FI962022A0 - 5,6-dihydropyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina - Google Patents
5,6-dihydropyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineinaInfo
- Publication number
- FI962022A0 FI962022A0 FI962022A FI962022A FI962022A0 FI 962022 A0 FI962022 A0 FI 962022A0 FI 962022 A FI962022 A FI 962022A FI 962022 A FI962022 A FI 962022A FI 962022 A0 FI962022 A0 FI 962022A0
- Authority
- FI
- Finland
- Prior art keywords
- antivirals
- dihydropyrone derivatives
- protease inhibitors
- dihydropyrone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15544393A | 1993-11-19 | 1993-11-19 | |
| US08/319,820 US5840751A (en) | 1993-11-19 | 1994-10-12 | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents |
| PCT/US1994/012269 WO1995014012A1 (en) | 1993-11-19 | 1994-10-26 | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI962022A0 true FI962022A0 (fi) | 1996-05-13 |
| FI962022A FI962022A (fi) | 1996-07-12 |
Family
ID=26852338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI962022A FI962022A (fi) | 1993-11-19 | 1996-05-13 | 5,6-dihydropyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0729464A1 (fi) |
| JP (1) | JP3684426B2 (fi) |
| AT (1) | ATE263761T1 (fi) |
| AU (1) | AU689158B2 (fi) |
| CA (1) | CA2176043A1 (fi) |
| DE (1) | DE69433705T2 (fi) |
| DK (1) | DK1142887T3 (fi) |
| ES (1) | ES2219457T3 (fi) |
| FI (1) | FI962022A (fi) |
| HR (1) | HRP940935B1 (fi) |
| HU (1) | HUT77668A (fi) |
| IL (1) | IL111674A0 (fi) |
| NO (1) | NO316172B1 (fi) |
| NZ (1) | NZ275961A (fi) |
| PT (1) | PT1142887E (fi) |
| RU (1) | RU2140917C1 (fi) |
| SI (1) | SI1142887T1 (fi) |
| WO (1) | WO1995014012A1 (fi) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69632422T2 (de) * | 1995-08-11 | 2005-05-19 | Zenon Environmental Inc., Oakville | Verfahren zum Einbetten von Hohlfaser-Membranen |
| US5834506A (en) * | 1996-11-01 | 1998-11-10 | Warner-Lambert Company | Dihydropyrones with improved antiviral activity |
| KR100569771B1 (ko) * | 1997-09-11 | 2006-04-11 | 파마시아 앤드 업존 캄파니 엘엘씨 | 프로테아제 억제제로서 유용한 4-히드록시-2-옥소-피란유도체의 제조 방법 |
| AU773567B2 (en) * | 1998-09-11 | 2004-05-27 | Warner-Lambert Company | HIV protease inhibitors |
| US6288235B1 (en) | 1999-04-14 | 2001-09-11 | Ortho-Mcneil Pharmaceutical, Inc. | Methods for the synthesis of highly substituted 2,4-dioxopiperidine libraries |
| DE10030094A1 (de) * | 2000-06-19 | 2001-12-20 | Bayer Ag | Phenylsubstituierte 5,6-Dihydro-pyron-Derivate |
| US6710058B2 (en) | 2000-11-06 | 2004-03-23 | Bristol-Myers Squibb Pharma Company | Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors |
| DE10108471C1 (de) | 2001-02-22 | 2002-11-21 | Boehringer Ingelheim Pharma | Kontinuierliches Verfahren zur Herstellung von 5,6-Dihydro-4-hydroxy-2-pyronen |
| US6500963B2 (en) | 2001-02-22 | 2002-12-31 | Boehringer Ingelheim Pharma Kg | Process for preparing optically active dihydropyrones |
| US7141681B2 (en) | 2001-02-22 | 2006-11-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Continuous process for preparing dihydropyrones |
| DE10108470A1 (de) * | 2001-02-22 | 2002-09-05 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung optisch aktiver Dihydropyrone |
| TW200307667A (en) | 2002-05-06 | 2003-12-16 | Bristol Myers Squibb Co | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors |
| DOP2003000641A (es) | 2002-05-10 | 2003-11-15 | Pfizer | Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan |
| US7148226B2 (en) | 2003-02-21 | 2006-12-12 | Agouron Pharmaceuticals, Inc. | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same |
| ES2361845T3 (es) | 2004-08-18 | 2011-06-22 | Pfizer, Inc. | Inhibidores de arn polimerasa dependiente del arn del virus de la hepatitis c y composiciones y tratamientos que utilizan los mismos. |
| DE102005059469A1 (de) | 2005-12-13 | 2007-06-14 | Bayer Cropscience Ag | Insektizide Zusammensetzungen mit verbesserter Wirkung |
| DE102006007882A1 (de) | 2006-02-21 | 2007-08-30 | Bayer Cropscience Ag | Cycloalkyl-phenylsubstituierte cyclische Ketoenole |
| NZ573706A (en) * | 2006-06-16 | 2011-09-30 | Pharma Mar Sa | Antitumoral dihydropyran-2-one compounds |
| CN103641709B (zh) | 2009-03-11 | 2017-08-25 | 拜耳知识产权有限责任公司 | 被卤代烷基亚甲基氧基苯基取代的酮烯醇 |
| DE102010008644A1 (de) | 2010-02-15 | 2011-08-18 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Zyklische Ketoenole zur Therapie |
| RU2461555C1 (ru) * | 2011-07-07 | 2012-09-20 | Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" | Способ получения 5-арил-3-фенил-2-оксаспиро[5,6]додец-3-ен-1-онов, проявляющих анальгетическую активность |
| DK2806741T3 (da) | 2012-01-26 | 2020-05-18 | Bayer Ip Gmbh | Phenylsubstituerede ketoenoler til bekæmpelse af fiskeparasitter |
| JP6205427B2 (ja) | 2012-11-28 | 2017-09-27 | 住友化学株式会社 | ジヒドロピロン化合物及びそれを含有する除草剤 |
| SE539512C2 (sv) * | 2015-12-02 | 2017-10-03 | Ultupharma Ab | Compounds and methods of treating bacterial infections |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3818046A (en) * | 1972-12-18 | 1974-06-18 | Dow Chemical Co | Sulfur-containing hydroxy pyrones and alkali metal salts thereof |
| ZA938019B (en) * | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
-
1994
- 1994-10-26 CA CA002176043A patent/CA2176043A1/en not_active Abandoned
- 1994-10-26 SI SI9430463T patent/SI1142887T1/xx unknown
- 1994-10-26 NZ NZ275961A patent/NZ275961A/en unknown
- 1994-10-26 PT PT01114943T patent/PT1142887E/pt unknown
- 1994-10-26 WO PCT/US1994/012269 patent/WO1995014012A1/en not_active Application Discontinuation
- 1994-10-26 ES ES01114943T patent/ES2219457T3/es not_active Expired - Lifetime
- 1994-10-26 HU HU9601348A patent/HUT77668A/hu not_active Application Discontinuation
- 1994-10-26 EP EP95900429A patent/EP0729464A1/en not_active Withdrawn
- 1994-10-26 RU RU96113098/04A patent/RU2140917C1/ru not_active IP Right Cessation
- 1994-10-26 AT AT01114943T patent/ATE263761T1/de not_active IP Right Cessation
- 1994-10-26 AU AU81256/94A patent/AU689158B2/en not_active Ceased
- 1994-10-26 JP JP51445895A patent/JP3684426B2/ja not_active Expired - Fee Related
- 1994-10-26 DE DE69433705T patent/DE69433705T2/de not_active Expired - Fee Related
- 1994-10-26 DK DK01114943T patent/DK1142887T3/da active
- 1994-11-17 IL IL11167494A patent/IL111674A0/xx unknown
- 1994-11-17 HR HR940935A patent/HRP940935B1/xx not_active IP Right Cessation
-
1996
- 1996-05-13 FI FI962022A patent/FI962022A/fi unknown
- 1996-05-15 NO NO19962017A patent/NO316172B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU689158B2 (en) | 1998-03-26 |
| ATE263761T1 (de) | 2004-04-15 |
| PT1142887E (pt) | 2004-08-31 |
| DE69433705T2 (de) | 2005-03-10 |
| DK1142887T3 (da) | 2004-06-21 |
| SI1142887T1 (en) | 2004-08-31 |
| DE69433705D1 (de) | 2004-05-13 |
| HU9601348D0 (en) | 1996-07-29 |
| NZ275961A (en) | 2001-11-30 |
| EP0729464A1 (en) | 1996-09-04 |
| JPH09505294A (ja) | 1997-05-27 |
| RU2140917C1 (ru) | 1999-11-10 |
| CA2176043A1 (en) | 1995-05-26 |
| FI962022A (fi) | 1996-07-12 |
| JP3684426B2 (ja) | 2005-08-17 |
| NO962017D0 (no) | 1996-05-15 |
| AU8125694A (en) | 1995-06-06 |
| IL111674A0 (en) | 1995-01-24 |
| HRP940935A2 (en) | 1997-04-30 |
| WO1995014012A1 (en) | 1995-05-26 |
| ES2219457T3 (es) | 2004-12-01 |
| HUT77668A (hu) | 1998-07-28 |
| HRP940935B1 (en) | 2004-08-31 |
| NO316172B1 (no) | 2003-12-22 |
| NO962017L (no) | 1996-07-08 |
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| MY138860A (en) | Hiv protease inhibitors. | |
| DK0729463T3 (da) | 5,6-Dihydropyronderivater som proteaseinhibitorer og antivirale midler | |
| MD960171A (ro) | Derivaţi ai pironei folosiţi ca inhibitori ai proteazei şi agenţi antivirali | |
| FI962020A0 (fi) | Pyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina | |
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