FR2238485A1 - Anti-inflammatory and analgesic glyceryl esters - of substd 4-phenyl-butyric and 4-phenyl-4-oxobutyric acids - Google Patents

Anti-inflammatory and analgesic glyceryl esters - of substd 4-phenyl-butyric and 4-phenyl-4-oxobutyric acids

Info

Publication number
FR2238485A1
FR2238485A1 FR7425369A FR7425369A FR2238485A1 FR 2238485 A1 FR2238485 A1 FR 2238485A1 FR 7425369 A FR7425369 A FR 7425369A FR 7425369 A FR7425369 A FR 7425369A FR 2238485 A1 FR2238485 A1 FR 2238485A1
Authority
FR
France
Prior art keywords
phenyl
substd
analgesic
butyric
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7425369A
Other languages
French (fr)
Other versions
FR2238485B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ind C M
Original Assignee
Ind C M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind C M filed Critical Ind C M
Publication of FR2238485A1 publication Critical patent/FR2238485A1/en
Application granted granted Critical
Publication of FR2238485B1 publication Critical patent/FR2238485B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Title cpds. of formula (I) (where R1 = phenyl opt. substd. by halogen or 1-4C alkoxy or is cyclohexyl; R2 = H or halogen (esp. Cl); R3 and R4 = H or together = O) are prepd. by reacting a cpd. of formula (I; where -CH2-CH2-C(O)-O- etc. is -CH2-CH2-C(O)A in which A = Cl, OH or lower alkyl pref. lower alkyl when R3 + R4 = O) with a cpd. of formula (II) and reacting the prod. with a cpd. of formula (III) in the presence of H3BO3.
FR7425369A 1973-07-23 1974-07-22 Anti-inflammatory and analgesic glyceryl esters - of substd 4-phenyl-butyric and 4-phenyl-4-oxobutyric acids Granted FR2238485A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3507873 1973-07-23

Publications (2)

Publication Number Publication Date
FR2238485A1 true FR2238485A1 (en) 1975-02-21
FR2238485B1 FR2238485B1 (en) 1977-09-09

Family

ID=10373540

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7425369A Granted FR2238485A1 (en) 1973-07-23 1974-07-22 Anti-inflammatory and analgesic glyceryl esters - of substd 4-phenyl-butyric and 4-phenyl-4-oxobutyric acids

Country Status (5)

Country Link
JP (1) JPS5069052A (en)
BE (1) BE817940A (en)
DE (1) DE2434337A1 (en)
FR (1) FR2238485A1 (en)
NL (1) NL7409878A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016040225A1 (en) * 2014-09-09 2016-03-17 Bristol-Myers Squibb Company Phenyl-(aza)cycloalkyl carboxylic acid gpr120 modulators

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2592759B2 (en) * 1993-02-17 1997-03-19 日清紡績株式会社 Distributor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016040225A1 (en) * 2014-09-09 2016-03-17 Bristol-Myers Squibb Company Phenyl-(aza)cycloalkyl carboxylic acid gpr120 modulators
US10336684B2 (en) 2014-09-09 2019-07-02 Bristol=Myers Squibb Company Phenyl-(aza)cycloalkyl carboxylic acid GPR120 modulators

Also Published As

Publication number Publication date
BE817940A (en) 1975-01-22
FR2238485B1 (en) 1977-09-09
DE2434337A1 (en) 1975-02-13
JPS5069052A (en) 1975-06-09
NL7409878A (en) 1975-01-27

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Legal Events

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