FI944561A0 - HIV neutraliserande monoklonala rekombinanthumanantikroppar för prevention och behandling av HIV-infektion - Google Patents

HIV neutraliserande monoklonala rekombinanthumanantikroppar för prevention och behandling av HIV-infektion

Info

Publication number
FI944561A0
FI944561A0 FI944561A FI944561A FI944561A0 FI 944561 A0 FI944561 A0 FI 944561A0 FI 944561 A FI944561 A FI 944561A FI 944561 A FI944561 A FI 944561A FI 944561 A0 FI944561 A0 FI 944561A0
Authority
FI
Finland
Prior art keywords
hiv
prevention
treatment
monoclonal antibodies
recombinant human
Prior art date
Application number
FI944561A
Other languages
English (en)
Finnish (fi)
Other versions
FI944561A (sv
Inventor
Emilio A Emini
Anthony J Conley
George E Mark
L Syd Johnson
David S Pfarr
Original Assignee
Merck & Co Inc
Medimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc, Medimmune Inc filed Critical Merck & Co Inc
Publication of FI944561A publication Critical patent/FI944561A/sv
Publication of FI944561A0 publication Critical patent/FI944561A0/sv

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI944561A 1992-04-01 1994-09-30 HIV neutraliserande monoklonala rekombinanthumanantikroppar för prevention och behandling av HIV-infektion FI944561A0 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86170192A 1992-04-01 1992-04-01
PCT/US1993/002629 WO1993019785A1 (en) 1992-04-01 1993-03-23 Recombinant human hiv-neutralizing monoclonal antibodies for prevention and treatment of hiv infection

Publications (2)

Publication Number Publication Date
FI944561A FI944561A (sv) 1994-09-30
FI944561A0 true FI944561A0 (sv) 1994-09-30

Family

ID=25336532

Family Applications (1)

Application Number Title Priority Date Filing Date
FI944561A FI944561A0 (sv) 1992-04-01 1994-09-30 HIV neutraliserande monoklonala rekombinanthumanantikroppar för prevention och behandling av HIV-infektion

Country Status (19)

Country Link
EP (1) EP0577243A3 (sv)
JP (1) JPH06217791A (sv)
KR (1) KR950700761A (sv)
CN (1) CN1081716A (sv)
AU (2) AU3928593A (sv)
BG (1) BG99074A (sv)
CA (1) CA2093099A1 (sv)
CZ (1) CZ239694A3 (sv)
FI (1) FI944561A0 (sv)
HU (1) HUT70461A (sv)
IL (1) IL105145A0 (sv)
MX (1) MX9301858A (sv)
NO (1) NO943653L (sv)
NZ (1) NZ251582A (sv)
RU (1) RU94045907A (sv)
SK (1) SK116294A3 (sv)
WO (1) WO1993019785A1 (sv)
YU (1) YU22693A (sv)
ZA (1) ZA932308B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ511291A (en) * 1998-10-30 2003-08-29 Novozymes As A method for selecting a protein variant that has reduced immunogenicity as compared with the parent or wild-type protein
US7560529B2 (en) 2001-04-24 2009-07-14 FDS Pharma Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence
RU2221873C2 (ru) * 2001-04-24 2004-01-20 Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" Способ получения каталитических антител (варианты), антигены для иммунизации и нуклеотидная последовательность
FR2844455B1 (fr) * 2002-09-13 2007-12-14 Lab Francais Du Fractionnement Traitement des pathologies echappant a la reponse immune par des anticorps optimises
US8332159B2 (en) 2003-02-20 2012-12-11 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Method for enhancing efficacy of preparation of monoclonal antibody
WO2009029569A1 (en) * 2007-08-24 2009-03-05 Novartis Vaccines And Diagnostics Inc. Hiv env proteins with modifications in the v3 loop
AU2009333559B2 (en) 2008-12-09 2015-03-12 Gilead Sciences, Inc. Modulators of toll-like receptors
WO2015117008A2 (en) * 2014-01-31 2015-08-06 The Rockefeller University Broadly neutralizing anti-hiv antibodies and epitope therefor
TWI733652B (zh) * 2014-07-11 2021-07-21 美商基利科學股份有限公司 用於治療HIV之toll樣受體調節劑
EP3194401B1 (en) 2014-09-16 2020-10-21 Gilead Sciences, Inc. Solid forms of a toll-like receptor modulator
WO2021227138A1 (zh) * 2020-05-09 2021-11-18 江苏省疾病预防控制中心(江苏省公共卫生研究院) 针对新型冠状病毒的单克隆抗体或其抗原结合部分

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE122237T1 (de) * 1987-05-29 1995-05-15 Tanox Biosystems Inc Hiv-1 neutralisierende monoklonale antikörper.
EP0311228A3 (en) * 1987-10-09 1990-05-02 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
CA2058630A1 (en) * 1989-06-05 1990-12-06 Charles F. Scott, Jr. Human monoclonal antibodies to hiv-1 mn gp 120
EP0535154A4 (en) * 1990-06-15 1993-12-01 New York University Heterohybridomas producing human monoclonal antibodies to hiv-1
CA2128879A1 (en) * 1992-01-29 1993-08-05 Marie E. Beckner Aamp-1, a protein with local homologies to hiv-1 env and nef proteins

Also Published As

Publication number Publication date
NO943653D0 (no) 1994-09-30
AU3563093A (en) 1993-10-07
RU94045907A (ru) 1996-11-10
EP0577243A3 (en) 1994-11-02
NO943653L (no) 1994-11-30
SK116294A3 (en) 1996-11-06
HUT70461A (en) 1995-10-30
FI944561A (sv) 1994-09-30
IL105145A0 (en) 1993-07-08
CA2093099A1 (en) 1993-10-02
NZ251582A (en) 1997-07-27
JPH06217791A (ja) 1994-08-09
AU3928593A (en) 1993-11-08
YU22693A (sh) 1997-01-08
WO1993019785A1 (en) 1993-10-14
KR950700761A (ko) 1995-02-20
AU658987B2 (en) 1995-05-04
HU9402824D0 (en) 1994-11-28
CN1081716A (zh) 1994-02-09
MX9301858A (es) 1994-03-31
EP0577243A2 (en) 1994-01-05
CZ239694A3 (en) 1995-07-12
BG99074A (en) 1995-11-30
ZA932308B (en) 1994-09-30

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