AU716811B2 - Regulation of neural stem cell proliferation - Google Patents
Regulation of neural stem cell proliferation Download PDFInfo
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- AU716811B2 AU716811B2 AU38367/95A AU3836795A AU716811B2 AU 716811 B2 AU716811 B2 AU 716811B2 AU 38367/95 A AU38367/95 A AU 38367/95A AU 3836795 A AU3836795 A AU 3836795A AU 716811 B2 AU716811 B2 AU 716811B2
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- C07K14/82—Translation products from oncogenes
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33873094A | 1994-11-14 | 1994-11-14 | |
| US08/338730 | 1994-11-14 | ||
| PCT/CA1995/000637 WO1996015226A1 (en) | 1994-11-14 | 1995-11-14 | Regulation of neural stem cell proliferation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU3836795A AU3836795A (en) | 1996-06-06 |
| AU716811B2 true AU716811B2 (en) | 2000-03-09 |
Family
ID=23325929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU38367/95A Ceased AU716811B2 (en) | 1994-11-14 | 1995-11-14 | Regulation of neural stem cell proliferation |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0792350A1 (no) |
| JP (1) | JPH10509592A (no) |
| KR (1) | KR970707272A (no) |
| CN (1) | CN1170435A (no) |
| AU (1) | AU716811B2 (no) |
| FI (1) | FI971956A (no) |
| NO (1) | NO972171L (no) |
| WO (1) | WO1996015226A1 (no) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9518606D0 (en) * | 1995-09-12 | 1995-11-15 | Inst Of Psychiatry | Neural transplantation |
| GB2306481A (en) | 1995-10-21 | 1997-05-07 | Univ Manchester | Pharmaceutical comprising a stimulator of activin and/or inhibin |
| US7544511B2 (en) | 1996-09-25 | 2009-06-09 | Neuralstem Biopharmaceuticals Ltd. | Stable neural stem cell line methods |
| CA2266659A1 (en) * | 1996-11-15 | 1998-05-28 | Paule Poulin | Pretreatment with growth factors to protect against cns damage |
| US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
| US6093531A (en) * | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
| US6165783A (en) | 1997-10-24 | 2000-12-26 | Neuro Spheres Holdings Ltd. | Erythropoietin-mediated neurogenesis |
| US6171610B1 (en) | 1998-04-24 | 2001-01-09 | University Of Massachusetts | Guided development and support of hydrogel-cell compositions |
| US5958767A (en) * | 1998-08-14 | 1999-09-28 | The Children's Medical Center Corp. | Engraftable human neural stem cells |
| SE9804064D0 (sv) | 1998-11-25 | 1998-11-25 | A & Science Invest Ab | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
| US6238922B1 (en) * | 1999-02-26 | 2001-05-29 | Stemcells, Inc. | Use of collagenase in the preparation of neural stem cell cultures |
| GB9907243D0 (en) | 1999-03-29 | 1999-05-26 | Reneuron Ltd | Therapy |
| US6465215B1 (en) | 1999-12-14 | 2002-10-15 | Reneuron Limited | Identification of cells for transplantation |
| ATE473751T1 (de) | 2000-02-11 | 2010-07-15 | Schepens Eye Res Inst | Isolierung und transplantation von retinalen stammzellen |
| US20040034049A1 (en) * | 2000-10-05 | 2004-02-19 | Shigenori Okawa | Promoters for the proliferation and differentiation of stem cells and/or neuron precursor cells |
| CA2460184A1 (en) | 2001-09-14 | 2003-03-27 | Stem Cell Therapeutics Inc. | Prolactin induced increase in neural stem cell numbers and therapeutical use thereof |
| US7129034B2 (en) | 2001-10-25 | 2006-10-31 | Cedars-Sinai Medical Center | Differentiation of whole bone marrow |
| AU2003216058A1 (en) | 2002-01-14 | 2003-07-30 | The Board Of Trustees Of The University Of Illinois | Mammalian neural stem cells, compositions and uses thereof |
| AU2003250697B2 (en) | 2002-07-30 | 2008-05-01 | Stem Cell Therapeutics Inc. | Oligodendrocyte production from multipotent neural stem cells |
| KR100495532B1 (ko) * | 2002-09-18 | 2005-06-14 | 에프씨비파미셀 주식회사 | 간엽 간세포를 신경세포로 분화 및 증식시키는 방법 |
| US8293488B2 (en) | 2002-12-09 | 2012-10-23 | Neuralstem, Inc. | Method for screening neurogenic agents |
| US20040185429A1 (en) | 2002-12-09 | 2004-09-23 | Judith Kelleher-Andersson | Method for discovering neurogenic agents |
| WO2005040362A1 (en) * | 2003-10-29 | 2005-05-06 | Fcb Pharmicell Co., Ltd | Method for differentiating mesenchymal stem cell into neural cell and pharmaceutical composition containing the neural cell for neurodegenerative disease |
| JP4597538B2 (ja) * | 2004-02-03 | 2010-12-15 | 独立行政法人産業技術総合研究所 | 神経幹細胞増殖助剤及びこれを含んだ神経幹細胞用培地 |
| US7846898B2 (en) | 2004-02-13 | 2010-12-07 | Stem Cell Therapeutics Corp. | Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis |
| JP2008501356A (ja) | 2004-06-09 | 2008-01-24 | ザ・ユニバーシティ・コート・オブ・ザ・ユニバーシティ・オブ・エディンバラ | 神経幹細胞 |
| GB0505510D0 (en) * | 2004-06-09 | 2005-04-27 | Univ Edinburgh | Neural stem cells |
| ES2294650T3 (es) | 2004-09-30 | 2008-04-01 | Reneuron Limited | Linea celular. |
| RU2434636C2 (ru) | 2004-11-17 | 2011-11-27 | Ньюралстем, Инк. | Трансплантация нервных клеток для лечения нейродегенеративных состояний |
| US8287853B2 (en) | 2005-02-11 | 2012-10-16 | Agency For Science, Technology And Research | Methods of culturing mesenchymal stem cells |
| CN101155913B (zh) * | 2005-02-11 | 2011-07-06 | 新加坡科技研究局 | 增殖干细胞的方法 |
| WO2007036033A1 (en) | 2005-09-27 | 2007-04-05 | Stem Cell Therapeutics Corp. | Oligodendrocyte precursor cell proliferation regulated by prolactin |
| CN1966080B (zh) * | 2005-11-17 | 2011-06-08 | 李凌松 | 一种治疗老年痴呆症、帕金森病的神经干细胞注射液 |
| JP2009530234A (ja) | 2006-03-17 | 2009-08-27 | ステム セル セラピューティクス コーポレイション | 神経変性疾患の治療のためのｌｈまたはｈｃｇ、およびｅｐｏについての投与レジメン |
| KR20080068352A (ko) * | 2007-01-19 | 2008-07-23 | 재단법인서울대학교산학협력재단 | 생체외 모델에 의한 신경재생물질 탐색 방법 |
| JP2009278873A (ja) * | 2008-05-19 | 2009-12-03 | Japan Health Science Foundation | 培地および培養方法 |
| CN102325878A (zh) | 2008-12-23 | 2012-01-18 | 斯特姆塞尔思加利福尼亚有限公司 | 少突胶质前体细胞的靶向细胞群及制备与使用方法 |
| WO2011060135A1 (en) | 2009-11-12 | 2011-05-19 | Vbi Technologies, Llc | Subpopulations of spore-like cells and uses thereof |
| SG187226A1 (en) | 2010-07-28 | 2013-03-28 | Neuralstem Inc | Methods for treating and/or reversing neurodegenerative diseases and/or disorders |
| CN102839154A (zh) * | 2011-06-23 | 2012-12-26 | 上海安集协康生物技术有限公司 | 神经干细胞培养扩增方法及所用培养基 |
| BR112014019328A8 (pt) | 2012-02-17 | 2017-07-11 | The Schepens Eye Res Institute | Perfil de fenótipo de células progenitoras retinais humanas |
| US20170248581A1 (en) * | 2014-10-07 | 2017-08-31 | NuTech Medical, Inc. | Mesenchymal Stem Cell Diagnostic Testing |
| KR20190060016A (ko) | 2014-10-20 | 2019-05-31 | 뉴럴스템, 인크. | 성장 인자를 코딩하는 외인성 폴리뉴클레오티드를 포함하는 안정한 신경 줄기세포 및 그의 사용 방법 |
| CN104726407B (zh) * | 2014-11-24 | 2021-03-16 | 斯坦姆（天津）生物技术研究有限公司 | 一种利用器官培养以增加成年神经组织中神经干细胞收获率的方法 |
| CN105647868B (zh) * | 2014-12-04 | 2020-03-31 | 中国科学院大连化学物理研究所 | 一种利用表面微结构激活星形神经胶质细胞的方法 |
| JP6912789B2 (ja) * | 2016-03-16 | 2021-08-04 | 株式会社日本触媒 | 神経幹細胞の培養方法、およびニューロスフェロイドの形成方法 |
| CN106497879A (zh) * | 2016-11-07 | 2017-03-15 | 广州赛莱拉干细胞科技股份有限公司 | 一种神经干细胞增殖和诱导其分化为多巴胺能神经元的培养基以及应用和增殖诱导方法 |
| CN108070558B (zh) * | 2017-11-24 | 2022-01-28 | 吉林省拓华生物科技有限公司 | 一种临床级神经干细胞的制备方法 |
| WO2020075534A1 (ja) * | 2018-10-11 | 2020-04-16 | 一丸ファルコス株式会社 | 神経幹細胞増殖用培地 |
| CN112779209B (zh) * | 2019-11-08 | 2023-01-24 | 合肥中科普瑞昇生物医药科技有限公司 | 原代乳腺上皮细胞培养基、培养方法及其应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993001275A1 (en) * | 1991-07-08 | 1993-01-21 | Neurospheres Ltd. | NOVEL GROWTH FACTOR-RESPONSIVE PROGENITOR CELLS WHICH CAN BE PROLIFERATED $i(IN VITRO) |
| WO1994003199A1 (en) * | 1992-08-04 | 1994-02-17 | Regeneron Pharmaceuticals, Inc. | Method of enhancing differentiation and survival of neuronal precursor cells |
| AU8056194A (en) * | 1993-11-09 | 1995-05-29 | Neurospheres Holdings Ltd | (in situ) modification and manipulation of stem cells of the central nervous system |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5100668A (en) * | 1988-06-14 | 1992-03-31 | Massachusetts Institute Of Technology | Controlled release systems containing heparin and growth factors |
| US5175103A (en) * | 1991-10-21 | 1992-12-29 | Trustees Of University Of Pennsylvania | Preparation of pure cultures of post-mitotic human neurons |
| DE69332147T2 (de) * | 1992-10-16 | 2002-12-12 | Neurospheres Holding Ltd., Calgary | Remyelination unter verwendung von neuronalen stammzellen |
| AU5367694A (en) * | 1992-10-28 | 1994-05-24 | Neurospheres Holdings Ltd | Biological factors and neural stem cells |
| ES2218524T3 (es) * | 1993-01-29 | 2004-11-16 | Neurospheres Holdings Ltd. | Modificacion genetica de celulas primordiales neurales. |
-
1995
- 1995-11-14 CN CN95196842A patent/CN1170435A/zh active Pending
- 1995-11-14 JP JP8515600A patent/JPH10509592A/ja not_active Ceased
- 1995-11-14 WO PCT/CA1995/000637 patent/WO1996015226A1/en not_active Application Discontinuation
- 1995-11-14 EP EP95936393A patent/EP0792350A1/en not_active Withdrawn
- 1995-11-14 AU AU38367/95A patent/AU716811B2/en not_active Ceased
- 1995-11-14 KR KR1019970703245A patent/KR970707272A/ko not_active Application Discontinuation
-
1997
- 1997-05-07 FI FI971956A patent/FI971956A/fi unknown
- 1997-05-12 NO NO972171A patent/NO972171L/no not_active Application Discontinuation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993001275A1 (en) * | 1991-07-08 | 1993-01-21 | Neurospheres Ltd. | NOVEL GROWTH FACTOR-RESPONSIVE PROGENITOR CELLS WHICH CAN BE PROLIFERATED $i(IN VITRO) |
| WO1994003199A1 (en) * | 1992-08-04 | 1994-02-17 | Regeneron Pharmaceuticals, Inc. | Method of enhancing differentiation and survival of neuronal precursor cells |
| AU8056194A (en) * | 1993-11-09 | 1995-05-29 | Neurospheres Holdings Ltd | (in situ) modification and manipulation of stem cells of the central nervous system |
Also Published As
| Publication number | Publication date |
|---|---|
| MX9703492A (es) | 1997-10-31 |
| AU3836795A (en) | 1996-06-06 |
| FI971956A (fi) | 1997-07-04 |
| FI971956A0 (fi) | 1997-05-07 |
| KR970707272A (ko) | 1997-12-01 |
| NO972171D0 (no) | 1997-05-12 |
| CN1170435A (zh) | 1998-01-14 |
| WO1996015226A1 (en) | 1996-05-23 |
| JPH10509592A (ja) | 1998-09-22 |
| EP0792350A1 (en) | 1997-09-03 |
| NO972171L (no) | 1997-07-07 |
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