ZA94715B - Steroids for treating menopausal complaints - Google Patents

Steroids for treating menopausal complaints

Info

Publication number
ZA94715B
ZA94715B ZA94715A ZA94715A ZA94715B ZA 94715 B ZA94715 B ZA 94715B ZA 94715 A ZA94715 A ZA 94715A ZA 94715 A ZA94715 A ZA 94715A ZA 94715 B ZA94715 B ZA 94715B
Authority
ZA
South Africa
Prior art keywords
steroids
treating menopausal
menopausal complaints
complaints
treating
Prior art date
Application number
ZA94715A
Inventor
Hubert Jan Jozef Loozen
Lodewijk Pieter Cornelis Schot
Van De J M L Werf-Pieters
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ZA94715B publication Critical patent/ZA94715B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C07J33/007—Cyclic thioketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA94715A 1993-02-08 1994-02-02 Steroids for treating menopausal complaints ZA94715B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93200332 1993-02-08

Publications (1)

Publication Number Publication Date
ZA94715B true ZA94715B (en) 1994-10-24

Family

ID=8213615

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA94715A ZA94715B (en) 1993-02-08 1994-02-02 Steroids for treating menopausal complaints

Country Status (15)

Country Link
EP (1) EP0682672A1 (en)
JP (1) JPH08506116A (en)
KR (1) KR100364113B1 (en)
CN (1) CN1046735C (en)
AU (1) AU4675897A (en)
BR (1) BR9405825A (en)
CA (1) CA2155532A1 (en)
FI (1) FI114101B (en)
HU (2) HU0102320D0 (en)
NO (1) NO308583B1 (en)
NZ (1) NZ261581A (en)
PL (1) PL182901B1 (en)
RU (1) RU2172740C2 (en)
WO (1) WO1994018224A1 (en)
ZA (1) ZA94715B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW403736B (en) * 1997-02-21 2000-09-01 Akzo Nobel Nv Steroid compounds having contraceptive and anti-osteoporosis activity
WO1999045886A2 (en) * 1998-03-09 1999-09-16 Akzo Nobel N.V. New contraceptive kit for monotherapy
US6677329B1 (en) 1999-09-06 2004-01-13 Akzo Nobel N V. Non-aromatic estrogenic steroids with a hydrocarbon substituent in position 11
SK882003A3 (en) 2000-07-28 2003-07-01 Akzo Nobel Nv 16alpha-substituted steroid compounds, pharmaceutical composition comprising same and their use
UA89964C2 (en) 2004-09-08 2010-03-25 Н.В. Органон 15beta-substituted steroids having selective estrogenic activity
ES2881336T3 (en) * 2016-03-03 2021-11-29 Crystal Pharma Sau Procedure and new intermediates for the preparation of 11-methylene steroids

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3325520A (en) * 1965-12-08 1967-06-13 Searle & Co (optionally 17-hydrocarbon-substituted) 11, 13beta-dialkylgon-4-en-3-ones and esters corresponding
US3465010A (en) * 1966-11-22 1969-09-02 Searle & Co 17 - (unsaturated hydrocarbon - substituted) 11,13beta - dialkylgon -4 - ene - 3,17beta-diols and esters thereof
US3927046A (en) * 1972-12-09 1975-12-16 Akzona Inc Novel 11,11-alkylidene steroids
NL175063C (en) * 1972-12-09 1984-09-17 Akzo Nv PROCESS FOR THE PREPARATION OF 11,11-ALKYLIDE STEROIDS, PROCESS FOR PREPARING PHARMACEUTICAL PREPARATIONS AND FORMED PHARMACEUTICAL PREPARATIONS.
NL7317358A (en) * 1973-12-19 1975-06-23 Akzo Nv NEW 11 (BETA) ALKYL STEROIDS FROM THE OESTRAAN SERIES.
NL7701384A (en) * 1977-02-10 1978-08-14 Akzo Nv PROCESS FOR PREPARING NEW STEROIDS FROM THE OESTRAINE SERIES.
AU532512B2 (en) * 1979-09-07 1983-10-06 Upjohn and Horton Anti-allergenic compounds for bone mineral resorption
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
AU572589B2 (en) * 1983-12-14 1988-05-12 Upjohn Company, The 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
NL8502571A (en) * 1985-09-20 1987-04-16 Akzo Nv Steroidal immuno-modulators - comprising 4-oestrene derivs.
DE3702383A1 (en) * 1987-01-23 1988-08-04 Schering Ag 11SS-ALKINYLESTRENE AND -ESTRADIENE, THEIR PRODUCTION AND THEIR PHARMACEUTICAL PREPARATIONS CONTAINING THEM
HUT52382A (en) * 1988-03-14 1990-07-28 Sandoz Ag Process for producing pharmaceutical compositions comprising as active ingredient unsubstituted progestin in 19-position and estrogen in the given case
DK0461290T3 (en) * 1990-06-14 1994-02-21 Henning Berlin Gmbh Liquid-filled sockets
AU8166191A (en) * 1990-08-10 1992-02-13 Ortho Pharmaceutical Corporation Method for treatment of bone wasting diseases

Also Published As

Publication number Publication date
HUT72971A (en) 1996-06-28
HU0102320D0 (en) 2001-08-28
AU682170B2 (en) 1997-09-25
BR9405825A (en) 1995-12-05
PL310125A1 (en) 1995-11-27
NO308583B1 (en) 2000-10-02
PL182901B1 (en) 2002-03-29
EP0682672A1 (en) 1995-11-22
NO953089D0 (en) 1995-08-07
NZ261581A (en) 1997-06-24
AU6039494A (en) 1994-08-29
CA2155532A1 (en) 1994-08-18
AU4675897A (en) 1998-02-19
FI953747A (en) 1995-09-12
FI114101B (en) 2004-08-13
CN1117735A (en) 1996-02-28
KR100364113B1 (en) 2003-04-08
RU2172740C2 (en) 2001-08-27
CN1046735C (en) 1999-11-24
FI953747A0 (en) 1995-08-07
JPH08506116A (en) 1996-07-02
HU9501940D0 (en) 1995-09-28
HU220615B1 (en) 2002-03-28
NO953089L (en) 1995-10-06
WO1994018224A1 (en) 1994-08-18

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