Ltd. | Reshapable device for fixation at a dental site |
USRE48948E1 (en) * | 2008-04-18 | 2022-03-01 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable polymer |
EP3415124A3 (fr) * | 2009-02-23 | 2019-02-27 | Mati Therapeutics Inc. | Implants lacrymaux |
US20110129516A1 (en) * | 2009-10-30 | 2011-06-02 | Aton Pharma, Inc. | Ocular drug delivery devices |
US9138308B2 (en) | 2010-02-03 | 2015-09-22 | Apollo Endosurgery, Inc. | Mucosal tissue adhesion via textured surface |
US9205577B2 (en) * | 2010-02-05 | 2015-12-08 | Allergan, Inc. | Porogen compositions, methods of making and uses |
AU2011252017B2 (en) * | 2010-05-11 | 2015-07-16 | Allergan, Inc. | Porogen compositions, methods of making and uses |
US9668844B2 (en) | 2013-11-06 | 2017-06-06 | Colldent Y.A Ltd | Device for fixation at a dental site |
US20160303242A1 (en) | 2013-12-09 | 2016-10-20 | Durect Corporation | Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same |
KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3402240A (en) * | 1957-06-25 | 1968-09-17 | Pfizer & Co C | Medicinal tablet and process of making same |
US3639583A (en) * | 1968-06-28 | 1972-02-01 | Goodrich Co B F | Biocidal elastomeric compositions |
US3700380A (en) * | 1970-10-01 | 1972-10-24 | Tecna Corp | Surface or lining compatible with blood or other tissue |
GB1412983A (en) * | 1971-11-30 | 1975-11-05 | Debell & Richardson | Method of producing porous plastic materials |
FR2183546B1 (fr) * | 1972-05-10 | 1975-06-20 | Servier Lab | |
JPS49118827A (fr) * | 1973-03-27 | 1974-11-13 | ||
JPS506709A (fr) * | 1973-05-18 | 1975-01-23 |
-
1974
- 1974-06-07 US US477297A patent/US3923939A/en not_active Expired - Lifetime
-
1975
- 1975-05-20 GB GB2165075A patent/GB1477545A/en not_active Expired
- 1975-05-28 SE SE7506099A patent/SE405803B/xx not_active IP Right Cessation
- 1975-06-03 CH CH714475A patent/CH611160A5/xx not_active IP Right Cessation
- 1975-06-05 DE DE2525061A patent/DE2525061C2/de not_active Expired
- 1975-06-06 IT IT68466/75A patent/IT1036192B/it active
- 1975-06-06 JP JP50068485A patent/JPS6043327B2/ja not_active Expired
- 1975-06-06 FR FR7517693A patent/FR2273515A1/fr active Granted
- 1975-06-06 MX MX001433U patent/MX3007E/es unknown
- 1975-06-06 CA CA228,740A patent/CA1047403A/fr not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0164311A2 (fr) * | 1984-05-10 | 1985-12-11 | Ciba-Geigy Ag | Dispositifs d'hydrogel contenant des substances actives dans lesquels le profil de concentration de la substance active contient un gradient de concentration sigmoidien pour une libération constante, leur fabrication et leur utilisation |
EP0164311A3 (en) * | 1984-05-10 | 1987-06-03 | Ciba-Geigy Ag | Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use |
Also Published As
Publication number | Publication date |
---|---|
CA1047403A (fr) | 1979-01-30 |
US3923939A (en) | 1975-12-02 |
MX3007E (es) | 1980-01-28 |
DE2525061A1 (de) | 1976-01-02 |
JPS5112920A (fr) | 1976-01-31 |
FR2273515B1 (fr) | 1980-02-15 |
CH611160A5 (fr) | 1979-05-31 |
JPS6043327B2 (ja) | 1985-09-27 |
IT1036192B (it) | 1979-10-30 |
SE405803B (sv) | 1979-01-08 |
SE7506099L (sv) | 1975-12-08 |
GB1477545A (en) | 1977-06-22 |
DE2525061C2 (de) | 1985-08-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |