FR2081464B1 - - Google Patents

Info

Publication number
FR2081464B1
FR2081464B1 FR7102796A FR7102796A FR2081464B1 FR 2081464 B1 FR2081464 B1 FR 2081464B1 FR 7102796 A FR7102796 A FR 7102796A FR 7102796 A FR7102796 A FR 7102796A FR 2081464 B1 FR2081464 B1 FR 2081464B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7102796A
Other languages
French (fr)
Other versions
FR2081464A1 (Direct
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702003714 external-priority patent/DE2003714C/de
Priority claimed from DE19702058086 external-priority patent/DE2058086A1/de
Priority claimed from DE19702058085 external-priority patent/DE2058085A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of FR2081464A1 publication Critical patent/FR2081464A1/fr
Application granted granted Critical
Publication of FR2081464B1 publication Critical patent/FR2081464B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR7102796A 1970-01-28 1971-01-28 Expired FR2081464B1 (Direct)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19702003714 DE2003714C (de) 1970-01-28 2 Piperazino 4 morpholino thieno eckige Klammer auf 3,2 d eckige Klammer zu pyrimidin und dessen Saureadditions salze
DE19702058086 DE2058086A1 (de) 1970-11-26 1970-11-26 Neue 4-Morpholino-thieno[3,2-d]pyrimidine,deren Salze und Verfahren zur Herstellung
DE19702058085 DE2058085A1 (de) 1970-11-26 1970-11-26 Neues Verfahren zur Herstellung von 4-Morpholino-thieno[3,2-d]pyrimidinen

Publications (2)

Publication Number Publication Date
FR2081464A1 FR2081464A1 (Direct) 1971-12-03
FR2081464B1 true FR2081464B1 (Direct) 1975-04-18

Family

ID=27182372

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7102796A Expired FR2081464B1 (Direct) 1970-01-28 1971-01-28

Country Status (9)

Country Link
US (1) US3763156A (Direct)
AU (1) AU2468871A (Direct)
BE (1) BE762135A (Direct)
ES (2) ES387553A1 (Direct)
FR (1) FR2081464B1 (Direct)
GB (1) GB1309182A (Direct)
IL (1) IL36079A0 (Direct)
NL (1) NL7101043A (Direct)
NO (1) NO129205B (Direct)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
US5280026A (en) * 1989-05-30 1994-01-18 Smithkline Beecham Intercredit B.V. Thienopyrimidines
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
EP1847543A1 (de) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
SI1874781T1 (sl) * 2006-04-19 2009-12-31 Boehringer Ingelheim Int Dihidrotienopirimidini za zdravljenje vnetnih obolenj
CA2650295C (en) * 2006-04-26 2015-12-29 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
JP5546240B2 (ja) 2006-04-26 2014-07-09 ジェネンテック， インコーポレイテッド 医薬化合物
BRPI0710874A2 (pt) 2006-04-26 2012-02-14 Hoffmann La Roche compostos de tienopirimidina, processos de produção dos referidos compostos, composições farmacêuticas contendo os mesmos, kit, produto, e usos dos compostos
CN101675053B (zh) * 2006-12-07 2014-03-12 健泰科生物技术公司 磷酸肌醇3-激酶抑制剂化合物及使用方法
TWI499420B (zh) * 2006-12-07 2015-09-11 Hoffmann La Roche 肌醇磷脂３-激酶抑制劑化合物及使用方法
CN101932587A (zh) 2007-09-24 2010-12-29 吉宁特有限公司 噻唑并嘧啶pi3k抑制剂化合物及使用方法
CN101827853A (zh) 2007-10-19 2010-09-08 贝林格尔.英格海姆国际有限公司 杂环取代的哌嗪子基-二氢噻吩并嘧啶
US8486948B2 (en) 2007-10-19 2013-07-16 Boehringer Ingelheim International Gmbh Piperazinodihydrothienopyrimidine derivatives
ES2381452T3 (es) * 2007-10-19 2012-05-28 Boehringer Ingelheim International Gmbh PIPERIDINO-DIHIDROTIENOPIRIMIDINAS sustituidas
ES2439705T3 (es) 2007-10-25 2014-01-24 Genentech, Inc. Proceso para la preparación de compuestos de tienopirimidina
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
BRPI1006189A2 (pt) 2009-03-12 2020-08-18 Genentech Inc uso de uma combinação terapêutica, formulação farmacêutica, artigo de manufatura, produto, método para determinar compostos a serem utilizados em combinação para o tratamento de uma malignidade hematopoiética e método para selecionar compostos a serem utilizados em combinação para o tratamento de câncer
WO2010136491A1 (en) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
SG175708A1 (en) * 2009-05-27 2011-12-29 Genentech Inc Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
EP2488178B1 (en) * 2009-10-12 2016-11-16 F.Hoffmann-La Roche Ag Combinations of a pi3k inhibitor and a mek inhibitor
CN103038643A (zh) 2010-04-16 2013-04-10 基因泰克公司 作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
EP2959014B1 (en) 2013-02-25 2019-11-13 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant
CN113423711B (zh) * 2018-10-01 2024-03-15 建新公司 作为udp糖基转移酶抑制剂的噻吩并[3,2-b]吡啶衍生物及其使用方法
GB202014736D0 (en) * 2020-09-18 2020-11-04 Imperial College Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
IL36079A0 (en) 1971-03-24
NL7101043A (Direct) 1971-07-30
NO129205B (Direct) 1974-03-11
ES387554A1 (es) 1974-01-16
ES387553A1 (es) 1974-01-16
GB1309182A (en) 1973-03-07
AU2468871A (en) 1972-07-27
BE762135A (fr) 1971-07-27
FR2081464A1 (Direct) 1971-12-03
US3763156A (en) 1973-10-02

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Legal Events

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ST Notification of lapse