FI972660A - Piperatsini-2,5-dionijohdannaiset monilääke resistanssi modulaattoreina - Google Patents
Piperatsini-2,5-dionijohdannaiset monilääke resistanssi modulaattoreina Download PDFInfo
- Publication number
- FI972660A FI972660A FI972660A FI972660A FI972660A FI 972660 A FI972660 A FI 972660A FI 972660 A FI972660 A FI 972660A FI 972660 A FI972660 A FI 972660A FI 972660 A FI972660 A FI 972660A
- Authority
- FI
- Finland
- Prior art keywords
- piperazine
- multidrug resistance
- dione derivatives
- resistance modulators
- modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9426224.3A GB9426224D0 (en) | 1994-12-23 | 1994-12-23 | Pharmaceutical compounds |
| PCT/GB1995/003027 WO1996020190A1 (en) | 1994-12-23 | 1995-12-22 | Piperazine 2,5 dione derivatives as modulators of multi-drug resistance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI972660A0 FI972660A0 (fi) | 1997-06-19 |
| FI972660A true FI972660A (fi) | 1997-08-22 |
Family
ID=10766589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI972660A FI972660A (fi) | 1994-12-23 | 1997-06-19 | Piperatsini-2,5-dionijohdannaiset monilääke resistanssi modulaattoreina |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0799222A1 (zh) |
| JP (1) | JPH10511384A (zh) |
| CN (1) | CN1175253A (zh) |
| AU (1) | AU698828B2 (zh) |
| BG (1) | BG101602A (zh) |
| BR (1) | BR9510410A (zh) |
| CA (1) | CA2207500A1 (zh) |
| CZ (1) | CZ190097A3 (zh) |
| FI (1) | FI972660A (zh) |
| GB (1) | GB9426224D0 (zh) |
| HU (1) | HUT77943A (zh) |
| IL (1) | IL116525A0 (zh) |
| NO (1) | NO972937D0 (zh) |
| NZ (1) | NZ297847A (zh) |
| PL (1) | PL320916A1 (zh) |
| SK (1) | SK83697A3 (zh) |
| TW (1) | TW358094B (zh) |
| WO (1) | WO1996020190A1 (zh) |
| ZA (1) | ZA9510909B (zh) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9717576D0 (en) * | 1997-08-19 | 1997-10-22 | Xenova Ltd | Pharmaceutical compounds |
| HUP0001531A3 (en) * | 1996-10-18 | 2000-09-28 | Xenova Ltd Slough | Anthranilic acid derivatives as multi drug resistance modulators |
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| EA200100428A1 (ru) | 1998-10-08 | 2001-10-22 | Смитклайн Бичам Плс | Производные тетрагидробензазепина, полезные в качестве модуляторов допаминовых d3 рецепторов (антипсихотические агенты) |
| NZ519989A (en) * | 2000-01-18 | 2004-05-28 | Nereus Pharmaceuticals Inc | Cell division inhibitors and process for producing the same |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| US7935704B2 (en) | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| DE60316688T2 (de) | 2002-08-02 | 2008-07-17 | Nereus Pharmaceuticals, Inc., San Diego | Dehydrophenylahistine und analoge davon sowie ein verfahren zur herstellung von dehydrophenylahistinen und analogen davon |
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| US8129527B2 (en) | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| CN103396372B (zh) * | 2013-08-09 | 2015-05-20 | 中国科学院南海海洋研究所 | 一类2,5-二酮哌嗪衍生物及其制备方法和在制备抗海洋污损生物防除剂中的应用 |
| BR112017018954A2 (pt) | 2015-03-06 | 2018-05-15 | Beyondspring Pharmaceuticals, Inc. | uso de forma mutante de proteína ras e método para tratar câncer |
| CA2978679A1 (en) | 2015-03-06 | 2016-09-15 | Beyondspring Pharmaceuticals, Inc. | Method of treating a brain tumor |
| CN113735834B (zh) | 2015-07-13 | 2023-06-13 | 大连万春布林医药有限公司 | 普那布林组合物 |
| IL260933B2 (en) | 2016-02-08 | 2023-04-01 | Beyondspring Pharmaceuticals Inc | Preparations containing tocorsol or its analogues |
| KR20190015361A (ko) | 2016-06-06 | 2019-02-13 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 호중구감소증을 줄이는 조성물 및 방법 |
| WO2018129381A1 (en) | 2017-01-06 | 2018-07-12 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
| SG11201907023UA (en) | 2017-02-01 | 2019-08-27 | Beyondspring Pharmaceuticals Inc | Method of reducing neutropenia |
| KR20200112881A (ko) | 2018-01-24 | 2020-10-05 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 플리나불린의 투여를 통해 혈소판감소증을 감소시키는 조성물 및 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE152443T1 (de) * | 1992-07-10 | 1997-05-15 | Glaxo Lab Sa | Anilide-derivate |
| GB9217331D0 (en) * | 1992-08-14 | 1992-09-30 | Xenova Ltd | Pharmaceutical compounds |
-
1994
- 1994-12-23 GB GBGB9426224.3A patent/GB9426224D0/en active Pending
-
1995
- 1995-12-21 ZA ZA9510909A patent/ZA9510909B/xx unknown
- 1995-12-22 HU HU9800398A patent/HUT77943A/hu unknown
- 1995-12-22 IL IL11652595A patent/IL116525A0/xx unknown
- 1995-12-22 BR BR9510410-0A patent/BR9510410A/pt not_active Application Discontinuation
- 1995-12-22 SK SK836-97A patent/SK83697A3/sk unknown
- 1995-12-22 AU AU43100/96A patent/AU698828B2/en not_active Ceased
- 1995-12-22 CA CA002207500A patent/CA2207500A1/en not_active Abandoned
- 1995-12-22 CN CN95197672A patent/CN1175253A/zh active Pending
- 1995-12-22 PL PL95320916A patent/PL320916A1/xx unknown
- 1995-12-22 CZ CZ971900A patent/CZ190097A3/cs unknown
- 1995-12-22 JP JP8520301A patent/JPH10511384A/ja active Pending
- 1995-12-22 EP EP95941797A patent/EP0799222A1/en not_active Withdrawn
- 1995-12-22 WO PCT/GB1995/003027 patent/WO1996020190A1/en not_active Application Discontinuation
- 1995-12-22 NZ NZ297847A patent/NZ297847A/en unknown
- 1995-12-23 TW TW084113836A patent/TW358094B/zh active
-
1997
- 1997-06-11 BG BG101602A patent/BG101602A/xx unknown
- 1997-06-19 FI FI972660A patent/FI972660A/fi unknown
- 1997-06-23 NO NO972937A patent/NO972937D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB9426224D0 (en) | 1995-02-22 |
| SK83697A3 (en) | 1998-05-06 |
| JPH10511384A (ja) | 1998-11-04 |
| IL116525A0 (en) | 1996-03-31 |
| FI972660A0 (fi) | 1997-06-19 |
| CZ190097A3 (cs) | 1998-01-14 |
| EP0799222A1 (en) | 1997-10-08 |
| CA2207500A1 (en) | 1996-07-04 |
| PL320916A1 (en) | 1997-11-10 |
| ZA9510909B (en) | 1996-08-30 |
| BG101602A (en) | 1998-02-27 |
| WO1996020190A1 (en) | 1996-07-04 |
| CN1175253A (zh) | 1998-03-04 |
| BR9510410A (pt) | 1999-09-08 |
| AU698828B2 (en) | 1998-11-05 |
| AU4310096A (en) | 1996-07-19 |
| NO972937L (no) | 1997-06-23 |
| NZ297847A (en) | 1999-04-29 |
| TW358094B (en) | 1999-05-11 |
| NO972937D0 (no) | 1997-06-23 |
| HUT77943A (hu) | 1998-12-28 |
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