FR1441575A - Nouveaux dérivés du spiro (4, 5) décane et leurs procédés de préparation - Google Patents
Nouveaux dérivés du spiro (4, 5) décane et leurs procédés de préparationInfo
- Publication number
- FR1441575A FR1441575A FR13521A FR13521A FR1441575A FR 1441575 A FR1441575 A FR 1441575A FR 13521 A FR13521 A FR 13521A FR 13521 A FR13521 A FR 13521A FR 1441575 A FR1441575 A FR 1441575A
- Authority
- FR
- France
- Prior art keywords
- decane
- spiro
- preparation processes
- new derivatives
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB16696/64A GB1100281A (en) | 1964-04-22 | 1964-04-22 | New spiro-decane derivatives and process for the preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
FR1441575A true FR1441575A (fr) | 1966-06-10 |
Family
ID=10081982
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR13521A Expired FR1441575A (fr) | 1964-04-22 | 1965-04-16 | Nouveaux dérivés du spiro (4, 5) décane et leurs procédés de préparation |
FR22211A Expired FR4463M (US07368562-20080506-C00024.png) | 1964-04-22 | 1965-06-25 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR22211A Expired FR4463M (US07368562-20080506-C00024.png) | 1964-04-22 | 1965-06-25 |
Country Status (9)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU638354B2 (en) * | 1990-09-06 | 1993-06-24 | Adir Et Compagnie | New spiro(4.5)decane compounds, a process for the preparation thereof and pharmaceutical compositions containing them |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL129025C (US07368562-20080506-C00024.png) * | 1965-04-29 | |||
US3542729A (en) * | 1968-03-19 | 1970-11-24 | Sankyo Co | Stabilization of synthetic polymers |
BE790675A (fr) * | 1971-10-29 | 1973-04-27 | Science Union & Cie | Nouveaux derives de l'oxa-1 diaza-3,8 spiro (4,5) decane |
US4244961A (en) * | 1978-10-26 | 1981-01-13 | Syntex (U.S.A.) Inc. | 1-Oxa-3,8-diazaspiro[4.5]decan-2-ones antihypertensive agents |
US4255432A (en) * | 1979-09-06 | 1981-03-10 | Syntex (U.S.A.) Inc. | 8-[2-3-Indolyl)ethyl]-1-oxa-3-,8-diazaspiro[4.5]decan-2-ones, pharmaceutical compositions thereof and methods of use thereof |
ES517622A0 (es) * | 1982-11-23 | 1983-12-16 | Faes | Procedimiento de preparacion de un nuevo espirodecano. |
YU150489A (sh) * | 1989-08-10 | 1992-12-21 | W.L. Gore & Co. Gmbh. | Uređaj za ispitivanje odevnih predmeta na nepromočivost |
HU204054B (en) * | 1989-08-10 | 1991-11-28 | Richter Gedeon Vegyeszet | Process for producing new 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives and pharmaceutical compositions comprising same |
FR2734265B1 (fr) * | 1995-05-17 | 1997-06-13 | Adir | Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant |
US6982251B2 (en) * | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
DK1363668T3 (da) * | 2001-01-26 | 2007-11-05 | Schering Corp | Kombinationer af galdesyrekompleksdanner(e) og sterolabsorptionsinhibitor(er) og behandling af vaskulære indikationer |
KR20080067717A (ko) * | 2001-01-26 | 2008-07-21 | 쉐링 코포레이션 | 스테롤 흡수 억제제와 혈액 조절제를 포함하는 혈관 질환의치료 또는 예방용 약제학적 조성물 |
US7071181B2 (en) * | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
CZ20032031A3 (cs) * | 2001-01-26 | 2003-12-17 | Schering Corporation | Farmaceutický prostředek |
AU2002247019C1 (en) * | 2001-01-26 | 2017-05-11 | Organon Llc | Combinations of peroxisome proliferator-activated receptor (PPAR) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications |
CZ305202B6 (cs) * | 2001-01-26 | 2015-06-10 | Merck Sharp & Dohme Corp. | Farmaceutický prostředek |
AR034204A1 (es) * | 2001-01-26 | 2004-02-04 | Schering Corp | Composiciones y combinaciones de acido nicotinico y derivados del mismo con inhibidor(es) de la absorcion de los esteroles, y el uso de los mismos para preparar medicamentos para el tratamiento para indicaciones vasculares |
ES2275007T3 (es) * | 2001-05-25 | 2007-06-01 | Schering Corporation | Uso de derivados de azetidinona sustitudos en el tratamiento de la enfermedad de alzeimer. |
DE10130020A1 (de) * | 2001-06-25 | 2003-12-04 | Gruenenthal Gmbh | Substituierte 1-Oxa-2,8-diaza-spiro[4.5]dec-2-en-derivate |
DE10146275A1 (de) | 2001-09-18 | 2003-04-24 | Gruenenthal Gmbh | Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz |
US7056906B2 (en) * | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
JP2005504091A (ja) * | 2001-09-21 | 2005-02-10 | シェーリング コーポレイション | ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置 |
US7053080B2 (en) * | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
HUP0401501A3 (en) * | 2001-09-21 | 2012-02-28 | Schering Corp | Treating or preventing vascular inflammation using pharmaceutical compositions containing sterol absorption inhibitor(s) |
US20030119808A1 (en) * | 2001-09-21 | 2003-06-26 | Schering Corporation | Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects |
MXPA05001958A (es) | 2002-08-19 | 2005-04-28 | Pfizer Prod Inc | Terapia de combinacion para enfermedades hiperproliferativas. |
EP1560579A1 (en) * | 2002-11-06 | 2005-08-10 | Schering Corporation | Cholesterol absorption inhibitors for the treatment of autoimmune disorders |
WO2004081002A1 (en) | 2003-03-07 | 2004-09-23 | Schering Corporation | Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia |
US7208486B2 (en) | 2003-03-07 | 2007-04-24 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
JP2006519869A (ja) * | 2003-03-07 | 2006-08-31 | シェーリング コーポレイション | 置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用 |
US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
EP1680189A2 (en) * | 2003-11-05 | 2006-07-19 | Schering Corporation | Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions |
AU2005211499A1 (en) | 2004-02-10 | 2005-08-18 | F. Hoffmann-La Roche Ag | Chemokine CCR5 receptor modulators |
US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
US8383660B2 (en) | 2006-03-10 | 2013-02-26 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
CN101646679A (zh) * | 2007-03-29 | 2010-02-10 | 弗·哈夫曼-拉罗切有限公司 | 杂环抗病毒化合物 |
DK2170930T3 (da) | 2007-06-04 | 2012-11-05 | Synergy Pharmaceuticals Inc | Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CN102766147B (zh) * | 2012-08-03 | 2015-07-15 | 无锡药兴医药科技有限公司 | 一种芬司匹利及其氢卤酸盐的制备方法 |
US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
KR102272746B1 (ko) | 2013-06-05 | 2021-07-08 | 보슈 헬스 아일랜드 리미티드 | 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법 |
GB201416346D0 (en) * | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Spirocyclic derivatives |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN113574055B (zh) | 2019-01-18 | 2024-07-23 | 阿斯利康(瑞典)有限公司 | Pcsk9抑制剂及其使用方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2437388A (en) * | 1948-03-09 | Z-oxazolidone compounds and proc | ||
US3193559A (en) * | 1965-07-06 | New derivatives of z-oxazolidinones | ||
US2500714A (en) * | 1944-10-30 | 1950-03-14 | Abbott Lab | 4-phenyl-1-alkyl isonipecotic acid lactones |
US3054794A (en) * | 1958-01-17 | 1962-09-18 | Us Vitamin Pharm Corp | Process for preparing 3-(aminoalkyl)-oxazolidine-2, 4-diones |
GB974134A (en) * | 1963-03-28 | 1964-11-04 | Science Union Et Compagnie Soc | Oxazolidinone derivatives |
-
0
- NL NL127065D patent/NL127065C/xx active
-
1964
- 1964-04-22 GB GB16696/64A patent/GB1100281A/en not_active Expired
-
1965
- 1965-03-27 SE SE4001/65A patent/SE307793B/xx unknown
- 1965-04-09 DE DE1620262A patent/DE1620262C3/de not_active Expired
- 1965-04-12 NL NL6504602A patent/NL6504602A/xx unknown
- 1965-04-14 US US447952A patent/US3399192A/en not_active Expired - Lifetime
- 1965-04-16 FR FR13521A patent/FR1441575A/fr not_active Expired
- 1965-04-21 BE BE662817A patent/BE662817A/xx unknown
- 1965-04-21 ES ES0312091A patent/ES312091A1/es not_active Expired
- 1965-04-22 CH CH558965A patent/CH454160A/fr unknown
- 1965-06-25 FR FR22211A patent/FR4463M/fr not_active Expired
-
1968
- 1968-12-28 ES ES361975A patent/ES361975A2/es not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU638354B2 (en) * | 1990-09-06 | 1993-06-24 | Adir Et Compagnie | New spiro(4.5)decane compounds, a process for the preparation thereof and pharmaceutical compositions containing them |
Also Published As
Publication number | Publication date |
---|---|
BE662817A (US07368562-20080506-C00024.png) | 1965-10-21 |
DE1620262B2 (de) | 1979-10-11 |
NL6504602A (US07368562-20080506-C00024.png) | 1965-10-25 |
GB1100281A (en) | 1968-01-24 |
DE1620262C3 (de) | 1980-07-03 |
FR4463M (US07368562-20080506-C00024.png) | 1966-09-26 |
US3399192A (en) | 1968-08-27 |
ES312091A1 (es) | 1965-10-01 |
SE307793B (US07368562-20080506-C00024.png) | 1969-01-20 |
CH454160A (fr) | 1968-04-15 |
DE1620262A1 (de) | 1972-03-23 |
ES361975A2 (es) | 1971-01-16 |
NL127065C (US07368562-20080506-C00024.png) |
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