FI933441A - Flytande tromboplastinreagens - Google Patents

Flytande tromboplastinreagens Download PDF

Info

Publication number
FI933441A
FI933441A FI933441A FI933441A FI933441A FI 933441 A FI933441 A FI 933441A FI 933441 A FI933441 A FI 933441A FI 933441 A FI933441 A FI 933441A FI 933441 A FI933441 A FI 933441A
Authority
FI
Finland
Prior art keywords
thromboplastin reagents
thromboplastin
reagents
reagent
months
Prior art date
Application number
FI933441A
Other languages
English (en)
Other versions
FI109152B (fi
FI933441A0 (fi
Inventor
James Rhett Butler
Juan Louis Torres
Rajesh Sharma
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25449889&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI933441(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI933441A0 publication Critical patent/FI933441A0/fi
Publication of FI933441A publication Critical patent/FI933441A/fi
Application granted granted Critical
Publication of FI109152B publication Critical patent/FI109152B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/7454—Tissue factor (tissue thromboplastin, Factor III)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI933441A 1992-08-03 1993-08-02 Stabiili nestemäinen tromboplastiinireagenssi, menetelmä sen valmistamiseksi sekä reagenssin sisältävä diagnostinen välineistö FI109152B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92421192 1992-08-03
US07/924,211 US5358853A (en) 1992-08-03 1992-08-03 Liquid thromboplastin reagent

Publications (3)

Publication Number Publication Date
FI933441A0 FI933441A0 (fi) 1993-08-02
FI933441A true FI933441A (fi) 1994-02-04
FI109152B FI109152B (fi) 2002-05-31

Family

ID=25449889

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933441A FI109152B (fi) 1992-08-03 1993-08-02 Stabiili nestemäinen tromboplastiinireagenssi, menetelmä sen valmistamiseksi sekä reagenssin sisältävä diagnostinen välineistö

Country Status (13)

Country Link
US (2) US5358853A (fi)
EP (1) EP0585987B2 (fi)
JP (1) JP3330685B2 (fi)
KR (1) KR100265531B1 (fi)
AT (1) ATE179759T1 (fi)
AU (1) AU665432B2 (fi)
CA (1) CA2100617C (fi)
DE (2) DE69324745D1 (fi)
DK (1) DK0585987T4 (fi)
ES (1) ES2132174T5 (fi)
FI (1) FI109152B (fi)
GR (1) GR3030728T3 (fi)
ZA (1) ZA935180B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
AU7129598A (en) * 1997-04-23 1998-11-13 Instrumentation Laboratory S.P.A. Recombinant rabbit tissue factor based prothrombin time reagent
DE19720853A1 (de) * 1997-05-17 1998-11-19 Dade Behring Marburg Gmbh Erhöhung der FVII Empfindlichkeit eines Thromboplastinreagenzes
DE19811016A1 (de) * 1998-03-13 1999-09-16 Dade Behring Marburg Gmbh Gebrauchsfertiges Prothrombinzeitreagenz auf der Basis von rekombinantem Gewebsfaktor
US6391609B1 (en) 1998-10-07 2002-05-21 Sigma-Aldrich Co. Thromboplastin reagents and methods for preparing and using such reagents
US6207661B1 (en) 1999-02-22 2001-03-27 Baxter International Inc. Premixed formulation of piperacillin sodium and tazobactam sodium injection
US6733985B1 (en) 1999-05-19 2004-05-11 International Technidyne Corporation Preparation of stable liquid and dried synthetic prothrombin time reagents
US6248353B1 (en) 1999-12-10 2001-06-19 Dade Behring Inc. Reconstitution of purified membrane proteins into preformed liposomes
US6855509B2 (en) 2000-12-19 2005-02-15 Instrumentation Laboratory Company Protein S functional assay and kit therefor
US7148067B2 (en) * 2004-08-31 2006-12-12 The Board Of Trustees Of The University Of Illinois Thromboplastin reagents
CN101151533A (zh) * 2005-02-16 2008-03-26 伊利诺斯大学理事会 基于金属螯合脂质的促凝血剂
ATE505488T1 (de) * 2005-03-04 2011-04-15 Univ Illinois Modulator von coagulationskaskaden und fibrinolytischen kaskaden
CA2649538C (en) * 2006-04-21 2014-06-03 Yatin Gokarn Buffering agents for biopharmaceutical formulations
JP4999613B2 (ja) * 2007-08-31 2012-08-15 シスメックス株式会社 血液凝固測定用試薬及び血液凝固時間測定方法
WO2009046194A2 (en) * 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
WO2009061697A1 (en) * 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
DE102007062323A1 (de) 2007-12-21 2009-06-25 Siemens Healthcare Diagnostics Products Gmbh Langzeitstabiles Thromboplastin-Reagenz
WO2010134345A1 (ja) 2009-05-20 2010-11-25 積水メディカル株式会社 血液凝固時間延長剤
JP5589103B2 (ja) * 2013-01-23 2014-09-10 株式会社Ｌｓｉメディエンス 二価金属イオン含有の体外診断用試薬組成物および二価金属イオン由来金属化合物の沈殿防止方法
JP6250306B2 (ja) * 2013-05-28 2017-12-20 株式会社Ｌｓｉメディエンス リポ化トロンボプラスチン含有血液凝固能測定試薬及び測定方法
JP2014197019A (ja) * 2014-06-30 2014-10-16 積水メディカル株式会社 血液凝固反応における血液凝固時間延長剤
WO2017139567A1 (en) 2016-02-12 2017-08-17 Instrumentation Laboratory Company A two component "mix and use" liquid thromboplastin reagent, methods of making, and methods of use thereof
EP3489692A1 (de) 2017-11-28 2019-05-29 Siemens Healthcare Diagnostics Products GmbH Prothrombinzeit-reagenz enthaltend einen eisenchelator
US20210405072A1 (en) * 2018-09-25 2021-12-30 Sekisui Medical Co., Ltd. Method for measuring blood coagulation time
CN113005176A (zh) * 2019-12-20 2021-06-22 深圳市帝迈生物技术有限公司 稳定剂、凝血酶原时间检测试剂及其制备方法、试剂盒
CN111638374B (zh) * 2020-06-08 2022-10-18 深圳市国赛生物技术有限公司 一种用于测定凝血酶原时间的体外诊断试剂盒

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2516216A (en) * 1947-06-24 1950-07-25 Sharp & Dohme Inc Thromboplastin as testing agent
US2842480A (en) * 1954-05-27 1958-07-08 Ortho Pharma Corp Preparation of thromboplastin
US2847350A (en) * 1954-05-27 1958-08-12 Ortho Pharma Corp Preparation of highly active thromboplastin
US2847347A (en) * 1954-05-27 1958-08-12 Ortho Pharmacentical Corp Preparation of improved thromboplastin
US2921000A (en) * 1956-05-22 1960-01-12 Ortho Pharma Corp Thromboplastin
US3522148A (en) * 1965-08-13 1970-07-28 Dade Reagents Inc Stabilized thromboplastin preparation
DE3113350A1 (de) * 1981-04-02 1982-10-21 Boehringer Mannheim Gmbh, 6800 Mannheim Reagens zur optischen bestimmung des blutgerinnungsverhaltens
DE3150596A1 (de) * 1981-12-21 1983-06-30 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von gewebsthromboplastin
US4755461A (en) * 1986-04-17 1988-07-05 Bio/Data Corporation Tableted blood plasma microconcentrated thromboplastin coagulation reagent
WO1990005740A1 (en) * 1988-11-23 1990-05-31 Baxter International Inc. Improved extraction methods for preparing thromboplastin reagents
US5270451A (en) * 1988-11-23 1993-12-14 Baxter Diagnostics Inc. Extraction method for preparing thromboplastin reagents
US5091304A (en) * 1989-08-21 1992-02-25 International Technidyne Corporation Whole blood activated partial thromboplastin time test and associated apparatus
DE3929329A1 (de) * 1989-09-04 1991-03-07 Behringwerke Ag Stabilisierungsmittel zur verbesserung der wiederfindung von gerinnungsfaktoren in blutproben
US5281528A (en) * 1989-12-18 1994-01-25 Warner-Lambert Company Process for purified thromboplastin for ultra-pure thrombin preparation
FR2679251B1 (fr) * 1991-07-18 1993-11-12 Nord Assoc Essor Transfusion San Procede de preparation d'un concentre de thrombine humaine destine a un usage therapeutique.

Also Published As

Publication number Publication date
DK0585987T4 (da) 2005-01-17
DE69324745T2 (de) 1999-10-14
US5508170A (en) 1996-04-16
CA2100617A1 (en) 1994-02-04
ATE179759T1 (de) 1999-05-15
FI109152B (fi) 2002-05-31
EP0585987B2 (en) 2004-09-08
CA2100617C (en) 2003-06-24
FI933441A0 (fi) 1993-08-02
DE69324745D1 (de) 1999-06-10
EP0585987B1 (en) 1999-05-06
GR3030728T3 (en) 1999-11-30
JP3330685B2 (ja) 2002-09-30
US5358853A (en) 1994-10-25
KR940005288A (ko) 1994-03-21
DE69324745T4 (de) 2006-01-05
ZA935180B (en) 1994-05-25
AU4215893A (en) 1994-02-10
AU665432B2 (en) 1996-01-04
ES2132174T3 (es) 1999-08-16
DK0585987T3 (da) 1999-11-08
EP0585987A1 (en) 1994-03-09
JPH06201702A (ja) 1994-07-22
ES2132174T5 (es) 2005-04-16
KR100265531B1 (ko) 2000-09-15

Similar Documents

Publication Publication Date Title
FI933441A (fi) Flytande tromboplastinreagens
DE59410066D1 (de) System zur Analyse von Inhaltsstoffen flüssiger Proben
GR3019992T3 (en) Method for improving measurement precision in evanescent wave optical biosensor assays.
DE69022819T2 (de) Verbindungen und Reagenzien zur Bestimmung von Retikulozyten.
AU564622B2 (en) Diagnostic activated partial thrombo plastin reagent
DK603087D0 (da) Immunokemisk metod tilbestemmelse af stabilt glycosyleret haemoglobin
DK162179C (da) Reagens til ettrinsbestemmelse af den aktiverede partielle thromboplastintid samt reagensets anvendelse
DE69328951T2 (de) Nukleinsäuresonden für Mykobacterium Tuberkulosis
BR8601070A (pt) Processo de determinar oticamente,mostrar isoladamente e/ou localizar pelo menos um objeto
DE69124030T2 (de) Testverfahren, die ein lösliches fibrinähnliches Monomer nutzen
FR2599149B1 (fr) Reactif pour la transparisation de milieux biologiques et ses applications analytiques.
DE3263152D1 (en) Reagents for determining the ristocetin cofactor (von willebrand's factor)
DK0535347T3 (fi)
EP0217768A3 (en) Method and compositions for heparin assays
DE69016485D1 (de) Vorrichtung zur getrennten Zugabe von Reagenzien.
DK0570355T3 (da) Anvendelse af prothrombin-fragmenter
ATE83930T1 (de) Antikoerper enthaltende stabilisierte waesserige zusammensetzung.
ATE98266T1 (de) Polymermodifizierung.
IT1230150B (it) Reattivo per la determinazione analitica dell'enzima gamma glutamiltransferasi.
ATE94087T1 (de) Belueftung von fluessigkeiten.

Legal Events

Date Code Title Description
MA Patent expired