FI934874A - Stereoselektiv reducering av ketoner - Google Patents

Stereoselektiv reducering av ketoner Download PDF

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Publication number
FI934874A
FI934874A FI934874A FI934874A FI934874A FI 934874 A FI934874 A FI 934874A FI 934874 A FI934874 A FI 934874A FI 934874 A FI934874 A FI 934874A FI 934874 A FI934874 A FI 934874A
Authority
FI
Finland
Prior art keywords
ketone
stereoselective reduction
stereoselective
reduction
Prior art date
Application number
FI934874A
Other languages
English (en)
Other versions
FI934874A0 (fi
Inventor
Ramesh N Patel
Amit Banerjee
Clyde Mcnamee
Laszlo J Szarka
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of FI934874A0 publication Critical patent/FI934874A0/fi
Publication of FI934874A publication Critical patent/FI934874A/fi

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00Preparation of sulfur-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/872Nocardia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/931Mucor
FI934874A 1992-11-05 1993-11-04 Stereoselektiv reducering av ketoner FI934874A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97228692A 1992-11-05 1992-11-05

Publications (2)

Publication Number Publication Date
FI934874A0 FI934874A0 (fi) 1993-11-04
FI934874A true FI934874A (fi) 1994-05-06

Family

ID=25519464

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934874A FI934874A (fi) 1992-11-05 1993-11-04 Stereoselektiv reducering av ketoner

Country Status (11)

Country Link
US (1) US5391495A (fi)
EP (1) EP0596490A3 (fi)
JP (1) JPH06233695A (fi)
KR (1) KR940011636A (fi)
CN (1) CN1091472A (fi)
AU (1) AU5044393A (fi)
CA (1) CA2103932A1 (fi)
FI (1) FI934874A (fi)
HU (1) HUT67410A (fi)
IL (1) IL107312A0 (fi)
MX (1) MX9306727A (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10507631A (ja) * 1994-09-22 1998-07-28 ローン−プーラン・ニユトリシヨン・アニマル 4−メチルチオブチロニトリルの酵素による加水分解
CN1057758C (zh) * 1995-01-10 2000-10-25 法玛西雅厄普约翰美国公司 抗心律失常的甲磺酰胺(s)-对映体
US5874475A (en) * 1995-12-21 1999-02-23 Pharmacia & Upjohn Company Antiarrhythmic (S)-enantiomers of methanesulfonamides
US5534422A (en) * 1995-05-19 1996-07-09 Merck & Co., Inc. Bioconversion of beta keto-ester to (R) hydroxyester
US5900368A (en) * 1996-09-17 1999-05-04 Merck & Co., Inc. Process for bioreduction of bisaryl ketone to bisaryl alcohol
US5807926A (en) * 1996-10-11 1998-09-15 Mcgill University Immobilized cofactor-dependent enzymes
JP4012299B2 (ja) 1998-02-25 2007-11-21 ダイセル化学工業株式会社 ハロゲン置換を含む光学活性アルコールの製造方法
US20020042124A1 (en) * 2000-08-16 2002-04-11 Patel Ramesh N. Stereoselective reduction of substituted oxo-butanes
WO2002077258A1 (en) 2001-03-22 2002-10-03 Bristol-Myers Squibb Company Stereoselective reduction of substituted acetophenone
JP2003000290A (ja) * 2001-06-25 2003-01-07 Kanegafuchi Chem Ind Co Ltd 光学活性(r)−2−クロロ−1−(3′−クロロフェニル)エタノールの製造法
WO2003072726A2 (en) * 2002-02-22 2003-09-04 The Board Of Trustees Of The University Of Illinois Nad phosphite oxidoreductase a novel catalyst from bacteria for regeneration of nad(p)h
DE10248277A1 (de) * 2002-10-16 2004-05-06 X-Zyme Gmbh Verfahren zur Herstellung optisch aktiver Verbindungen
KR20080072105A (ko) * 2004-08-26 2008-08-05 화이자 인코포레이티드 단백질 티로신 키나제 저해제 중간체의 제조를 위한거울상이성질선택적 생물학적 전환
DE102005021241B3 (de) * 2005-05-09 2006-11-16 Technische Universität München Verfahren zur Herstellung von organischen Verbindungen
US7582468B2 (en) * 2005-05-25 2009-09-01 Bristol-Myers Squibb Company Process for preparing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof
WO2006130657A2 (en) * 2005-05-31 2006-12-07 Bristol-Myers Squibb Company Stereoselective reduction process for the preparation of pyrrolotriazine compounds
AT504542B1 (de) * 2006-12-07 2008-09-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von secodionderivaten
ATE500820T1 (de) * 2007-06-22 2011-03-15 Bristol Myers Squibb Co Tablettierte atazanavirhaltige zusammensetzungen
US20100183715A1 (en) * 2007-06-22 2010-07-22 Bristo-Meyers Squibb Company Tableted compositions containing atazanavir
WO2009002823A2 (en) * 2007-06-22 2008-12-31 Bristol-Myers Squibb Company Tableted compositions containing atazanavir
EP2178513B1 (en) * 2007-06-22 2011-03-30 Bristol-Myers Squibb Company Tableted compositions containing atazanavir
SI2329014T1 (sl) * 2008-08-29 2015-01-30 Codexis, Inc. Polipeptidi ketoreduktaze za stereoselektivno produkcijo (4s)-3(5s)-5(4-fluorofenil)-5-hidroksipentanoil)-4-fenil-1,3-oksazolidin -2-ona
CN101760436B (zh) * 2008-12-26 2011-12-07 安琪酵母股份有限公司 一种酵母菌株,制备方法及其相关应用
WO2010150946A1 (en) * 2009-06-22 2010-12-29 Sk Holdings Co., Ltd. Method for preparation of carbamic acid (r)-1-aryl-2-tetrazolyl-ethyl ester
US8404461B2 (en) * 2009-10-15 2013-03-26 SK Biopharmaceutical Co. Ltd. Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester
JP2014520536A (ja) 2011-07-13 2014-08-25 フードチェク・システムズ・インコーポレイテッド リステリアを培養するための培養培地、方法、およびリステリアを検出するための方法
CN111019981A (zh) * 2019-12-27 2020-04-17 蚌埠丰原医药科技发展有限公司 不对称法合成r-去甲肾上腺素的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342584A (en) * 1963-07-10 1967-09-19 Ansul Co Method for killing broadleaf and grassy weeds in cotton
US4857468A (en) * 1985-04-13 1989-08-15 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing optically active 2-halo-1-phenyl ethanol
DE3724197A1 (de) * 1987-07-22 1989-02-02 Merck Patent Gmbh Verfahren zur reduktion von ketonen
US5106736A (en) * 1991-04-23 1992-04-21 E.R. Squibb & Sons, Inc. Enzymatic process for enantiomer-specific perparation of mercapto alkanoic acid compounds

Also Published As

Publication number Publication date
AU5044393A (en) 1994-05-19
EP0596490A3 (en) 1995-04-26
IL107312A0 (en) 1994-01-25
EP0596490A2 (en) 1994-05-11
US5391495A (en) 1995-02-21
CN1091472A (zh) 1994-08-31
KR940011636A (ko) 1994-06-21
MX9306727A (es) 1994-06-30
JPH06233695A (ja) 1994-08-23
FI934874A0 (fi) 1993-11-04
HU9303130D0 (en) 1994-01-28
CA2103932A1 (en) 1994-05-06
HUT67410A (en) 1995-04-28

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