FI953747A0 - Steroideja vaihdevuosivaivojen hoitoon - Google Patents

Steroideja vaihdevuosivaivojen hoitoon

Info

Publication number
FI953747A0
FI953747A0 FI953747A FI953747A FI953747A0 FI 953747 A0 FI953747 A0 FI 953747A0 FI 953747 A FI953747 A FI 953747A FI 953747 A FI953747 A FI 953747A FI 953747 A0 FI953747 A0 FI 953747A0
Authority
FI
Finland
Prior art keywords
steroids
treatment
menopause disorders
menopause
disorders
Prior art date
Application number
FI953747A
Other languages
English (en)
Swedish (sv)
Other versions
FI953747A (fi
FI114101B (fi
Inventor
Hubert Jan Jozef Loozen
Lodewijk Pieter Cornelis Schot
De Werfpieters Jane Margre Van
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of FI953747A0 publication Critical patent/FI953747A0/fi
Publication of FI953747A publication Critical patent/FI953747A/fi
Application granted granted Critical
Publication of FI114101B publication Critical patent/FI114101B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C07J33/007—Cyclic thioketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI953747A 1993-02-08 1995-08-07 Menetelmä vaihdevuosivaivojen hoitoon käyttökelpoisten steroidien valmistamiseksi FI114101B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP93200332 1993-02-08
EP93200332 1993-02-08
PCT/EP1994/000348 WO1994018224A1 (en) 1993-02-08 1994-02-04 Steroids for treating menopausal complaints
EP9400348 1994-02-04

Publications (3)

Publication Number Publication Date
FI953747A0 true FI953747A0 (fi) 1995-08-07
FI953747A FI953747A (fi) 1995-09-12
FI114101B FI114101B (fi) 2004-08-13

Family

ID=8213615

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953747A FI114101B (fi) 1993-02-08 1995-08-07 Menetelmä vaihdevuosivaivojen hoitoon käyttökelpoisten steroidien valmistamiseksi

Country Status (15)

Country Link
EP (1) EP0682672A1 (fi)
JP (1) JPH08506116A (fi)
KR (1) KR100364113B1 (fi)
CN (1) CN1046735C (fi)
AU (1) AU4675897A (fi)
BR (1) BR9405825A (fi)
CA (1) CA2155532A1 (fi)
FI (1) FI114101B (fi)
HU (2) HU220615B1 (fi)
NO (1) NO308583B1 (fi)
NZ (1) NZ261581A (fi)
PL (1) PL182901B1 (fi)
RU (1) RU2172740C2 (fi)
WO (1) WO1994018224A1 (fi)
ZA (1) ZA94715B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL123195A (en) * 1997-02-21 2002-11-10 Akzo Nobel Nv Steroid compounds with anti-pregnancy activity and against bone thinning, preparation and pharmaceutical preparations containing them
BR9908605A (pt) * 1998-03-09 2001-04-24 Akzo Nobel Nv Kit anticoncepcional, uso de um composto esteróide, e, processo de contracepção
EP1224204B1 (en) * 1999-09-06 2005-05-18 Akzo Nobel N.V. Non-aromatic estrogenic steroids with a hydrocarbon substituent in position 11
CN1220696C (zh) 2000-07-28 2005-09-28 阿克佐诺贝尔公司 16α－甲基或乙基取代的雌激素
UA89964C2 (ru) 2004-09-08 2010-03-25 Н.В. Органон 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
EP3423464B1 (en) * 2016-03-03 2021-05-26 Crystal Pharma, S.A.U. Process and new intermediates for the preparation of 11-methylene steroids

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3325520A (en) * 1965-12-08 1967-06-13 Searle & Co (optionally 17-hydrocarbon-substituted) 11, 13beta-dialkylgon-4-en-3-ones and esters corresponding
US3465010A (en) * 1966-11-22 1969-09-02 Searle & Co 17 - (unsaturated hydrocarbon - substituted) 11,13beta - dialkylgon -4 - ene - 3,17beta-diols and esters thereof
FI54128C (fi) * 1972-12-09 1978-10-10 Akzo Nv Foerfarande foer framstaellning av nya 11,11-alkylidensteroider ur oestran- och 19-norpregnanserien med foerbaettrad hormonell verkan
NL175063C (nl) * 1972-12-09 1984-09-17 Akzo Nv Werkwijze ter bereiding van 11,11-alkylideensteroiden, werkwijze ter bereiding van farmaceutische preparaten en gevormde farmaceutische preparaten.
NL7317358A (nl) * 1973-12-19 1975-06-23 Akzo Nv Nieuwe 11(beta)-alkylsteroiden van de oestraanreeks.
NL7701384A (nl) * 1977-02-10 1978-08-14 Akzo Nv Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks.
AU532512B2 (en) * 1979-09-07 1983-10-06 Upjohn and Horton Anti-allergenic compounds for bone mineral resorption
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
AU572589B2 (en) * 1983-12-14 1988-05-12 Upjohn Company, The 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
NL8502571A (nl) * 1985-09-20 1987-04-16 Akzo Nv Steroiden met immunomodulerende eigenschappen.
DE3702383A1 (de) * 1987-01-23 1988-08-04 Schering Ag 11ss-alkinylestrene und -estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
HUT52382A (en) * 1988-03-14 1990-07-28 Sandoz Ag Process for producing pharmaceutical compositions comprising as active ingredient unsubstituted progestin in 19-position and estrogen in the given case
ATE99939T1 (de) * 1990-06-14 1994-01-15 Henning Berlin Gmbh Fluessig befuellte steckkapselpraeparate.
AU8166191A (en) * 1990-08-10 1992-02-13 Ortho Pharmaceutical Corporation Method for treatment of bone wasting diseases

Also Published As

Publication number Publication date
BR9405825A (pt) 1995-12-05
AU682170B2 (en) 1997-09-25
PL310125A1 (en) 1995-11-27
FI953747A (fi) 1995-09-12
FI114101B (fi) 2004-08-13
ZA94715B (en) 1994-10-24
NO953089D0 (no) 1995-08-07
AU4675897A (en) 1998-02-19
PL182901B1 (pl) 2002-03-29
CN1046735C (zh) 1999-11-24
AU6039494A (en) 1994-08-29
JPH08506116A (ja) 1996-07-02
HU0102320D0 (en) 2001-08-28
HUT72971A (en) 1996-06-28
WO1994018224A1 (en) 1994-08-18
NO308583B1 (no) 2000-10-02
NZ261581A (en) 1997-06-24
EP0682672A1 (en) 1995-11-22
HU220615B1 (hu) 2002-03-28
CN1117735A (zh) 1996-02-28
KR100364113B1 (ko) 2003-04-08
CA2155532A1 (en) 1994-08-18
HU9501940D0 (en) 1995-09-28
RU2172740C2 (ru) 2001-08-27
NO953089L (no) 1995-10-06

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Legal Events

Date Code Title Description
MA Patent expired