AU4675897A - Steroids for treating menopausal complaints - Google Patents

Steroids for treating menopausal complaints

Info

Publication number
AU4675897A
AU4675897A AU46758/97A AU4675897A AU4675897A AU 4675897 A AU4675897 A AU 4675897A AU 46758/97 A AU46758/97 A AU 46758/97A AU 4675897 A AU4675897 A AU 4675897A AU 4675897 A AU4675897 A AU 4675897A
Authority
AU
Australia
Prior art keywords
steroids
treating menopausal
menopausal complaints
complaints
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU46758/97A
Inventor
Hubert Jan Jozef Loozen
Jane Margretha Lena Pieters
Lodewijk Pieter Cornelis Schot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of AU4675897A publication Critical patent/AU4675897A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C07J33/007—Cyclic thioketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
AU46758/97A 1993-02-08 1997-11-28 Steroids for treating menopausal complaints Abandoned AU4675897A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93200332 1993-02-08
EP93200332 1993-02-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU60394/94A Division AU682170C (en) 1993-02-08 1994-02-04 Steroids for treating menopausal complaints

Publications (1)

Publication Number Publication Date
AU4675897A true AU4675897A (en) 1998-02-19

Family

ID=8213615

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46758/97A Abandoned AU4675897A (en) 1993-02-08 1997-11-28 Steroids for treating menopausal complaints

Country Status (15)

Country Link
EP (1) EP0682672A1 (en)
JP (1) JPH08506116A (en)
KR (1) KR100364113B1 (en)
CN (1) CN1046735C (en)
AU (1) AU4675897A (en)
BR (1) BR9405825A (en)
CA (1) CA2155532A1 (en)
FI (1) FI114101B (en)
HU (2) HU220615B1 (en)
NO (1) NO308583B1 (en)
NZ (1) NZ261581A (en)
PL (1) PL182901B1 (en)
RU (1) RU2172740C2 (en)
WO (1) WO1994018224A1 (en)
ZA (1) ZA94715B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW403736B (en) * 1997-02-21 2000-09-01 Akzo Nobel Nv Steroid compounds having contraceptive and anti-osteoporosis activity
WO1999045886A2 (en) * 1998-03-09 1999-09-16 Akzo Nobel N.V. New contraceptive kit for monotherapy
CA2382489C (en) * 1999-09-06 2008-03-11 Akzo Nobel N.V. Non-aromatic estrogenic steroids with a hydrocarbon substituent in position 11
US7696190B2 (en) 2000-07-28 2010-04-13 N.V. Organon 16Alpha-methyl or ethyl substituted estrogens
UA89964C2 (en) 2004-09-08 2010-03-25 Н.В. Органон 15beta-substituted steroids having selective estrogenic activity
JP7264569B2 (en) * 2016-03-03 2023-04-25 クリスタル ファルマ、エセ、ア、ウ Process and novel intermediates for the preparation of 11-methylene steroids

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3325520A (en) * 1965-12-08 1967-06-13 Searle & Co (optionally 17-hydrocarbon-substituted) 11, 13beta-dialkylgon-4-en-3-ones and esters corresponding
US3465010A (en) * 1966-11-22 1969-09-02 Searle & Co 17 - (unsaturated hydrocarbon - substituted) 11,13beta - dialkylgon -4 - ene - 3,17beta-diols and esters thereof
US3927046A (en) * 1972-12-09 1975-12-16 Akzona Inc Novel 11,11-alkylidene steroids
NL175063C (en) * 1972-12-09 1984-09-17 Akzo Nv PROCESS FOR THE PREPARATION OF 11,11-ALKYLIDE STEROIDS, PROCESS FOR PREPARING PHARMACEUTICAL PREPARATIONS AND FORMED PHARMACEUTICAL PREPARATIONS.
NL7317358A (en) * 1973-12-19 1975-06-23 Akzo Nv NEW 11 (BETA) ALKYL STEROIDS FROM THE OESTRAAN SERIES.
NL7701384A (en) * 1977-02-10 1978-08-14 Akzo Nv PROCESS FOR PREPARING NEW STEROIDS FROM THE OESTRAINE SERIES.
AU532512B2 (en) * 1979-09-07 1983-10-06 Upjohn and Horton Anti-allergenic compounds for bone mineral resorption
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
AU572589B2 (en) * 1983-12-14 1988-05-12 Upjohn Company, The 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
NL8502571A (en) * 1985-09-20 1987-04-16 Akzo Nv Steroidal immuno-modulators - comprising 4-oestrene derivs.
DE3702383A1 (en) * 1987-01-23 1988-08-04 Schering Ag 11SS-ALKINYLESTRENE AND -ESTRADIENE, THEIR PRODUCTION AND THEIR PHARMACEUTICAL PREPARATIONS CONTAINING THEM
HUT52382A (en) * 1988-03-14 1990-07-28 Sandoz Ag Process for producing pharmaceutical compositions comprising as active ingredient unsubstituted progestin in 19-position and estrogen in the given case
ATE99939T1 (en) * 1990-06-14 1994-01-15 Henning Berlin Gmbh LIQUID-FILLED CAPSULE PREPARATIONS.
AU8166191A (en) * 1990-08-10 1992-02-13 Ortho Pharmaceutical Corporation Method for treatment of bone wasting diseases

Also Published As

Publication number Publication date
NZ261581A (en) 1997-06-24
FI953747A0 (en) 1995-08-07
CN1117735A (en) 1996-02-28
HUT72971A (en) 1996-06-28
CN1046735C (en) 1999-11-24
FI953747A (en) 1995-09-12
RU2172740C2 (en) 2001-08-27
AU682170B2 (en) 1997-09-25
ZA94715B (en) 1994-10-24
WO1994018224A1 (en) 1994-08-18
AU6039494A (en) 1994-08-29
NO953089D0 (en) 1995-08-07
KR100364113B1 (en) 2003-04-08
NO953089L (en) 1995-10-06
HU220615B1 (en) 2002-03-28
BR9405825A (en) 1995-12-05
PL182901B1 (en) 2002-03-29
FI114101B (en) 2004-08-13
HU0102320D0 (en) 2001-08-28
PL310125A1 (en) 1995-11-27
CA2155532A1 (en) 1994-08-18
HU9501940D0 (en) 1995-09-28
JPH08506116A (en) 1996-07-02
EP0682672A1 (en) 1995-11-22
NO308583B1 (en) 2000-10-02

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted