FI94049B - Förfarande för framställning av terapeutiskt användbara N-(3-hydroxi-4-piperidinyl)bensamider - Google Patents

Förfarande för framställning av terapeutiskt användbara N-(3-hydroxi-4-piperidinyl)bensamider

Info

Publication number
FI94049B
FI94049B FI883378A FI883378A FI94049B FI 94049 B FI94049 B FI 94049B FI 883378 A FI883378 A FI 883378A FI 883378 A FI883378 A FI 883378A FI 94049 B FI94049 B FI 94049B
Authority
FI
Finland
Prior art keywords
6alkyl
hydroxy
hydrogen
compounds
piperidinyl
Prior art date
Application number
FI883378A
Other languages
English (en)
Finnish (fi)
Other versions
FI883378A0 (sv
FI883378A (sv
FI94049C (sv
Inventor
Daele Georges Henri Paul Van
Freddy Francois Vlaeminck
Loon Karel Joannes Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI883378A0 publication Critical patent/FI883378A0/sv
Publication of FI883378A publication Critical patent/FI883378A/sv
Publication of FI94049B publication Critical patent/FI94049B/sv
Application granted granted Critical
Publication of FI94049C publication Critical patent/FI94049C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
FI883378A 1987-07-17 1988-07-15 Förfarande för framställning av terapeutiskt användbara N-(3-hydroxi-4-piperidinyl)bensamider FI94049C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7484587A 1987-07-17 1987-07-17
US7484587 1987-07-17

Publications (4)

Publication Number Publication Date
FI883378A0 FI883378A0 (sv) 1988-07-15
FI883378A FI883378A (sv) 1989-01-18
FI94049B true FI94049B (sv) 1995-03-31
FI94049C FI94049C (sv) 1995-07-10

Family

ID=22122023

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883378A FI94049C (sv) 1987-07-17 1988-07-15 Förfarande för framställning av terapeutiskt användbara N-(3-hydroxi-4-piperidinyl)bensamider

Country Status (23)

Country Link
EP (1) EP0299566B1 (sv)
JP (1) JP2642955B2 (sv)
KR (1) KR970011156B1 (sv)
CN (1) CN1020900C (sv)
AT (1) ATE111098T1 (sv)
AU (1) AU608338B2 (sv)
BG (1) BG48809A3 (sv)
CA (1) CA1317951C (sv)
DE (1) DE3851388T2 (sv)
DK (1) DK396088A (sv)
ES (1) ES2064341T3 (sv)
FI (1) FI94049C (sv)
HU (1) HU201926B (sv)
IE (1) IE64469B1 (sv)
IL (1) IL87129A (sv)
MA (1) MA21327A1 (sv)
NO (1) NO171366C (sv)
NZ (1) NZ225152A (sv)
PH (1) PH25531A (sv)
PT (1) PT87990B (sv)
SU (1) SU1738088A3 (sv)
TN (1) TNSN88073A1 (sv)
ZA (1) ZA885151B (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1317940C (en) * 1987-09-25 1993-05-18 Georges H. P. Van Daele Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
GB9005014D0 (en) 1990-03-06 1990-05-02 Janssen Pharmaceutica Nv N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
JP2524420B2 (ja) * 1990-05-16 1996-08-14 明治製菓株式会社 ピペリジン誘導体及びそれらを有効成分とする抗潰瘍剤
US5082847A (en) * 1990-07-18 1992-01-21 Syntex (U.S.A.) Inc. Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility
US6096761A (en) * 1996-02-15 2000-08-01 Janssen Pharmaceutica N.V. Esters of 3-hydroxy-piperidinemethanol derivatives
NZ330263A (en) * 1996-02-15 1999-06-29 Janssen Pharmaceutica Nv Esters of 3-hydroxy-piperidinemethanol derivatives to improve gastric emptying
TW548103B (en) 1997-07-11 2003-08-21 Janssen Pharmaceutica Nv Bicyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
CN1196681C (zh) * 1997-07-11 2005-04-13 詹森药业有限公司 (+)诺西沙必利用于制备5－ht3和5ht4 介导的疾病的药物中的用途
TW570920B (en) * 1998-12-22 2004-01-11 Janssen Pharmaceutica Nv 4-(aminomethyl)-piperidine benzamides for treating gastrointestinal disorders
DK2194053T3 (da) * 2004-01-07 2013-07-01 Armetheon Inc Methoxypiperidinderivater til brug i behandling af gastrointestinale forstyrrelser og forstyrrelser i centralnervesystemet.
KR100976063B1 (ko) * 2007-03-16 2010-08-17 동아제약주식회사 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법
CN110950843B (zh) * 2019-11-28 2022-12-27 广东东阳光药业有限公司 取代的苯酰胺衍生物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1183847A (en) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
ZW12187A1 (en) * 1986-07-03 1989-02-01 Janssen Pharmaceutica Nv 4-(aroylamino)piperidinebutanamide derivatives
CA1317940C (en) * 1987-09-25 1993-05-18 Georges H. P. Van Daele Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides

Also Published As

Publication number Publication date
NO883171D0 (no) 1988-07-15
AU608338B2 (en) 1991-03-28
CN1020900C (zh) 1993-05-26
PT87990B (pt) 1995-03-01
NO171366B (no) 1992-11-23
FI883378A0 (sv) 1988-07-15
IE882170L (en) 1989-01-17
IL87129A0 (en) 1988-12-30
DE3851388D1 (de) 1994-10-13
DE3851388T2 (de) 1995-01-19
EP0299566B1 (en) 1994-09-07
SU1738088A3 (ru) 1992-05-30
NO883171L (no) 1989-01-18
DK396088D0 (da) 1988-07-15
HU201926B (en) 1991-01-28
DK396088A (da) 1989-01-18
KR970011156B1 (ko) 1997-07-07
FI883378A (sv) 1989-01-18
ES2064341T3 (es) 1995-02-01
JP2642955B2 (ja) 1997-08-20
JPS6445382A (en) 1989-02-17
TNSN88073A1 (fr) 1990-07-10
CA1317951C (en) 1993-05-18
ATE111098T1 (de) 1994-09-15
IL87129A (en) 1993-03-15
BG48809A3 (en) 1991-05-15
AU1906788A (en) 1989-01-19
KR890002108A (ko) 1989-04-08
NZ225152A (en) 1990-04-26
EP0299566A2 (en) 1989-01-18
FI94049C (sv) 1995-07-10
IE64469B1 (en) 1995-08-09
NO171366C (no) 1993-03-03
PT87990A (pt) 1989-06-30
PH25531A (en) 1991-07-24
CN1030753A (zh) 1989-02-01
MA21327A1 (fr) 1989-04-01
EP0299566A3 (en) 1990-08-08
ZA885151B (en) 1990-03-28
HUT49345A (en) 1989-09-28

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: JANSSEN PHARMACEUTICA N.V.