FR04C0028I2 - - Google Patents
Info
- Publication number
- FR04C0028I2 FR04C0028I2 FR04C0028C FR04C0028C FR04C0028I2 FR 04C0028 I2 FR04C0028 I2 FR 04C0028I2 FR 04C0028 C FR04C0028 C FR 04C0028C FR 04C0028 C FR04C0028 C FR 04C0028C FR 04C0028 I2 FR04C0028 I2 FR 04C0028I2
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Plant Pathology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75720596A | 1996-11-27 | 1996-11-27 | |
| PCT/US1997/019041 WO1998023761A1 (en) | 1996-11-27 | 1997-10-20 | HUMANIZED ANTI-CD11a ANTIBODIES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR04C0028I1 FR04C0028I1 (cs) | 2005-02-11 |
| FR04C0028I2 true FR04C0028I2 (cs) | 2007-10-26 |
Family
ID=25046834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR04C0028C Active FR04C0028I2 (cs) | 1996-11-27 | 2004-12-10 |
Country Status (17)
| Country | Link |
|---|---|
| EP (2) | EP0941344B1 (cs) |
| JP (2) | JP3778945B2 (cs) |
| KR (1) | KR100532178B1 (cs) |
| AR (1) | AR008919A1 (cs) |
| AT (1) | ATE267257T1 (cs) |
| AU (1) | AU731817C (cs) |
| CA (1) | CA2272842C (cs) |
| DE (3) | DE122004000047I2 (cs) |
| DK (2) | DK1516629T3 (cs) |
| ES (1) | ES2221045T3 (cs) |
| FR (1) | FR04C0028I2 (cs) |
| IL (3) | IL130143A0 (cs) |
| LU (1) | LU91122I2 (cs) |
| NL (1) | NL300163I2 (cs) |
| PT (1) | PT941344E (cs) |
| WO (1) | WO1998023761A1 (cs) |
| ZA (1) | ZA979599B (cs) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7122636B1 (en) | 1997-02-21 | 2006-10-17 | Genentech, Inc. | Antibody fragment-polymer conjugates and uses of same |
| SI1135498T1 (sl) | 1998-11-18 | 2008-06-30 | Genentech Inc | Variante protitelesa z višjo vezavno afiniteto vprimerjavi z izvirnimi protitelesi |
| EP1135498B1 (en) | 1998-11-18 | 2008-01-23 | Genentech, Inc. | Antibody variants with higher binding affinity compared to parent antibodies |
| US6582698B1 (en) | 1999-03-19 | 2003-06-24 | Genentech, Inc. | Treatment method |
| EP1163003B1 (en) | 1999-03-19 | 2009-08-12 | Genentech, Inc. | Treatment of lfa-1 associated disorders with increasing doses of lfa-1 antagonist |
| CN1409639A (zh) * | 1999-12-14 | 2003-04-09 | 杰南技术公司 | 应用TNF－α拮抗剂和LFA－1拮抗剂治疗LFA－1或TNF－α介导的疾病 |
| US7560275B2 (en) | 1999-12-30 | 2009-07-14 | Vbi Technologies, L.L.C. | Compositions and methods for generating skin |
| US7575921B2 (en) | 1999-12-30 | 2009-08-18 | Vbi Technologies, L.L.C. | Spore-like cells and uses thereof |
| WO2001051084A1 (en) * | 2000-01-14 | 2001-07-19 | Genentech, Inc. | Diagnosis and treatment of hepatic inflammatory disorders by inhibiting the binding of lfa-1 to icam-1 |
| ATE448306T1 (de) * | 2000-09-01 | 2009-11-15 | Blood Res Center | Veränderte, in gewünschter konformation stabilisierte polypeptide und verfahren zu deren herstellung |
| WO2002057428A1 (en) | 2000-10-30 | 2002-07-25 | University Of Massachusetts | Isolation of spore-like cells from tissues exposed to extreme conditions |
| DE60325334D1 (de) | 2002-02-05 | 2009-01-29 | Genentech Inc | Proteinaufreinigung |
| WO2003102132A2 (en) | 2002-04-26 | 2003-12-11 | Genetech, Inc. | Non-affinity purification of proteins |
| AU2003270439B2 (en) | 2002-09-11 | 2009-09-24 | Genentech, Inc. | Novel composition and methods for the treatment of immune related diseases |
| US7388079B2 (en) | 2002-11-27 | 2008-06-17 | The Regents Of The University Of California | Delivery of pharmaceutical agents via the human insulin receptor |
| MXPA05011406A (es) * | 2003-04-23 | 2005-12-12 | Medarex Inc | Anticuerpos humanizados para el receptor-1 de interferon alfa (ifnar-1). |
| PT3095793T (pt) | 2003-07-28 | 2020-05-04 | Genentech Inc | Redução da lixiviação de proteína a durante a cromatografia por afinidade com proteína a |
| US7927591B2 (en) * | 2004-02-19 | 2011-04-19 | The Cbr Institute For Biomedical Research, Inc. | Conformation specific antibodies |
| DK1716181T3 (da) | 2004-02-19 | 2010-03-01 | Genentech Inc | CDR-reparerede antistoffer |
| CA2568570A1 (en) * | 2004-06-09 | 2005-12-29 | Genentech, Inc. | Method of treating granuloma annulare or sarcoid |
| US7662926B2 (en) | 2004-09-02 | 2010-02-16 | Genentech, Inc. | Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor |
| US7655229B2 (en) | 2004-09-02 | 2010-02-02 | Chan Andrew C | Anti-FC-gamma RIIB receptor antibody and uses therefor |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| FR2902799B1 (fr) | 2006-06-27 | 2012-10-26 | Millipore Corp | Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide |
| US8163886B2 (en) | 2006-12-21 | 2012-04-24 | Emd Millipore Corporation | Purification of proteins |
| US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
| US8569464B2 (en) | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
| ATE526017T1 (de) | 2007-01-22 | 2011-10-15 | Genentech Inc | Abscheidung von polyelektrolyten und reinigung von antikörpern |
| AU2008275229B2 (en) | 2007-07-09 | 2014-11-06 | Genentech, Inc. | Prevention of disulfide bond reduction during recombinant production of polypeptides |
| AR069097A1 (es) | 2007-10-30 | 2009-12-30 | Genentech Inc | Purificacion de anticuerpos por cromatografia de intercambio cationico |
| SG10201402815VA (en) | 2008-04-09 | 2014-09-26 | Genentech Inc | Novel compositions and methods for the treatment of immune related diseases |
| WO2009151514A1 (en) | 2008-06-11 | 2009-12-17 | Millipore Corporation | Stirred tank bioreactor |
| EP2145901B1 (en) | 2008-07-18 | 2012-11-14 | Technische Universität Braunschweig | Recombinant anti-MUC1 antibodies |
| EP2848625B1 (en) | 2008-08-14 | 2019-07-31 | Genentech, Inc. | Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography |
| WO2010030670A2 (en) | 2008-09-10 | 2010-03-18 | Genentech, Inc. | Compositions and methods for the prevention of oxidative degradation of proteins |
| SG171764A1 (en) | 2008-12-16 | 2011-07-28 | Millipore Corp | Purification of proteins |
| ES2749232T3 (es) | 2008-12-16 | 2020-03-19 | Emd Millipore Corp | Reactor de tanque agitado y procedimiento |
| WO2010099273A1 (en) | 2009-02-27 | 2010-09-02 | Genentech, Inc. | Methods and compositions for protein labelling |
| HUE048980T2 (hu) | 2009-08-11 | 2020-08-28 | Hoffmann La Roche | Fehérjék elõállítása glutaminmentes sejttenyésztõ táptalajban |
| HRP20200581T1 (hr) | 2009-09-01 | 2020-07-10 | F. Hoffmann - La Roche Ag | Pojačano pročišćavanje proteina kroz eluiranje modificiranog proteina a |
| EP2499240A1 (en) | 2009-11-12 | 2012-09-19 | Vbi Technologies, LLC | Subpopulations of spore-like cells and uses thereof |
| US20120309056A1 (en) | 2010-02-04 | 2012-12-06 | Leon Arnaud | Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells |
| WO2011119487A2 (en) | 2010-03-22 | 2011-09-29 | Genentech, Inc. | Compositions and methods useful for stabilizing protein-containing formulations |
| MX2012012743A (es) | 2010-05-03 | 2012-11-23 | Genentech Inc | Composiciones y metodos utiles para reducir la viscosidad de formulaciones que contienen proteina. |
| JP5612761B2 (ja) | 2010-05-17 | 2014-10-22 | イー・エム・デイー・ミリポア・コーポレイシヨン | 生体分子の精製のための刺激応答性ポリマー |
| SI2576580T1 (sl) | 2010-05-28 | 2016-12-30 | F. Hoffmann-La Roche Ag | Znižanje nivoja laktata in zvišanje produkcije polipeptida z znižanjem ravni izražanja laktat-dehidrogenaze in piruvat-dehidrogenaza-kinaze |
| KR102058307B1 (ko) | 2010-06-24 | 2019-12-20 | 제넨테크, 인크. | 단백질-함유 제제를 안정화시키기 위한 알킬글리코시드 함유 조성물 및 방법 |
| CN104474546A (zh) | 2010-08-13 | 2015-04-01 | 弗·哈夫曼-拉罗切有限公司 | 用于疾病治疗的针对IL-1β和IL-18的抗体 |
| WO2012030512A1 (en) | 2010-09-03 | 2012-03-08 | Percivia Llc. | Flow-through protein purification process |
| WO2012088272A1 (en) * | 2010-12-21 | 2012-06-28 | Duke University | Methods and compositions combining immunotherapy with monocyte activation |
| WO2012095514A1 (en) | 2011-01-14 | 2012-07-19 | Vivalis | Recombinant protein production system |
| WO2013096322A1 (en) | 2011-12-22 | 2013-06-27 | Genentech, Inc | Ion exchange membrane chromatography |
| WO2013148249A1 (en) | 2012-03-27 | 2013-10-03 | Genentech, Inc. | Improved harvest operations for recombinant proteins |
| CN108187043A (zh) | 2012-05-18 | 2018-06-22 | 基因泰克公司 | 高浓度单克隆抗体配制剂 |
| WO2014100095A1 (en) | 2012-12-19 | 2014-06-26 | Genentech, Inc. | Methods and compositions for radiohalogen protein labeling |
| EP3019523A4 (en) | 2013-07-09 | 2016-12-28 | Annexon Inc | METHOD FOR THE TREATMENT OF MORBUS ALZHEIMER AND MORBUS HUNTINGTON |
| LT3021869T (lt) | 2013-07-16 | 2020-10-12 | F. Hoffmann-La Roche Ag | Vėžio gydymo būdai, naudojant pd-1 ašį surišančius antagonistus ir tigit inhibitorius |
| EP3166401B1 (en) | 2014-07-09 | 2020-08-19 | F. Hoffmann-La Roche AG | Ph adjustment to improve thaw recovery of cell banks |
| LT3215527T (lt) | 2014-11-05 | 2025-04-10 | Annexon, Inc. | Humanizuoti antikūnai prieš komplemento faktorių c1q ir jų panaudojimas |
| US10946095B2 (en) | 2015-09-02 | 2021-03-16 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Antibodies specific to human T-cell immunoglobulin and ITIM domain (TIGIT) |
| IL319106A (en) | 2015-09-25 | 2025-04-01 | Genentech Inc | Anti-TIGIT antibodies and methods of use |
| SG11201803703UA (en) | 2015-11-24 | 2018-06-28 | Annexon Inc | Anti-complement factor c1q fab fragments and uses thereof |
| BR112018070139A2 (pt) | 2016-03-29 | 2019-02-05 | Geltor Inc | expressão de proteínas em bactérias gram-negativas em que a razão entre o volume periplasmático e o volume citoplasmático é entre 0,5:1 e 10:1 |
| BR112019012686A2 (pt) | 2016-12-22 | 2019-11-19 | Genentech Inc | métodos e formulações para a redução do tempo de reconstituição de polipeptídeos liofilizados |
| US11180541B2 (en) | 2017-09-28 | 2021-11-23 | Geltor, Inc. | Recombinant collagen and elastin molecules and uses thereof |
| MX2020013633A (es) | 2018-07-03 | 2021-03-25 | Bristol Myers Squibb Co | Metodos para producir proteinas recombinantes. |
| US12415980B2 (en) | 2018-10-10 | 2025-09-16 | Boehringer Ingelheim International Gmbh | Method for membrane gas transfer in high density bioreactor culture |
| JP7589168B2 (ja) | 2019-04-01 | 2024-11-25 | ジェネンテック， インコーポレイテッド | タンパク質含有製剤を安定化するための組成物および方法 |
| JP2022526434A (ja) | 2019-04-12 | 2022-05-24 | ジェルター， インコーポレイテッド | 組換えエラスチンおよびその産生 |
| EP4007808A1 (en) | 2019-08-01 | 2022-06-08 | Bristol-Myers Squibb Company | Methods of improving protein productivity in fed-batch cell cultures |
| EP4217383A1 (en) | 2020-09-22 | 2023-08-02 | Bristol-Myers Squibb Company | Methods for producing therapeutic proteins |
| WO2023015234A1 (en) | 2021-08-05 | 2023-02-09 | Bristol-Myers Squibb Company | Cell culture methods for producing therapeutic proteins |
| US20240390869A1 (en) | 2021-09-21 | 2024-11-28 | Bristol-Myers Squibb Company | Methods of controlling the level of dissolved oxygen (do) in a solution comprising a recombinant protein in a storage container |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ236792A (en) * | 1990-01-19 | 1993-05-26 | Merck & Co Inc | Recombinant human anti-cd18 antibody, murine 1b4 heavy or light chain variable region, dna, vectors, mammalian host and pharmaceutical compositions |
| US6096871A (en) * | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
-
1997
- 1997-10-20 DE DE1997629209 patent/DE122004000047I2/de active Active
- 1997-10-20 IL IL13014397A patent/IL130143A0/xx active IP Right Grant
- 1997-10-20 KR KR10-1999-7004671A patent/KR100532178B1/ko not_active Expired - Lifetime
- 1997-10-20 WO PCT/US1997/019041 patent/WO1998023761A1/en not_active Application Discontinuation
- 1997-10-20 CA CA2272842A patent/CA2272842C/en not_active Expired - Lifetime
- 1997-10-20 EP EP97912841A patent/EP0941344B1/en not_active Expired - Lifetime
- 1997-10-20 DK DK04004941.3T patent/DK1516629T3/da active
- 1997-10-20 JP JP52464598A patent/JP3778945B2/ja not_active Expired - Lifetime
- 1997-10-20 DE DE69729209T patent/DE69729209T2/de not_active Expired - Lifetime
- 1997-10-20 PT PT97912841T patent/PT941344E/pt unknown
- 1997-10-20 DK DK97912841T patent/DK0941344T3/da active
- 1997-10-20 AT AT97912841T patent/ATE267257T1/de active
- 1997-10-20 ES ES97912841T patent/ES2221045T3/es not_active Expired - Lifetime
- 1997-10-20 AU AU49929/97A patent/AU731817C/en not_active Expired
- 1997-10-20 EP EP04004941A patent/EP1516629B1/en not_active Expired - Lifetime
- 1997-10-20 DE DE200412000047 patent/DE122004000047I1/de active Pending
- 1997-10-27 ZA ZA979599A patent/ZA979599B/xx unknown
- 1997-11-04 AR ARP970105146A patent/AR008919A1/es active IP Right Grant
-
1999
- 1999-05-26 IL IL130143A patent/IL130143A/en not_active IP Right Cessation
-
2004
- 2004-11-10 LU LU91122C patent/LU91122I2/fr unknown
- 2004-11-12 NL NL300163C patent/NL300163I2/nl unknown
- 2004-12-10 FR FR04C0028C patent/FR04C0028I2/fr active Active
-
2005
- 2005-08-02 JP JP2005224609A patent/JP4309383B2/ja not_active Expired - Lifetime
-
2006
- 2006-05-11 IL IL175583A patent/IL175583A0/en not_active IP Right Cessation