FI951367A0 - Puriinijohdannaiset ja tulehdustautien tukahduttajat (suppressantit) - Google Patents
Puriinijohdannaiset ja tulehdustautien tukahduttajat (suppressantit)Info
- Publication number
- FI951367A0 FI951367A0 FI951367A FI951367A FI951367A0 FI 951367 A0 FI951367 A0 FI 951367A0 FI 951367 A FI951367 A FI 951367A FI 951367 A FI951367 A FI 951367A FI 951367 A0 FI951367 A0 FI 951367A0
- Authority
- FI
- Finland
- Prior art keywords
- suppressants
- infectious diseases
- purine derivatives
- purine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
- C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8100094 | 1994-03-28 | ||
JP7465195A JPH07316157A (ja) | 1994-03-28 | 1995-03-07 | ヒポキサンチン誘導体及び炎症性疾患の抑制剤 |
JP7739495A JP3491711B2 (ja) | 1994-03-28 | 1995-03-08 | プリン誘導体及び炎症性疾患の抑制剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI951367A0 true FI951367A0 (fi) | 1995-03-23 |
FI951367A FI951367A (fi) | 1995-09-29 |
Family
ID=27301573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI951367A FI951367A (fi) | 1994-03-28 | 1995-03-23 | Puriinijohdannaiset ja tulehdustautien tukahduttajat (suppressantit) |
Country Status (4)
Country | Link |
---|---|
US (1) | US5602140A (fi) |
EP (1) | EP0675124A3 (fi) |
FI (1) | FI951367A (fi) |
NO (1) | NO307608B1 (fi) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9312853D0 (en) | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
US5591776A (en) | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
US5922751A (en) | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
US6166041A (en) | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
US6075016A (en) | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
US5864037A (en) * | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
US6294541B1 (en) | 1996-06-06 | 2001-09-25 | Euro-Celtique S.A. | Purine derivatives having phosphodiesterase IV inhibition activity |
NZ502752A (en) | 1997-07-15 | 2001-01-26 | Japan Energy Corp | Purine derivatives and their use in the treatment of nephritis |
US6037470A (en) | 1997-12-12 | 2000-03-14 | Euro-Celtique S.A. | Purine compounds having PDE IV inhibitory activity and methods of synthesis |
US6319928B1 (en) | 1998-11-30 | 2001-11-20 | Euro-Celtique, S.A. | Purine derivatives having phosphodiesterase IV inhibition activity |
CN1377353A (zh) | 1999-04-02 | 2002-10-30 | 欧罗赛铁克股份有限公司 | 具有磷酸二酯酶iv抑制活性的嘌呤衍生物 |
GB9924020D0 (en) | 1999-10-11 | 1999-12-15 | Pfizer Ltd | Pharmaceutically active compounds |
JP2003513756A (ja) * | 1999-11-12 | 2003-04-15 | アンジオテック ファーマシューティカルズ,インコーポレイテッド | 放射性治療と細胞周期インヒビターとの組合せの組成物 |
US6667300B2 (en) | 2000-04-25 | 2003-12-23 | Icos Corporation | Inhibitors of human phosphatidylinositol 3-kinase delta |
EP1939203B1 (en) * | 2000-04-25 | 2014-11-19 | ICOS Corporation | Inhibitors of human phosphatidyl-inositol 3-kinase delta isoform |
EP1278748B1 (en) * | 2000-04-25 | 2011-03-23 | ICOS Corporation | Inhibitors of human phosphatidyl-inositol 3-kinase delta |
US20030216758A1 (en) * | 2001-12-28 | 2003-11-20 | Angiotech Pharmaceuticals, Inc. | Coated surgical patches |
ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
LT2612862T (lt) | 2004-05-13 | 2017-01-25 | Icos Corporation | Chinazolinonai kaip žmogaus fosfatidilinozitol-3-kinazės delta inhibitoriai |
US20060046877A1 (en) * | 2004-08-31 | 2006-03-02 | Gajda William G Jr | Foam projectile with suction cup tip |
WO2008092860A1 (en) * | 2007-01-30 | 2008-08-07 | Janssen Pharmaceutica N.V. | Bicyclic derivatives as ep4 agonists |
WO2008092862A1 (en) * | 2007-01-30 | 2008-08-07 | Janssen Pharmaceutica N.V. | Bicyclic derivatives as ep4 agonists |
WO2008092861A1 (en) * | 2007-01-30 | 2008-08-07 | Janssen Pharmaceutica N.V. | Bicyclic derivatives as ep4 agonists |
US9492449B2 (en) | 2008-11-13 | 2016-11-15 | Gilead Calistoga Llc | Therapies for hematologic malignancies |
KR20170060179A (ko) | 2008-11-13 | 2017-05-31 | 길리아드 칼리스토가 엘엘씨 | 혈액 종양에 대한 요법 |
KR20120002995A (ko) | 2009-03-24 | 2012-01-09 | 길리아드 칼리스토가 엘엘씨 | 2―퓨리닐―3―톨릴―퀴나졸리논 유도체의 회전장애 이성질체 및 사용 방법 |
SG175259A1 (en) | 2009-04-20 | 2011-11-28 | Gilead Calistoga Llc | Methods of treatment for solid tumors |
KR20120049281A (ko) | 2009-07-21 | 2012-05-16 | 길리아드 칼리스토가 엘엘씨 | Pi3k 억제제를 이용한 간 장애의 치료 |
WO2011106168A1 (en) * | 2010-02-24 | 2011-09-01 | Dcam Pharma Inc | Purine compounds for treating autoimmune and demyelinating diseases |
EP2713737B1 (en) * | 2011-06-01 | 2016-04-20 | Janus Biotherapeutics, Inc. | Novel immune system modulators |
KR20140133590A (ko) | 2012-03-05 | 2014-11-19 | 길리아드 칼리스토가 엘엘씨 | (s)-2-(1-(9h-퓨린-6-일아미노)프로필)-5-플루오로-3-페닐퀴나졸린-4(3h)-온의 다형체 형태 |
EP3594215A1 (en) | 2013-12-20 | 2020-01-15 | Gilead Calistoga LLC | Intermediate products in process methods for the preparation of phosphatidylinositol 3-kinase inhibitors |
EP3083623A1 (en) | 2013-12-20 | 2016-10-26 | Gilead Calistoga LLC | Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one |
EP3154960A1 (en) | 2014-06-13 | 2017-04-19 | Gilead Sciences, Inc. | Phosphatidylinositol 3-kinase inhibitors |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1153293B (it) * | 1982-10-22 | 1987-01-14 | Francia Famaceutici S R L | Derivati del 4-idrossi-2-metil-2h-1, 2-benzotiazina-3-carbossamide 1, 1-biossido e procedimento per la loro preparazione |
US5098906A (en) * | 1983-10-31 | 1992-03-24 | Warner-Lambert Company | Purine derivatives |
JPS60260579A (ja) * | 1984-01-13 | 1985-12-23 | Yoshitomi Pharmaceut Ind Ltd | プリン誘導体 |
US4772606A (en) * | 1985-08-22 | 1988-09-20 | Warner-Lambert Company | Purine derivatives |
US5272153A (en) * | 1986-12-31 | 1993-12-21 | Hoechst-Roussel Pharmaceuticals, Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
CA1303037C (en) * | 1987-02-02 | 1992-06-09 | Smith Kline & French Laboratories Limited | Purinone derivatives as bronchodilators vasodilators and anti-allergic agents |
US4975467A (en) * | 1987-03-17 | 1990-12-04 | Merrell Dow Pharmaceuticals Inc. | Method of inhibiting interleukin-1 release and alleviating interleukin-1 mediated conditions |
DE3869202D1 (de) * | 1987-03-17 | 1992-04-23 | Merrell Dow Pharma | Alkylidendithiobis (substituierte) phenolen zur hemmung der freisetzung von interleukin-1 und zur linderung von interleukin-1 vermittelten krankheiten. |
GB8817651D0 (en) * | 1988-07-25 | 1988-09-01 | Smith Kline French Lab | Chemical compounds |
FI93954C (fi) * | 1988-11-29 | 1995-06-26 | Warner Lambert Co | Menetelmä lääkeaineina käyttökelpoisten 3,5-di-tert-butyyli-4-hydroksifenyylisubstituoitujen 1,2,4- ja 1,3,4-tiadiatsolien sekä oksadiatsolien ja triatsolien valmistamiseksi |
US5270465A (en) * | 1989-03-30 | 1993-12-14 | Lipha, Lyonnaise Industrille Pharmaceutique | 4(3H)-pteridinone compounds |
GB8928346D0 (en) * | 1989-12-15 | 1990-02-21 | Smith Kline French Lab | Chemical compounds |
US5250534A (en) * | 1990-06-20 | 1993-10-05 | Pfizer Inc. | Pyrazolopyrimidinone antianginal agents |
GB9213623D0 (en) * | 1992-06-26 | 1992-08-12 | Pfizer Ltd | Therapeutic agents |
-
1995
- 1995-03-23 FI FI951367A patent/FI951367A/fi unknown
- 1995-03-24 EP EP95301978A patent/EP0675124A3/en not_active Withdrawn
- 1995-03-27 NO NO951165A patent/NO307608B1/no not_active IP Right Cessation
- 1995-03-27 US US08/410,838 patent/US5602140A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO951165D0 (no) | 1995-03-27 |
NO951165L (no) | 1995-09-29 |
EP0675124A2 (en) | 1995-10-04 |
FI951367A (fi) | 1995-09-29 |
EP0675124A3 (en) | 1996-08-21 |
NO307608B1 (no) | 2000-05-02 |
US5602140A (en) | 1997-02-11 |
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