FR2146978A1 - 5-phenyl thiazol-2-yl thioacetic acids and derivs - with antiinflammatory, analgesic and antipyretic activity - Google Patents

5-phenyl thiazol-2-yl thioacetic acids and derivs - with antiinflammatory, analgesic and antipyretic activity

Info

Publication number
FR2146978A1
FR2146978A1 FR7127814A FR7127814A FR2146978A1 FR 2146978 A1 FR2146978 A1 FR 2146978A1 FR 7127814 A FR7127814 A FR 7127814A FR 7127814 A FR7127814 A FR 7127814A FR 2146978 A1 FR2146978 A1 FR 2146978A1
Authority
FR
France
Prior art keywords
derivs
antiinflammatory
analgesic
antipyretic activity
phenyl thiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7127814A
Other languages
French (fr)
Other versions
FR2146978B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7127814A priority Critical patent/FR2146978A1/en
Publication of FR2146978A1 publication Critical patent/FR2146978A1/en
Application granted granted Critical
Publication of FR2146978B1 publication Critical patent/FR2146978B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Abstract

Cpds of formula (I) their salts with organic and inorganic bases and their esters with alcohols (C1-C4), where R1 is alkyl (C1-C3), phenyl; R2 is H or Cl. Prepd. by reaction of the appropriate thiazole-2-yl-thiols with chloro- or bromoacetic acids esters, or of the 2-chlorothiazoles with mercaptoacetic acid esters.
FR7127814A 1971-07-29 1971-07-29 5-phenyl thiazol-2-yl thioacetic acids and derivs - with antiinflammatory, analgesic and antipyretic activity Granted FR2146978A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7127814A FR2146978A1 (en) 1971-07-29 1971-07-29 5-phenyl thiazol-2-yl thioacetic acids and derivs - with antiinflammatory, analgesic and antipyretic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7127814A FR2146978A1 (en) 1971-07-29 1971-07-29 5-phenyl thiazol-2-yl thioacetic acids and derivs - with antiinflammatory, analgesic and antipyretic activity

Publications (2)

Publication Number Publication Date
FR2146978A1 true FR2146978A1 (en) 1973-03-09
FR2146978B1 FR2146978B1 (en) 1974-09-06

Family

ID=9081132

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7127814A Granted FR2146978A1 (en) 1971-07-29 1971-07-29 5-phenyl thiazol-2-yl thioacetic acids and derivs - with antiinflammatory, analgesic and antipyretic activity

Country Status (1)

Country Link
FR (1) FR2146978A1 (en)

Also Published As

Publication number Publication date
FR2146978B1 (en) 1974-09-06

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Legal Events

Date Code Title Description
ST Notification of lapse