FI97884B - Menetelmä uusien terapeuttisesti käyttökelpoisten 3,4-dihydroksi-2,5-dihydrofuranonien valmistamiseksi - Google Patents

Menetelmä uusien terapeuttisesti käyttökelpoisten 3,4-dihydroksi-2,5-dihydrofuranonien valmistamiseksi

Info

Publication number
FI97884B
FI97884B FI911282A FI911282A FI97884B FI 97884 B FI97884 B FI 97884B FI 911282 A FI911282 A FI 911282A FI 911282 A FI911282 A FI 911282A FI 97884 B FI97884 B FI 97884B
Authority
FI
Finland
Prior art keywords
dihydroxy
preparation
dihydrofuranones
therapeutically useful
new therapeutically
Prior art date
Application number
FI911282A
Other languages
English (en)
Swedish (sv)
Other versions
FI97884C (fi
FI911282A0 (fi
FI911282A (fi
Inventor
Gilbert Marciniak
J Martin Grisar
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of FI911282A0 publication Critical patent/FI911282A0/fi
Publication of FI911282A publication Critical patent/FI911282A/fi
Application granted granted Critical
Publication of FI97884B publication Critical patent/FI97884B/fi
Publication of FI97884C publication Critical patent/FI97884C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
FI911282A 1990-03-16 1991-03-15 Menetelmä uusien terapeuttisesti käyttökelpoisten 3,4-dihydroksi-2,5-dihydrofuranonien valmistamiseksi FI97884C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90400731 1990-03-16
EP90400731A EP0446539A1 (en) 1990-03-16 1990-03-16 Novel ascorbic acid derivatives

Publications (4)

Publication Number Publication Date
FI911282A0 FI911282A0 (fi) 1991-03-15
FI911282A FI911282A (fi) 1991-09-17
FI97884B true FI97884B (fi) 1996-11-29
FI97884C FI97884C (fi) 1997-03-10

Family

ID=8205691

Family Applications (1)

Application Number Title Priority Date Filing Date
FI911282A FI97884C (fi) 1990-03-16 1991-03-15 Menetelmä uusien terapeuttisesti käyttökelpoisten 3,4-dihydroksi-2,5-dihydrofuranonien valmistamiseksi

Country Status (21)

Country Link
US (1) US5175188A (fi)
EP (2) EP0446539A1 (fi)
JP (1) JP3029055B2 (fi)
KR (1) KR0171190B1 (fi)
CN (1) CN1034415C (fi)
AT (1) ATE137230T1 (fi)
AU (1) AU632907B2 (fi)
CA (1) CA2038416C (fi)
DE (1) DE69118955T2 (fi)
DK (1) DK0447325T5 (fi)
ES (1) ES2089159T3 (fi)
FI (1) FI97884C (fi)
GR (1) GR3020411T3 (fi)
HU (1) HU208004B (fi)
IE (1) IE910879A1 (fi)
IL (1) IL97574A (fi)
NO (1) NO177705C (fi)
NZ (1) NZ237400A (fi)
PT (1) PT97041B (fi)
TW (1) TW213455B (fi)
ZA (1) ZA911994B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU214331B (hu) * 1992-06-17 1998-03-02 Gyógyszerkutató Intézet Kft. Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
US5559251A (en) * 1993-02-05 1996-09-24 Pliva, Farmaceutska Derivatives of amino-ascorbic acid, the processes for their preparation and use
HRP930131A2 (en) * 1993-02-05 1997-02-28 Bozidar Suskovic Amino-ascorbic acid derivatives, process for the preparation and use thereof
FR2946252B1 (fr) * 2009-06-08 2011-07-29 Fabre Pierre Dermo Cosmetique Bis esters d'acide gras insature sur l'acide ascorbique et leurs utilisations cosmetiques

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4368330A (en) * 1981-04-30 1983-01-11 Pfizer Inc. Derivatives of L-ascorbic acid and D-erythorbic acid
RO86439B (ro) * 1982-01-15 1985-03-31 Eli Lilly And Company Procedeu pentru prepararea unor derivati de acid ascorbic
ZA852614B (en) * 1985-05-17 1986-10-09 Takeda Chemical Industries, Ltd. Ascorbic acid ethers and their production
JP2515556B2 (ja) * 1986-08-29 1996-07-10 武田薬品工業株式会社 ヒドロキシブテノライド誘導体およびその製造法
IT1215325B (it) * 1987-01-07 1990-02-08 Barisintex Sa Composti antagonisti di recettori -h2 e procedimento per la loro preparazione.

Also Published As

Publication number Publication date
NO911051L (no) 1991-09-17
FI97884C (fi) 1997-03-10
ZA911994B (en) 1991-12-24
EP0447325B1 (en) 1996-04-24
FI911282A0 (fi) 1991-03-15
CA2038416A1 (en) 1991-09-17
HUT56559A (en) 1991-09-30
CA2038416C (en) 2003-03-11
US5175188A (en) 1992-12-29
NO911051D0 (no) 1991-03-15
IL97574A0 (en) 1992-06-21
TW213455B (fi) 1993-09-21
JPH04234869A (ja) 1992-08-24
PT97041A (pt) 1991-10-31
IE910879A1 (en) 1991-09-25
HU208004B (en) 1993-07-28
FI911282A (fi) 1991-09-17
EP0447325A1 (en) 1991-09-18
NO177705B (no) 1995-07-31
KR910016732A (ko) 1991-11-05
CN1054978A (zh) 1991-10-02
IL97574A (en) 1995-10-31
KR0171190B1 (ko) 1999-02-01
ATE137230T1 (de) 1996-05-15
GR3020411T3 (en) 1996-09-30
EP0446539A1 (en) 1991-09-18
AU632907B2 (en) 1993-01-14
DK0447325T5 (da) 1996-05-28
NZ237400A (en) 1993-05-26
PT97041B (pt) 1998-07-31
DE69118955D1 (de) 1996-05-30
CN1034415C (zh) 1997-04-02
ES2089159T3 (es) 1996-10-01
NO177705C (no) 1995-11-08
DE69118955T2 (de) 1996-09-19
JP3029055B2 (ja) 2000-04-04
AU7287891A (en) 1991-10-10

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: MERRELL DOW PHARMACEUTICALS INC.

BB Publication of examined application
MA Patent expired