FI951193L - Ei-metabolisoituvat klomifeenianalogit tamoksifeeniresistenttien kasvainten hoitamiseksi - Google Patents
Ei-metabolisoituvat klomifeenianalogit tamoksifeeniresistenttien kasvainten hoitamiseksi Download PDFInfo
- Publication number
- FI951193L FI951193L FI951193A FI951193A FI951193L FI 951193 L FI951193 L FI 951193L FI 951193 A FI951193 A FI 951193A FI 951193 A FI951193 A FI 951193A FI 951193 L FI951193 L FI 951193L
- Authority
- FI
- Finland
- Prior art keywords
- metabolizable
- tamoxifen
- treatment
- resistant tumors
- clomiphene analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/45—Monoamines
- C07C211/48—N-alkylated amines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94530592A | 1992-09-15 | 1992-09-15 | |
| PCT/US1993/007697 WO1994006762A1 (en) | 1992-09-15 | 1993-08-16 | Non-metabolizable clomiphene analogs for treatment of tamoxifen-resistant tumors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI951193A7 FI951193A7 (fi) | 1995-03-14 |
| FI951193A0 FI951193A0 (fi) | 1995-03-14 |
| FI951193L true FI951193L (fi) | 1995-03-14 |
Family
ID=25482938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI951193A FI951193L (fi) | 1992-09-15 | 1993-08-16 | Ei-metabolisoituvat klomifeenianalogit tamoksifeeniresistenttien kasvainten hoitamiseksi |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US5410080A (da) |
| EP (1) | EP0660821B1 (da) |
| JP (1) | JPH09500863A (da) |
| KR (1) | KR100326962B1 (da) |
| AT (1) | ATE162516T1 (da) |
| AU (1) | AU672234B2 (da) |
| CA (1) | CA2143000C (da) |
| DE (1) | DE69316633T2 (da) |
| DK (1) | DK0660821T3 (da) |
| ES (1) | ES2112994T3 (da) |
| FI (1) | FI951193L (da) |
| GR (1) | GR3026236T3 (da) |
| HU (1) | HUT71244A (da) |
| NO (1) | NO950985L (da) |
| NZ (1) | NZ255785A (da) |
| WO (1) | WO1994006762A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR008155A1 (es) * | 1996-09-06 | 1999-12-09 | Smithkline Beecham Corp | Uso de un compuesto de formula i para preparar un medicamento util para tratar y prevenir la enfermedad cardiovascular post menopausica en mujeres. |
| DE69840126D1 (de) | 1997-08-15 | 2008-11-27 | Univ Duke | Verfahren zur prophylaxis oder behandlung von östrogen-abhängigen krankheiten |
| UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
| HK1216502A1 (zh) | 2012-11-02 | 2016-11-18 | Repros Therapeutics Inc. | 用於癌症治療的反式-克羅米芬 |
| MX2016011567A (es) | 2014-03-11 | 2016-12-07 | Repros Therapeutics Inc | Sintesis de clomifeno usando un solvente unico. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2750416A (en) * | 1950-12-21 | 1956-06-12 | Rohm & Haas | Aminomethylphenols and method for their preparation |
| US3143568A (en) * | 1961-01-25 | 1964-08-04 | Vismara Francesco Spa | Diarylamino-acetyl-aryl derivatives |
| US3244705A (en) * | 1962-11-14 | 1966-04-05 | Richardson Merrell Inc | Triphenylhaloethylene derivatives |
| CH373975A (de) * | 1963-07-20 | 1963-12-15 | Heierle Werner | Kronen-Verschluss für Flaschen |
| FR3575M (fr) * | 1964-01-28 | 1965-10-04 | Richardson Merrell | Triphénylhalogénoéthylenes substitués. |
| US3631109A (en) * | 1968-12-04 | 1971-12-28 | Uniroyal Inc | Beta beta'-bis(dialkylaminomethyl-4-hydroxy-benzylthio)dialkylethers |
| GB2126576B (en) * | 1982-06-25 | 1985-06-19 | Farmos Group Limited | Alkane and alkene derivatives |
| DE3762617D1 (de) * | 1986-09-11 | 1990-06-13 | Nat Res Dev | Tamoxifenderivate. |
| US5114951A (en) * | 1989-04-11 | 1992-05-19 | Burroughs Wellcome Company | Agents for combating multiple drug resistance |
| US5130424A (en) * | 1990-08-01 | 1992-07-14 | Merrell Dow Pharmaceuticals Inc. | 4-amino-delta-4,6-steroids and their use as 5 alpha-reductase inhibitors |
-
1993
- 1993-08-16 FI FI951193A patent/FI951193L/fi not_active Application Discontinuation
- 1993-08-16 CA CA002143000A patent/CA2143000C/en not_active Expired - Fee Related
- 1993-08-16 KR KR1019950700991A patent/KR100326962B1/ko not_active Expired - Fee Related
- 1993-08-16 HU HU9500775A patent/HUT71244A/hu unknown
- 1993-08-16 NZ NZ255785A patent/NZ255785A/en unknown
- 1993-08-16 JP JP6508081A patent/JPH09500863A/ja not_active Ceased
- 1993-08-16 ES ES93920100T patent/ES2112994T3/es not_active Expired - Lifetime
- 1993-08-16 AT AT93920100T patent/ATE162516T1/de not_active IP Right Cessation
- 1993-08-16 AU AU50150/93A patent/AU672234B2/en not_active Ceased
- 1993-08-16 EP EP93920100A patent/EP0660821B1/en not_active Expired - Lifetime
- 1993-08-16 WO PCT/US1993/007697 patent/WO1994006762A1/en not_active Ceased
- 1993-08-16 DE DE69316633T patent/DE69316633T2/de not_active Expired - Fee Related
- 1993-08-16 DK DK93920100T patent/DK0660821T3/da active
-
1994
- 1994-02-10 US US08/196,817 patent/US5410080A/en not_active Expired - Fee Related
- 1994-12-05 US US08/350,192 patent/US5681863A/en not_active Expired - Fee Related
-
1995
- 1995-03-14 NO NO950985A patent/NO950985L/no not_active Application Discontinuation
-
1998
- 1998-02-25 GR GR980400417T patent/GR3026236T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ255785A (en) | 1997-05-26 |
| WO1994006762A1 (en) | 1994-03-31 |
| KR100326962B1 (ko) | 2002-12-02 |
| KR950703524A (ko) | 1995-09-20 |
| EP0660821A1 (en) | 1995-07-05 |
| FI951193A7 (fi) | 1995-03-14 |
| ES2112994T3 (es) | 1998-04-16 |
| DE69316633D1 (de) | 1998-02-26 |
| AU672234B2 (en) | 1996-09-26 |
| CA2143000A1 (en) | 1994-03-31 |
| HUT71244A (en) | 1995-11-28 |
| JPH09500863A (ja) | 1997-01-28 |
| DE69316633T2 (de) | 1998-05-20 |
| US5410080A (en) | 1995-04-25 |
| FI951193A0 (fi) | 1995-03-14 |
| NO950985D0 (no) | 1995-03-14 |
| NO950985L (no) | 1995-03-14 |
| GR3026236T3 (en) | 1998-05-29 |
| ATE162516T1 (de) | 1998-02-15 |
| US5681863A (en) | 1997-10-28 |
| DK0660821T3 (da) | 1998-09-21 |
| EP0660821B1 (en) | 1998-01-21 |
| HU9500775D0 (en) | 1995-05-29 |
| CA2143000C (en) | 2000-03-28 |
| AU5015093A (en) | 1994-04-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |