FI962702A0 - Medel för effektivering av estradiolens penetrering - Google Patents

Medel för effektivering av estradiolens penetrering

Info

Publication number
FI962702A0
FI962702A0 FI962702A FI962702A FI962702A0 FI 962702 A0 FI962702 A0 FI 962702A0 FI 962702 A FI962702 A FI 962702A FI 962702 A FI962702 A FI 962702A FI 962702 A0 FI962702 A0 FI 962702A0
Authority
FI
Finland
Prior art keywords
pct
estradiol
sec
active substance
penetration enhancing
Prior art date
Application number
FI962702A
Other languages
English (en)
Finnish (fi)
Other versions
FI118719B (sv
FI962702A (sv
Inventor
Reinhold Meconi
Frank Seibertz
Original Assignee
Lts Lohmann Therapie Systemi G
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmann Therapie Systemi G filed Critical Lts Lohmann Therapie Systemi G
Publication of FI962702A0 publication Critical patent/FI962702A0/sv
Publication of FI962702A publication Critical patent/FI962702A/sv
Application granted granted Critical
Publication of FI118719B publication Critical patent/FI118719B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
FI962702A 1994-01-13 1996-06-28 Faktor för förstärkande av estradiols penetrering FI118719B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4400770A DE4400770C1 (de) 1994-01-13 1994-01-13 Wirkstoffhaltiges Pflaster zur Abgabe von Estradiol mit mindestens einem Penetrationsverstärker, Verfahren zu seiner Herstellung und seine Verwendung
DE4400770 1994-01-13
PCT/EP1995/000032 WO1995019162A1 (de) 1994-01-13 1995-01-05 Estradiol-penetrationsverstärker zur transdermalen verabreichung
EP9500032 1995-01-05

Publications (3)

Publication Number Publication Date
FI962702A0 true FI962702A0 (sv) 1996-06-28
FI962702A FI962702A (sv) 1996-08-27
FI118719B FI118719B (sv) 2008-02-29

Family

ID=6507821

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962702A FI118719B (sv) 1994-01-13 1996-06-28 Faktor för förstärkande av estradiols penetrering

Country Status (22)

Country Link
US (1) US6090404A (sv)
EP (1) EP0739199B1 (sv)
JP (1) JP3980633B2 (sv)
KR (1) KR100374087B1 (sv)
AT (1) ATE215363T1 (sv)
AU (1) AU707963B2 (sv)
CZ (1) CZ287330B6 (sv)
DE (2) DE4400770C1 (sv)
DK (1) DK0739199T3 (sv)
ES (1) ES2174922T3 (sv)
FI (1) FI118719B (sv)
HU (1) HU222499B1 (sv)
IL (1) IL112145A (sv)
MY (1) MY113680A (sv)
NO (1) NO962933L (sv)
NZ (1) NZ278593A (sv)
PL (1) PL184875B1 (sv)
PT (1) PT739199E (sv)
SI (1) SI0739199T1 (sv)
SK (1) SK280530B6 (sv)
WO (1) WO1995019162A1 (sv)
ZA (1) ZA95226B (sv)

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AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
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GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
EP1171091A1 (de) * 1999-04-16 2002-01-16 Jenapharm GmbH & Co. KG Pharmazeutische oder kosmetische zusammensetzungen zur lokalen, intradermalen applikation von estrogenen
US6974588B1 (en) * 1999-12-07 2005-12-13 Elan Pharma International Limited Transdermal patch for delivering volatile liquid drugs
GB0103046D0 (en) * 2001-02-07 2001-03-21 Novartis Ag Organic Compounds
EP1596756A4 (en) * 2003-01-23 2009-11-11 Supernus Pharmaceuticals Inc MEANS TO INCREASE ABSORPTION
JP5254616B2 (ja) * 2004-09-13 2013-08-07 クロノ セラピューティクス、インコーポレイテッド 生物学的同調性（ｂｉｏｓｙｎｃｈｒｏｎｏｕｓ）経皮的薬物送達
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US20070042026A1 (en) * 2005-03-17 2007-02-22 Wille John J Prophylactic and therapeutic treatment of topical and transdermal drug-induced skin reactions
US8372040B2 (en) 2005-05-24 2013-02-12 Chrono Therapeutics, Inc. Portable drug delivery device including a detachable and replaceable administration or dosing element
JP5162862B2 (ja) * 2005-09-16 2013-03-13 株式会社リコー 感熱性粘着剤及び感熱性粘着材料
US20080200890A1 (en) * 2006-12-11 2008-08-21 3M Innovative Properties Company Antimicrobial disposable absorbent articles
US9555167B2 (en) * 2006-12-11 2017-01-31 3M Innovative Properties Company Biocompatible antimicrobial compositions
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
ES2885523T3 (es) 2011-11-23 2021-12-14 Therapeuticsmd Inc Formulaciones y terapias de reposición hormonal de combinación naturales
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CA2974324A1 (en) 2015-01-28 2016-08-04 Zita S. Netzel Drug delivery methods and systems
WO2016145373A1 (en) 2015-03-12 2016-09-15 Chrono Therapeutics Inc. Craving input and support system
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US20190307664A1 (en) * 2016-06-15 2019-10-10 Conopco, Inc., D/B/A Unilever Method and cosmetic composition for enhanced transdermal delivery of alkyl substituted resorcinol
AU2018205529B2 (en) 2017-01-06 2023-08-10 Morningside Venture Investments Limited Transdermal drug delivery devices and methods
JP7420797B2 (ja) 2018-05-29 2024-01-23 モーニングサイド ベンチャー インベストメンツ リミテッド 薬剤送達の方法及びシステム
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
CN115010949B (zh) * 2022-07-12 2024-02-13 华熙生物科技股份有限公司 促渗物、护肤品组合物以及化妆品

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Also Published As

Publication number Publication date
HU9601872D0 (en) 1996-09-30
DK0739199T3 (da) 2002-07-29
NZ278593A (en) 1997-12-19
PL315527A1 (en) 1996-11-12
DE4400770C1 (de) 1995-02-02
MY113680A (en) 2002-04-30
ZA95226B (en) 1996-02-07
CZ205396A3 (en) 1996-10-16
ES2174922T3 (es) 2002-11-16
JPH09511229A (ja) 1997-11-11
HU222499B1 (hu) 2003-07-28
CZ287330B6 (en) 2000-10-11
US6090404A (en) 2000-07-18
IL112145A0 (en) 1995-03-15
SI0739199T1 (en) 2002-10-31
NO962933L (no) 1996-09-12
WO1995019162A1 (de) 1995-07-20
NO962933D0 (no) 1996-07-12
IL112145A (en) 2000-10-31
SK91596A3 (en) 1997-03-05
SK280530B6 (sk) 2000-03-13
PT739199E (pt) 2002-09-30
PL184875B1 (pl) 2003-01-31
JP3980633B2 (ja) 2007-09-26
EP0739199B1 (de) 2002-04-03
AU1455295A (en) 1995-08-01
KR970700021A (ko) 1997-01-08
FI118719B (sv) 2008-02-29
FI962702A (sv) 1996-08-27
AU707963B2 (en) 1999-07-22
EP0739199A1 (de) 1996-10-30
ATE215363T1 (de) 2002-04-15
DE59510142D1 (de) 2002-05-08
HUT74455A (en) 1996-12-30
KR100374087B1 (ko) 2003-04-23

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