FI951367A0 - Puriinijohdannaiset ja tulehdustautien tukahduttajat (suppressantit) - Google Patents

Puriinijohdannaiset ja tulehdustautien tukahduttajat (suppressantit)

Info

Publication number
FI951367A0
FI951367A0 FI951367A FI951367A FI951367A0 FI 951367 A0 FI951367 A0 FI 951367A0 FI 951367 A FI951367 A FI 951367A FI 951367 A FI951367 A FI 951367A FI 951367 A0 FI951367 A0 FI 951367A0
Authority
FI
Finland
Prior art keywords
suppressants
infectious diseases
purine derivatives
purine
derivatives
Prior art date
Application number
FI951367A
Other languages
English (en)
Swedish (sv)
Other versions
FI951367A (fi
Inventor
Yoshiki Isobe
Nobuyoshi Chiba
Yuso Goto
Hideharu Sato
Original Assignee
Japan Energy Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP7465195A external-priority patent/JPH07316157A/ja
Priority claimed from JP7739495A external-priority patent/JP3491711B2/ja
Application filed by Japan Energy Corp filed Critical Japan Energy Corp
Publication of FI951367A0 publication Critical patent/FI951367A0/fi
Publication of FI951367A publication Critical patent/FI951367A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28Oxygen atom
    • C07D473/30Oxygen atom attached in position 6, e.g. hypoxanthine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI951367A 1994-03-28 1995-03-23 Puriinijohdannaiset ja tulehdustautien tukahduttajat (suppressantit) FI951367A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8100094 1994-03-28
JP7465195A JPH07316157A (ja) 1994-03-28 1995-03-07 ヒポキサンチン誘導体及び炎症性疾患の抑制剤
JP7739495A JP3491711B2 (ja) 1994-03-28 1995-03-08 プリン誘導体及び炎症性疾患の抑制剤

Publications (2)

Publication Number Publication Date
FI951367A0 true FI951367A0 (fi) 1995-03-23
FI951367A FI951367A (fi) 1995-09-29

Family

ID=27301573

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951367A FI951367A (fi) 1994-03-28 1995-03-23 Puriinijohdannaiset ja tulehdustautien tukahduttajat (suppressantit)

Country Status (4)

Country Link
US (1) US5602140A (fi)
EP (1) EP0675124A3 (fi)
FI (1) FI951367A (fi)
NO (1) NO307608B1 (fi)

Families Citing this family (34)

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Publication number Priority date Publication date Assignee Title
GB9312853D0 (en) 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US6166041A (en) 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) * 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US6294541B1 (en) 1996-06-06 2001-09-25 Euro-Celtique S.A. Purine derivatives having phosphodiesterase IV inhibition activity
NZ502752A (en) 1997-07-15 2001-01-26 Japan Energy Corp Purine derivatives and their use in the treatment of nephritis
US6037470A (en) 1997-12-12 2000-03-14 Euro-Celtique S.A. Purine compounds having PDE IV inhibitory activity and methods of synthesis
US6319928B1 (en) 1998-11-30 2001-11-20 Euro-Celtique, S.A. Purine derivatives having phosphodiesterase IV inhibition activity
CN1377353A (zh) 1999-04-02 2002-10-30 欧罗赛铁克股份有限公司 具有磷酸二酯酶iv抑制活性的嘌呤衍生物
GB9924020D0 (en) 1999-10-11 1999-12-15 Pfizer Ltd Pharmaceutically active compounds
JP2003513756A (ja) * 1999-11-12 2003-04-15 アンジオテック ファーマシューティカルズ,インコーポレイテッド 放射性治療と細胞周期インヒビターとの組合せの組成物
US6667300B2 (en) 2000-04-25 2003-12-23 Icos Corporation Inhibitors of human phosphatidylinositol 3-kinase delta
EP1939203B1 (en) * 2000-04-25 2014-11-19 ICOS Corporation Inhibitors of human phosphatidyl-inositol 3-kinase delta isoform
EP1278748B1 (en) * 2000-04-25 2011-03-23 ICOS Corporation Inhibitors of human phosphatidyl-inositol 3-kinase delta
US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
ATE457716T1 (de) 2002-12-30 2010-03-15 Angiotech Int Ag Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
LT2612862T (lt) 2004-05-13 2017-01-25 Icos Corporation Chinazolinonai kaip žmogaus fosfatidilinozitol-3-kinazės delta inhibitoriai
US20060046877A1 (en) * 2004-08-31 2006-03-02 Gajda William G Jr Foam projectile with suction cup tip
WO2008092860A1 (en) * 2007-01-30 2008-08-07 Janssen Pharmaceutica N.V. Bicyclic derivatives as ep4 agonists
WO2008092862A1 (en) * 2007-01-30 2008-08-07 Janssen Pharmaceutica N.V. Bicyclic derivatives as ep4 agonists
WO2008092861A1 (en) * 2007-01-30 2008-08-07 Janssen Pharmaceutica N.V. Bicyclic derivatives as ep4 agonists
US9492449B2 (en) 2008-11-13 2016-11-15 Gilead Calistoga Llc Therapies for hematologic malignancies
KR20170060179A (ko) 2008-11-13 2017-05-31 길리아드 칼리스토가 엘엘씨 혈액 종양에 대한 요법
KR20120002995A (ko) 2009-03-24 2012-01-09 길리아드 칼리스토가 엘엘씨 2―퓨리닐―3―톨릴―퀴나졸리논 유도체의 회전장애 이성질체 및 사용 방법
SG175259A1 (en) 2009-04-20 2011-11-28 Gilead Calistoga Llc Methods of treatment for solid tumors
KR20120049281A (ko) 2009-07-21 2012-05-16 길리아드 칼리스토가 엘엘씨 Pi3k 억제제를 이용한 간 장애의 치료
WO2011106168A1 (en) * 2010-02-24 2011-09-01 Dcam Pharma Inc Purine compounds for treating autoimmune and demyelinating diseases
EP2713737B1 (en) * 2011-06-01 2016-04-20 Janus Biotherapeutics, Inc. Novel immune system modulators
KR20140133590A (ko) 2012-03-05 2014-11-19 길리아드 칼리스토가 엘엘씨 (s)-2-(1-(9h-퓨린-6-일아미노)프로필)-5-플루오로-3-페닐퀴나졸린-4(3h)-온의 다형체 형태
EP3594215A1 (en) 2013-12-20 2020-01-15 Gilead Calistoga LLC Intermediate products in process methods for the preparation of phosphatidylinositol 3-kinase inhibitors
EP3083623A1 (en) 2013-12-20 2016-10-26 Gilead Calistoga LLC Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
EP3154960A1 (en) 2014-06-13 2017-04-19 Gilead Sciences, Inc. Phosphatidylinositol 3-kinase inhibitors

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IT1153293B (it) * 1982-10-22 1987-01-14 Francia Famaceutici S R L Derivati del 4-idrossi-2-metil-2h-1, 2-benzotiazina-3-carbossamide 1, 1-biossido e procedimento per la loro preparazione
US5098906A (en) * 1983-10-31 1992-03-24 Warner-Lambert Company Purine derivatives
JPS60260579A (ja) * 1984-01-13 1985-12-23 Yoshitomi Pharmaceut Ind Ltd プリン誘導体
US4772606A (en) * 1985-08-22 1988-09-20 Warner-Lambert Company Purine derivatives
US5272153A (en) * 1986-12-31 1993-12-21 Hoechst-Roussel Pharmaceuticals, Inc. Method of inhibiting the activity of leukocyte derived cytokines
CA1303037C (en) * 1987-02-02 1992-06-09 Smith Kline & French Laboratories Limited Purinone derivatives as bronchodilators vasodilators and anti-allergic agents
US4975467A (en) * 1987-03-17 1990-12-04 Merrell Dow Pharmaceuticals Inc. Method of inhibiting interleukin-1 release and alleviating interleukin-1 mediated conditions
DE3869202D1 (de) * 1987-03-17 1992-04-23 Merrell Dow Pharma Alkylidendithiobis (substituierte) phenolen zur hemmung der freisetzung von interleukin-1 und zur linderung von interleukin-1 vermittelten krankheiten.
GB8817651D0 (en) * 1988-07-25 1988-09-01 Smith Kline French Lab Chemical compounds
FI93954C (fi) * 1988-11-29 1995-06-26 Warner Lambert Co Menetelmä lääkeaineina käyttökelpoisten 3,5-di-tert-butyyli-4-hydroksifenyylisubstituoitujen 1,2,4- ja 1,3,4-tiadiatsolien sekä oksadiatsolien ja triatsolien valmistamiseksi
US5270465A (en) * 1989-03-30 1993-12-14 Lipha, Lyonnaise Industrille Pharmaceutique 4(3H)-pteridinone compounds
GB8928346D0 (en) * 1989-12-15 1990-02-21 Smith Kline French Lab Chemical compounds
US5250534A (en) * 1990-06-20 1993-10-05 Pfizer Inc. Pyrazolopyrimidinone antianginal agents
GB9213623D0 (en) * 1992-06-26 1992-08-12 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
NO951165D0 (no) 1995-03-27
NO951165L (no) 1995-09-29
EP0675124A2 (en) 1995-10-04
FI951367A (fi) 1995-09-29
EP0675124A3 (en) 1996-08-21
NO307608B1 (no) 2000-05-02
US5602140A (en) 1997-02-11

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