FI971956A - Hermosolujen lisääntymisen säännöstely - Google Patents
Hermosolujen lisääntymisen säännöstely Download PDFInfo
- Publication number
- FI971956A FI971956A FI971956A FI971956A FI971956A FI 971956 A FI971956 A FI 971956A FI 971956 A FI971956 A FI 971956A FI 971956 A FI971956 A FI 971956A FI 971956 A FI971956 A FI 971956A
- Authority
- FI
- Finland
- Prior art keywords
- regulation
- neuronal proliferation
- neuronal
- proliferation
- Prior art date
Links
- 230000007511 neuronal proliferation Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/90—Polysaccharides
- C12N2501/91—Heparin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33873094A | 1994-11-14 | 1994-11-14 | |
PCT/CA1995/000637 WO1996015226A1 (en) | 1994-11-14 | 1995-11-14 | Regulation of neural stem cell proliferation |
Publications (2)
Publication Number | Publication Date |
---|---|
FI971956A0 FI971956A0 (fi) | 1997-05-07 |
FI971956A true FI971956A (fi) | 1997-07-04 |
Family
ID=23325929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI971956A FI971956A (fi) | 1994-11-14 | 1997-05-07 | Hermosolujen lisääntymisen säännöstely |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0792350A1 (no) |
JP (1) | JPH10509592A (no) |
KR (1) | KR970707272A (no) |
CN (1) | CN1170435A (no) |
AU (1) | AU716811B2 (no) |
FI (1) | FI971956A (no) |
NO (1) | NO972171L (no) |
WO (1) | WO1996015226A1 (no) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9518606D0 (en) | 1995-09-12 | 1995-11-15 | Inst Of Psychiatry | Neural transplantation |
GB2306481A (en) | 1995-10-21 | 1997-05-07 | Univ Manchester | Pharmaceutical comprising a stimulator of activin and/or inhibin |
US7544511B2 (en) | 1996-09-25 | 2009-06-09 | Neuralstem Biopharmaceuticals Ltd. | Stable neural stem cell line methods |
JP2001504123A (ja) * | 1996-11-15 | 2001-03-27 | ニューロスフェレス ホールディングス リミテッド | Cns障害に対して保護するための成長因子を用いた予備治療 |
US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
US6093531A (en) | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
US6165783A (en) | 1997-10-24 | 2000-12-26 | Neuro Spheres Holdings Ltd. | Erythropoietin-mediated neurogenesis |
US6171610B1 (en) | 1998-04-24 | 2001-01-09 | University Of Massachusetts | Guided development and support of hydrogel-cell compositions |
US5958767A (en) * | 1998-08-14 | 1999-09-28 | The Children's Medical Center Corp. | Engraftable human neural stem cells |
SE9804064D0 (sv) | 1998-11-25 | 1998-11-25 | A & Science Invest Ab | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
US6238922B1 (en) * | 1999-02-26 | 2001-05-29 | Stemcells, Inc. | Use of collagenase in the preparation of neural stem cell cultures |
GB9907243D0 (en) | 1999-03-29 | 1999-05-26 | Reneuron Ltd | Therapy |
US6465215B1 (en) | 1999-12-14 | 2002-10-15 | Reneuron Limited | Identification of cells for transplantation |
ATE473751T1 (de) | 2000-02-11 | 2010-07-15 | Schepens Eye Res Inst | Isolierung und transplantation von retinalen stammzellen |
AU2001292350A1 (en) * | 2000-10-05 | 2002-04-15 | Takeda Chemical Industries Ltd. | Promoters for the proliferation and differentiation of stem cells and/or neuron precursor cells |
AR036401A1 (es) | 2001-09-14 | 2004-09-08 | Stem Cell Therapeutics Inc | Incremento de la cantidad de celulas madre neuronales inducido por prolactina. |
US7129034B2 (en) | 2001-10-25 | 2006-10-31 | Cedars-Sinai Medical Center | Differentiation of whole bone marrow |
CA2473503C (en) | 2002-01-14 | 2010-01-05 | The Board Of Trustees Of The University Of Illinois | Use of modified pyrimidine compounds to promote stem cell migration and proliferation |
CA2492542A1 (en) | 2002-07-30 | 2004-02-05 | Stem Cell Therapeutics Inc. | Oligodendrocyte production from multipotent neural stem cells |
KR100495532B1 (ko) * | 2002-09-18 | 2005-06-14 | 에프씨비파미셀 주식회사 | 간엽 간세포를 신경세포로 분화 및 증식시키는 방법 |
WO2004053071A2 (en) | 2002-12-09 | 2004-06-24 | Judith Kelleher-Andersson | Method for discovering neurogenic agents |
US8293488B2 (en) | 2002-12-09 | 2012-10-23 | Neuralstem, Inc. | Method for screening neurogenic agents |
ATE388223T1 (de) * | 2003-10-29 | 2008-03-15 | Fcb Pharmicell Co Ltd | Verfahren zur differenzierung einer mesenchym- stammzelle zu einer nervenzelle sowie die nervenzelle enthaltende pharmazeutische zusammensetzung gegen eine neurodegenerative krankheit |
JP4597538B2 (ja) * | 2004-02-03 | 2010-12-15 | 独立行政法人産業技術総合研究所 | 神経幹細胞増殖助剤及びこれを含んだ神経幹細胞用培地 |
US7846898B2 (en) | 2004-02-13 | 2010-12-07 | Stem Cell Therapeutics Corp. | Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis |
NZ551832A (en) * | 2004-06-09 | 2010-01-29 | Univ Edinburgh | Neural stem cells |
GB0505510D0 (en) * | 2004-06-09 | 2005-04-27 | Univ Edinburgh | Neural stem cells |
ES2294650T3 (es) | 2004-09-30 | 2008-04-01 | Reneuron Limited | Linea celular. |
KR101429284B1 (ko) | 2004-11-17 | 2014-08-11 | 뉴럴스템, 인크. | 신경퇴행성 증상의 치료를 위한 인간 신경 세포의 이식 |
US8287853B2 (en) | 2005-02-11 | 2012-10-16 | Agency For Science, Technology And Research | Methods of culturing mesenchymal stem cells |
US8178085B2 (en) | 2005-02-11 | 2012-05-15 | Agency For Science, Technology And Research | Methods of proliferating stem cells |
JP2009509943A (ja) | 2005-09-27 | 2009-03-12 | ステム セル セラピューティクス コーポレイション | プロラクチンにより制御される乏突起膠細胞前駆体細胞の増殖 |
CN1966080B (zh) * | 2005-11-17 | 2011-06-08 | 李凌松 | 一种治疗老年痴呆症、帕金森病的神经干细胞注射液 |
AU2007229301B2 (en) | 2006-03-17 | 2013-08-01 | Stem Cell Therapeutics Corp. | Continuous dosing regimens for neural stem cell proliferating agents and neural stem cell differentiating agents |
KR20080068352A (ko) * | 2007-01-19 | 2008-07-23 | 재단법인서울대학교산학협력재단 | 생체외 모델에 의한 신경재생물질 탐색 방법 |
JP2009278873A (ja) * | 2008-05-19 | 2009-12-03 | Japan Health Science Foundation | 培地および培養方法 |
WO2010075500A1 (en) | 2008-12-23 | 2010-07-01 | Stemcells California, Inc | Target populations of oligodendrocyte precursor cells and methods of making and using same |
KR102173873B1 (ko) | 2009-11-12 | 2020-11-04 | 브이셀 세라퓨틱스 인코포레이티드 | 포자를 닮은 세포들의 계군 및 그 용도 |
KR101765980B1 (ko) | 2010-07-28 | 2017-08-07 | 뉴럴스템, 인크. | 신경퇴행성 질환 및/또는 장애의 치료 및/또는 역전 방법 |
CN102839154A (zh) * | 2011-06-23 | 2012-12-26 | 上海安集协康生物技术有限公司 | 神经干细胞培养扩增方法及所用培养基 |
EP3492586B1 (en) | 2012-02-17 | 2024-04-17 | Schepens Eye Research Institute | Phenotype profile of human retinal progenitor cells |
EP3204021A4 (en) * | 2014-10-07 | 2018-03-07 | Nutech Medical, Inc. | Mesenchymal stem cell diagnostic testing |
MX2017005186A (es) | 2014-10-20 | 2017-07-26 | Neuralstem Inc | Celulas madre neurales estables que comprenden un polinucleótido exógeno que codifica un factor de crecimiento y métodos de uso de las mismas. |
CN104726407B (zh) * | 2014-11-24 | 2021-03-16 | 斯坦姆(天津)生物技术研究有限公司 | 一种利用器官培养以增加成年神经组织中神经干细胞收获率的方法 |
CN105647868B (zh) * | 2014-12-04 | 2020-03-31 | 中国科学院大连化学物理研究所 | 一种利用表面微结构激活星形神经胶质细胞的方法 |
JP6912789B2 (ja) * | 2016-03-16 | 2021-08-04 | 株式会社日本触媒 | 神経幹細胞の培養方法、およびニューロスフェロイドの形成方法 |
CN106497879A (zh) * | 2016-11-07 | 2017-03-15 | 广州赛莱拉干细胞科技股份有限公司 | 一种神经干细胞增殖和诱导其分化为多巴胺能神经元的培养基以及应用和增殖诱导方法 |
CN108070558B (zh) * | 2017-11-24 | 2022-01-28 | 吉林省拓华生物科技有限公司 | 一种临床级神经干细胞的制备方法 |
WO2020075534A1 (ja) * | 2018-10-11 | 2020-04-16 | 一丸ファルコス株式会社 | 神経幹細胞増殖用培地 |
CN112779209B (zh) * | 2019-11-08 | 2023-01-24 | 合肥中科普瑞昇生物医药科技有限公司 | 原代乳腺上皮细胞培养基、培养方法及其应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5100668A (en) * | 1988-06-14 | 1992-03-31 | Massachusetts Institute Of Technology | Controlled release systems containing heparin and growth factors |
DE69233061T3 (de) * | 1991-07-08 | 2008-07-10 | Neurospheres Holding Ltd., Calgary | Auf wachstumsfaktoren reagierende neurale vorläuferzellen, die in vitro vermehrt werden können. |
US5175103A (en) * | 1991-10-21 | 1992-12-29 | Trustees Of University Of Pennsylvania | Preparation of pure cultures of post-mitotic human neurons |
WO1994003199A1 (en) * | 1992-08-04 | 1994-02-17 | Regeneron Pharmaceuticals, Inc. | Method of enhancing differentiation and survival of neuronal precursor cells |
DE69332147T2 (de) * | 1992-10-16 | 2002-12-12 | Neurospheres Holding Ltd., Calgary | Remyelination unter verwendung von neuronalen stammzellen |
KR950704476A (ko) * | 1992-10-28 | 1995-11-20 | 브렌드 레이놀즈 | 생물학적 인자 및 신경 간세포(biological factors and neural stem cells) |
CA2155024C (en) * | 1993-01-29 | 1999-12-14 | Samuel Weiss | Genetic modification of neural stem cells |
AU697894B2 (en) * | 1993-11-09 | 1998-10-22 | Neurospheres Holdings Ltd | (In situ) modification and manipulation of stem cells of the central nervous system |
-
1995
- 1995-11-14 JP JP8515600A patent/JPH10509592A/ja not_active Ceased
- 1995-11-14 WO PCT/CA1995/000637 patent/WO1996015226A1/en not_active Application Discontinuation
- 1995-11-14 CN CN95196842A patent/CN1170435A/zh active Pending
- 1995-11-14 KR KR1019970703245A patent/KR970707272A/ko not_active Application Discontinuation
- 1995-11-14 EP EP95936393A patent/EP0792350A1/en not_active Withdrawn
- 1995-11-14 AU AU38367/95A patent/AU716811B2/en not_active Ceased
-
1997
- 1997-05-07 FI FI971956A patent/FI971956A/fi unknown
- 1997-05-12 NO NO972171A patent/NO972171L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI971956A0 (fi) | 1997-05-07 |
KR970707272A (ko) | 1997-12-01 |
WO1996015226A1 (en) | 1996-05-23 |
MX9703492A (es) | 1997-10-31 |
CN1170435A (zh) | 1998-01-14 |
AU716811B2 (en) | 2000-03-09 |
AU3836795A (en) | 1996-06-06 |
EP0792350A1 (en) | 1997-09-03 |
JPH10509592A (ja) | 1998-09-22 |
NO972171D0 (no) | 1997-05-12 |
NO972171L (no) | 1997-07-07 |
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